35 items (Carlito syrichta) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ERBB2	Receptor protein-tyrosine kinase. (1255 aa)
	ENSTSYP00000014559	annotation not available (115 aa)
	AKT2	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
	ENSTSYP00000017997	annotation not available (123 aa)
	CDC37	Hsp90 co-chaperone Cdc37 isoform X2. (378 aa)
	ENSTSYP00000022222	annotation not available (155 aa)
	ENSTSYP00000022518	annotation not available (698 aa)
	RNF41	E3 ubiquitin-protein ligase NRDP1 isoform X1. (317 aa)
	UBA52	ubiquitin-60S ribosomal protein L40 isoform X1. (231 aa)
	LOC103275563	Receptor tyrosine-protein kinase erbB-3. (169 aa)
	ENSTSYP00000027147	annotation not available (149 aa)
	CUL5	Cullin-5; Belongs to the cullin family. (810 aa)
	NRG2	Pro-neuregulin-2, membrane-bound isoform. (243 aa)
	LOC110596262	ubiquitin-40S ribosomal protein S27a-like. (156 aa)
	ENSTSYP00000031842	annotation not available (607 aa)
	ERBIN	Erbin. (1420 aa)
	STUB1	E3 ubiquitin-protein ligase CHIP isoform X1. (299 aa)
	AKT1	Non-specific serine/threonine protein kinase. (393 aa)
	ENSTSYP00000030676	annotation not available (108 aa)
	NRG1	Pro-neuregulin-1, membrane-bound isoform isoform X3. (645 aa)
	ENSTSYP00000027808	annotation not available (611 aa)
	RPS27A	ubiquitin-40S ribosomal protein S27a. (156 aa)
	BTC	Probetacellulin. (178 aa)
	PTPN12	Tyrosine-protein phosphatase non-receptor type 12; Dephosphorylates a range of proteins, and thereby regulates cellular signaling cascades. (663 aa)
	NRG4	Pro-neuregulin-4, membrane-bound isoform. (116 aa)
	EREG	Proepiregulin. (167 aa)
	EGFR	Receptor protein-tyrosine kinase. (1180 aa)
	NRG3	Pro-neuregulin-3, membrane-bound isoform isoform X2. (344 aa)
	ERBB4	Receptor protein-tyrosine kinase. (1280 aa)
	PTPN18	Tyrosine-protein phosphatase non-receptor type 18. (454 aa)
	EGF	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1167 aa)
	USP8	Ubiquitin carboxyl-terminal hydrolase 8 isoform X1; Belongs to the peptidase C19 family. (1117 aa)
	AKT3	RAC-gamma serine/threonine-protein kinase; Belongs to the protein kinase superfamily. (419 aa)
	HBEGF	Proheparin-binding EGF-like growth factor. (209 aa)
	HSP90AA1	Heat shock protein HSP 90-alpha. (813 aa)

Your Current Organism:

Carlito syrichta

NCBI taxonomy Id: 1868482
Other names: C. syrichta, Philippine tarsier, Tarsius syrichta

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKT1	AKT2	ENSTSYP00000030955	ENSTSYP00000014890	Non-specific serine/threonine protein kinase.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.975
AKT1	AKT3	ENSTSYP00000030955	ENSTSYP00000010131	Non-specific serine/threonine protein kinase.	RAC-gamma serine/threonine-protein kinase; Belongs to the protein kinase superfamily.	0.910
AKT1	CDC37	ENSTSYP00000030955	ENSTSYP00000021862	Non-specific serine/threonine protein kinase.	Hsp90 co-chaperone Cdc37 isoform X2.	0.971
AKT1	EGF	ENSTSYP00000030955	ENSTSYP00000008584	Non-specific serine/threonine protein kinase.	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	0.628
AKT1	EGFR	ENSTSYP00000030955	ENSTSYP00000005737	Non-specific serine/threonine protein kinase.	Receptor protein-tyrosine kinase.	0.689
AKT1	ENSTSYP00000014559	ENSTSYP00000030955	ENSTSYP00000014559	Non-specific serine/threonine protein kinase.	annotation not available	0.438
AKT1	ENSTSYP00000017997	ENSTSYP00000030955	ENSTSYP00000017997	Non-specific serine/threonine protein kinase.	annotation not available	0.412
AKT1	ENSTSYP00000022518	ENSTSYP00000030955	ENSTSYP00000022518	Non-specific serine/threonine protein kinase.	annotation not available	0.947
AKT1	ENSTSYP00000027808	ENSTSYP00000030955	ENSTSYP00000027808	Non-specific serine/threonine protein kinase.	annotation not available	0.947
AKT1	ENSTSYP00000030676	ENSTSYP00000030955	ENSTSYP00000030676	Non-specific serine/threonine protein kinase.	annotation not available	0.412
AKT1	ENSTSYP00000031842	ENSTSYP00000030955	ENSTSYP00000031842	Non-specific serine/threonine protein kinase.	annotation not available	0.947
AKT1	ERBB2	ENSTSYP00000030955	ENSTSYP00000014181	Non-specific serine/threonine protein kinase.	Receptor protein-tyrosine kinase.	0.514
AKT1	ERBB4	ENSTSYP00000030955	ENSTSYP00000006840	Non-specific serine/threonine protein kinase.	Receptor protein-tyrosine kinase.	0.569
AKT1	HSP90AA1	ENSTSYP00000030955	ENSTSYP00000010941	Non-specific serine/threonine protein kinase.	Heat shock protein HSP 90-alpha.	0.947
AKT1	LOC103275563	ENSTSYP00000030955	ENSTSYP00000024668	Non-specific serine/threonine protein kinase.	Receptor tyrosine-protein kinase erbB-3.	0.491
AKT1	NRG1	ENSTSYP00000030955	ENSTSYP00000027811	Non-specific serine/threonine protein kinase.	Pro-neuregulin-1, membrane-bound isoform isoform X3.	0.489
AKT1	RNF41	ENSTSYP00000030955	ENSTSYP00000022689	Non-specific serine/threonine protein kinase.	E3 ubiquitin-protein ligase NRDP1 isoform X1.	0.446
AKT1	STUB1	ENSTSYP00000030955	ENSTSYP00000031838	Non-specific serine/threonine protein kinase.	E3 ubiquitin-protein ligase CHIP isoform X1.	0.681
AKT1	UBA52	ENSTSYP00000030955	ENSTSYP00000023912	Non-specific serine/threonine protein kinase.	ubiquitin-60S ribosomal protein L40 isoform X1.	0.412
AKT1	USP8	ENSTSYP00000030955	ENSTSYP00000009433	Non-specific serine/threonine protein kinase.	Ubiquitin carboxyl-terminal hydrolase 8 isoform X1; Belongs to the peptidase C19 family.	0.720