STRINGSTRING
ENSTSYP00000033658 ENSTSYP00000033658 NFE2L2 NFE2L2 SPATA5L1 SPATA5L1 ENSTSYP00000000614 ENSTSYP00000000614 PSMA5 PSMA5 RPS27A RPS27A EP300 EP300 PSMB1 PSMB1 PSMA1 PSMA1 PSMD2 PSMD2 FBXL17 FBXL17 SESN1 SESN1 SPATA5 SPATA5 TRIM58 TRIM58 GCLM GCLM PSMD14 PSMD14 PSMA4 PSMA4 SLC7A11 SLC7A11 PSMF1 PSMF1 PSME1 PSME1 PSMB2 PSMB2 LOC103254447 LOC103254447 PSMA8 PSMA8 IDH1 IDH1 TKT TKT PGD PGD SRXN1 SRXN1 CUL3 CUL3 PRKCD PRKCD PSMB9 PSMB9 PSMC1 PSMC1 PSMB4 PSMB4 LOC103272535 LOC103272535 VCP VCP PSMC6 PSMC6 ENSTSYP00000009770 ENSTSYP00000009770 BACH1 BACH1 SKP1 SKP1 PSMD5 PSMD5 KLHL18 KLHL18 ME1 ME1 PSMA7 PSMA7 PRDX1 PRDX1 AKT3 AKT3 TXNRD1 TXNRD1 PSMD6 PSMD6 CSNK2A2 CSNK2A2 PSME4 PSME4 TRIM21 TRIM21 PSMD11 PSMD11 PSMB7 PSMB7 PSMD3 PSMD3 PSMB3 PSMB3 PSMD1 PSMD1 PSMD12 PSMD12 PALB2 PALB2 UFD1 UFD1 SQSTM1 SQSTM1 SESN2 SESN2 PSMA6 PSMA6 ENSTSYP00000014559 ENSTSYP00000014559 AKT2 AKT2 GSK3B GSK3B ENSTSYP00000015668 ENSTSYP00000015668 PSMC3 PSMC3 CUL1 CUL1 LY6G5B LY6G5B CSNK2A1 CSNK2A1 MAP1LC3B MAP1LC3B LOC103251634 LOC103251634 ENSTSYP00000017997 ENSTSYP00000017997 KIAA2012 KIAA2012 GSR GSR ENSTSYP00000019039 ENSTSYP00000019039 ENSTSYP00000019245 ENSTSYP00000019245 PSMD10 PSMD10 RBX1 RBX1 PSMB6 PSMB6 SKP2 SKP2 ENSTSYP00000020999 ENSTSYP00000020999 ENSTSYP00000021013 ENSTSYP00000021013 PSME3 PSME3 ENSTSYP00000021540 ENSTSYP00000021540 BTRC BTRC ENSTSYP00000022222 ENSTSYP00000022222 BACH2 BACH2 NPLOC4 NPLOC4 ENSTSYP00000023689 ENSTSYP00000023689 KLHL17 KLHL17 UBA52 UBA52 MUL1 MUL1 ENSTSYP00000024458 ENSTSYP00000024458 ENSTSYP00000024485 ENSTSYP00000024485 ENSTSYP00000024947 ENSTSYP00000024947 ENSTSYP00000025007 ENSTSYP00000025007 KEAP1 KEAP1 ENSTSYP00000025346 ENSTSYP00000025346 PSMD4 PSMD4 PSMD9 PSMD9 ENSTSYP00000025727 ENSTSYP00000025727 PSMD13 PSMD13 UBXN7 UBXN7 PSMB10 PSMB10 HMOX1 HMOX1 ENSTSYP00000027147 ENSTSYP00000027147 CDKN1A CDKN1A ENSTSYP00000027311 ENSTSYP00000027311 PSMC5 PSMC5 CSNK2B CSNK2B G6PD G6PD ENSTSYP00000028029 ENSTSYP00000028029 ENSTSYP00000028373 ENSTSYP00000028373 ENSTSYP00000028450 ENSTSYP00000028450 ENSTSYP00000028770 ENSTSYP00000028770 LOC103250392 LOC103250392 GCLC GCLC ENSTSYP00000030504 ENSTSYP00000030504 TXNRD3 TXNRD3 ENSTSYP00000030676 ENSTSYP00000030676 MYC MYC PSMB8 PSMB8 ENSTSYP00000030893 ENSTSYP00000030893 LOC103262238 LOC103262238 AKT1 AKT1 MTFP1 MTFP1 BRCA1 BRCA1 ENSTSYP00000031721 ENSTSYP00000031721 PSMA2 PSMA2 PSMB5 PSMB5 NQO1 NQO1 ENSTSYP00000032262 ENSTSYP00000032262 TALDO1 TALDO1 PSME2 PSME2 ENSTSYP00000032718 ENSTSYP00000032718 PSMC4 PSMC4 CREBBP CREBBP NOTCH1 NOTCH1 ENSTSYP00000033058 ENSTSYP00000033058 PSMA3 PSMA3 LOC110596262 LOC110596262 ATF4 ATF4 ENSTSYP00000033562 ENSTSYP00000033562 LOC103252213 LOC103252213 ENSTSYP00000033656 ENSTSYP00000033656 AMER1 AMER1 ENSTSYP00000034030 ENSTSYP00000034030 ENSTSYP00000034042 ENSTSYP00000034042 DPP3 DPP3 PSMD8 PSMD8 MAFG MAFG NFE2L1 NFE2L1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSTSYP00000033658annotation not available (79 aa)
