STRINGSTRING
LOC103269362 LOC103269362 MAPK10 MAPK10 MAP2K3 MAP2K3 NFKB1 NFKB1 CHUK CHUK IFNAR1 IFNAR1 CCL5 CCL5 ENSTSYP00000006680 ENSTSYP00000006680 MYD88 MYD88 TAB2 TAB2 IL1B IL1B BPI BPI LOC103254943 LOC103254943 TLR3 TLR3 AKT3 AKT3 RIPK1 RIPK1 MAP3K8 MAP3K8 BPIFC BPIFC IL12B IL12B MAP2K7 MAP2K7 PIK3CA PIK3CA CXCL8 CXCL8 NFKBIA NFKBIA TLR4 TLR4 IKBKB IKBKB LBP LBP IRAK4 IRAK4 MAPK14 MAPK14 IL12A IL12A CXCL10 CXCL10 CD14 CD14 LY96 LY96 LOC103274157 LOC103274157 LOC103271590 LOC103271590 AKT2 AKT2 MAP2K4 MAP2K4 CD80 CD80 CTSK CTSK IRF7 IRF7 IRF3 IRF3 PIK3CB PIK3CB CXCL9 CXCL9 MAPK1 MAPK1 TAB1 TAB1 IL6 IL6 MAPK9 MAPK9 IRAK1 IRAK1 AKT1 AKT1 MAP3K7 MAP3K7 CASP8 CASP8 TMED7 TMED7 PIK3CD PIK3CD FOS FOS CD86 CD86 IRF6 IRF6 MAPK3 MAPK3 IRF5 IRF5 TNF TNF IKBKE IKBKE TOLLIP TOLLIP LOC103251709 LOC103251709 MAPK13 MAPK13 TMED3 TMED3 MAPK11 MAPK11 IKBKG IKBKG MAPK8 MAPK8 PIK3R3 PIK3R3 LOC103249528 LOC103249528 RELA RELA MAP2K6 MAP2K6 TIRAP TIRAP TRAF3 TRAF3 SPP1 SPP1 CD40 CD40 PIK3R1 PIK3R1 LOC103254389 LOC103254389 TLR7 TLR7 TBK1 TBK1 MAP2K1 MAP2K1 LOC103255929 LOC103255929 MAPK12 MAPK12 LOC103271195 LOC103271195 TRAF6 TRAF6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC103269362Interferon alpha/beta receptor 2. (278 aa)
MAPK10Mitogen-activated protein kinase. (473 aa)
MAP2K3Dual specificity mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (347 aa)
NFKB1Nuclear factor NF-kappa-B p105 subunit isoform X1. (964 aa)
CHUKInhibitor of nuclear factor kappa-B kinase subunit alpha. (744 aa)
IFNAR1Interferon alpha/beta receptor 1. (561 aa)
CCL5C-C motif chemokine. (91 aa)
ENSTSYP00000006680annotation not available (255 aa)
MYD88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (321 aa)
TAB2TGF-beta-activated kinase 1 and MAP3K7-binding protein 2. (693 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (267 aa)
BPIBactericidal permeability-increasing protein. (508 aa)
LOC103254943C-X-C motif chemokine. (102 aa)
TLR3Toll-like receptor 3; Belongs to the Toll-like receptor family. (905 aa)
AKT3RAC-gamma serine/threonine-protein kinase; Belongs to the protein kinase superfamily. (419 aa)
RIPK1Receptor-interacting serine/threonine-protein kinase 1. (671 aa)
MAP3K8Mitogen-activated protein kinase kinase kinase 8. (467 aa)
BPIFCBPI fold-containing family C protein. (507 aa)
IL12BInterleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (326 aa)
MAP2K7Dual specificity mitogen-activated protein kinase kinase 7. (414 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
CXCL8Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (95 aa)
NFKBIANF-kappa-B inhibitor alpha. (282 aa)
TLR4Toll-like receptor 4 isoform X1; Belongs to the Toll-like receptor family. (840 aa)
IKBKBInhibitor of nuclear factor kappa-B kinase subunit beta isoform X1. (756 aa)
LBPLipopolysaccharide-binding protein. (481 aa)
IRAK4Interleukin-1 receptor-associated kinase 4. (460 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
IL12AInterleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (233 aa)
CXCL10C-X-C motif chemokine. (98 aa)
CD14Monocyte differentiation antigen CD14. (376 aa)
LY96Lymphocyte antigen 96 isoform X1. (160 aa)
LOC103274157Interferon alpha-17-like. (189 aa)
