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CDC23 | Cell division cycle protein 23 homolog. (597 aa) | ||||
YWHAE | 14-3-3 protein epsilon isoform X2; Belongs to the 14-3-3 family. (255 aa) | ||||
ENSTSYP00000008181 | annotation not available (412 aa) | ||||
CDC25C | M-phase inducer phosphatase 3. (464 aa) | ||||
CDK7 | Cyclin-dependent kinase 7 isoform X1. (332 aa) | ||||
ENSTSYP00000035030 | annotation not available (263 aa) | ||||
ENSTSYP00000034921 | annotation not available (296 aa) | ||||
RBL2 | Retinoblastoma-like protein 2 isoform X1. (1141 aa) | ||||
MCM4 | DNA helicase; Belongs to the MCM family. (860 aa) | ||||
MAD2L2 | Mitotic spindle assembly checkpoint protein MAD2B. (223 aa) | ||||
CDK2 | Cyclin-dependent kinase 2 isoform X1; Belongs to the protein kinase superfamily. (346 aa) | ||||
ENSTSYP00000033058 | annotation not available (142 aa) | ||||
CREBBP | CREB-binding protein isoform X1. (2433 aa) | ||||
ENSTSYP00000033016 | annotation not available (307 aa) | ||||
BUB1 | Mitotic checkpoint serine/threonine-protein kinase BUB1 isoform X1. (1085 aa) | ||||
CDKN2D | Cyclin-dependent kinase 4 inhibitor D. (166 aa) | ||||
TGFB2 | Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa) | ||||
PRKDC | DNA-dependent protein kinase catalytic subunit; Belongs to the PI3/PI4-kinase family. (3073 aa) | ||||
ENSTSYP00000031351 | annotation not available (442 aa) | ||||
CNTD2 | LOW QUALITY PROTEIN: cyclin N-terminal domain-containing protein 2; Belongs to the cyclin family. (207 aa) | ||||
ENSTSYP00000031072 | annotation not available (165 aa) | ||||
TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (344 aa) | ||||
LOC103252110 | G2/mitotic-specific cyclin-B1 isoform X1; Belongs to the cyclin family. (433 aa) | ||||
MYC | Myc proto-oncogene protein. (376 aa) | ||||
PKMYT1 | Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase; Belongs to the protein kinase superfamily. (545 aa) | ||||
ENSTSYP00000030504 | annotation not available (156 aa) | ||||
ANAPC2 | Anaphase-promoting complex subunit 2. (577 aa) | ||||
ANAPC13 | Anaphase-promoting complex subunit 13. (74 aa) | ||||
TGFB3 | Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa) | ||||
SMAD3 | Mothers against decapentaplegic homolog. (425 aa) | ||||
YWHAH | 14-3-3 protein eta; Belongs to the 14-3-3 family. (246 aa) | ||||
ENSTSYP00000029126 | annotation not available (466 aa) | ||||
FZR1 | Fizzy-related protein homolog. (449 aa) | ||||
CCND2 | G1/S-specific cyclin-D2; Belongs to the cyclin family. (231 aa) | ||||
TMEM82 | Transmembrane protein 82. (360 aa) | ||||
CDKN1B | LOW QUALITY PROTEIN: cyclin-dependent kinase inhibitor 1B. (197 aa) | ||||
CDC14B | Dual specificity protein phosphatase CDC14B. (498 aa) | ||||
ZBTB47 | Zinc finger and BTB domain-containing protein 47. (713 aa) | ||||
CDKN1A | Cyclin-dependent kinase inhibitor 1. (164 aa) | ||||
CDKN2C | Cyclin-dependent kinase 4 inhibitor C. (168 aa) | ||||
PTTG1 | Securin isoform X1. (201 aa) | ||||
ANAPC10 | Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (185 aa) | ||||
LOC103252434 | Mitotic spindle assembly checkpoint protein MAD1-like. (243 aa) | ||||
HDAC1 | Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (482 aa) | ||||
CHEK2 | Serine/threonine-protein kinase Chk2 isoform X1. (582 aa) | ||||
RAD21L1 | Double-strand-break repair protein rad21-like protein 1. (553 aa) | ||||
CDK20 | Cyclin-dependent kinase 20 isoform X1. (288 aa) | ||||
ENSTSYP00000024958 | annotation not available (55 aa) | ||||
ENSTSYP00000024947 | annotation not available (143 aa) | ||||
YWHAQ | 14-3-3 protein theta; Belongs to the 14-3-3 family. (245 aa) | ||||