NFE2L2Nuclear factor erythroid 2-related factor 2 isoform X1. (591 aa)
SPATA5L1Spermatogenesis-associated protein 5-like protein 1 isoform X2. (751 aa)
ENSTSYP00000000614annotation not available (191 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
RPS27Aubiquitin-40S ribosomal protein S27a. (156 aa)
EP300Histone acetyltransferase p300. (2174 aa)
PSMB1Proteasome subunit beta. (241 aa)
PSMA1Proteasome subunit alpha type. (264 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa)
FBXL17F-box/LRR-repeat protein 17. (681 aa)
SESN1Sestrin-1 isoform X1. (551 aa)
SPATA5Spermatogenesis-associated protein 5. (782 aa)
TRIM58E3 ubiquitin-protein ligase TRIM58. (487 aa)
GCLMGlutamate--cysteine ligase regulatory subunit. (232 aa)
PSMD1426S proteasome non-ATPase regulatory subunit 14. (326 aa)
PSMA4Proteasome subunit alpha type. (179 aa)
SLC7A11Cystine/glutamate transporter isoform X1. (503 aa)
PSMF1Proteasome inhibitor PI31 subunit isoform X2. (272 aa)
PSME1Proteasome activator complex subunit 1 isoform X1. (250 aa)
PSMB2Proteasome subunit beta. (201 aa)
LOC103254447Gamma-secretase-activating protein. (175 aa)
PSMA8Proteasome subunit alpha type. (250 aa)
IDH1Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (414 aa)
TKTTransketolase. (413 aa)
PGD6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (485 aa)
SRXN1Sulfiredoxin 1. (137 aa)
CUL3Cullin-3; Belongs to the cullin family. (754 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (674 aa)
PSMB9Proteasome subunit beta. (219 aa)
PSMC126S protease regulatory subunit 4; Belongs to the AAA ATPase family. (440 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
LOC10327253526S proteasome non-ATPase regulatory subunit 7. (324 aa)
VCPTransitional endoplasmic reticulum ATPase; Belongs to the AAA ATPase family. (806 aa)
PSMC626S protease regulatory subunit 10B; Belongs to the AAA ATPase family. (403 aa)
ENSTSYP00000009770annotation not available (227 aa)
BACH1Transcription regulator protein BACH1. (739 aa)
SKP1S-phase kinase-associated protein 1 isoform X2; Belongs to the SKP1 family. (163 aa)
PSMD526S proteasome non-ATPase regulatory subunit 5 isoform X1. (513 aa)
KLHL18Kelch-like protein 18 isoform X2. (574 aa)
ME1Malic enzyme. (572 aa)
PSMA7Proteasome endopeptidase complex. (248 aa)
PRDX1Peroxiredoxin-1. (199 aa)
AKT3RAC-gamma serine/threonine-protein kinase; Belongs to the protein kinase superfamily. (419 aa)
TXNRD1Thioredoxin reductase 1, cytoplasmic. (567 aa)
PSMD626S proteasome non-ATPase regulatory subunit 6 isoform X1. (416 aa)
CSNK2A2Casein kinase II subunit alpha' isoform X2; Belongs to the protein kinase superfamily. (352 aa)
PSME4Proteasome activator complex subunit 4 isoform X2. (1825 aa)
TRIM21E3 ubiquitin-protein ligase TRIM21. (469 aa)
PSMD1126S proteasome non-ATPase regulatory subunit 11. (422 aa)
PSMB7Proteasome subunit beta. (277 aa)
PSMD326S proteasome non-ATPase regulatory subunit 3 isoform X2. (534 aa)
