STRINGSTRING
DLL1 DLL1 MAML1 MAML1 ENSTSYP00000013724 ENSTSYP00000013724 NOTCH3 NOTCH3 PBX1 PBX1 PBX3 PBX3 DLL4 DLL4 APH1B APH1B EGF EGF YBX1 YBX1 KAT2B KAT2B EGFR EGFR PSENEN PSENEN ADAM10 ADAM10 JAG1 JAG1 EP300 EP300 RPS27A RPS27A FABP7 FABP7 JAG2 JAG2 TACC3 TACC3 PTCRA PTCRA SNW1 SNW1 RBPJ RBPJ APH1A APH1A ENSTSYP00000029157 ENSTSYP00000029157 HES1 HES1 HEY1 HEY1 PBX4 PBX4 ENSTSYP00000024826 ENSTSYP00000024826 WWP2 WWP2 KAT2A KAT2A LOC110595233 LOC110595233 UBA52 UBA52 NCSTN NCSTN ENSTSYP00000023565 ENSTSYP00000023565 ENSTSYP00000022222 ENSTSYP00000022222 MAMLD1 MAMLD1 ENSTSYP00000020409 ENSTSYP00000020409 LOC103267797 LOC103267797 PSEN2 PSEN2 MIB1 MIB1 ENSTSYP00000018602 ENSTSYP00000018602 PBX2 PBX2 DLGAP5 DLGAP5 ENSTSYP00000014053 ENSTSYP00000014053 LOC110596262 LOC110596262 NEURL1B NEURL1B MIB2 MIB2 NOTCH1 NOTCH1 CREBBP CREBBP HEYL HEYL IKZF1 IKZF1 PSEN1 PSEN1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (741 aa)
MAML1Mastermind-like protein 1. (865 aa)
ENSTSYP00000013724annotation not available (262 aa)
NOTCH3Neurogenic locus notch homolog protein 3. (2169 aa)
PBX1pre-B-cell leukemia transcription factor 1. (342 aa)
PBX3pre-B-cell leukemia transcription factor 3. (342 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (685 aa)
APH1BGamma-secretase subunit APH-1B. (245 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1167 aa)
YBX1Nuclease-sensitive element-binding protein 1. (291 aa)
KAT2BHistone acetyltransferase KAT2B. (731 aa)
EGFRReceptor protein-tyrosine kinase. (1180 aa)
PSENENGamma-secretase subunit PEN-2. (101 aa)
ADAM10Disintegrin and metalloproteinase domain-containing protein 10. (679 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1214 aa)
EP300Histone acetyltransferase p300. (2174 aa)
RPS27Aubiquitin-40S ribosomal protein S27a. (156 aa)
FABP7Fatty acid-binding protein, brain; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (132 aa)
JAG2Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1101 aa)
TACC3Transforming acidic coiled-coil-containing protein 3. (65 aa)
PTCRAPre T-cell antigen receptor alpha. (259 aa)
SNW1SNW domain-containing protein 1 isoform X2. (536 aa)
RBPJRecombining binding protein suppressor of hairless isoform X1. (529 aa)
APH1AGamma-secretase subunit APH-1A isoform X1. (265 aa)
ENSTSYP00000029157annotation not available (359 aa)
HES1Transcription factor HES-1. (272 aa)
HEY1Hairy/enhancer-of-split related with YRPW motif protein 1 isoform X2. (304 aa)
PBX4pre-B-cell leukemia transcription factor 4. (362 aa)
ENSTSYP00000024826annotation not available (506 aa)
WWP2E3 ubiquitin-protein ligase. (869 aa)
KAT2AHistone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (798 aa)
LOC110595233pre-B-cell leukemia transcription factor 3-like isoform X1. (113 aa)
UBA52ubiquitin-60S ribosomal protein L40 isoform X1. (231 aa)
NCSTNNicastrin isoform X1. (708 aa)
ENSTSYP00000023565annotation not available (292 aa)
ENSTSYP00000022222annotation not available (155 aa)
MAMLD1Mastermind-like domain-containing protein 1. (798 aa)
ENSTSYP00000020409annotation not available (369 aa)
LOC103267797pre-B-cell leukemia transcription factor 1-like. (100 aa)
PSEN2Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (481 aa)
MIB1E3 ubiquitin-protein ligase MIB1. (1006 aa)
ENSTSYP00000018602annotation not available (632 aa)
PBX2pre-B-cell leukemia transcription factor 2 isoform X2. (430 aa)
DLGAP5Disks large-associated protein 5. (839 aa)
ENSTSYP00000014053annotation not available (476 aa)
LOC110596262ubiquitin-40S ribosomal protein S27a-like. (156 aa)
NEURL1BE3 ubiquitin-protein ligase NEURL1B. (315 aa)
MIB2E3 ubiquitin-protein ligase MIB2. (986 aa)
NOTCH1Neurogenic locus notch homolog protein 1. (2339 aa)
CREBBPCREB-binding protein isoform X1. (2433 aa)
HEYLHairy/enhancer-of-split related with YRPW motif-like protein isoform X1. (328 aa)
IKZF1DNA-binding protein Ikaros. (515 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa)
Your Current Organism:
Carlito syrichta
NCBI taxonomy Id: 1868482
Other names: C. syrichta, Philippine tarsier, Tarsius syrichta
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