STRINGSTRING
NRG2 NRG2 BTC BTC NRG4 NRG4 EREG EREG EGFR EGFR NRG3 NRG3 ERBB4 ERBB4 EGF EGF HBEGF HBEGF ERBB2 ERBB2 PTK6 PTK6 NRG1 NRG1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NRG2Pro-neuregulin-2, membrane-bound isoform. (243 aa)
BTCProbetacellulin. (178 aa)
NRG4Pro-neuregulin-4, membrane-bound isoform. (116 aa)
EREGProepiregulin. (167 aa)
EGFRReceptor protein-tyrosine kinase. (1180 aa)
NRG3Pro-neuregulin-3, membrane-bound isoform isoform X2. (344 aa)
ERBB4Receptor protein-tyrosine kinase. (1280 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1167 aa)
HBEGFProheparin-binding EGF-like growth factor. (209 aa)
ERBB2Receptor protein-tyrosine kinase. (1255 aa)
PTK6Tyrosine-protein kinase. (450 aa)
NRG1Pro-neuregulin-1, membrane-bound isoform isoform X3. (645 aa)
Your Current Organism:
Carlito syrichta
NCBI taxonomy Id: 1868482
Other names: C. syrichta, Philippine tarsier, Tarsius syrichta
Server load: low (38%) [HD]