STRINGSTRING
ENSTSYP00000022866 ENSTSYP00000022866 BMP7 BMP7 TGFBR1 TGFBR1 TEAD2 TEAD2 LOC103251546 LOC103251546 BMP2 BMP2 ENSTSYP00000034117 ENSTSYP00000034117 ENSTSYP00000033992 ENSTSYP00000033992 WNT10B WNT10B CCN2 CCN2 LATS2 LATS2 WNT2B WNT2B ENSTSYP00000032419 ENSTSYP00000032419 LOC103275739 LOC103275739 SNAI2 SNAI2 WNT4 WNT4 CTNNA3 CTNNA3 TGFB2 TGFB2 TGFB1 TGFB1 DVL2 DVL2 MYC MYC LOC103268676 LOC103268676 ENSTSYP00000030184 ENSTSYP00000030184 LOC103252205 LOC103252205 TGFB3 TGFB3 SMAD3 SMAD3 YWHAH YWHAH CCND2 CCND2 SERPINE1 SERPINE1 WNT5B WNT5B MPP5 MPP5 AXIN1 AXIN1 PPP1CA PPP1CA WNT10A WNT10A FRMD6 FRMD6 DVL3 DVL3 LOC103254672 LOC103254672 SAV1 SAV1 ACTL8 ACTL8 DLG2 DLG2 SMAD4 SMAD4 PARD3 PARD3 CTNNA2 CTNNA2 AREG AREG WNT16 WNT16 LDAH LDAH YWHAG YWHAG PPP1CB PPP1CB TCF7 TCF7 RASSF6 RASSF6 FZD9 FZD9 YWHAZ YWHAZ ENSTSYP00000020233 ENSTSYP00000020233 BMPR1A BMPR1A MYO15B MYO15B ID2 ID2 ENSTSYP00000019494 ENSTSYP00000019494 ENSTSYP00000019483 ENSTSYP00000019483 ENSTSYP00000019285 ENSTSYP00000019285 ENSTSYP00000019212 ENSTSYP00000019212 ENSTSYP00000019175 ENSTSYP00000019175 ENSTSYP00000019167 ENSTSYP00000019167 NF2 NF2 TEAD3 TEAD3 FGF1 FGF1 PPP2R2B PPP2R2B AXIN2 AXIN2 PPP2R1A PPP2R1A MOB1A MOB1A BIRC5 BIRC5 ITGB2 ITGB2 LIMD1 LIMD1 BIRC3 BIRC3 ENSTSYP00000016704 ENSTSYP00000016704 PPP2R1B PPP2R1B HAUS4 HAUS4 FBXW11 FBXW11 YAP1 YAP1 CSNK1D CSNK1D TCF7L1 TCF7L1 MYO15A MYO15A GDF5 GDF5 SCRIB SCRIB GSK3B GSK3B CRB2 CRB2 WNT7B WNT7B CCND3 CCND3 ENSTSYP00000014599 ENSTSYP00000014599 DLG3 DLG3 PRKCI PRKCI NKD2 NKD2 SMAD1 SMAD1 PPP2CA PPP2CA ENSTSYP00000013967 ENSTSYP00000013967 WNT3 WNT3 DLG1 DLG1 PPP2CB PPP2CB DLG4 DLG4 PARD6A PARD6A PARD6B PARD6B WNT7A WNT7A GDF6 GDF6 CRB1 CRB1 LLGL1 LLGL1 PATJ PATJ CTNNB1 CTNNB1 ENSTSYP00000034959 ENSTSYP00000034959 PPP2R2C PPP2R2C TCF7L2 TCF7L2 LLGL2 LLGL2 ENSTSYP00000026804 ENSTSYP00000026804 TEAD4 TEAD4 WNT3A WNT3A BMP4 BMP4 RASSF1 RASSF1 ENSTSYP00000025800 ENSTSYP00000025800 WNT1 WNT1 WNT11 WNT11 APC APC WNT8A WNT8A YWHAQ YWHAQ ENSTSYP00000024257 ENSTSYP00000024257 ENSTSYP00000024219 ENSTSYP00000024219 WNT5A WNT5A BMPR2 BMPR2 LEF1 LEF1 WNT9A WNT9A TP73 TP73 WNT6 WNT6 LATS1 LATS1 LOC103268188 LOC103268188 SMAD7 SMAD7 LOC103267969 LOC103267969 FZD4 FZD4 CCND1 CCND1 PRKCZ PRKCZ YWHAB YWHAB BTRC BTRC PPP2R2A PPP2R2A ENSTSYP00000021791 ENSTSYP00000021791 LOC103250886 LOC103250886 CTNNA1 CTNNA1 CDH1 CDH1 WNT9B WNT9B AJUBA AJUBA SMAD2 SMAD2 BMP6 BMP6 AMOT AMOT FZD6 FZD6 MOB1B MOB1B BMPR1B BMPR1B AFP AFP TGFBR2 TGFBR2 ENSTSYP00000001543 ENSTSYP00000001543 TEAD1 TEAD1 PPP2R2D PPP2R2D BMP5 BMP5 ACTL7B ACTL7B ENSTSYP00000006227 ENSTSYP00000006227 LOC103269416 LOC103269416 DLG5 DLG5 WWTR1 WWTR1 WNT2 WNT2 NKD1 NKD1 FZD3 FZD3 YWHAE YWHAE
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSTSYP00000022866annotation not available (318 aa)
BMP7Bone morphogenetic protein 7. (431 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (487 aa)
TEAD2Transcriptional enhancer factor TEF-4 isoform X1. (456 aa)
LOC103251546Baculoviral IAP repeat-containing protein 2. (310 aa)
BMP2Bone morphogenetic protein 2. (398 aa)
