STRINGSTRING
ENSTSYP00000016249 ENSTSYP00000016249 ENSTSYP00000035030 ENSTSYP00000035030 ENSTSYP00000034921 ENSTSYP00000034921 PSMD8 PSMD8 RBL2 RBL2 MCM4 MCM4 ENSTSYP00000034042 ENSTSYP00000034042 CDK2 CDK2 LOC110596262 LOC110596262 PSMA3 PSMA3 ENSTSYP00000033058 ENSTSYP00000033058 PSMC4 PSMC4 E2F6 E2F6 ENSTSYP00000032718 ENSTSYP00000032718 PSME2 PSME2 ENSTSYP00000032262 ENSTSYP00000032262 PSMB5 PSMB5 PSMA2 PSMA2 ENSTSYP00000031721 ENSTSYP00000031721 RPA3 RPA3 AKT1 AKT1 LOC103262238 LOC103262238 ENSTSYP00000030901 ENSTSYP00000030901 LOC103252110 LOC103252110 PSMB8 PSMB8 MYC MYC ENSTSYP00000030676 ENSTSYP00000030676 ENSTSYP00000030504 ENSTSYP00000030504 LOC103265662 LOC103265662 MCM9 MCM9 ENSTSYP00000029471 ENSTSYP00000029471 LOC103250392 LOC103250392 ENSTSYP00000028770 ENSTSYP00000028770 CDKN1B CDKN1B ENSTSYP00000028450 ENSTSYP00000028450 ENSTSYP00000028373 ENSTSYP00000028373 PSMC5 PSMC5 ENSTSYP00000027311 ENSTSYP00000027311 CDKN1A CDKN1A ENSTSYP00000027147 ENSTSYP00000027147 ENSTSYP00000027087 ENSTSYP00000027087 LOC103272490 LOC103272490 ENSTSYP00000026533 ENSTSYP00000026533 PSMB10 PSMB10 TYMS TYMS PRIM2 PRIM2 MNAT1 MNAT1 HDAC1 HDAC1 PSMD13 PSMD13 ENSTSYP00000025727 ENSTSYP00000025727 PSMD9 PSMD9 PSMD4 PSMD4 LOC103254497 LOC103254497 ENSTSYP00000025346 ENSTSYP00000025346 ENSTSYP00000024958 ENSTSYP00000024958 ENSTSYP00000024947 ENSTSYP00000024947 ENSTSYP00000024485 ENSTSYP00000024485 ENSTSYP00000024219 ENSTSYP00000024219 E2F1 E2F1 UBA52 UBA52 ENSTSYP00000023689 ENSTSYP00000023689 ENSTSYP00000023430 ENSTSYP00000023430 CCNE2 CCNE2 LIN54 LIN54 CCND1 CCND1 ENSTSYP00000022222 ENSTSYP00000022222 MCM3 MCM3 ENSTSYP00000021540 ENSTSYP00000021540 PSME3 PSME3 ENSTSYP00000021013 ENSTSYP00000021013 ENSTSYP00000020949 ENSTSYP00000020949 SKP2 SKP2 PSMB6 PSMB6 CDK1 CDK1 PSMD10 PSMD10 ENSTSYP00000019245 ENSTSYP00000019245 ENSTSYP00000019212 ENSTSYP00000019212 PCNA PCNA ENSTSYP00000019039 ENSTSYP00000019039 CABLES1 CABLES1 CDT1 CDT1 KIAA2012 KIAA2012 ENSTSYP00000017997 ENSTSYP00000017997 PPP2R1A PPP2R1A MEIOB MEIOB ENSTSYP00000017776 ENSTSYP00000017776 CDC45 CDC45 PPP2R1B PPP2R1B PTK6 PTK6 ORC6 ORC6 RPA4 RPA4 ENSTSYP00000016214 ENSTSYP00000016214 CUL1 CUL1 PSMC3 PSMC3 POLE3 POLE3 CDK3 CDK3 ENSTSYP00000015668 ENSTSYP00000015668 ENSTSYP00000015529 ENSTSYP00000015529 CDC25A CDC25A AKT2 AKT2 CKS1B CKS1B LIN37 LIN37 ENSTSYP00000014559 ENSTSYP00000014559 PSMA6 PSMA6 PPP2CA PPP2CA MAX MAX MCM5 MCM5 POLE4 POLE4 CKS2 CKS2 E2F5 E2F5 PPP2CB PPP2CB ORC1 ORC1 FNBP4 FNBP4 PPP2R3A PPP2R3A PSMD12 PSMD12 PSMD1 PSMD1 PSMB3 PSMB3 ORC5 ORC5 PSMD3 PSMD3 FBXO5 FBXO5 PSMB7 PSMB7 PSMD11 PSMD11 CDK4 CDK4 PSMD6 PSMD6 WEE1 WEE1 CCNH CCNH GMNN GMNN AKT3 AKT3 PSMA7 PSMA7 PSMD5 PSMD5 RPA2 RPA2 SKP1 SKP1 RRM2 RRM2 ENSTSYP00000009770 ENSTSYP00000009770 PPP4R1 PPP4R1 POLE POLE ORC2 ORC2 RBL1 RBL1 PSMC6 PSMC6 PPP2R3C PPP2R3C TK1 TK1 TFDP2 TFDP2 ENSTSYP00000008181 ENSTSYP00000008181 CDK7 CDK7 LOC103272535 LOC103272535 MCM10 MCM10 PSMB4 PSMB4 PSMC1 PSMC1 PSMB9 PSMB9 E2F4 E2F4 CDC6 CDC6 ORC4 ORC4 ORC3 ORC3 PRIM1 PRIM1 LIN9 LIN9 RELCH RELCH MCM2 MCM2 TM4SF19 TM4SF19 CCNA1 CCNA1 POLA1 POLA1 PSMB2 PSMB2 PSME1 PSME1 CDC7 CDC7 PSMF1 PSMF1 PSMA4 PSMA4 CCNE1 CCNE1 PSMD14 PSMD14 PPP4R4 PPP4R4 MCM8 MCM8 POLE2 POLE2 PSMD2 PSMD2 PSMA1 PSMA1 RPA1 RPA1 MCM6 MCM6 CCNA2 CCNA2 WEE2 WEE2 LIN52 LIN52 DBF4 DBF4 MCM7 MCM7 RB1 RB1 PSMB1 PSMB1 RPS27A RPS27A PSMA5 PSMA5 ENSTSYP00000000614 ENSTSYP00000000614
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSTSYP00000016249annotation not available (98 aa)
ENSTSYP00000035030annotation not available (263 aa)
