22 items (Carlito syrichta) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	EREG	Proepiregulin. (167 aa)
	BTC	Probetacellulin. (178 aa)
	EGF	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1167 aa)
	ELK1	ETS domain-containing protein Elk-1 isoform X1. (430 aa)
	CREB1	Cyclic AMP-responsive element-binding protein 1 isoform X1. (341 aa)
	EGFR	Receptor protein-tyrosine kinase. (1180 aa)
	AREG	Amphiregulin isoform X1. (270 aa)
	AKT3	RAC-gamma serine/threonine-protein kinase; Belongs to the protein kinase superfamily. (419 aa)
	HBEGF	Proheparin-binding EGF-like growth factor. (209 aa)
	SRF	Serum response factor isoform X1. (456 aa)
	AKT2	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
	XPO1	Exportin-1. (1071 aa)
	TGFA	Transforming growth factor alpha. (164 aa)
	UHMK1	Serine/threonine-protein kinase Kist isoform X1. (460 aa)
	CCND1	G1/S-specific cyclin-D1. (156 aa)
	PTK2	Focal adhesion kinase 1 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1096 aa)
	MAPK3	Mitogen-activated protein kinase. (363 aa)
	CDKN1B	LOW QUALITY PROTEIN: cyclin-dependent kinase inhibitor 1B. (197 aa)
	FOS	Proto-oncogene c-Fos. (379 aa)
	EPGN	Epigen isoform X1. (153 aa)
	AKT1	Non-specific serine/threonine protein kinase. (393 aa)
	MAPK1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (363 aa)

Your Current Organism:

Carlito syrichta

NCBI taxonomy Id: 1868482
Other names: C. syrichta, Philippine tarsier, Tarsius syrichta

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKT1	AKT2	ENSTSYP00000030955	ENSTSYP00000014890	Non-specific serine/threonine protein kinase.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.975
AKT1	AKT3	ENSTSYP00000030955	ENSTSYP00000010131	Non-specific serine/threonine protein kinase.	RAC-gamma serine/threonine-protein kinase; Belongs to the protein kinase superfamily.	0.910
AKT1	CCND1	ENSTSYP00000030955	ENSTSYP00000022614	Non-specific serine/threonine protein kinase.	G1/S-specific cyclin-D1.	0.671
AKT1	CDKN1B	ENSTSYP00000030955	ENSTSYP00000028621	Non-specific serine/threonine protein kinase.	LOW QUALITY PROTEIN: cyclin-dependent kinase inhibitor 1B.	0.981
AKT1	CREB1	ENSTSYP00000030955	ENSTSYP00000006351	Non-specific serine/threonine protein kinase.	Cyclic AMP-responsive element-binding protein 1 isoform X1.	0.932
AKT1	EGF	ENSTSYP00000030955	ENSTSYP00000008584	Non-specific serine/threonine protein kinase.	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	0.628
AKT1	EGFR	ENSTSYP00000030955	ENSTSYP00000005737	Non-specific serine/threonine protein kinase.	Receptor protein-tyrosine kinase.	0.689
AKT1	FOS	ENSTSYP00000030955	ENSTSYP00000029847	Non-specific serine/threonine protein kinase.	Proto-oncogene c-Fos.	0.675
AKT1	MAPK1	ENSTSYP00000030955	ENSTSYP00000032180	Non-specific serine/threonine protein kinase.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.945
AKT1	MAPK3	ENSTSYP00000030955	ENSTSYP00000027878	Non-specific serine/threonine protein kinase.	Mitogen-activated protein kinase.	0.920
AKT1	PTK2	ENSTSYP00000030955	ENSTSYP00000025302	Non-specific serine/threonine protein kinase.	Focal adhesion kinase 1 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.784
AKT1	SRF	ENSTSYP00000030955	ENSTSYP00000014821	Non-specific serine/threonine protein kinase.	Serum response factor isoform X1.	0.528
AKT1	TGFA	ENSTSYP00000030955	ENSTSYP00000021904	Non-specific serine/threonine protein kinase.	Transforming growth factor alpha.	0.557
AKT2	AKT1	ENSTSYP00000014890	ENSTSYP00000030955	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase.	0.975
AKT2	AKT3	ENSTSYP00000014890	ENSTSYP00000010131	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	RAC-gamma serine/threonine-protein kinase; Belongs to the protein kinase superfamily.	0.879
AKT2	CCND1	ENSTSYP00000014890	ENSTSYP00000022614	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	G1/S-specific cyclin-D1.	0.500
AKT2	CDKN1B	ENSTSYP00000014890	ENSTSYP00000028621	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	LOW QUALITY PROTEIN: cyclin-dependent kinase inhibitor 1B.	0.930
AKT2	CREB1	ENSTSYP00000014890	ENSTSYP00000006351	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Cyclic AMP-responsive element-binding protein 1 isoform X1.	0.890
AKT2	EGFR	ENSTSYP00000014890	ENSTSYP00000005737	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Receptor protein-tyrosine kinase.	0.624
AKT2	FOS	ENSTSYP00000014890	ENSTSYP00000029847	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Proto-oncogene c-Fos.	0.565