ENSTSYP00000034117annotation not available (246 aa)
ENSTSYP00000033992annotation not available (46 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
CCN2Connective tissue growth factor. (297 aa)
LATS2Serine/threonine-protein kinase LATS2. (611 aa)
WNT2BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (330 aa)
ENSTSYP00000032419annotation not available (240 aa)
LOC103275739Casein kinase I; Belongs to the protein kinase superfamily. (416 aa)
SNAI2Zinc finger protein SNAI2. (268 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
CTNNA3Catenin alpha-3. (184 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (344 aa)
DVL2Segment polarity protein dishevelled homolog DVL-2 isoform X1. (736 aa)
MYCMyc proto-oncogene protein. (376 aa)
LOC103268676Cadherin-1-like. (413 aa)
ENSTSYP00000030184annotation not available (260 aa)
LOC103252205Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (337 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
YWHAH14-3-3 protein eta; Belongs to the 14-3-3 family. (246 aa)
CCND2G1/S-specific cyclin-D2; Belongs to the cyclin family. (231 aa)
SERPINE1Plasminogen activator inhibitor 1; Belongs to the serpin family. (402 aa)
WNT5BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (359 aa)
MPP5MAGUK p55 subfamily member 5; Belongs to the MAGUK family. (675 aa)
AXIN1Axin-1. (574 aa)
PPP1CASerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (322 aa)
WNT10AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (397 aa)
FRMD6FERM domain-containing protein 6 isoform X1. (622 aa)
DVL3Segment polarity protein dishevelled homolog DVL-3 isoform X1. (685 aa)
LOC103254672Leucine-rich repeat-containing protein 1. (471 aa)
SAV1Protein salvador homolog 1 isoform X1. (384 aa)
ACTL8LOW QUALITY PROTEIN: actin-like protein 8; Belongs to the actin family. (366 aa)
DLG2Disks large homolog 2. (784 aa)
SMAD4Mothers against decapentaplegic homolog. (551 aa)
PARD3Partitioning defective 3 homolog isoform X1. (1356 aa)
CTNNA2Catenin alpha-2 isoform X1. (555 aa)
AREGAmphiregulin isoform X1. (270 aa)
WNT16Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
LDAHLipid droplet-associated hydrolase. (155 aa)
YWHAG14-3-3 protein gamma; Belongs to the 14-3-3 family. (233 aa)
PPP1CBSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (313 aa)
TCF7Transcription factor 7 isoform X1. (400 aa)
RASSF6Ras association domain-containing protein 6 isoform X3. (354 aa)
FZD9Frizzled-9; Belongs to the G-protein coupled receptor Fz/Smo family. (365 aa)
YWHAZ14-3-3 protein zeta/delta; Belongs to the 14-3-3 family. (254 aa)
ENSTSYP00000020233annotation not available (371 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
MYO15BMyosin XVB. (1590 aa)
ID2DNA-binding protein inhibitor ID-2. (129 aa)
ENSTSYP00000019494annotation not available (501 aa)
ENSTSYP00000019483annotation not available (478 aa)
ENSTSYP00000019285annotation not available (346 aa)
ENSTSYP00000019212annotation not available (259 aa)
ENSTSYP00000019175annotation not available (491 aa)
ENSTSYP00000019167annotation not available (267 aa)
