STRINGSTRING
FGF5 FGF5 PPP2CB PPP2CB SHC1 SHC1 BRAF BRAF FNDC3B FNDC3B GAB1 GAB1 FLRT2 FLRT2 FLRT3 FLRT3 FNDC3A FNDC3A ANOS1 ANOS1 KRAS KRAS PIK3CA PIK3CA PLCG1 PLCG1 CSDE1 CSDE1 HRAS HRAS SOS1 SOS1 PTPN11 PTPN11 FGFRL1 FGFRL1 FRS3 FRS3 RPS27A RPS27A ENSTSYP00000014559 ENSTSYP00000014559 FGF6 FGF6 FGF3 FGF3 FRS2 FRS2 PPP2R1A PPP2R1A ENSTSYP00000017997 ENSTSYP00000017997 FGF1 FGF1 PPP2CA PPP2CA ENSTSYP00000019212 ENSTSYP00000019212 ENSTSYP00000020188 ENSTSYP00000020188 FGF20 FGF20 FGF20-2 FGF20-2 FGF17 FGF17 PIK3R1 PIK3R1 FGF10 FGF10 FGF9 FGF9 ENSTSYP00000022222 ENSTSYP00000022222 FGFR1 FGFR1 UBA52 UBA52 ENSTSYP00000024219 ENSTSYP00000024219 NRAS NRAS KL KL FGF18 FGF18 SPRED1 SPRED1 SPRED2 SPRED2 ENSTSYP00000027147 ENSTSYP00000027147 MAPK3 MAPK3 MKNK1 MKNK1 CBL CBL ENSTSYP00000030676 ENSTSYP00000030676 MAPK1 MAPK1 GRAP GRAP GRB2 GRB2 ENSTSYP00000033115 ENSTSYP00000033115 SRC SRC LOC110596262 LOC110596262 SPRY2 SPRY2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FGF5Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (268 aa)
PPP2CBSerine/threonine-protein phosphatase. (309 aa)
SHC1SHC-transforming protein 1 isoform X1. (474 aa)
BRAFSerine/threonine-protein kinase B-raf. (760 aa)
FNDC3BFibronectin type III domain-containing protein 3B. (1203 aa)
GAB1GRB2-associated-binding protein 1 isoform X1. (700 aa)
FLRT2Leucine-rich repeat transmembrane protein FLRT2. (660 aa)
FLRT3Leucine-rich repeat transmembrane protein FLRT3. (649 aa)
FNDC3AFibronectin type-III domain-containing protein 3A isoform X1. (1196 aa)
ANOS1Anosmin-1. (595 aa)
KRASGTPase KRas isoform X1. (189 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1302 aa)
CSDE1Cold shock domain-containing protein E1 isoform X1. (842 aa)
HRASGTPase HRas isoform X6. (189 aa)
SOS1Son of sevenless homolog 1 isoform X2. (441 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type 11. (532 aa)
FGFRL1Fibroblast growth factor receptor-like 1. (506 aa)
FRS3Fibroblast growth factor receptor substrate 3 isoform X1. (492 aa)
RPS27Aubiquitin-40S ribosomal protein S27a. (156 aa)
ENSTSYP00000014559annotation not available (115 aa)
FGF6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
FGF3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (172 aa)
FRS2Fibroblast growth factor receptor substrate 2. (508 aa)
PPP2R1ASerine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform isoform X1. (589 aa)
ENSTSYP00000017997annotation not available (123 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
ENSTSYP00000019212annotation not available (259 aa)
ENSTSYP00000020188annotation not available (70 aa)
FGF20Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (115 aa)
FGF20-2Fibroblast growth factor 20. (75 aa)
FGF17Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (205 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (612 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (146 aa)
ENSTSYP00000022222annotation not available (155 aa)
FGFR1Fibroblast growth factor receptor. (832 aa)
UBA52ubiquitin-60S ribosomal protein L40 isoform X1. (231 aa)
ENSTSYP00000024219annotation not available (592 aa)
NRASGTPase NRas. (189 aa)
KLKlotho; Belongs to the glycosyl hydrolase 1 family. (972 aa)
FGF18Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (184 aa)
SPRED1Sprouty-related, EVH1 domain-containing protein 1. (443 aa)
SPRED2Sprouty-related, EVH1 domain-containing protein 2. (427 aa)
ENSTSYP00000027147annotation not available (149 aa)
MAPK3Mitogen-activated protein kinase. (363 aa)
MKNK1MAP kinase-interacting serine/threonine-protein kinase 1 isoform X1; Belongs to the protein kinase superfamily. (445 aa)
CBLE3 ubiquitin-protein ligase CBL. (898 aa)
ENSTSYP00000030676annotation not available (108 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (363 aa)
GRAPGRB2-related adapter protein. (188 aa)
GRB2Growth factor receptor-bound protein 2 isoform X1. (217 aa)
ENSTSYP00000033115annotation not available (96 aa)
SRCTyrosine-protein kinase. (542 aa)
LOC110596262ubiquitin-40S ribosomal protein S27a-like. (156 aa)
SPRY2Protein sprouty homolog 2. (338 aa)
Your Current Organism:
Carlito syrichta
NCBI taxonomy Id: 1868482
Other names: C. syrichta, Philippine tarsier, Tarsius syrichta
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