STRINGSTRING
PRKCQ PRKCQ ADORA2A ADORA2A CACNA1F CACNA1F MAPK1 MAPK1 ENSTSYP00000032766 ENSTSYP00000032766 ENSTSYP00000032829 ENSTSYP00000032829 RAMP1 RAMP1 PRKCG PRKCG LOC103257967 LOC103257967 LOC103268605 LOC103268605 AVPR1A AVPR1A KCNMB3 KCNMB3 LOC103249841 LOC103249841 ENSTSYP00000034769 ENSTSYP00000034769 LOC103255823 LOC103255823 ADCY2 ADCY2 LOC103249750 LOC103249750 PRKACB PRKACB PLA2G2F PLA2G2F AVPR1B AVPR1B PLA2G3 PLA2G3 PRKG1 PRKG1 PLA2G2A PLA2G2A LYVE1 LYVE1 ITPR2 ITPR2 CYP4B1 CYP4B1 ENSTSYP00000002295 ENSTSYP00000002295 NPR2 NPR2 CALCB CALCB PLA2G5 PLA2G5 PLA2G4B PLA2G4B PLA2G10 PLA2G10 PRKCA PRKCA PROCA1 PROCA1 LOC103250483 LOC103250483 AGT AGT MYLK3 MYLK3 LOC103264250 LOC103264250 ERF ERF ADORA2B ADORA2B PLA2G2C PLA2G2C ESYT2 ESYT2 PLA2G12B PLA2G12B PLA2G4F PLA2G4F PLA2G4D PLA2G4D RAF1 RAF1 PRKCD PRKCD PLA2G6 PLA2G6 CALCRL CALCRL MRVI1 MRVI1 CALD1 CALD1 PLCB4 PLCB4 GUCY1A3 GUCY1A3 LOC103272114 LOC103272114 ADRA1D ADRA1D BRAF BRAF ADCY9 ADCY9 PTGIR PTGIR PLCB1 PLCB1 PTRHD1 PTRHD1 ADCY3 ADCY3 LOC103249868 LOC103249868 LOC103259617 LOC103259617 PPP1CB PPP1CB MYLK4 MYLK4 EDN1 EDN1 ADCY8 ADCY8 PRKCB PRKCB ADRA1A ADRA1A LOC103268507 LOC103268507 ACTG2 ACTG2 NPPC NPPC EDN2 EDN2 LOC103256992 LOC103256992 LOC103250785 LOC103250785 AGTR1 AGTR1 PRKACA PRKACA PLA2G4C PLA2G4C EFCAB3 EFCAB3 ADCY4 ADCY4 CACNA1C CACNA1C MYLK MYLK PPP1R12B PPP1R12B KCNMB1 KCNMB1 ESYT1 ESYT1 ROCK2 ROCK2 PLA2G2E PLA2G2E ENSTSYP00000018500 ENSTSYP00000018500 ARHGEF11 ARHGEF11 MAP2K1 MAP2K1 KCNMB4 KCNMB4 PLA2G12A PLA2G12A RAMP3 RAMP3 ENSTSYP00000016797 ENSTSYP00000016797 ROCK1 ROCK1 MYL6B MYL6B RHOC RHOC AVP AVP LOC103250483-2 LOC103250483-2 PLCB3 PLCB3 CALML4 CALML4 LOC103255041 LOC103255041 LOC103269106 LOC103269106 LOC103263091 LOC103263091 ENSTSYP00000022482 ENSTSYP00000022482 ETV3 ETV3 ADCY6 ADCY6 ESYT3 ESYT3 ENSTSYP00000022821 ENSTSYP00000022821 ENSTSYP00000022866 ENSTSYP00000022866 GUCY1B3 GUCY1B3 PPP1R12C PPP1R12C JMJD7 JMJD7 PPP1R12A PPP1R12A CACNA1S CACNA1S ENSTSYP00000023933 ENSTSYP00000023933 LOC103255950 LOC103255950 PLA2G1B PLA2G1B ENSTSYP00000024356 ENSTSYP00000024356 ENSTSYP00000024479 ENSTSYP00000024479 RHOA RHOA MYH9 MYH9 LOC103249516 LOC103249516 ADCY7 ADCY7 ENSTSYP00000025025 ENSTSYP00000025025 PVALEF PVALEF KCNMB2 KCNMB2 GNA13 GNA13 GNA12 GNA12 LOC103261438 LOC103261438 PLCB2 PLCB2 LOC103251709 LOC103251709 RHOA-2 RHOA-2 LOC103253123 LOC103253123 EDN3 EDN3 NPPA NPPA ITPR3 ITPR3 ENSTSYP00000027244 ENSTSYP00000027244 MYLK2 MYLK2 ARHGEF12 ARHGEF12 PRKCH PRKCH ENSTSYP00000027677 ENSTSYP00000027677 ERFL ERFL MAPK3 MAPK3 PPP1CA PPP1CA ADRA1B ADRA1B ARHGEF1 ARHGEF1 ENSTSYP00000028505 ENSTSYP00000028505 PLA2G4A PLA2G4A ENSTSYP00000028865 ENSTSYP00000028865 ENSTSYP00000028986 ENSTSYP00000028986 CALML6 CALML6 MYH10 MYH10 CACNA1D CACNA1D LOC103252352 LOC103252352 ARAF ARAF RAMP2 RAMP2 ENSTSYP00000029868 ENSTSYP00000029868 MYL6 MYL6 LOC103252205 LOC103252205 ENSTSYP00000030021 ENSTSYP00000030021 CALCA CALCA ENSTSYP00000030425 ENSTSYP00000030425 ADCY5 ADCY5 ETV3L ETV3L EDNRA EDNRA CALM3 CALM3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (706 aa)
ADORA2AAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (412 aa)
CACNA1FVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1977 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (363 aa)
ENSTSYP00000032766annotation not available (382 aa)
ENSTSYP00000032829annotation not available (586 aa)
RAMP1Receptor activity-modifying protein 1 isoform X1. (158 aa)
PRKCGProtein kinase C. (634 aa)