NF2Merlin isoform X1. (598 aa)
TEAD3Transcriptional enhancer factor TEF-5. (360 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
PPP2R2BSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (484 aa)
AXIN2Axin-2. (649 aa)
PPP2R1ASerine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform isoform X1. (589 aa)
MOB1AMOB kinase activator 1A isoform X1. (217 aa)
BIRC5Baculoviral IAP repeat-containing protein 5 isoform X1. (142 aa)
ITGB2Integrin beta. (769 aa)
LIMD1LIM domain-containing protein 1. (674 aa)
BIRC3Baculoviral IAP repeat-containing protein 3. (603 aa)
ENSTSYP00000016704annotation not available (357 aa)
PPP2R1BSerine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform isoform X3. (667 aa)
HAUS4HAUS augmin-like complex subunit 4 isoform X1. (363 aa)
FBXW11F-box/WD repeat-containing protein 11 isoform X1. (533 aa)
YAP1Transcriptional coactivator YAP1 isoform X1. (326 aa)
CSNK1DCasein kinase I isoform X3; Belongs to the protein kinase superfamily. (428 aa)
TCF7L1Transcription factor 7-like 1. (499 aa)
MYO15AUnconventional myosin-XV; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (789 aa)
GDF5Growth/differentiation factor 5. (499 aa)
SCRIBProtein scribble homolog isoform X1. (1649 aa)
GSK3BGlycogen synthase kinase-3 beta; Belongs to the protein kinase superfamily. (403 aa)
CRB2Protein crumbs homolog 2. (1092 aa)
WNT7BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
CCND3G1/S-specific cyclin-D3 isoform X1; Belongs to the cyclin family. (292 aa)
ENSTSYP00000014599annotation not available (238 aa)
DLG3Disks large homolog 3 isoform X1; Belongs to the MAGUK family. (839 aa)
PRKCIProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (598 aa)
NKD2Protein naked cuticle homolog 2. (419 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
ENSTSYP00000013967annotation not available (167 aa)
WNT3Wnt family member 3. (239 aa)
DLG1Disks large homolog 1 isoform X5; Belongs to the MAGUK family. (460 aa)
PPP2CBSerine/threonine-protein phosphatase. (309 aa)
DLG4Disks large homolog 4 isoform X1; Belongs to the MAGUK family. (765 aa)
PARD6APartitioning defective 6 homolog alpha. (346 aa)
PARD6BPartitioning defective 6 homolog beta. (372 aa)
WNT7AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (297 aa)
GDF6Growth/differentiation factor 6. (457 aa)
CRB1Protein crumbs homolog 1. (674 aa)
LLGL1Lethal(2) giant larvae protein homolog 1. (1059 aa)
PATJinaD-like protein. (1786 aa)
CTNNB1Catenin beta-1 isoform X1. (783 aa)
ENSTSYP00000034959annotation not available (168 aa)
PPP2R2CSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (307 aa)
TCF7L2Transcription factor 7-like 2 isoform X1. (565 aa)
LLGL2Lethal(2) giant larvae protein homolog 2. (935 aa)
ENSTSYP00000026804annotation not available (402 aa)
TEAD4Transcriptional enhancer factor TEF-3 isoform X1. (546 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
BMP4Bone morphogenetic protein 4 isoform X1. (409 aa)
RASSF1Ras association domain-containing protein 1 isoform X1. (344 aa)
ENSTSYP00000025800annotation not available (1001 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (387 aa)