ENSTSYP00000034921annotation not available (296 aa)
PSMD826S proteasome non-ATPase regulatory subunit 8. (264 aa)
RBL2Retinoblastoma-like protein 2 isoform X1. (1141 aa)
MCM4DNA helicase; Belongs to the MCM family. (860 aa)
ENSTSYP00000034042annotation not available (110 aa)
CDK2Cyclin-dependent kinase 2 isoform X1; Belongs to the protein kinase superfamily. (346 aa)
LOC110596262ubiquitin-40S ribosomal protein S27a-like. (156 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
ENSTSYP00000033058annotation not available (142 aa)
PSMC426S protease regulatory subunit 6B isoform X1; Belongs to the AAA ATPase family. (418 aa)
E2F6Transcription factor E2F6 isoform X2. (281 aa)
ENSTSYP00000032718annotation not available (175 aa)
PSME2Proteasome activator complex subunit 2 isoform X1. (254 aa)
ENSTSYP00000032262annotation not available (99 aa)
PSMB5Proteasome subunit beta. (263 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
ENSTSYP00000031721annotation not available (275 aa)
RPA3Replication protein A 14 kDa subunit. (121 aa)
AKT1Non-specific serine/threonine protein kinase. (393 aa)
LOC103262238Proteasome subunit alpha type. (261 aa)
ENSTSYP00000030901annotation not available (403 aa)
LOC103252110G2/mitotic-specific cyclin-B1 isoform X1; Belongs to the cyclin family. (433 aa)
PSMB8Proteasome subunit beta. (276 aa)
MYCMyc proto-oncogene protein. (376 aa)
ENSTSYP00000030676annotation not available (108 aa)
ENSTSYP00000030504annotation not available (156 aa)
LOC103265662DNA polymerase alpha subunit B. (391 aa)
MCM9DNA helicase MCM9; Belongs to the MCM family. (391 aa)
ENSTSYP00000029471annotation not available (82 aa)
LOC10325039226S protease regulatory subunit 7; Belongs to the AAA ATPase family. (400 aa)
ENSTSYP00000028770annotation not available (118 aa)
CDKN1BLOW QUALITY PROTEIN: cyclin-dependent kinase inhibitor 1B. (197 aa)
ENSTSYP00000028450annotation not available (227 aa)
ENSTSYP00000028373annotation not available (134 aa)
PSMC526S protease regulatory subunit 8 isoform X2; Belongs to the AAA ATPase family. (398 aa)
ENSTSYP00000027311annotation not available (388 aa)
CDKN1ACyclin-dependent kinase inhibitor 1. (164 aa)
ENSTSYP00000027147annotation not available (149 aa)
ENSTSYP00000027087annotation not available (52 aa)
LOC103272490DNA primase large subunit. (206 aa)
ENSTSYP00000026533annotation not available (256 aa)
PSMB10Proteasome subunit beta. (273 aa)
TYMSThymidylate synthase isoform X1. (313 aa)
PRIM2DNA primase large subunit. (159 aa)
MNAT1CDK-activating kinase assembly factor MAT1. (169 aa)
HDAC1Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (482 aa)
PSMD1326S proteasome non-ATPase regulatory subunit 13 isoform X1. (396 aa)
ENSTSYP00000025727annotation not available (215 aa)
PSMD926S proteasome non-ATPase regulatory subunit 9 isoform X1. (220 aa)
PSMD426S proteasome non-ATPase regulatory subunit 4 isoform X2. (377 aa)
LOC103254497lisH domain and HEAT repeat-containing protein KIAA1468-like. (391 aa)
ENSTSYP00000025346annotation not available (194 aa)
ENSTSYP00000024958annotation not available (55 aa)
ENSTSYP00000024947annotation not available (143 aa)
ENSTSYP00000024485annotation not available (234 aa)
ENSTSYP00000024219annotation not available (592 aa)
E2F1Transcription factor E2F1. (350 aa)
UBA52ubiquitin-60S ribosomal protein L40 isoform X1. (231 aa)
ENSTSYP00000023689annotation not available (139 aa)
ENSTSYP00000023430annotation not available (374 aa)
CCNE2G1/S-specific cyclin-E2 isoform X1; Belongs to the cyclin family. (404 aa)
LIN54Protein lin-54 homolog isoform X1. (749 aa)
CCND1G1/S-specific cyclin-D1. (156 aa)
