STRINGSTRING
RRAS2 RRAS2 CSNK2A1 CSNK2A1 LY6G5B LY6G5B RASL11B RASL11B RHOT2 RHOT2 TFEC TFEC NPAS3 NPAS3 NBR1 NBR1 HIF1A HIF1A AGFG1 AGFG1 ENSTSYP00000034318 ENSTSYP00000034318 USP19 USP19 BNIP3L BNIP3L ENSTSYP00000033656 ENSTSYP00000033656 REM1 REM1 ATF4 ATF4 LOC110596262 LOC110596262 SRC SRC MITF MITF ENSTSYP00000032719 ENSTSYP00000032719 GEM GEM RRAD RRAD TBC1D15 TBC1D15 TFEB TFEB ENSTSYP00000017997 ENSTSYP00000017997 USP4 USP4 ENSTSYP00000018430 ENSTSYP00000018430 TBK1 TBK1 TBC1D17 TBC1D17 ATG9B ATG9B RAB7B RAB7B GABARAPL2 GABARAPL2 PINK1 PINK1 ATG5 ATG5 PGAM5 PGAM5 MRAS MRAS MFN2 MFN2 ENSTSYP00000020999 ENSTSYP00000020999 LOC103274018 LOC103274018 FUNDC1 FUNDC1 ENSTSYP00000022222 ENSTSYP00000022222 ENSTSYP00000022248 ENSTSYP00000022248 ENSTSYP00000023051 ENSTSYP00000023051 USP32 USP32 CALCOCO2 CALCOCO2 ENSTSYP00000023710 ENSTSYP00000023710 TP53 TP53 AGFG2 AGFG2 SPEN SPEN UBA52 UBA52 E2F1 E2F1 GABARAP GABARAP LOC103254373 LOC103254373 ENSTSYP00000014559 ENSTSYP00000014559 LOC103255477 LOC103255477 BCL2L1 BCL2L1 ENSTSYP00000013804 ENSTSYP00000013804 SQSTM1 SQSTM1 CFAP70 CFAP70 BCL2L13 BCL2L13 RRAS RRAS ATG9A ATG9A CSNK2A2 CSNK2A2 PDIK1L PDIK1L TOMM7 TOMM7 USP8 USP8 TFE3 TFE3 LOC103254964 LOC103254964 USP11 USP11 RHOT1 RHOT1 PRKN PRKN EIF2AK3 EIF2AK3 STK35 STK35 REM2 REM2 LOC103254447 LOC103254447 MAPK10 MAPK10 USP15 USP15 KRAS KRAS CSDE1 CSDE1 HRAS HRAS METTL17 METTL17 LOC103251373 LOC103251373 USP43 USP43 MFN1 MFN1 RAB7A RAB7A OPTN OPTN SP1 SP1 RPS27A RPS27A ENSTSYP00000000705 ENSTSYP00000000705 ENSTSYP00000029832 ENSTSYP00000029832 ENSTSYP00000030164 ENSTSYP00000030164 LOC103256674 LOC103256674 ENSTSYP00000030676 ENSTSYP00000030676 AMBRA1 AMBRA1 ENSTSYP00000030893 ENSTSYP00000030893 MAPK9 MAPK9 FIS1 FIS1 CITED2 CITED2 BECN1 BECN1 TAX1BP1 TAX1BP1 LOC103274931 LOC103274931 ULK1 ULK1 CSNK2B CSNK2B ENSTSYP00000027147 ENSTSYP00000027147 RIT1 RIT1 MAPK8 MAPK8 HIF3A HIF3A FUNDC2 FUNDC2 NRAS NRAS ENSTSYP00000024777 ENSTSYP00000024777 GABARAPL1 GABARAPL1 ENSTSYP00000024458 ENSTSYP00000024458 RELA RELA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RRAS2Ras-related protein R-Ras2. (204 aa)
CSNK2A1Casein kinase II subunit alpha; Belongs to the protein kinase superfamily. (391 aa)
LY6G5BLymphocyte antigen 6 complex locus protein G5b. (195 aa)
RASL11BRas-like protein family member 11B. (243 aa)
RHOT2Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family. (622 aa)
TFECTranscription factor EC isoform X2. (347 aa)
NPAS3Neuronal PAS domain-containing protein 3. (504 aa)
NBR1Next to BRCA1 gene 1 protein isoform X2. (959 aa)
HIF1AHypoxia-inducible factor 1-alpha isoform X1. (842 aa)
AGFG1arf-GAP domain and FG repeat-containing protein 1 isoform X2. (584 aa)
ENSTSYP00000034318annotation not available (114 aa)
USP19Ubiquitin carboxyl-terminal hydrolase 19 isoform X3. (1421 aa)
BNIP3LBCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like isoform X2. (219 aa)
ENSTSYP00000033656annotation not available (345 aa)
REM1GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (331 aa)
