STRINGSTRING
HSPD1 HSPD1 CWH43 CWH43 MPHOSPH6 MPHOSPH6 DIS3L DIS3L EXD2 EXD2 CCT3 CCT3 ENO1 ENO1 EXOSC9 EXOSC9 XRN1 XRN1 TMEM87B TMEM87B LOC103258466 LOC103258466 DHX29 DHX29 DHX57 DHX57 CNOT6 CNOT6 ZCCHC7 ZCCHC7 CCT6B CCT6B PABPC1 PABPC1 CNBP CNBP EDC3 EDC3 SLC30A7 SLC30A7 LSM3 LSM3 LOC103268483 LOC103268483 UFSP2 UFSP2 PNLDC1 PNLDC1 DPH1 DPH1 PFKM PFKM NAXE NAXE BTG3 BTG3 BTG4 BTG4 PNPT1 PNPT1 PABPC1L PABPC1L DCPS DCPS ENO3 ENO3 ZCCHC2 ZCCHC2 MTREX MTREX DIS3 DIS3 CUNH19orf54 CUNH19orf54 CNOT3 CNOT3 DCP2 DCP2 XRN2 XRN2 DCP1B DCP1B PAPD5 PAPD5 CNOT6L CNOT6L VPS72 VPS72 ERMARD ERMARD EDC4 EDC4 PLXDC2 PLXDC2 PAM PAM TOE1 TOE1 LOC103270194 LOC103270194 DIS3L2 DIS3L2 EXOSC7 EXOSC7 SKIV2L SKIV2L MKKS MKKS ZCCHC9 ZCCHC9 KIF1BP KIF1BP WRN WRN PATL1 PATL1 ENSTSYP00000011700 ENSTSYP00000011700 BBS10 BBS10 DDX60L DDX60L EXOSC8 EXOSC8 EXOSC3 EXOSC3 TTC37 TTC37 WDR61 WDR61 IPO7 IPO7 HSPA9 HSPA9 PABPC4 PABPC4 DDX6 DDX6 IPO8 IPO8 EXOSC5 EXOSC5 WRAP73 WRAP73 ENSTSYP00000015055 ENSTSYP00000015055 CCT6A CCT6A SLC30A5 SLC30A5 LSM8 LSM8 PPP4R2 PPP4R2 CCT4 CCT4 TMEM87A TMEM87A ENSTSYP00000016868 ENSTSYP00000016868 NUDT6 NUDT6 ENSTSYP00000017201 ENSTSYP00000017201 ENO2 ENO2 HELZ2 HELZ2 ENSTSYP00000017666 ENSTSYP00000017666 DHX30 DHX30 ENO4 ENO4 ENSTSYP00000018357 ENSTSYP00000018357 SLC30A6 SLC30A6 PAN3 PAN3 TOB1 TOB1 CNOT8 CNOT8 FAM161A FAM161A PATL2 PATL2 LOC103275081 LOC103275081 PARN PARN LSM1 LSM1 CNOT10 CNOT10 DCP1A DCP1A PFKL PFKL ENSTSYP00000021424 ENSTSYP00000021424 LOC103263797 LOC103263797 NOCT NOCT ENSTSYP00000021957 ENSTSYP00000021957 LSM5 LSM5 PEG10 PEG10 BTG2 BTG2 ENSTSYP00000023222 ENSTSYP00000023222 EXOSC1 EXOSC1 LOC103253503 LOC103253503 CNOT4 CNOT4 ENSTSYP00000023805 ENSTSYP00000023805 PDE12 PDE12 DHX36 DHX36 PABPC5 PABPC5 NUDT18 NUDT18 CNOT1 CNOT1 ENSTSYP00000025289 ENSTSYP00000025289 ENSTSYP00000025529 ENSTSYP00000025529 PFKP PFKP ENSTSYP00000026107 ENSTSYP00000026107 PAPD7 PAPD7 CCT2 CCT2 ENSTSYP00000027231 ENSTSYP00000027231 ENSTSYP00000027446 ENSTSYP00000027446 CCT5 CCT5 CCT7 CCT7 LSM7 LSM7 LSM2 LSM2 EXOSC4 EXOSC4 LSM4 LSM4 CNOT9 CNOT9 ENSTSYP00000029418 ENSTSYP00000029418 ENSTSYP00000030075 ENSTSYP00000030075 ENSTSYP00000030270 ENSTSYP00000030270 PLXDC1 PLXDC1 EXOSC2 EXOSC2 C1D C1D LSM6 LSM6 ENSTSYP00000031193 ENSTSYP00000031193 ENSTSYP00000031394 ENSTSYP00000031394 LRRC27 LRRC27 DPH2 DPH2 TCP1 TCP1 ENSTSYP00000032793 ENSTSYP00000032793 ENSTSYP00000032963 ENSTSYP00000032963 LOC103266446 LOC103266446 TMEM176B TMEM176B PPIB PPIB EXOSC10 EXOSC10 ENSTSYP00000033720 ENSTSYP00000033720 CNOT2 CNOT2 ENSTSYP00000034334 ENSTSYP00000034334 PAN2 PAN2 PPIC PPIC CNOT7 CNOT7
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HSPD160 kDa heat shock protein, mitochondrial isoform X1; Belongs to the chaperonin (HSP60) family. (597 aa)
CWH43PGAP2-interacting protein-like. (596 aa)
MPHOSPH6M-phase phosphoprotein 6 isoform X1. (160 aa)
DIS3LDIS3-like exonuclease 1 isoform X1; Belongs to the RNR ribonuclease family. (1053 aa)
EXD2Exonuclease 3'-5' domain-containing protein 2. (620 aa)
CCT3T-complex protein 1 subunit gamma; Belongs to the TCP-1 chaperonin family. (404 aa)
