STRINGSTRING
ADK ADK PNP PNP UPP1 UPP1 UCK2 UCK2 TK1 TK1 PRTFDC1 PRTFDC1 GMPR GMPR ENKUR ENKUR DCK DCK DGUOK DGUOK ADA ADA TK2 TK2 AMPD1 AMPD1 APRT APRT UCK1 UCK1 AMPD3 AMPD3 PUDP PUDP AMPD2 AMPD2 ENSTSYP00000027795 ENSTSYP00000027795 GMPR2 GMPR2 HPRT1 HPRT1 UCKL1 UCKL1 CDA CDA ADAL ADAL
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ADKAdenosine kinase. (271 aa)
PNPPurine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (289 aa)
UPP1Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. (310 aa)
UCK2Uridine-cytidine kinase 2. (224 aa)
TK1Thymidine kinase. (267 aa)
PRTFDC1Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (208 aa)
GMPRGMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. (345 aa)
ENKUREnkurin. (256 aa)
DCKDeoxycytidine kinase. (169 aa)
DGUOKDeoxyguanosine kinase, mitochondrial isoform X1. (277 aa)
ADAAdenosine deaminase. (363 aa)
TK2Thymidine kinase 2, mitochondrial isoform X5. (278 aa)
AMPD1LOW QUALITY PROTEIN: AMP deaminase 1. (428 aa)
APRTAdenine phosphoribosyltransferase. (164 aa)
UCK1Uridine-cytidine kinase 1 isoform X1. (282 aa)
AMPD3AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (777 aa)
PUDPPseudouridine-5'-phosphatase. (233 aa)
AMPD2AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (858 aa)
ENSTSYP00000027795annotation not available (290 aa)
GMPR2GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. (396 aa)
HPRT1Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (219 aa)
UCKL1Uridine-cytidine kinase; Belongs to the uridine kinase family. (520 aa)
CDACytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (145 aa)
ADALAdenosine deaminase-like protein. (357 aa)
Your Current Organism:
Carlito syrichta
NCBI taxonomy Id: 1868482
Other names: C. syrichta, Philippine tarsier, Tarsius syrichta
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