53 items (Carlito syrichta) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DLL1	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (741 aa)
	MAML1	Mastermind-like protein 1. (865 aa)
	ENSTSYP00000013724	annotation not available (262 aa)
	NOTCH3	Neurogenic locus notch homolog protein 3. (2169 aa)
	PBX1	pre-B-cell leukemia transcription factor 1. (342 aa)
	PBX3	pre-B-cell leukemia transcription factor 3. (342 aa)
	DLL4	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (685 aa)
	APH1B	Gamma-secretase subunit APH-1B. (245 aa)
	EGF	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1167 aa)
	YBX1	Nuclease-sensitive element-binding protein 1. (291 aa)
	KAT2B	Histone acetyltransferase KAT2B. (731 aa)
	EGFR	Receptor protein-tyrosine kinase. (1180 aa)
	PSENEN	Gamma-secretase subunit PEN-2. (101 aa)
	ADAM10	Disintegrin and metalloproteinase domain-containing protein 10. (679 aa)
	JAG1	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1214 aa)
	EP300	Histone acetyltransferase p300. (2174 aa)
	RPS27A	ubiquitin-40S ribosomal protein S27a. (156 aa)
	FABP7	Fatty acid-binding protein, brain; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (132 aa)
	JAG2	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1101 aa)
	TACC3	Transforming acidic coiled-coil-containing protein 3. (65 aa)
	PTCRA	Pre T-cell antigen receptor alpha. (259 aa)
	SNW1	SNW domain-containing protein 1 isoform X2. (536 aa)
	RBPJ	Recombining binding protein suppressor of hairless isoform X1. (529 aa)
	APH1A	Gamma-secretase subunit APH-1A isoform X1. (265 aa)
	ENSTSYP00000029157	annotation not available (359 aa)
	HES1	Transcription factor HES-1. (272 aa)
	HEY1	Hairy/enhancer-of-split related with YRPW motif protein 1 isoform X2. (304 aa)
	PBX4	pre-B-cell leukemia transcription factor 4. (362 aa)
	ENSTSYP00000024826	annotation not available (506 aa)
	WWP2	E3 ubiquitin-protein ligase. (869 aa)
	KAT2A	Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (798 aa)
	LOC110595233	pre-B-cell leukemia transcription factor 3-like isoform X1. (113 aa)
	UBA52	ubiquitin-60S ribosomal protein L40 isoform X1. (231 aa)
	NCSTN	Nicastrin isoform X1. (708 aa)
	ENSTSYP00000023565	annotation not available (292 aa)
	ENSTSYP00000022222	annotation not available (155 aa)
	MAMLD1	Mastermind-like domain-containing protein 1. (798 aa)
	ENSTSYP00000020409	annotation not available (369 aa)
	LOC103267797	pre-B-cell leukemia transcription factor 1-like. (100 aa)
	PSEN2	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (481 aa)
	MIB1	E3 ubiquitin-protein ligase MIB1. (1006 aa)
	ENSTSYP00000018602	annotation not available (632 aa)
	PBX2	pre-B-cell leukemia transcription factor 2 isoform X2. (430 aa)
	DLGAP5	Disks large-associated protein 5. (839 aa)
	ENSTSYP00000014053	annotation not available (476 aa)
	LOC110596262	ubiquitin-40S ribosomal protein S27a-like. (156 aa)
	NEURL1B	E3 ubiquitin-protein ligase NEURL1B. (315 aa)
	MIB2	E3 ubiquitin-protein ligase MIB2. (986 aa)
	NOTCH1	Neurogenic locus notch homolog protein 1. (2339 aa)
	CREBBP	CREB-binding protein isoform X1. (2433 aa)
	HEYL	Hairy/enhancer-of-split related with YRPW motif-like protein isoform X1. (328 aa)
	IKZF1	DNA-binding protein Ikaros. (515 aa)
	PSEN1	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa)

Your Current Organism:

Carlito syrichta

NCBI taxonomy Id: 1868482
Other names: C. syrichta, Philippine tarsier, Tarsius syrichta

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADAM10	APH1A	ENSTSYP00000002825	ENSTSYP00000030221	Disintegrin and metalloproteinase domain-containing protein 10.	Gamma-secretase subunit APH-1A isoform X1.	0.551
ADAM10	APH1B	ENSTSYP00000002825	ENSTSYP00000008833	Disintegrin and metalloproteinase domain-containing protein 10.	Gamma-secretase subunit APH-1B.	0.459
ADAM10	DLL1	ENSTSYP00000002825	ENSTSYP00000005404	Disintegrin and metalloproteinase domain-containing protein 10.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.788
ADAM10	DLL4	ENSTSYP00000002825	ENSTSYP00000011135	Disintegrin and metalloproteinase domain-containing protein 10.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.690
ADAM10	EGF	ENSTSYP00000002825	ENSTSYP00000008584	Disintegrin and metalloproteinase domain-containing protein 10.	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	0.558
ADAM10	JAG1	ENSTSYP00000002825	ENSTSYP00000002804	Disintegrin and metalloproteinase domain-containing protein 10.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.672
ADAM10	JAG2	ENSTSYP00000002825	ENSTSYP00000032111	Disintegrin and metalloproteinase domain-containing protein 10.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.672
ADAM10	NCSTN	ENSTSYP00000002825	ENSTSYP00000023582	Disintegrin and metalloproteinase domain-containing protein 10.	Nicastrin isoform X1.	0.656
ADAM10	NOTCH1	ENSTSYP00000002825	ENSTSYP00000033056	Disintegrin and metalloproteinase domain-containing protein 10.	Neurogenic locus notch homolog protein 1.	0.818
ADAM10	NOTCH3	ENSTSYP00000002825	ENSTSYP00000011625	Disintegrin and metalloproteinase domain-containing protein 10.	Neurogenic locus notch homolog protein 3.	0.620
ADAM10	PSEN1	ENSTSYP00000002825	ENSTSYP00000032237	Disintegrin and metalloproteinase domain-containing protein 10.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.613
ADAM10	PSEN2	ENSTSYP00000002825	ENSTSYP00000018767	Disintegrin and metalloproteinase domain-containing protein 10.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.574
ADAM10	PSENEN	ENSTSYP00000002825	ENSTSYP00000014007	Disintegrin and metalloproteinase domain-containing protein 10.	Gamma-secretase subunit PEN-2.	0.652
APH1A	ADAM10	ENSTSYP00000030221	ENSTSYP00000002825	Gamma-secretase subunit APH-1A isoform X1.	Disintegrin and metalloproteinase domain-containing protein 10.	0.551
APH1A	APH1B	ENSTSYP00000030221	ENSTSYP00000008833	Gamma-secretase subunit APH-1A isoform X1.	Gamma-secretase subunit APH-1B.	0.891
APH1A	DLL1	ENSTSYP00000030221	ENSTSYP00000005404	Gamma-secretase subunit APH-1A isoform X1.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.518
APH1A	DLL4	ENSTSYP00000030221	ENSTSYP00000011135	Gamma-secretase subunit APH-1A isoform X1.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.509
APH1A	JAG1	ENSTSYP00000030221	ENSTSYP00000002804	Gamma-secretase subunit APH-1A isoform X1.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.541
APH1A	JAG2	ENSTSYP00000030221	ENSTSYP00000032111	Gamma-secretase subunit APH-1A isoform X1.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.521
APH1A	NCSTN	ENSTSYP00000030221	ENSTSYP00000023582	Gamma-secretase subunit APH-1A isoform X1.	Nicastrin isoform X1.	0.999