14 items (Carlito syrichta) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	EGFR	Receptor protein-tyrosine kinase. (1180 aa)
	EGF	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1167 aa)
	IGFBP1	Insulin-like growth factor-binding protein 1. (247 aa)
	PTGS2	Prostaglandin G/H synthase 2. (604 aa)
	COL4A1	Collagen alpha-1(IV) chain. (1621 aa)
	GNRHR	Gonadotropin-releasing hormone receptor isoform X1. (328 aa)
	LEPR	Leptin receptor. (961 aa)
	PTGES	Prostaglandin E synthase. (156 aa)
	ECM1	Extracellular matrix protein 1 isoform X2. (544 aa)
	PGR	Progesterone receptor. (338 aa)
	PRLR	Prolactin receptor; This is a receptor for the anterior pituitary hormone prolactin. (305 aa)
	AQP2	Aquaporin-2-like; Belongs to the MIP/aquaporin (TC 1.A.8) family. (264 aa)
	PRL	Prolactin. (228 aa)
	IGF1R	Tyrosine-protein kinase receptor. (1335 aa)

Your Current Organism:

Carlito syrichta

NCBI taxonomy Id: 1868482
Other names: C. syrichta, Philippine tarsier, Tarsius syrichta

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ECM1	PRL	ENSTSYP00000021764	ENSTSYP00000000439	Extracellular matrix protein 1 isoform X2.	Prolactin.	0.579
EGF	EGFR	ENSTSYP00000008584	ENSTSYP00000005737	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Receptor protein-tyrosine kinase.	0.999
EGF	IGF1R	ENSTSYP00000008584	ENSTSYP00000002092	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Tyrosine-protein kinase receptor.	0.928
EGF	LEPR	ENSTSYP00000008584	ENSTSYP00000014279	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Leptin receptor.	0.862
EGF	PGR	ENSTSYP00000008584	ENSTSYP00000022764	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Progesterone receptor.	0.505
EGF	PRL	ENSTSYP00000008584	ENSTSYP00000000439	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Prolactin.	0.448
EGF	PRLR	ENSTSYP00000008584	ENSTSYP00000027159	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Prolactin receptor; This is a receptor for the anterior pituitary hormone prolactin.	0.853
EGFR	EGF	ENSTSYP00000005737	ENSTSYP00000008584	Receptor protein-tyrosine kinase.	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	0.999
EGFR	IGF1R	ENSTSYP00000005737	ENSTSYP00000002092	Receptor protein-tyrosine kinase.	Tyrosine-protein kinase receptor.	0.954
EGFR	PGR	ENSTSYP00000005737	ENSTSYP00000022764	Receptor protein-tyrosine kinase.	Progesterone receptor.	0.741
EGFR	PRL	ENSTSYP00000005737	ENSTSYP00000000439	Receptor protein-tyrosine kinase.	Prolactin.	0.897
EGFR	PTGS2	ENSTSYP00000005737	ENSTSYP00000011373	Receptor protein-tyrosine kinase.	Prostaglandin G/H synthase 2.	0.543
IGF1R	EGF	ENSTSYP00000002092	ENSTSYP00000008584	Tyrosine-protein kinase receptor.	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	0.928
IGF1R	EGFR	ENSTSYP00000002092	ENSTSYP00000005737	Tyrosine-protein kinase receptor.	Receptor protein-tyrosine kinase.	0.954
IGF1R	IGFBP1	ENSTSYP00000002092	ENSTSYP00000010646	Tyrosine-protein kinase receptor.	Insulin-like growth factor-binding protein 1.	0.601
IGF1R	LEPR	ENSTSYP00000002092	ENSTSYP00000014279	Tyrosine-protein kinase receptor.	Leptin receptor.	0.476
IGF1R	PGR	ENSTSYP00000002092	ENSTSYP00000022764	Tyrosine-protein kinase receptor.	Progesterone receptor.	0.689
IGF1R	PRLR	ENSTSYP00000002092	ENSTSYP00000027159	Tyrosine-protein kinase receptor.	Prolactin receptor; This is a receptor for the anterior pituitary hormone prolactin.	0.404
IGFBP1	IGF1R	ENSTSYP00000010646	ENSTSYP00000002092	Insulin-like growth factor-binding protein 1.	Tyrosine-protein kinase receptor.	0.601
IGFBP1	PGR	ENSTSYP00000010646	ENSTSYP00000022764	Insulin-like growth factor-binding protein 1.	Progesterone receptor.	0.476