ENO1Alpha-enolase isoform X1. (434 aa)
EXOSC9Exosome complex component RRP45 isoform X2. (440 aa)
XRN15'-3' exoribonuclease 1. (1695 aa)
TMEM87BTransmembrane protein 87B isoform X1. (557 aa)
LOC103258466Ankyrin repeat and KH domain-containing protein 1 isoform X3. (2534 aa)
DHX29ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily. (1365 aa)
DHX57Putative ATP-dependent RNA helicase DHX57 isoform X2. (1385 aa)
CNOT6CCR4-NOT transcription complex subunit 6. (557 aa)
ZCCHC7Zinc finger CCHC domain-containing protein 7. (542 aa)
CCT6BT-complex protein 1 subunit zeta-2 isoform X1. (531 aa)
PABPC1Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (636 aa)
CNBPCellular nucleic acid-binding protein isoform X2. (177 aa)
EDC3Enhancer of mRNA-decapping protein 3. (508 aa)
SLC30A7Zinc transporter 7. (376 aa)
LSM3U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (102 aa)
LOC103268483COBW domain-containing protein 3 isoform X1. (395 aa)
UFSP2Ufm1-specific protease 2 isoform X1. (469 aa)
PNLDC1poly(A)-specific ribonuclease PNLDC1. (531 aa)
DPH12-(3-amino-3-carboxypropyl)histidine synthase subunit 1; Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2. (447 aa)
PFKMATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (851 aa)
NAXENAD(P)H-hydrate epimerase; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX. (290 aa)
BTG3Protein BTG3. (252 aa)
BTG4Protein BTG4. (223 aa)
PNPT1Polyribonucleotide nucleotidyltransferase 1, mitochondrial isoform X1. (784 aa)
PABPC1LPolyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (614 aa)
DCPSm7GpppX diphosphatase isoform X1. (337 aa)
ENO3Beta-enolase isoform X1. (434 aa)
ZCCHC2Zinc finger CCHC domain-containing protein 2. (857 aa)
MTREXSuperkiller viralicidic activity 2-like 2 isoform X1. (969 aa)
DIS3Exosome complex exonuclease RRP44 isoform X1; Belongs to the RNR ribonuclease family. (954 aa)
CUNH19orf54UPF0692 protein C19orf54 homolog. (348 aa)
CNOT3CCR4-NOT transcription complex subunit 3. (747 aa)
DCP2m7GpppN-mRNA hydrolase isoform X1. (422 aa)
XRN25'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II. (949 aa)
DCP1BmRNA-decapping enzyme 1B isoform X1. (606 aa)
PAPD5Non-canonical poly(A) RNA polymerase PAPD5 isoform X1. (331 aa)
CNOT6LCCR4-NOT transcription complex subunit 6-like. (550 aa)
VPS72Vacuolar protein sorting-associated protein 72 homolog isoform X1. (364 aa)
ERMARDEndoplasmic reticulum membrane-associated RNA degradation protein isoform X1. (677 aa)
EDC4Enhancer of mRNA-decapping protein 4. (1398 aa)
PLXDC2Plexin domain-containing protein 2. (351 aa)
PAMPeptidyl-glycine alpha-amidating monooxygenase isoform X1. (983 aa)
TOE1Target of EGR1 protein 1 isoform X2. (510 aa)
LOC103270194Probable ATP-dependent RNA helicase DDX60. (1011 aa)
DIS3L2DIS3-like exonuclease 2. (544 aa)
EXOSC7Exosome complex component RRP42 isoform X1. (291 aa)
SKIV2LHelicase SKI2W isoform X1. (1246 aa)
MKKSMcKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin isoform X1. (570 aa)
ZCCHC9Zinc finger CCHC domain-containing protein 9. (267 aa)
KIF1BPKIF1-binding protein. (621 aa)
WRNLOW QUALITY PROTEIN: Werner syndrome ATP-dependent helicase. (1403 aa)