LOC103257967Calmodulin-like; Belongs to the calmodulin family. (147 aa)
LOC103268605Calmodulin isoform X1; Belongs to the calmodulin family. (149 aa)
AVPR1AVasopressin V1a receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. (418 aa)
KCNMB3Calcium-activated potassium channel subunit beta-3. (273 aa)
LOC103249841Myosin light polypeptide 6-like. (152 aa)
ENSTSYP00000034769annotation not available (133 aa)
LOC103255823Guanine nucleotide-binding protein G(S) subunit alpha isoform X2. (361 aa)
ADCY2Adenylate cyclase type 2. (955 aa)
LOC103249750LOW QUALITY PROTEIN: cytochrome P450 4A11-like; Belongs to the cytochrome P450 family. (515 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily. (398 aa)
PLA2G2FPhospholipase A(2). (208 aa)
AVPR1BVasopressin V1b receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (425 aa)
PLA2G3Group 3 secretory phospholipase A2. (506 aa)
PRKG1cGMP-dependent protein kinase 1; Belongs to the protein kinase superfamily. (406 aa)
PLA2G2APhospholipase A(2). (144 aa)
LYVE1Lymphatic vessel endothelial hyaluronan receptor 1. (217 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2701 aa)
CYP4B1Cytochrome P450 4B1 isoform X1; Belongs to the cytochrome P450 family. (511 aa)
ENSTSYP00000002295annotation not available (173 aa)
NPR2Guanylate cyclase. (1047 aa)
CALCBCalcitonin gene-related peptide 2-like. (138 aa)
PLA2G5Phospholipase A(2). (138 aa)
PLA2G4BPhospholipase A2. (781 aa)
PLA2G10Phospholipase A(2). (163 aa)
PRKCAProtein kinase C. (614 aa)
PROCA1Protein PROCA1 isoform X2. (336 aa)
LOC103250483calmodulin-A-like isoform X1; Belongs to the calmodulin family. (150 aa)
AGTAngiotensinogen; Belongs to the serpin family. (487 aa)
MYLK3Myosin light chain kinase 3. (477 aa)
LOC103264250Rho guanine nucleotide exchange factor 11-like. (581 aa)
ERFETS domain-containing transcription factor ERF. (542 aa)
ADORA2BAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (332 aa)
PLA2G2CPhospholipase A(2). (148 aa)
ESYT2Extended synaptotagmin-2. (771 aa)
PLA2G12BGroup XIIB secretory phospholipase A2-like protein isoform X1. (195 aa)
PLA2G4FPhospholipase A2. (849 aa)
PLA2G4DPhospholipase A2. (806 aa)
RAF1RAF proto-oncogene serine/threonine-protein kinase isoform X1. (668 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (674 aa)
PLA2G685/88 kDa calcium-independent phospholipase A2 isoform X1. (807 aa)
CALCRLCalcitonin gene-related peptide type 1 receptor; Belongs to the G-protein coupled receptor 2 family. (462 aa)
MRVI1Protein MRVI1 isoform X1. (911 aa)
CALD1Caldesmon 1. (451 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1194 aa)
GUCY1A3Guanylate cyclase soluble subunit alpha-3 isoform X1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (690 aa)
LOC103272114Protein kinase C epsilon type. (220 aa)
ADRA1DLOW QUALITY PROTEIN: alpha-1D adrenergic receptor. (500 aa)
BRAFSerine/threonine-protein kinase B-raf. (760 aa)
ADCY9Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa)
PTGIRProstacyclin receptor. (171 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1135 aa)
PTRHD1Putative peptidyl-tRNA hydrolase PTRHD1. (140 aa)
ADCY3Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1145 aa)
LOC103249868Cytosolic phospholipase A2 epsilon. (452 aa)
LOC103259617Cytochrome P450 4A11-like isoform X1; Belongs to the cytochrome P450 family. (455 aa)
PPP1CBSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (313 aa)
MYLK4Myosin light chain kinase family member 4; Belongs to the protein kinase superfamily. (389 aa)