SFN | 14-3-3 protein sigma; Belongs to the 14-3-3 family. (248 aa) | ||||
ENSTSYP00000024257 | annotation not available (242 aa) | ||||
AP5S1 | AP-5 complex subunit sigma-1. (199 aa) | ||||
STAG1 | Cohesin subunit SA-1 isoform X1. (1258 aa) | ||||
E2F1 | Transcription factor E2F1. (350 aa) | ||||
ANAPC11 | Anaphase-promoting complex subunit 11 isoform X1. (84 aa) | ||||
CDC25B | M-phase inducer phosphatase 2 isoform X1. (575 aa) | ||||
TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (388 aa) | ||||
ENSTSYP00000023689 | annotation not available (139 aa) | ||||
ENSTSYP00000023430 | annotation not available (374 aa) | ||||
LOC103266579 | Growth arrest and DNA damage-inducible protein GADD45 alpha-like. (84 aa) | ||||
CCNE2 | G1/S-specific cyclin-E2 isoform X1; Belongs to the cyclin family. (404 aa) | ||||
LOC103250373 | E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (426 aa) | ||||
CHEK1 | Serine/threonine-protein kinase Chk1 isoform X1; Belongs to the protein kinase superfamily. (476 aa) | ||||
CCND1 | G1/S-specific cyclin-D1. (156 aa) | ||||
YWHAB | 14-3-3 protein beta/alpha isoform X1; Belongs to the 14-3-3 family. (246 aa) | ||||
MCM3 | DNA helicase; Belongs to the MCM family. (853 aa) | ||||
E2F3 | Transcription factor E2F3. (334 aa) | ||||
BUB3 | Mitotic checkpoint protein BUB3 isoform X1. (328 aa) | ||||
ENSTSYP00000021013 | annotation not available (135 aa) | ||||
SKP2 | S-phase kinase-associated protein 2. (436 aa) | ||||
CDC26 | Anaphase-promoting complex subunit CDC26 isoform X1. (85 aa) | ||||
RBX1 | E3 ubiquitin-protein ligase RBX1 isoform X2. (108 aa) | ||||
CDK1 | Cyclin-dependent kinase 1 isoform X1; Belongs to the protein kinase superfamily. (297 aa) | ||||
ENSTSYP00000019167 | annotation not available (267 aa) | ||||
PCNA | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa) | ||||
ZBTB10 | Zinc finger and BTB domain-containing protein 10. (697 aa) | ||||
CDKN2A | Cyclin-dependent kinase inhibitor 2A. (171 aa) | ||||
ENSTSYP00000017776 | annotation not available (292 aa) | ||||
CDC16 | Cell division cycle protein 16 homolog. (615 aa) | ||||
ANAPC1 | Anaphase-promoting complex subunit 1. (149 aa) | ||||
ENSTSYP00000017308 | annotation not available (305 aa) | ||||
CDC45 | Cell division control protein 45 homolog isoform X1. (600 aa) | ||||
ENSTSYP00000017183 | annotation not available (581 aa) | ||||
ORC6 | Origin recognition complex subunit 6. (252 aa) | ||||
ENSTSYP00000016277 | annotation not available (582 aa) | ||||
CUL1 | Cullin-1 isoform X1; Belongs to the cullin family. (776 aa) | ||||
CDK3 | Cyclin-dependent kinase 3 isoform X1; Belongs to the protein kinase superfamily. (305 aa) | ||||
GSK3B | Glycogen synthase kinase-3 beta; Belongs to the protein kinase superfamily. (403 aa) | ||||
CDC25A | M-phase inducer phosphatase 1 isoform X1. (523 aa) | ||||
FAM126B | Protein FAM126B isoform X2. (530 aa) | ||||
CCND3 | G1/S-specific cyclin-D3 isoform X1; Belongs to the cyclin family. (292 aa) | ||||
ENSTSYP00000014599 | annotation not available (238 aa) | ||||
ENSTSYP00000014079 | annotation not available (191 aa) | ||||
MCM5 | DNA replication licensing factor MCM5; Belongs to the MCM family. (598 aa) | ||||
SNAPIN | SNARE-associated protein Snapin; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling; Belongs to t [...] (136 aa) | ||||
STAG2 | Cohesin subunit SA-2 isoform X1. (1268 aa) | ||||
E2F5 | Transcription factor E2F5 isoform X1. (300 aa) | ||||
FBXW12 | F-box/WD repeat-containing protein 12. (465 aa) | ||||
ORC1 | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (858 aa) | ||||