PATL1Protein PAT1 homolog 1. (802 aa)
ENSTSYP00000011700annotation not available (76 aa)
BBS10Bardet-Biedl syndrome 10 protein. (707 aa)
DDX60LProbable ATP-dependent RNA helicase DDX60-like. (1709 aa)
EXOSC8Exosome complex component RRP43. (276 aa)
EXOSC3Exosome complex component RRP40 isoform X1. (275 aa)
TTC37Tetratricopeptide repeat protein 37 isoform X1. (1561 aa)
WDR61WD repeat-containing protein 61 isoform X1. (305 aa)
IPO7Importin-7 isoform X1. (1038 aa)
HSPA9Stress-70 protein, mitochondrial isoform X1; Belongs to the heat shock protein 70 family. (679 aa)
PABPC4Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (660 aa)
DDX6Probable ATP-dependent RNA helicase DDX6 isoform X1; Belongs to the DEAD box helicase family. (483 aa)
IPO8Importin-8 isoform X1. (1037 aa)
EXOSC5Exosome complex component RRP46. (235 aa)
WRAP73WD repeat-containing protein WRAP73. (455 aa)
ENSTSYP00000015055annotation not available (592 aa)
CCT6AT-complex protein 1 subunit zeta isoform X1. (559 aa)
SLC30A5Zinc transporter 5. (764 aa)
LSM8U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. (96 aa)
PPP4R2Serine/threonine-protein phosphatase 4 regulatory subunit 2 isoform X1. (418 aa)
CCT4T-complex protein 1 subunit delta. (545 aa)
TMEM87ATransmembrane protein 87A isoform X1. (555 aa)
ENSTSYP00000016868annotation not available (192 aa)
NUDT6Nucleoside diphosphate-linked moiety X motif 6 isoform X4; Belongs to the Nudix hydrolase family. (147 aa)
ENSTSYP00000017201annotation not available (73 aa)
ENO2Gamma-enolase. (402 aa)
HELZ2LOW QUALITY PROTEIN: helicase with zinc finger domain 2. (2534 aa)
ENSTSYP00000017666annotation not available (385 aa)
DHX30Putative ATP-dependent RNA helicase DHX30 isoform X1. (1222 aa)
ENO4Enolase 4. (628 aa)
ENSTSYP00000018357annotation not available (414 aa)
SLC30A6Zinc transporter 6 isoform X1. (461 aa)
PAN3PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA deca [...] (743 aa)
TOB1Protein Tob1. (343 aa)
CNOT8CCR4-NOT transcription complex subunit 8 isoform X1. (292 aa)
FAM161AProtein FAM161A isoform X1. (715 aa)
PATL2Protein PAT1 homolog 2. (541 aa)
LOC103275081DIS3-like exonuclease 2. (124 aa)
PARNpoly(A)-specific ribonuclease PARN isoform X1. (65 aa)
LSM1U6 snRNA-associated Sm-like protein LSm1; Plays a role in the degradation of histone mRNAs, the only eukaryotic mRNAs that are not polyadenylated. Probably also part of an LSm subunits-containing complex involved in the general process of mRNA degradation. (133 aa)
CNOT10CCR4-NOT transcription complex subunit 10. (642 aa)
DCP1AmRNA-decapping enzyme 1A isoform X1. (582 aa)
PFKLATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (774 aa)
ENSTSYP00000021424annotation not available (514 aa)
LOC103263797Polyadenylate-binding protein 1-like 2. (200 aa)
NOCTNocturnin. (314 aa)
ENSTSYP00000021957annotation not available (116 aa)
LSM5U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA. (91 aa)
PEG10LOW QUALITY PROTEIN: retrotransposon-derived protein PEG10. (677 aa)
BTG2Protein BTG2. (163 aa)
ENSTSYP00000023222annotation not available (528 aa)
EXOSC1Exosome complex component CSL4 isoform X1. (198 aa)