ENSTSYP00000022222annotation not available (155 aa)
MCM3DNA helicase; Belongs to the MCM family. (853 aa)
ENSTSYP00000021540annotation not available (291 aa)
PSME3Proteasome activator complex subunit 3 isoform X1. (265 aa)
ENSTSYP00000021013annotation not available (135 aa)
ENSTSYP00000020949annotation not available (151 aa)
SKP2S-phase kinase-associated protein 2. (436 aa)
PSMB6Proteasome subunit beta. (242 aa)
CDK1Cyclin-dependent kinase 1 isoform X1; Belongs to the protein kinase superfamily. (297 aa)
PSMD1026S proteasome non-ATPase regulatory subunit 10 isoform X1. (226 aa)
ENSTSYP00000019245annotation not available (285 aa)
ENSTSYP00000019212annotation not available (259 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
ENSTSYP00000019039annotation not available (232 aa)
CABLES1CDK5 and ABL1 enzyme substrate 1. (367 aa)
CDT1DNA replication factor Cdt1. (468 aa)
KIAA2012LOW QUALITY PROTEIN: uncharacterized protein KIAA2012 homolog; Belongs to the eukaryotic ribosomal protein P1/P2 family. (1143 aa)
ENSTSYP00000017997annotation not available (123 aa)
PPP2R1ASerine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform isoform X1. (589 aa)
MEIOBLOW QUALITY PROTEIN: meiosis-specific with OB domain-containing protein. (470 aa)
ENSTSYP00000017776annotation not available (292 aa)
CDC45Cell division control protein 45 homolog isoform X1. (600 aa)
PPP2R1BSerine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform isoform X3. (667 aa)
PTK6Tyrosine-protein kinase. (450 aa)
ORC6Origin recognition complex subunit 6. (252 aa)
RPA4Replication protein A 30 kDa subunit. (261 aa)
ENSTSYP00000016214annotation not available (88 aa)
CUL1Cullin-1 isoform X1; Belongs to the cullin family. (776 aa)
PSMC326S protease regulatory subunit 6A; Belongs to the AAA ATPase family. (450 aa)
POLE3DNA polymerase epsilon subunit 3. (147 aa)
CDK3Cyclin-dependent kinase 3 isoform X1; Belongs to the protein kinase superfamily. (305 aa)
ENSTSYP00000015668annotation not available (251 aa)
ENSTSYP00000015529annotation not available (366 aa)
CDC25AM-phase inducer phosphatase 1 isoform X1. (523 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
CKS1BCyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa)
LIN37Protein lin-37 homolog isoform X2. (246 aa)
ENSTSYP00000014559annotation not available (115 aa)
PSMA6Proteasome subunit alpha type. (246 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
MAXProtein max isoform X1. (160 aa)
MCM5DNA replication licensing factor MCM5; Belongs to the MCM family. (598 aa)
POLE4DNA polymerase epsilon subunit 4. (117 aa)
CKS2Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa)
E2F5Transcription factor E2F5 isoform X1. (300 aa)
PPP2CBSerine/threonine-protein phosphatase. (309 aa)
ORC1Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (858 aa)
FNBP4Formin-binding protein 4 isoform X2. (669 aa)
PPP2R3ASerine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha isoform X1. (1142 aa)
PSMD1226S proteasome non-ATPase regulatory subunit 12. (420 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (623 aa)
PSMB3Proteasome subunit beta. (207 aa)
ORC5Origin recognition complex subunit 5. (309 aa)
PSMD326S proteasome non-ATPase regulatory subunit 3 isoform X2. (534 aa)
FBXO5F-box only protein 5 isoform X1. (447 aa)
PSMB7Proteasome subunit beta. (277 aa)
PSMD1126S proteasome non-ATPase regulatory subunit 11. (422 aa)
CDK4Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa)
PSMD626S proteasome non-ATPase regulatory subunit 6 isoform X1. (416 aa)
WEE1Wee1-like protein kinase. (432 aa)
