16 items (Carlito syrichta) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	EGFR	Receptor protein-tyrosine kinase. (1180 aa)
	RSPO4	R-spondin-4 isoform X1. (234 aa)
	RSPO2	R-spondin-2. (211 aa)
	INSRR	Tyrosine-protein kinase receptor. (1284 aa)
	INSR	Tyrosine-protein kinase receptor. (1356 aa)
	CRELD1	Cysteine-rich with EGF-like domain protein 1. (420 aa)
	FURIN	Furin; Belongs to the peptidase S8 family. (794 aa)
	RSPO1	R-spondin-1. (263 aa)
	ERBB2	Receptor protein-tyrosine kinase. (1255 aa)
	PCSK5	Proprotein convertase subtilisin/kexin type 5; Belongs to the peptidase S8 family. (1824 aa)
	CRELD2	Cysteine-rich with EGF-like domain protein 2 isoform X1. (390 aa)
	PCSK6	Proprotein convertase subtilisin/kexin type 6; Belongs to the peptidase S8 family. (969 aa)
	RSPO3	R-spondin-3. (244 aa)
	ERBB4	Receptor protein-tyrosine kinase. (1280 aa)
	FRAS1	Extracellular matrix protein FRAS1. (3336 aa)
	IGF1R	Tyrosine-protein kinase receptor. (1335 aa)

Your Current Organism:

Carlito syrichta

NCBI taxonomy Id: 1868482
Other names: C. syrichta, Philippine tarsier, Tarsius syrichta

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EGFR	ERBB2	ENSTSYP00000005737	ENSTSYP00000014181	Receptor protein-tyrosine kinase.	Receptor protein-tyrosine kinase.	0.999
EGFR	ERBB4	ENSTSYP00000005737	ENSTSYP00000006840	Receptor protein-tyrosine kinase.	Receptor protein-tyrosine kinase.	0.994
EGFR	IGF1R	ENSTSYP00000005737	ENSTSYP00000002092	Receptor protein-tyrosine kinase.	Tyrosine-protein kinase receptor.	0.954
EGFR	INSR	ENSTSYP00000005737	ENSTSYP00000023206	Receptor protein-tyrosine kinase.	Tyrosine-protein kinase receptor.	0.900
EGFR	INSRR	ENSTSYP00000005737	ENSTSYP00000023625	Receptor protein-tyrosine kinase.	Tyrosine-protein kinase receptor.	0.856
ERBB2	EGFR	ENSTSYP00000014181	ENSTSYP00000005737	Receptor protein-tyrosine kinase.	Receptor protein-tyrosine kinase.	0.999
ERBB2	ERBB4	ENSTSYP00000014181	ENSTSYP00000006840	Receptor protein-tyrosine kinase.	Receptor protein-tyrosine kinase.	0.994
ERBB2	IGF1R	ENSTSYP00000014181	ENSTSYP00000002092	Receptor protein-tyrosine kinase.	Tyrosine-protein kinase receptor.	0.969
ERBB2	INSR	ENSTSYP00000014181	ENSTSYP00000023206	Receptor protein-tyrosine kinase.	Tyrosine-protein kinase receptor.	0.932
ERBB2	INSRR	ENSTSYP00000014181	ENSTSYP00000023625	Receptor protein-tyrosine kinase.	Tyrosine-protein kinase receptor.	0.902
ERBB4	EGFR	ENSTSYP00000006840	ENSTSYP00000005737	Receptor protein-tyrosine kinase.	Receptor protein-tyrosine kinase.	0.994
ERBB4	ERBB2	ENSTSYP00000006840	ENSTSYP00000014181	Receptor protein-tyrosine kinase.	Receptor protein-tyrosine kinase.	0.994
ERBB4	IGF1R	ENSTSYP00000006840	ENSTSYP00000002092	Receptor protein-tyrosine kinase.	Tyrosine-protein kinase receptor.	0.818
ERBB4	INSR	ENSTSYP00000006840	ENSTSYP00000023206	Receptor protein-tyrosine kinase.	Tyrosine-protein kinase receptor.	0.717
ERBB4	INSRR	ENSTSYP00000006840	ENSTSYP00000023625	Receptor protein-tyrosine kinase.	Tyrosine-protein kinase receptor.	0.717
FRAS1	FURIN	ENSTSYP00000005885	ENSTSYP00000021024	Extracellular matrix protein FRAS1.	Furin; Belongs to the peptidase S8 family.	0.483
FRAS1	PCSK5	ENSTSYP00000005885	ENSTSYP00000012198	Extracellular matrix protein FRAS1.	Proprotein convertase subtilisin/kexin type 5; Belongs to the peptidase S8 family.	0.416
FRAS1	PCSK6	ENSTSYP00000005885	ENSTSYP00000011098	Extracellular matrix protein FRAS1.	Proprotein convertase subtilisin/kexin type 6; Belongs to the peptidase S8 family.	0.416
FRAS1	RSPO1	ENSTSYP00000005885	ENSTSYP00000014287	Extracellular matrix protein FRAS1.	R-spondin-1.	0.416
FRAS1	RSPO2	ENSTSYP00000005885	ENSTSYP00000024445	Extracellular matrix protein FRAS1.	R-spondin-2.	0.416