118 items (Carlito syrichta) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CDC25A	M-phase inducer phosphatase 1 isoform X1. (523 aa)
	ENSTSYP00000035030	annotation not available (263 aa)
	PSMD8	26S proteasome non-ATPase regulatory subunit 8. (264 aa)
	RBL2	Retinoblastoma-like protein 2 isoform X1. (1141 aa)
	ENSTSYP00000034042	annotation not available (110 aa)
	CDK2	Cyclin-dependent kinase 2 isoform X1; Belongs to the protein kinase superfamily. (346 aa)
	LOC110596262	ubiquitin-40S ribosomal protein S27a-like. (156 aa)
	PSMA3	Proteasome subunit alpha type. (255 aa)
	ENSTSYP00000033058	annotation not available (142 aa)
	PSMC4	26S protease regulatory subunit 6B isoform X1; Belongs to the AAA ATPase family. (418 aa)
	ENSTSYP00000032718	annotation not available (175 aa)
	PSME2	Proteasome activator complex subunit 2 isoform X1. (254 aa)
	ENSTSYP00000032262	annotation not available (99 aa)
	PSMB5	Proteasome subunit beta. (263 aa)
	PSMA2	Proteasome subunit alpha type. (234 aa)
	ENSTSYP00000031721	annotation not available (275 aa)
	AKT1	Non-specific serine/threonine protein kinase. (393 aa)
	LOC103262238	Proteasome subunit alpha type. (261 aa)
	PSMB8	Proteasome subunit beta. (276 aa)
	MYC	Myc proto-oncogene protein. (376 aa)
	ENSTSYP00000030676	annotation not available (108 aa)
	ENSTSYP00000030504	annotation not available (156 aa)
	ENSTSYP00000029471	annotation not available (82 aa)
	LOC103250392	26S protease regulatory subunit 7; Belongs to the AAA ATPase family. (400 aa)
	ENSTSYP00000028770	annotation not available (118 aa)
	CDKN1B	LOW QUALITY PROTEIN: cyclin-dependent kinase inhibitor 1B. (197 aa)
	ENSTSYP00000028450	annotation not available (227 aa)
	ENSTSYP00000028373	annotation not available (134 aa)
	PSMC5	26S protease regulatory subunit 8 isoform X2; Belongs to the AAA ATPase family. (398 aa)
	ENSTSYP00000027311	annotation not available (388 aa)
	CDKN1A	Cyclin-dependent kinase inhibitor 1. (164 aa)
	ENSTSYP00000027147	annotation not available (149 aa)
	ENSTSYP00000027087	annotation not available (52 aa)
	PSMB10	Proteasome subunit beta. (273 aa)
	MNAT1	CDK-activating kinase assembly factor MAT1. (169 aa)
	PSMD13	26S proteasome non-ATPase regulatory subunit 13 isoform X1. (396 aa)
	ENSTSYP00000025727	annotation not available (215 aa)
	PSMD9	26S proteasome non-ATPase regulatory subunit 9 isoform X1. (220 aa)
	PSMD4	26S proteasome non-ATPase regulatory subunit 4 isoform X2. (377 aa)
	ENSTSYP00000025346	annotation not available (194 aa)
	ENSTSYP00000024947	annotation not available (143 aa)
	ENSTSYP00000024485	annotation not available (234 aa)
	E2F1	Transcription factor E2F1. (350 aa)
	UBA52	ubiquitin-60S ribosomal protein L40 isoform X1. (231 aa)
	ENSTSYP00000023689	annotation not available (139 aa)
	ENSTSYP00000023430	annotation not available (374 aa)
	CCNE2	G1/S-specific cyclin-E2 isoform X1; Belongs to the cyclin family. (404 aa)
	LIN54	Protein lin-54 homolog isoform X1. (749 aa)
	CCND1	G1/S-specific cyclin-D1. (156 aa)
	ENSTSYP00000022222	annotation not available (155 aa)
	ENSTSYP00000021540	annotation not available (291 aa)
	PSME3	Proteasome activator complex subunit 3 isoform X1. (265 aa)
	ENSTSYP00000021013	annotation not available (135 aa)
	ENSTSYP00000020949	annotation not available (151 aa)
	SKP2	S-phase kinase-associated protein 2. (436 aa)
	PSMB6	Proteasome subunit beta. (242 aa)