CCNHcyclin-H; Belongs to the cyclin family. (232 aa)
GMNNGeminin isoform X1. (203 aa)
AKT3RAC-gamma serine/threonine-protein kinase; Belongs to the protein kinase superfamily. (419 aa)
PSMA7Proteasome endopeptidase complex. (248 aa)
PSMD526S proteasome non-ATPase regulatory subunit 5 isoform X1. (513 aa)
RPA2Replication protein A 32 kDa subunit. (231 aa)
SKP1S-phase kinase-associated protein 1 isoform X2; Belongs to the SKP1 family. (163 aa)
RRM2Ribonucleoside-diphosphate reductase subunit M2. (411 aa)
ENSTSYP00000009770annotation not available (227 aa)
PPP4R1Serine/threonine-protein phosphatase 4 regulatory subunit 1. (803 aa)
POLEDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2259 aa)
ORC2Origin recognition complex subunit 2 isoform X1. (574 aa)
RBL1Retinoblastoma-like protein 1. (1068 aa)
PSMC626S protease regulatory subunit 10B; Belongs to the AAA ATPase family. (403 aa)
PPP2R3CSerine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma isoform X3. (453 aa)
TK1Thymidine kinase. (267 aa)
TFDP2Transcription factor. (448 aa)
ENSTSYP00000008181annotation not available (412 aa)
CDK7Cyclin-dependent kinase 7 isoform X1. (332 aa)
LOC10327253526S proteasome non-ATPase regulatory subunit 7. (324 aa)
MCM10Protein MCM10 homolog isoform X1. (871 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
PSMC126S protease regulatory subunit 4; Belongs to the AAA ATPase family. (440 aa)
PSMB9Proteasome subunit beta. (219 aa)
E2F4Transcription factor E2F4. (407 aa)
CDC6Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (559 aa)
ORC4Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (435 aa)
ORC3Origin recognition complex subunit 3 isoform X2. (711 aa)
PRIM1DNA primase; Belongs to the eukaryotic-type primase small subunit family. (417 aa)
LIN9Protein lin-9 homolog isoform X1. (580 aa)
RELCHlisH domain and HEAT repeat-containing protein KIAA1468 homolog isoform X2. (721 aa)
MCM2DNA helicase; Belongs to the MCM family. (904 aa)
TM4SF19Transmembrane 4 L6 family member 19 isoform X2. (209 aa)
CCNA1cyclin-A1; Belongs to the cyclin family. (455 aa)
POLA1DNA polymerase alpha catalytic subunit. (988 aa)
PSMB2Proteasome subunit beta. (201 aa)
PSME1Proteasome activator complex subunit 1 isoform X1. (250 aa)
CDC7Cell division cycle 7-related protein kinase isoform X1. (574 aa)
PSMF1Proteasome inhibitor PI31 subunit isoform X2. (272 aa)
PSMA4Proteasome subunit alpha type. (179 aa)
CCNE1G1/S-specific cyclin-E1. (410 aa)
PSMD1426S proteasome non-ATPase regulatory subunit 14. (326 aa)
PPP4R4Serine/threonine-protein phosphatase 4 regulatory subunit 4 isoform X7. (809 aa)
MCM8DNA helicase MCM8; Belongs to the MCM family. (832 aa)
POLE2DNA polymerase epsilon subunit 2. (527 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa)
PSMA1Proteasome subunit alpha type. (264 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (617 aa)
MCM6DNA helicase; Belongs to the MCM family. (821 aa)
CCNA2cyclin-A2; Belongs to the cyclin family. (430 aa)
WEE2Wee1-like protein kinase. (567 aa)
LIN52Protein lin-52 homolog. (106 aa)
DBF4Protein DBF4 homolog A. (665 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (714 aa)
RB1Retinoblastoma-associated protein. (929 aa)
PSMB1Proteasome subunit beta. (241 aa)
RPS27Aubiquitin-40S ribosomal protein S27a. (156 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
ENSTSYP00000000614annotation not available (191 aa)
Your Current Organism:
Carlito syrichta
NCBI taxonomy Id: 1868482
Other names: C. syrichta, Philippine tarsier, Tarsius syrichta
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