EDN1Endothelin-1. (202 aa)
ADCY8Adenylate cyclase type 8; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (931 aa)
PRKCBNon-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (531 aa)
ADRA1Aalpha-1A adrenergic receptor isoform X1. (466 aa)
LOC103268507Guanylate cyclase soluble subunit beta-2. (709 aa)
ACTG2Actin, gamma-enteric smooth muscle isoform X1. (376 aa)
NPPCC-type natriuretic peptide. (129 aa)
EDN2Endothelin-2. (178 aa)
LOC103256992Inositol 1,4,5-trisphosphate receptor type 1. (1004 aa)
LOC103250785Guanylate cyclase soluble subunit alpha-2-like. (402 aa)
AGTR1Type-1 angiotensin II receptor; Belongs to the G-protein coupled receptor 1 family. (387 aa)
PRKACAcAMP-dependent protein kinase catalytic subunit alpha; Belongs to the protein kinase superfamily. (343 aa)
PLA2G4CCytosolic phospholipase A2 gamma. (520 aa)
EFCAB3EF-hand calcium-binding domain-containing protein 3. (460 aa)
ADCY4Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2045 aa)
MYLKMyosin light chain kinase, smooth muscle isoform X1. (1917 aa)
PPP1R12BProtein phosphatase 1 regulatory subunit 12B. (886 aa)
KCNMB1Calcium-activated potassium channel subunit beta-1. (191 aa)
ESYT1Extended synaptotagmin-1 isoform X1. (1091 aa)
ROCK2Rho-associated protein kinase 2 isoform X1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1376 aa)
PLA2G2EPhospholipase A(2). (142 aa)
ENSTSYP00000018500annotation not available (73 aa)
ARHGEF11Rho guanine nucleotide exchange factor 11. (920 aa)
MAP2K1Dual specificity mitogen-activated protein kinase kinase 1. (381 aa)
KCNMB4Calcium-activated potassium channel subunit beta-4. (210 aa)
PLA2G12AGroup XIIA secretory phospholipase A2. (189 aa)
RAMP3Receptor activity-modifying protein 3 isoform X2. (147 aa)
ENSTSYP00000016797annotation not available (58 aa)
ROCK1Rho-associated protein kinase 1 isoform X1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1367 aa)
MYL6BMyosin light chain 6B. (207 aa)
RHOCRho-related GTP-binding protein RhoC isoform X2. (193 aa)
AVPVasopressin-neurophysin 2-copeptin; Belongs to the vasopressin/oxytocin family. (107 aa)
LOC103250483-2Calmodulin-2/4-like isoform X2; Belongs to the calmodulin family. (141 aa)
PLCB3Phosphoinositide phospholipase C. (828 aa)
CALML4LOW QUALITY PROTEIN: calmodulin-like protein 4. (192 aa)
LOC103255041Myosin-11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2012 aa)
LOC103269106cGMP-dependent protein kinase 1-like. (187 aa)
LOC103263091Adenylate cyclase type 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (293 aa)
ENSTSYP00000022482annotation not available (178 aa)
ETV3ETS translocation variant 3. (511 aa)
ADCY6Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1166 aa)
ESYT3Extended synaptotagmin-3. (752 aa)
ENSTSYP00000022821annotation not available (43 aa)
ENSTSYP00000022866annotation not available (318 aa)
GUCY1B3Guanylate cyclase soluble subunit beta-1 isoform X1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (623 aa)
PPP1R12CLOW QUALITY PROTEIN: protein phosphatase 1 regulatory subunit 12C. (578 aa)
JMJD7jmjC domain-containing protein 7. (308 aa)
PPP1R12AProtein phosphatase 1 regulatory subunit. (1030 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1868 aa)
ENSTSYP00000023933annotation not available (330 aa)
LOC103255950Calmodulin-like; Belongs to the calmodulin family. (131 aa)
PLA2G1BPhospholipase A(2). (147 aa)
ENSTSYP00000024356annotation not available (326 aa)
ENSTSYP00000024479annotation not available (60 aa)
