STRINGSTRING
PIK3CD PIK3CD PIK3CB PIK3CB REM1 REM1 PRKCG PRKCG SRC SRC PPP3CB PPP3CB RAC2 RAC2 MAPK1 MAPK1 SH2D2A SH2D2A GEM GEM RRAD RRAD CDC42 CDC42 ENSTSYP00000031441 ENSTSYP00000031441 MAPKAPK2 MAPKAPK2 AKT1 AKT1 ENSTSYP00000030193 ENSTSYP00000030193 ENSTSYP00000029618 ENSTSYP00000029618 PLA2G4A PLA2G4A MAPK3 MAPK3 LOC103251709 LOC103251709 MAPK13 MAPK13 MAPK11 MAPK11 NOS3 NOS3 PIK3R3 PIK3R3 PTK2 PTK2 SH2D7 SH2D7 NRAS NRAS ENSTSYP00000024479 ENSTSYP00000024479 ENSTSYP00000024401 ENSTSYP00000024401 PPP3CA PPP3CA JMJD7 JMJD7 TGFB1I1 TGFB1I1 ENSTSYP00000021856 ENSTSYP00000021856 PIK3R1 PIK3R1 VEGFA VEGFA MAP2K1 MAP2K1 MAPK12 MAPK12 SPHK2 SPHK2 ENSTSYP00000017214 ENSTSYP00000017214 ENSTSYP00000016797 ENSTSYP00000016797 RAC1 RAC1 LRRC45 LRRC45 PLCG2 PLCG2 AKT2 AKT2 ENSTSYP00000014856 ENSTSYP00000014856 PPP3R1 PPP3R1 RAC3 RAC3 PLA2G4C PLA2G4C PTGS2 PTGS2 PRKCB PRKCB AKT3 AKT3 LOC103249868 LOC103249868 LPXN LPXN RAF1 RAF1 PLA2G4D PLA2G4D PLA2G4F PLA2G4F NFATC2 NFATC2 PXN PXN KRAS KRAS KDR KDR PIK3CA PIK3CA PLCG1 PLCG1 PRKCA PRKCA PPP3CC PPP3CC CSDE1 CSDE1 HRAS HRAS PLA2G4B PLA2G4B CASP9 CASP9 MAPKAPK3 MAPKAPK3 MAPK14 MAPK14 SPHK1 SPHK1 ENSTSYP00000000627 ENSTSYP00000000627
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1063 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X2; Belongs to the PI3/PI4-kinase family. (1070 aa)
REM1GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (331 aa)
PRKCGProtein kinase C. (634 aa)
SRCTyrosine-protein kinase. (542 aa)
PPP3CBSerine/threonine-protein phosphatase. (525 aa)
RAC2Ras-related C3 botulinum toxin substrate 2 isoform X1. (192 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (363 aa)
SH2D2ASH2 domain-containing protein 2A isoform X1. (398 aa)
GEMGTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (296 aa)
RRADGTP-binding protein RAD. (275 aa)
CDC42Cell division control protein 42 homolog. (191 aa)
ENSTSYP00000031441annotation not available (131 aa)
MAPKAPK2MAP kinase-activated protein kinase 2. (400 aa)
AKT1Non-specific serine/threonine protein kinase. (393 aa)
ENSTSYP00000030193annotation not available (164 aa)
ENSTSYP00000029618annotation not available (173 aa)
PLA2G4APhospholipase A2. (749 aa)
MAPK3Mitogen-activated protein kinase. (363 aa)
LOC103251709Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (348 aa)
MAPK13Mitogen-activated protein kinase. (365 aa)
MAPK11Mitogen-activated protein kinase. (255 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1209 aa)
PIK3R3Phosphatidylinositol 3-kinase regulatory subunit gamma isoform X2. (461 aa)
PTK2Focal adhesion kinase 1 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1096 aa)
SH2D7SH2 domain-containing protein 7. (442 aa)
NRASGTPase NRas. (189 aa)
ENSTSYP00000024479annotation not available (60 aa)
ENSTSYP00000024401annotation not available (186 aa)
PPP3CASerine/threonine-protein phosphatase. (521 aa)
JMJD7jmjC domain-containing protein 7. (308 aa)
TGFB1I1Transforming growth factor beta-1-induced transcript 1 protein; Belongs to the paxillin family. (456 aa)
ENSTSYP00000021856annotation not available (88 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (612 aa)
VEGFAVascular endothelial growth factor A isoform X2; Belongs to the PDGF/VEGF growth factor family. (186 aa)
MAP2K1Dual specificity mitogen-activated protein kinase kinase 1. (381 aa)
MAPK12Mitogen-activated protein kinase. (277 aa)
SPHK2Sphingosine kinase 2 isoform X1. (654 aa)
ENSTSYP00000017214annotation not available (178 aa)
ENSTSYP00000016797annotation not available (58 aa)
RAC1Ras-related C3 botulinum toxin substrate 1. (212 aa)
LRRC45Leucine-rich repeat-containing protein 45. (670 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
ENSTSYP00000014856annotation not available (69 aa)
PPP3R1Calcineurin subunit B type 1. (169 aa)
RAC3Ras-related C3 botulinum toxin substrate 3. (192 aa)
PLA2G4CCytosolic phospholipase A2 gamma. (520 aa)
PTGS2Prostaglandin G/H synthase 2. (604 aa)
PRKCBNon-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (531 aa)
AKT3RAC-gamma serine/threonine-protein kinase; Belongs to the protein kinase superfamily. (419 aa)
LOC103249868Cytosolic phospholipase A2 epsilon. (452 aa)
LPXNLeupaxin; Belongs to the paxillin family. (391 aa)
RAF1RAF proto-oncogene serine/threonine-protein kinase isoform X1. (668 aa)
PLA2G4DPhospholipase A2. (806 aa)
PLA2G4FPhospholipase A2. (849 aa)
NFATC2Nuclear factor of activated T-cells, cytoplasmic 2 isoform X1. (921 aa)
PXNLOW QUALITY PROTEIN: paxillin. (1079 aa)
KRASGTPase KRas isoform X1. (189 aa)
KDRVascular endothelial growth factor receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1302 aa)
PRKCAProtein kinase C. (614 aa)
PPP3CCSerine/threonine-protein phosphatase. (514 aa)
CSDE1Cold shock domain-containing protein E1 isoform X1. (842 aa)
HRASGTPase HRas isoform X6. (189 aa)
PLA2G4BPhospholipase A2. (781 aa)
CASP9Caspase-9; Belongs to the peptidase C14A family. (410 aa)
MAPKAPK3MAP kinase-activated protein kinase 3; Belongs to the protein kinase superfamily. (383 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
SPHK1Sphingosine kinase 1. (438 aa)
ENSTSYP00000000627annotation not available (167 aa)
Your Current Organism:
Carlito syrichta
NCBI taxonomy Id: 1868482
Other names: C. syrichta, Philippine tarsier, Tarsius syrichta
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