PSMB3Proteasome subunit beta. (207 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (623 aa)
PSMD1226S proteasome non-ATPase regulatory subunit 12. (420 aa)
PALB2Partner and localizer of BRCA2 isoform X1. (1177 aa)
UFD1Ubiquitin recognition factor in ER-associated degradation protein 1 isoform X1. (321 aa)
SQSTM1Sequestosome-1 isoform X2. (370 aa)
SESN2Sestrin-2. (480 aa)
PSMA6Proteasome subunit alpha type. (246 aa)
ENSTSYP00000014559annotation not available (115 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
GSK3BGlycogen synthase kinase-3 beta; Belongs to the protein kinase superfamily. (403 aa)
ENSTSYP00000015668annotation not available (251 aa)
PSMC326S protease regulatory subunit 6A; Belongs to the AAA ATPase family. (450 aa)
CUL1Cullin-1 isoform X1; Belongs to the cullin family. (776 aa)
LY6G5BLymphocyte antigen 6 complex locus protein G5b. (195 aa)
CSNK2A1Casein kinase II subunit alpha; Belongs to the protein kinase superfamily. (391 aa)
MAP1LC3BMicrotubule-associated proteins 1A/1B light chain 3B. (132 aa)
LOC103251634Transketolase-like. (146 aa)
ENSTSYP00000017997annotation not available (123 aa)
KIAA2012LOW QUALITY PROTEIN: uncharacterized protein KIAA2012 homolog; Belongs to the eukaryotic ribosomal protein P1/P2 family. (1143 aa)
GSRGlutathione reductase, mitochondrial. (490 aa)
ENSTSYP00000019039annotation not available (232 aa)
ENSTSYP00000019245annotation not available (285 aa)
PSMD1026S proteasome non-ATPase regulatory subunit 10 isoform X1. (226 aa)
RBX1E3 ubiquitin-protein ligase RBX1 isoform X2. (108 aa)
PSMB6Proteasome subunit beta. (242 aa)
SKP2S-phase kinase-associated protein 2. (436 aa)
ENSTSYP00000020999annotation not available (63 aa)
ENSTSYP00000021013annotation not available (135 aa)
PSME3Proteasome activator complex subunit 3 isoform X1. (265 aa)
ENSTSYP00000021540annotation not available (291 aa)
BTRCF-box/WD repeat-containing protein 1A isoform X1. (589 aa)
ENSTSYP00000022222annotation not available (155 aa)
BACH2Transcription regulator protein BACH2. (842 aa)
NPLOC4Nuclear protein localization protein 4 homolog. (608 aa)
ENSTSYP00000023689annotation not available (139 aa)
KLHL17Kelch-like protein 17. (596 aa)
UBA52ubiquitin-60S ribosomal protein L40 isoform X1. (231 aa)
MUL1Mitochondrial ubiquitin ligase activator of NFKB 1. (352 aa)
ENSTSYP00000024458annotation not available (182 aa)
ENSTSYP00000024485annotation not available (234 aa)
ENSTSYP00000024947annotation not available (143 aa)
ENSTSYP00000025007annotation not available (690 aa)
KEAP1Kelch-like ECH-associated protein 1. (621 aa)
ENSTSYP00000025346annotation not available (194 aa)
PSMD426S proteasome non-ATPase regulatory subunit 4 isoform X2. (377 aa)
PSMD926S proteasome non-ATPase regulatory subunit 9 isoform X1. (220 aa)
ENSTSYP00000025727annotation not available (215 aa)
PSMD1326S proteasome non-ATPase regulatory subunit 13 isoform X1. (396 aa)
UBXN7UBX domain-containing protein 7. (489 aa)
PSMB10Proteasome subunit beta. (273 aa)