	PSMD10	26S proteasome non-ATPase regulatory subunit 10 isoform X1. (226 aa)
	ENSTSYP00000019245	annotation not available (285 aa)
	ENSTSYP00000019039	annotation not available (232 aa)
	CABLES1	CDK5 and ABL1 enzyme substrate 1. (367 aa)
	KIAA2012	LOW QUALITY PROTEIN: uncharacterized protein KIAA2012 homolog; Belongs to the eukaryotic ribosomal protein P1/P2 family. (1143 aa)
	ENSTSYP00000017997	annotation not available (123 aa)
	PTK6	Tyrosine-protein kinase. (450 aa)
	ENSTSYP00000016249	annotation not available (98 aa)
	ENSTSYP00000016214	annotation not available (88 aa)
	CUL1	Cullin-1 isoform X1; Belongs to the cullin family. (776 aa)
	PSMC3	26S protease regulatory subunit 6A; Belongs to the AAA ATPase family. (450 aa)
	CDK3	Cyclin-dependent kinase 3 isoform X1; Belongs to the protein kinase superfamily. (305 aa)
	ENSTSYP00000015668	annotation not available (251 aa)
	AKT2	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
	CKS1B	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa)
	LIN37	Protein lin-37 homolog isoform X2. (246 aa)
	ENSTSYP00000014559	annotation not available (115 aa)
	PSMA6	Proteasome subunit alpha type. (246 aa)
	MAX	Protein max isoform X1. (160 aa)
	CKS2	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa)
	E2F5	Transcription factor E2F5 isoform X1. (300 aa)
	PSMD12	26S proteasome non-ATPase regulatory subunit 12. (420 aa)
	PSMD1	26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (623 aa)
	PSMB3	Proteasome subunit beta. (207 aa)
	PSMD3	26S proteasome non-ATPase regulatory subunit 3 isoform X2. (534 aa)
	PSMB7	Proteasome subunit beta. (277 aa)
	PSMD11	26S proteasome non-ATPase regulatory subunit 11. (422 aa)
	CDK4	Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa)
	PSMD6	26S proteasome non-ATPase regulatory subunit 6 isoform X1. (416 aa)
	WEE1	Wee1-like protein kinase. (432 aa)
	CCNH	cyclin-H; Belongs to the cyclin family. (232 aa)
	AKT3	RAC-gamma serine/threonine-protein kinase; Belongs to the protein kinase superfamily. (419 aa)
	PSMA7	Proteasome endopeptidase complex. (248 aa)
	PSMD5	26S proteasome non-ATPase regulatory subunit 5 isoform X1. (513 aa)
	SKP1	S-phase kinase-associated protein 1 isoform X2; Belongs to the SKP1 family. (163 aa)
	ENSTSYP00000009770	annotation not available (227 aa)
	PSMC6	26S protease regulatory subunit 10B; Belongs to the AAA ATPase family. (403 aa)
	TFDP2	Transcription factor. (448 aa)
	CDK7	Cyclin-dependent kinase 7 isoform X1. (332 aa)
	LOC103272535	26S proteasome non-ATPase regulatory subunit 7. (324 aa)
	PSMB4	Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
	PSMC1	26S protease regulatory subunit 4; Belongs to the AAA ATPase family. (440 aa)
	PSMB9	Proteasome subunit beta. (219 aa)
	E2F4	Transcription factor E2F4. (407 aa)
	LIN9	Protein lin-9 homolog isoform X1. (580 aa)
	CCNA1	cyclin-A1; Belongs to the cyclin family. (455 aa)
	PSMB2	Proteasome subunit beta. (201 aa)
	PSME1	Proteasome activator complex subunit 1 isoform X1. (250 aa)
	PSMF1	Proteasome inhibitor PI31 subunit isoform X2. (272 aa)
	PSMA4	Proteasome subunit alpha type. (179 aa)
	CCNE1	G1/S-specific cyclin-E1. (410 aa)
	PSMD14	26S proteasome non-ATPase regulatory subunit 14. (326 aa)
	PSMD2	26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa)
	PSMA1	Proteasome subunit alpha type. (264 aa)
	CCNA2	cyclin-A2; Belongs to the cyclin family. (430 aa)
	WEE2	Wee1-like protein kinase. (567 aa)