APCAdenomatous polyposis coli protein isoform X2. (2844 aa)
WNT8AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (356 aa)
YWHAQ14-3-3 protein theta; Belongs to the 14-3-3 family. (245 aa)
ENSTSYP00000024257annotation not available (242 aa)
ENSTSYP00000024219annotation not available (592 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1035 aa)
LEF1Lymphoid enhancer-binding factor 1 isoform X2. (399 aa)
WNT9AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (364 aa)
TP73Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. (637 aa)
WNT6Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (366 aa)
LATS1Serine/threonine-protein kinase LATS1. (1131 aa)
LOC103268188Zinc finger protein GLI2. (760 aa)
SMAD7Mothers against decapentaplegic homolog 7 isoform X1. (211 aa)
LOC103267969Catenin alpha-2-like. (235 aa)
FZD4Frizzled-4; Belongs to the G-protein coupled receptor Fz/Smo family. (507 aa)
CCND1G1/S-specific cyclin-D1. (156 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (558 aa)
YWHAB14-3-3 protein beta/alpha isoform X1; Belongs to the 14-3-3 family. (246 aa)
BTRCF-box/WD repeat-containing protein 1A isoform X1. (589 aa)
PPP2R2ASerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (457 aa)
ENSTSYP00000021791annotation not available (63 aa)
LOC103250886Segment polarity protein dishevelled homolog DVL-1-like. (373 aa)
CTNNA1Catenin alpha-1 isoform X1. (908 aa)
CDH1Cadherin-1; Cadherins are calcium-dependent cell adhesion proteins. (443 aa)
WNT9BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (335 aa)
AJUBALIM domain-containing protein ajuba. (513 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
BMP6Bone morphogenetic protein 6. (513 aa)
AMOTAngiomotin. (1101 aa)
FZD6Frizzled-6 isoform X1; Belongs to the G-protein coupled receptor Fz/Smo family. (703 aa)
MOB1BMOB kinase activator 1B. (216 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (480 aa)
AFPAlpha-fetoprotein. (605 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (558 aa)
ENSTSYP00000001543annotation not available (134 aa)
TEAD1Transcriptional enhancer factor TEF-1 isoform X2. (426 aa)
PPP2R2DSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (343 aa)
BMP5Bone morphogenetic protein 5 isoform X1. (454 aa)
ACTL7BLOW QUALITY PROTEIN: actin-like protein 7B; Belongs to the actin family. (366 aa)
ENSTSYP00000006227annotation not available (515 aa)
LOC103269416Baculoviral IAP repeat-containing protein 2-like. (340 aa)
DLG5Disks large homolog 5; Belongs to the MAGUK family. (1921 aa)
WWTR1WW domain-containing transcription regulator protein 1. (400 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
NKD1Protein naked cuticle homolog 1. (458 aa)
FZD3Frizzled-3; Belongs to the G-protein coupled receptor Fz/Smo family. (603 aa)
YWHAE14-3-3 protein epsilon isoform X2; Belongs to the 14-3-3 family. (255 aa)
Your Current Organism:
Carlito syrichta
NCBI taxonomy Id: 1868482
Other names: C. syrichta, Philippine tarsier, Tarsius syrichta
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