LOC103271590C-X-C motif chemokine. (100 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
MAP2K4Dual specificity mitogen-activated protein kinase kinase 4 isoform X1; Belongs to the protein kinase superfamily. (387 aa)
CD80T-lymphocyte activation antigen CD80. (232 aa)
CTSKCathepsin K isoform X1; Belongs to the peptidase C1 family. (329 aa)
IRF7Interferon regulatory factor 7. (133 aa)
IRF3Interferon regulatory factor 3 isoform X2. (426 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X2; Belongs to the PI3/PI4-kinase family. (1070 aa)
CXCL9C-X-C motif chemokine. (126 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (363 aa)
TAB1TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 isoform X2. (504 aa)
IL6Interleukin-6. (209 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
IRAK1Interleukin-1 receptor-associated kinase 1. (618 aa)
AKT1Non-specific serine/threonine protein kinase. (393 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
CASP8Caspase-8; Belongs to the peptidase C14A family. (521 aa)
TMED7Transmembrane emp24 domain-containing protein 7. (229 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1063 aa)
FOSProto-oncogene c-Fos. (379 aa)
CD86T-lymphocyte activation antigen CD86. (273 aa)
IRF6Interferon regulatory factor 6 isoform X1. (467 aa)
MAPK3Mitogen-activated protein kinase. (363 aa)
IRF5Interferon regulatory factor 5 isoform X1. (502 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (232 aa)
IKBKEInhibitor of nuclear factor kappa-B kinase subunit epsilon isoform X1. (718 aa)
TOLLIPToll-interacting protein. (238 aa)
LOC103251709Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (348 aa)
MAPK13Mitogen-activated protein kinase. (365 aa)
TMED3Transmembrane emp24 domain-containing protein 3. (217 aa)
MAPK11Mitogen-activated protein kinase. (255 aa)
IKBKGNF-kappa-B essential modulator. (460 aa)
MAPK8Mitogen-activated protein kinase. (384 aa)
PIK3R3Phosphatidylinositol 3-kinase regulatory subunit gamma isoform X2. (461 aa)
LOC103249528Interferon alpha/beta receptor 2-like. (236 aa)
RELATranscription factor p65. (519 aa)
MAP2K6LOW QUALITY PROTEIN: dual specificity mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (352 aa)
TIRAPToll/interleukin-1 receptor domain-containing adapter protein isoform X1. (228 aa)
TRAF3TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (568 aa)
SPP1Osteopontin isoform X1. (314 aa)
CD40Tumor necrosis factor receptor superfamily member 5 isoform X2. (277 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (612 aa)
LOC103254389C-C motif chemokine 4 isoform X2. (98 aa)
TLR7Toll-like receptor 7; Belongs to the Toll-like receptor family. (1050 aa)
TBK1Serine/threonine-protein kinase TBK1. (729 aa)
MAP2K1Dual specificity mitogen-activated protein kinase kinase 1. (381 aa)
LOC103255929Toll-like receptor 9 isoform X2. (1029 aa)
MAPK12Mitogen-activated protein kinase. (277 aa)
LOC103271195C-C motif chemokine. (91 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (512 aa)
Your Current Organism:
Carlito syrichta
NCBI taxonomy Id: 1868482
Other names: C. syrichta, Philippine tarsier, Tarsius syrichta
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