	LIN52	Protein lin-52 homolog. (106 aa)
	RB1	Retinoblastoma-associated protein. (929 aa)
	PSMB1	Proteasome subunit beta. (241 aa)
	RPS27A	ubiquitin-40S ribosomal protein S27a. (156 aa)
	PSMA5	Proteasome subunit alpha type. (241 aa)
	ENSTSYP00000000614	annotation not available (191 aa)

Your Current Organism:

Carlito syrichta

NCBI taxonomy Id: 1868482
Other names: C. syrichta, Philippine tarsier, Tarsius syrichta

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKT1	AKT2	ENSTSYP00000030955	ENSTSYP00000014890	Non-specific serine/threonine protein kinase.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.975
AKT1	AKT3	ENSTSYP00000030955	ENSTSYP00000010131	Non-specific serine/threonine protein kinase.	RAC-gamma serine/threonine-protein kinase; Belongs to the protein kinase superfamily.	0.910
AKT1	CCNA1	ENSTSYP00000030955	ENSTSYP00000005458	Non-specific serine/threonine protein kinase.	cyclin-A1; Belongs to the cyclin family.	0.417
AKT1	CCNA2	ENSTSYP00000030955	ENSTSYP00000002463	Non-specific serine/threonine protein kinase.	cyclin-A2; Belongs to the cyclin family.	0.478
AKT1	CCND1	ENSTSYP00000030955	ENSTSYP00000022614	Non-specific serine/threonine protein kinase.	G1/S-specific cyclin-D1.	0.671
AKT1	CCNE1	ENSTSYP00000030955	ENSTSYP00000004441	Non-specific serine/threonine protein kinase.	G1/S-specific cyclin-E1.	0.538
AKT1	CDK2	ENSTSYP00000030955	ENSTSYP00000033464	Non-specific serine/threonine protein kinase.	Cyclin-dependent kinase 2 isoform X1; Belongs to the protein kinase superfamily.	0.455
AKT1	CDK4	ENSTSYP00000030955	ENSTSYP00000010949	Non-specific serine/threonine protein kinase.	Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily.	0.433
AKT1	CDKN1A	ENSTSYP00000030955	ENSTSYP00000027188	Non-specific serine/threonine protein kinase.	Cyclin-dependent kinase inhibitor 1.	0.978
AKT1	CDKN1B	ENSTSYP00000030955	ENSTSYP00000028621	Non-specific serine/threonine protein kinase.	LOW QUALITY PROTEIN: cyclin-dependent kinase inhibitor 1B.	0.981
AKT1	CUL1	ENSTSYP00000030955	ENSTSYP00000016060	Non-specific serine/threonine protein kinase.	Cullin-1 isoform X1; Belongs to the cullin family.	0.685
AKT1	E2F1	ENSTSYP00000030955	ENSTSYP00000023955	Non-specific serine/threonine protein kinase.	Transcription factor E2F1.	0.499
AKT1	ENSTSYP00000014559	ENSTSYP00000030955	ENSTSYP00000014559	Non-specific serine/threonine protein kinase.	annotation not available	0.438
AKT1	ENSTSYP00000017997	ENSTSYP00000030955	ENSTSYP00000017997	Non-specific serine/threonine protein kinase.	annotation not available	0.412
AKT1	ENSTSYP00000030676	ENSTSYP00000030955	ENSTSYP00000030676	Non-specific serine/threonine protein kinase.	annotation not available	0.412
AKT1	ENSTSYP00000035030	ENSTSYP00000030955	ENSTSYP00000035030	Non-specific serine/threonine protein kinase.	annotation not available	0.433
AKT1	MYC	ENSTSYP00000030955	ENSTSYP00000030736	Non-specific serine/threonine protein kinase.	Myc proto-oncogene protein.	0.652
AKT1	PTK6	ENSTSYP00000030955	ENSTSYP00000016516	Non-specific serine/threonine protein kinase.	Tyrosine-protein kinase.	0.774
AKT1	SKP2	ENSTSYP00000030955	ENSTSYP00000020853	Non-specific serine/threonine protein kinase.	S-phase kinase-associated protein 2.	0.771
AKT1	UBA52	ENSTSYP00000030955	ENSTSYP00000023912	Non-specific serine/threonine protein kinase.	ubiquitin-60S ribosomal protein L40 isoform X1.	0.412