ATF4Cyclic AMP-dependent transcription factor ATF-4 isoform X2. (352 aa)
LOC110596262ubiquitin-40S ribosomal protein S27a-like. (156 aa)
SRCTyrosine-protein kinase. (542 aa)
MITFMicrophthalmia-associated transcription factor isoform X1. (419 aa)
ENSTSYP00000032719annotation not available (172 aa)
GEMGTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (296 aa)
RRADGTP-binding protein RAD. (275 aa)
TBC1D15TBC1 domain family member 15 isoform X1. (695 aa)
TFEBTranscription factor EB isoform X1. (485 aa)
ENSTSYP00000017997annotation not available (123 aa)
USP4Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (965 aa)
ENSTSYP00000018430annotation not available (163 aa)
TBK1Serine/threonine-protein kinase TBK1. (729 aa)
TBC1D17TBC1 domain family member 17. (582 aa)
ATG9BAutophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (917 aa)
RAB7BRas-related protein Rab-7b. (199 aa)
GABARAPL2Gamma-aminobutyric acid receptor-associated protein-like 2. (117 aa)
PINK1Serine/threonine-protein kinase PINK1, mitochondrial. (510 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
PGAM5Serine/threonine-protein phosphatase PGAM5, mitochondrial. (140 aa)
MRASRas-related protein M-Ras. (174 aa)
MFN2Mitofusin-2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (757 aa)
ENSTSYP00000020999annotation not available (63 aa)
LOC103274018ubiquitin-60S ribosomal protein L40-like isoform X2. (85 aa)
FUNDC1FUN14 domain-containing protein 1. (155 aa)
ENSTSYP00000022222annotation not available (155 aa)
ENSTSYP00000022248annotation not available (137 aa)
ENSTSYP00000023051annotation not available (95 aa)
USP32Ubiquitin carboxyl-terminal hydrolase 32; Belongs to the peptidase C19 family. (1614 aa)
CALCOCO2Calcium-binding and coiled-coil domain-containing protein 2 isoform X1. (469 aa)
ENSTSYP00000023710annotation not available (79 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (388 aa)
AGFG2arf-GAP domain and FG repeat-containing protein 2. (430 aa)
SPENMsx2-interacting protein. (3351 aa)
UBA52ubiquitin-60S ribosomal protein L40 isoform X1. (231 aa)
E2F1Transcription factor E2F1. (350 aa)
GABARAPGamma-aminobutyric acid receptor-associated protein. (117 aa)
LOC103254373BCL2/adenovirus E1B 19 kDa protein-interacting protein 3. (235 aa)
ENSTSYP00000014559annotation not available (115 aa)
LOC103255477Transcription factor Sp1-like. (259 aa)
BCL2L1Bcl-2-like protein 1 isoform X1. (233 aa)
ENSTSYP00000013804annotation not available (109 aa)
SQSTM1Sequestosome-1 isoform X2. (370 aa)
CFAP70Cilia- and flagella-associated protein 70 isoform X1. (1121 aa)
BCL2L13Bcl-2-like protein 13 isoform X1. (201 aa)
RRASRas-related protein R-Ras. (218 aa)
ATG9AAutophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (839 aa)
CSNK2A2Casein kinase II subunit alpha' isoform X2; Belongs to the protein kinase superfamily. (352 aa)
PDIK1LSerine/threonine-protein kinase PDIK1L. (295 aa)
TOMM7Mitochondrial import receptor subunit TOM7 homolog. (55 aa)