HMOX1Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. (288 aa)
ENSTSYP00000027147annotation not available (149 aa)
CDKN1ACyclin-dependent kinase inhibitor 1. (164 aa)
ENSTSYP00000027311annotation not available (388 aa)
PSMC526S protease regulatory subunit 8 isoform X2; Belongs to the AAA ATPase family. (398 aa)
CSNK2BCasein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (235 aa)
G6PDGlucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (556 aa)
ENSTSYP00000028029annotation not available (442 aa)
ENSTSYP00000028373annotation not available (134 aa)
ENSTSYP00000028450annotation not available (227 aa)
ENSTSYP00000028770annotation not available (118 aa)
LOC10325039226S protease regulatory subunit 7; Belongs to the AAA ATPase family. (400 aa)
GCLCGlutamate--cysteine ligase catalytic subunit isoform X2. (637 aa)
ENSTSYP00000030504annotation not available (156 aa)
TXNRD3Thioredoxin reductase 3 isoform X1. (644 aa)
ENSTSYP00000030676annotation not available (108 aa)
MYCMyc proto-oncogene protein. (376 aa)
PSMB8Proteasome subunit beta. (276 aa)
ENSTSYP00000030893annotation not available (343 aa)
LOC103262238Proteasome subunit alpha type. (261 aa)
AKT1Non-specific serine/threonine protein kinase. (393 aa)
MTFP1Mitochondrial fission process protein 1 isoform X2. (166 aa)
BRCA1Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (180 aa)
ENSTSYP00000031721annotation not available (275 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
PSMB5Proteasome subunit beta. (263 aa)
NQO1NAD(P)H dehydrogenase [quinone] 1 isoform X1. (274 aa)
ENSTSYP00000032262annotation not available (99 aa)
TALDO1Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (304 aa)
PSME2Proteasome activator complex subunit 2 isoform X1. (254 aa)
ENSTSYP00000032718annotation not available (175 aa)
PSMC426S protease regulatory subunit 6B isoform X1; Belongs to the AAA ATPase family. (418 aa)
CREBBPCREB-binding protein isoform X1. (2433 aa)
NOTCH1Neurogenic locus notch homolog protein 1. (2339 aa)
ENSTSYP00000033058annotation not available (142 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
LOC110596262ubiquitin-40S ribosomal protein S27a-like. (156 aa)
ATF4Cyclic AMP-dependent transcription factor ATF-4 isoform X2. (352 aa)
ENSTSYP00000033562annotation not available (97 aa)
LOC103252213Breast cancer type 1 susceptibility protein-like. (97 aa)
ENSTSYP00000033656annotation not available (345 aa)
AMER1APC membrane recruitment protein 1. (789 aa)
ENSTSYP00000034030annotation not available (256 aa)
ENSTSYP00000034042annotation not available (110 aa)
DPP3Dipeptidyl peptidase 3; Belongs to the peptidase M49 family. (757 aa)
PSMD826S proteasome non-ATPase regulatory subunit 8. (264 aa)
MAFGTranscription factor MafG. (162 aa)
NFE2L1Nuclear factor erythroid 2-related factor 1 isoform X1. (772 aa)
Your Current Organism:
Carlito syrichta
NCBI taxonomy Id: 1868482
Other names: C. syrichta, Philippine tarsier, Tarsius syrichta
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