CCNB2 | G2/mitotic-specific cyclin-B2; Belongs to the cyclin family. (398 aa) | ||||
CDK6 | Cyclin-dependent kinase 6. (264 aa) | ||||
CDC20 | Cell division cycle protein 20 homolog. (499 aa) | ||||
ANAPC5 | Anaphase-promoting complex subunit 5. (613 aa) | ||||
WEE2 | Wee1-like protein kinase. (567 aa) | ||||
MAD2L1 | Mitotic spindle assembly checkpoint protein MAD2A isoform X1. (205 aa) | ||||
CDC20B | Cell division cycle protein 20 homolog B isoform X1. (516 aa) | ||||
BUB1B | Mitotic checkpoint serine/threonine-protein kinase BUB1 beta. (1049 aa) | ||||
CDK4 | Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa) | ||||
CCNA2 | cyclin-A2; Belongs to the cyclin family. (430 aa) | ||||
ATR | Serine/threonine-protein kinase ATR; Belongs to the PI3/PI4-kinase family. (2644 aa) | ||||
MCM6 | DNA helicase; Belongs to the MCM family. (821 aa) | ||||
CDKN2B | Cyclin-dependent kinase 4 inhibitor B. (138 aa) | ||||
ANAPC7 | Anaphase-promoting complex subunit 7. (588 aa) | ||||
CCNE1 | G1/S-specific cyclin-E1. (410 aa) | ||||
SMC3 | Structural maintenance of chromosomes protein. (1208 aa) | ||||
SMAD2 | Mothers against decapentaplegic homolog. (467 aa) | ||||
SMC1A | Structural maintenance of chromosomes protein. (1235 aa) | ||||
CDC7 | Cell division cycle 7-related protein kinase isoform X1. (574 aa) | ||||
CCNA1 | cyclin-A1; Belongs to the cyclin family. (455 aa) | ||||
YWHAZ | 14-3-3 protein zeta/delta; Belongs to the 14-3-3 family. (254 aa) | ||||
MCM2 | DNA helicase; Belongs to the MCM family. (904 aa) | ||||
ORC3 | Origin recognition complex subunit 3 isoform X2. (711 aa) | ||||
ORC4 | Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (435 aa) | ||||
CDC6 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (559 aa) | ||||
E2F4 | Transcription factor E2F4. (407 aa) | ||||
CCNB3 | G2/mitotic-specific cyclin-B3; Belongs to the cyclin family. (1107 aa) | ||||
DBF4 | Protein DBF4 homolog A. (665 aa) | ||||
CDC27 | Cell division cycle protein 27 homolog isoform X1. (828 aa) | ||||
ABL1 | Tyrosine-protein kinase. (1148 aa) | ||||
MCM7 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (714 aa) | ||||
MYNN | Myoneurin isoform X1. (609 aa) | ||||
CDC14A | Dual specificity protein phosphatase CDC14A isoform X1. (575 aa) | ||||
RB1 | Retinoblastoma-associated protein. (929 aa) | ||||
PLK1 | Serine/threonine-protein kinase PLK. (604 aa) | ||||
ANAPC4 | Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (809 aa) | ||||
EP300 | Histone acetyltransferase p300. (2174 aa) | ||||
ENSTSYP00000000146 | annotation not available (178 aa) | ||||
ESPL1 | Separin. (1576 aa) | ||||
WEE1 | Wee1-like protein kinase. (432 aa) | ||||
CCNH | cyclin-H; Belongs to the cyclin family. (232 aa) | ||||
ZNF652 | Zinc finger protein 652. (608 aa) | ||||
SMC1B | Structural maintenance of chromosomes protein. (1235 aa) | ||||
SKP1 | S-phase kinase-associated protein 1 isoform X2; Belongs to the SKP1 family. (163 aa) | ||||
ZBTB46 | Zinc finger and BTB domain-containing protein 46. (589 aa) | ||||
ORC2 | Origin recognition complex subunit 2 isoform X1. (574 aa) | ||||
RBL1 | Retinoblastoma-like protein 1. (1068 aa) | ||||
YWHAG | 14-3-3 protein gamma; Belongs to the 14-3-3 family. (233 aa) | ||||
E2F2 | Transcription factor E2F2. (423 aa) | ||||
SMAD4 | Mothers against decapentaplegic homolog. (551 aa) | ||||
RAD21 | Double-strand-break repair protein rad21 homolog. (632 aa) | ||||
ATM | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3056 aa) | ||||
TTK | Dual specificity protein kinase TTK isoform X1. (851 aa) | ||||
HDAC2 | Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (458 aa) | ||||
TFDP2 | Transcription factor. (448 aa) |