USP8Ubiquitin carboxyl-terminal hydrolase 8 isoform X1; Belongs to the peptidase C19 family. (1117 aa)
TFE3Transcription factor E3. (537 aa)
LOC103254964Ubiquitin carboxyl-terminal hydrolase 31; Belongs to the peptidase C19 family. (605 aa)
USP11Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (909 aa)
RHOT1Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family. (691 aa)
PRKNRBR-type E3 ubiquitin transferase. (220 aa)
EIF2AK3Eukaryotic translation initiation factor 2-alpha kinase 3. (1117 aa)
STK35Serine/threonine-protein kinase 35; Belongs to the protein kinase superfamily. (452 aa)
REM2GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (340 aa)
LOC103254447Gamma-secretase-activating protein. (175 aa)
MAPK10Mitogen-activated protein kinase. (473 aa)
USP15Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (955 aa)
KRASGTPase KRas isoform X1. (189 aa)
CSDE1Cold shock domain-containing protein E1 isoform X1. (842 aa)
HRASGTPase HRas isoform X6. (189 aa)
METTL17Methyltransferase-like protein 17, mitochondrial isoform X2. (461 aa)
LOC103251373GTP-binding protein Rit2. (100 aa)
USP43Ubiquitin carboxyl-terminal hydrolase 43; Belongs to the peptidase C19 family. (1121 aa)
MFN1Mitofusin-1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (744 aa)
RAB7ARas-related protein Rab-7a isoform X1. (214 aa)
OPTNOptineurin isoform X1. (571 aa)
SP1Transcription factor Sp1. (668 aa)
RPS27Aubiquitin-40S ribosomal protein S27a. (156 aa)
ENSTSYP00000000705annotation not available (144 aa)
ENSTSYP00000029832annotation not available (112 aa)
ENSTSYP00000030164annotation not available (98 aa)
LOC103256674LOW QUALITY PROTEIN: arf-GAP domain and FG repeat-containing protein 1-like. (465 aa)
ENSTSYP00000030676annotation not available (108 aa)
AMBRA1Activating molecule in BECN1-regulated autophagy protein 1. (1299 aa)
ENSTSYP00000030893annotation not available (343 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
FIS1Mitochondrial fission 1 protein. (128 aa)
CITED2Cbp/p300-interacting transactivator 2. (213 aa)
BECN1Beclin-1 isoform X4. (448 aa)
TAX1BP1Tax1-binding protein 1 isoform X1. (816 aa)
LOC103274931Ubiquitin carboxyl-terminal hydrolase 30; Belongs to the peptidase C19 family. (244 aa)
ULK1Serine/threonine-protein kinase ULK1. (1051 aa)
CSNK2BCasein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (235 aa)
ENSTSYP00000027147annotation not available (149 aa)
RIT1GTP-binding protein Rit1 isoform X1. (219 aa)
MAPK8Mitogen-activated protein kinase. (384 aa)
HIF3AHypoxia-inducible factor 3-alpha isoform X1. (669 aa)
FUNDC2FUN14 domain-containing protein 2 isoform X1. (189 aa)
NRASGTPase NRas. (189 aa)
ENSTSYP00000024777annotation not available (185 aa)
GABARAPL1Gamma-aminobutyric acid receptor-associated protein-like 1 isoform X2. (117 aa)
ENSTSYP00000024458annotation not available (182 aa)
RELATranscription factor p65. (519 aa)
Your Current Organism:
Carlito syrichta
NCBI taxonomy Id: 1868482
Other names: C. syrichta, Philippine tarsier, Tarsius syrichta
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