RHOATransforming protein RhoA isoform X7. (81 aa)
MYH9Myosin-9 isoform X1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1952 aa)
LOC103249516Inositol 1,4,5-trisphosphate receptor type 1. (389 aa)
ADCY7Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1071 aa)
ENSTSYP00000025025annotation not available (362 aa)
PVALEFParvalbumin like EF-hand containing. (134 aa)
KCNMB2Calcium-activated potassium channel subunit beta-2. (235 aa)
GNA13Guanine nucleotide-binding protein subunit alpha-13. (282 aa)
GNA12Guanine nucleotide-binding protein subunit alpha-12. (304 aa)
LOC103261438Calmodulin-like; Belongs to the calmodulin family. (130 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1094 aa)
LOC103251709Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (348 aa)
RHOA-2Transforming protein RhoA isoform X1. (193 aa)
LOC103253123Adenylate cyclase type 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (327 aa)
EDN3Endothelin-3 isoform X1. (214 aa)
NPPANatriuretic peptides A. (153 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2677 aa)
ENSTSYP00000027244annotation not available (133 aa)
MYLK2Myosin light chain kinase 2, skeletal/cardiac muscle. (559 aa)
ARHGEF12Rho guanine nucleotide exchange factor 12. (124 aa)
PRKCHProtein kinase C eta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that is involved in the regulation of cell differentiation in keratinocytes and pre-B cell receptor, mediates regulation of epithelial tight junction integrity and foam cell formation, and is required for glioblastoma proliferation and apoptosis prevention in MCF-7 cells. In keratinocytes, binds and activates the tyrosine kinase FYN, which in turn blocks epidermal growth factor receptor (EGFR) signaling and leads to keratinocyte growth arrest and differentia [...] (683 aa)
ENSTSYP00000027677annotation not available (152 aa)
ERFLETS domain-containing transcription factor ERF. (354 aa)
MAPK3Mitogen-activated protein kinase. (363 aa)
PPP1CASerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (322 aa)
ADRA1Balpha-1B adrenergic receptor. (510 aa)
ARHGEF1Rho guanine nucleotide exchange factor 1. (966 aa)
ENSTSYP00000028505annotation not available (242 aa)
PLA2G4APhospholipase A2. (749 aa)
ENSTSYP00000028865annotation not available (429 aa)
ENSTSYP00000028986annotation not available (137 aa)
CALML6Calmodulin-like protein 6. (164 aa)
MYH10Myosin-10 isoform X2; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2007 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2028 aa)
LOC103252352Myosin-14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (547 aa)
ARAFSerine/threonine-protein kinase A-Raf isoform X1. (611 aa)
RAMP2Receptor activity-modifying protein 2. (100 aa)
ENSTSYP00000029868annotation not available (246 aa)
MYL6LOW QUALITY PROTEIN: myosin light polypeptide 6. (171 aa)
LOC103252205Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (337 aa)
ENSTSYP00000030021annotation not available (162 aa)
CALCACalcitonin isoform X2. (142 aa)
ENSTSYP00000030425annotation not available (102 aa)
ADCY5Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (915 aa)
ETV3LETS translocation variant 3-like protein. (357 aa)
EDNRAEndothelin-1 receptor isoform X1; Belongs to the G-protein coupled receptor 1 family. (427 aa)
CALM3Calmodulin 3. (128 aa)
Your Current Organism:
Carlito syrichta
NCBI taxonomy Id: 1868482
Other names: C. syrichta, Philippine tarsier, Tarsius syrichta
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