STRINGSTRING
PDPK1 PDPK1 ZDHHC21 ZDHHC21 CREB1 CREB1 LOC110594775 LOC110594775 MMP3 MMP3 ENSTSYP00000000513 ENSTSYP00000000513 STRN3 STRN3 SPHK1 SPHK1 BTC BTC MMP2 MMP2 MMP9 MMP9 IGF1R IGF1R GNGT1 GNGT1 HRAS HRAS CSDE1 CSDE1 PIK3CA PIK3CA KRAS KRAS EREG EREG EGFR EGFR ESR1 ESR1 SRF SRF AKT2 AKT2 LOC110595842 LOC110595842 GNB1 GNB1 ESR2 ESR2 WDR64 WDR64 XPO1 XPO1 PRMT1 PRMT1 PIK3R1 PIK3R1 STRN4 STRN4 TGFA TGFA PRMT8 PRMT8 UHMK1 UHMK1 PRKCZ PRKCZ ENSTSYP00000022518 ENSTSYP00000022518 CCND1 CCND1 GNG3 GNG3 GNB4 GNB4 ENSTSYP00000024385 ENSTSYP00000024385 GNG7 GNG7 GNG4 GNG4 NRAS NRAS PTK2 PTK2 PIK3R3 PIK3R3 NOS3 NOS3 ENSTSYP00000026316 ENSTSYP00000026316 ENSTSYP00000027808 ENSTSYP00000027808 MAPK3 MAPK3 ZDHHC7 ZDHHC7 CDKN1B CDKN1B GNGT2 GNGT2 GNG13 GNG13 FOS FOS GNG11 GNG11 EPGN EPGN GNAI1 GNAI1 AKT1 AKT1 GNG12 GNG12 ENSTSYP00000031842 ENSTSYP00000031842 MAPK1 MAPK1 CAV1 CAV1 GNB2 GNB2 GNAI3 GNAI3 GNAI2 GNAI2 ENSTSYP00000032761 ENSTSYP00000032761 SRC SRC GNB3 GNB3 ELK1 ELK1 CAV2 CAV2 GNG2 GNG2 EGF EGF ENSTSYP00000009157 ENSTSYP00000009157 AREG AREG STRN STRN AKT3 AKT3 SHC1 SHC1 HBEGF HBEGF GNAT3 GNAT3 HSP90AA1 HSP90AA1 MMP7 MMP7 GNB5 GNB5 LOC103266246 LOC103266246
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PDPK13-phosphoinositide-dependent protein kinase 1. (554 aa)
ZDHHC21Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (265 aa)
CREB1Cyclic AMP-responsive element-binding protein 1 isoform X1. (341 aa)
LOC110594775Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
MMP3Stromelysin-1. (477 aa)
ENSTSYP00000000513annotation not available (297 aa)
STRN3Striatin-3 isoform X1. (797 aa)
SPHK1Sphingosine kinase 1. (438 aa)
BTCProbetacellulin. (178 aa)
MMP272 kDa type IV collagenase. (662 aa)
MMP9Matrix metalloproteinase-9. (710 aa)
IGF1RTyrosine-protein kinase receptor. (1335 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
HRASGTPase HRas isoform X6. (189 aa)
CSDE1Cold shock domain-containing protein E1 isoform X1. (842 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
KRASGTPase KRas isoform X1. (189 aa)
EREGProepiregulin. (167 aa)
EGFRReceptor protein-tyrosine kinase. (1180 aa)
ESR1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (589 aa)
SRFSerum response factor isoform X1. (456 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
LOC110595842Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (63 aa)
GNB1Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 isoform X1. (340 aa)
ESR2Estrogen receptor beta isoform X1. (530 aa)
WDR64WD repeat-containing protein 64. (359 aa)
XPO1Exportin-1. (1071 aa)
PRMT1Protein arginine N-methyltransferase 1 isoform X1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (371 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (612 aa)
STRN4Striatin-4 isoform X1. (760 aa)
TGFATransforming growth factor alpha. (164 aa)
PRMT8Protein arginine N-methyltransferase 8; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (369 aa)
UHMK1Serine/threonine-protein kinase Kist isoform X1. (460 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (558 aa)
ENSTSYP00000022518annotation not available (698 aa)
CCND1G1/S-specific cyclin-D1. (156 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
GNB4Guanine nucleotide-binding protein subunit beta-4. (340 aa)
ENSTSYP00000024385annotation not available (65 aa)
GNG7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
NRASGTPase NRas. (189 aa)
PTK2Focal adhesion kinase 1 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1096 aa)
PIK3R3Phosphatidylinositol 3-kinase regulatory subunit gamma isoform X2. (461 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1209 aa)
ENSTSYP00000026316annotation not available (161 aa)
ENSTSYP00000027808annotation not available (611 aa)
MAPK3Mitogen-activated protein kinase. (363 aa)
ZDHHC7Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (340 aa)
CDKN1BLOW QUALITY PROTEIN: cyclin-dependent kinase inhibitor 1B. (197 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
GNG13Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13. (67 aa)
FOSProto-oncogene c-Fos. (379 aa)
GNG11Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
EPGNEpigen isoform X1. (153 aa)
GNAI1Guanine nucleotide-binding protein G(I) subunit alpha-1. (354 aa)
AKT1Non-specific serine/threonine protein kinase. (393 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
ENSTSYP00000031842annotation not available (607 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (363 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
GNB2Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 isoform X3. (321 aa)
GNAI3Guanine nucleotide-binding protein G(K) subunit alpha. (354 aa)
GNAI2Guanine nucleotide-binding protein G(I) subunit alpha-2 isoform X1. (355 aa)
ENSTSYP00000032761annotation not available (68 aa)
SRCTyrosine-protein kinase. (542 aa)
GNB3Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 isoform X1. (340 aa)
ELK1ETS domain-containing protein Elk-1 isoform X1. (430 aa)
CAV2Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (162 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (107 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1167 aa)
ENSTSYP00000009157annotation not available (65 aa)
AREGAmphiregulin isoform X1. (270 aa)
STRNStriatin isoform X1. (780 aa)
AKT3RAC-gamma serine/threonine-protein kinase; Belongs to the protein kinase superfamily. (419 aa)
SHC1SHC-transforming protein 1 isoform X1. (474 aa)
HBEGFProheparin-binding EGF-like growth factor. (209 aa)
GNAT3Guanine nucleotide-binding protein G(T) subunit alpha-3 isoform X1. (354 aa)
HSP90AA1Heat shock protein HSP 90-alpha. (813 aa)
MMP7Matrilysin. (267 aa)
GNB5Guanine nucleotide-binding protein subunit beta-5. (396 aa)
LOC103266246WD repeat-containing protein 64-like. (276 aa)
Your Current Organism:
Carlito syrichta
NCBI taxonomy Id: 1868482
Other names: C. syrichta, Philippine tarsier, Tarsius syrichta
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