LOC103253503T-complex protein 1 subunit gamma-like; Belongs to the TCP-1 chaperonin family. (258 aa)
CNOT4CCR4-NOT transcription complex subunit 4 isoform X2. (710 aa)
ENSTSYP00000023805annotation not available (94 aa)
PDE122',5'-phosphodiesterase 12 isoform X1. (609 aa)
DHX36ATP-dependent RNA helicase DHX36 isoform X1. (1005 aa)
PABPC5Polyadenylate-binding protein 5. (382 aa)
NUDT18LOW QUALITY PROTEIN: 8-oxo-dGDP phosphatase NUDT18; Belongs to the Nudix hydrolase family. (295 aa)
CNOT1CCR4-NOT transcription complex subunit 1 isoform X1. (2376 aa)
ENSTSYP00000025289annotation not available (149 aa)
ENSTSYP00000025529annotation not available (576 aa)
PFKPATP-dependent 6-phosphofructokinase, platelet type. (742 aa)
ENSTSYP00000026107annotation not available (252 aa)
PAPD7Non-canonical poly(A) RNA polymerase PAPD7 isoform X1. (542 aa)
CCT2T-complex protein 1 subunit beta. (535 aa)
ENSTSYP00000027231annotation not available (157 aa)
ENSTSYP00000027446annotation not available (493 aa)
CCT5T-complex protein 1 subunit epsilon isoform X1. (541 aa)
CCT7T-complex protein 1 subunit eta; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin. (543 aa)
LSM7U6 snRNA-associated Sm-like protein LSm7. (49 aa)
LSM2U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (95 aa)
EXOSC4Exosome complex component RRP41. (245 aa)
LSM4U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (139 aa)
CNOT9CCR4-NOT transcription complex subunit 9 isoform X1. (299 aa)
ENSTSYP00000029418annotation not available (59 aa)
ENSTSYP00000030075annotation not available (540 aa)
ENSTSYP00000030270annotation not available (92 aa)
PLXDC1Plexin domain-containing protein 1. (500 aa)
EXOSC2Exosome complex component RRP4 isoform X1. (293 aa)
C1DNuclear nucleic acid-binding protein C1D isoform X1. (141 aa)
LSM6U6 snRNA-associated Sm-like protein LSm6 isoform X2. (80 aa)
ENSTSYP00000031193annotation not available (420 aa)
ENSTSYP00000031394annotation not available (220 aa)
LRRC27Leucine-rich repeat-containing protein 27 isoform X1. (532 aa)
DPH22-(3-amino-3-carboxypropyl)histidine synthase subunit 2; Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2. (487 aa)
TCP1T-complex protein 1 subunit alpha isoform X1. (556 aa)
ENSTSYP00000032793annotation not available (555 aa)
ENSTSYP00000032963annotation not available (104 aa)
LOC103266446T-complex protein 1 subunit beta-like. (533 aa)
TMEM176BTransmembrane protein 176B. (263 aa)
PPIBPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (200 aa)
EXOSC10Exosome component 10. (862 aa)
ENSTSYP00000033720annotation not available (85 aa)
CNOT2CCR4-NOT transcription complex subunit 2 isoform X1. (550 aa)
ENSTSYP00000034334annotation not available (85 aa)
PAN2PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent [...] (1210 aa)
PPICPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (226 aa)
CNOT7CCR4-NOT transcription complex subunit 7 isoform X1. (285 aa)
Your Current Organism:
Carlito syrichta
NCBI taxonomy Id: 1868482
Other names: C. syrichta, Philippine tarsier, Tarsius syrichta
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