STRINGSTRING
MAPK8 MAPK8 IKBKG IKBKG MAPK11 MAPK11 MAPK13 MAPK13 IKBKE IKBKE TNF TNF TRIM47 TRIM47 TRIM65 TRIM65 TBKBP1 TBKBP1 CASP8 CASP8 MAP3K7 MAP3K7 MAPK9 MAPK9 TANK TANK RNF135 RNF135 FGFR1OP2 FGFR1OP2 IRF3 IRF3 IRF7 IRF7 IL12A IL12A CXCL10 CXCL10 DDX3X DDX3X NFKBIA NFKBIA IKBKB IKBKB RNF125 RNF125 MAVS MAVS NFKBIB NFKBIB TKFC TKFC MAPK14 MAPK14 CYLD CYLD TBK1 TBK1 PIN1 PIN1 NLRX1 NLRX1 ATG5 ATG5 TMEM173 TMEM173 MAPK12 MAPK12 TRAF6 TRAF6 DHX58 DHX58 LOC103274157 LOC103274157 TRIM25 TRIM25 LOC103262174 LOC103262174 LOC103271013 LOC103271013 ISG15 ISG15 OTUD5 OTUD5 IL12B IL12B ATG12 ATG12 RIPK1 RIPK1 CASP10 CASP10 MAP3K1 MAP3K1 MAPK10 MAPK10 IFIH1 IFIH1 COIL COIL NFKB1 NFKB1 CHUK CHUK DDX58 DDX58 SIKE1 SIKE1 CXCL8 CXCL8 TRAF3 TRAF3 TRADD TRADD AZI2 AZI2 RELA RELA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MAPK8Mitogen-activated protein kinase. (384 aa)
IKBKGNF-kappa-B essential modulator. (460 aa)
MAPK11Mitogen-activated protein kinase. (255 aa)
MAPK13Mitogen-activated protein kinase. (365 aa)
IKBKEInhibitor of nuclear factor kappa-B kinase subunit epsilon isoform X1. (718 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (232 aa)
TRIM47Tripartite motif-containing protein 47. (467 aa)
TRIM65Tripartite motif-containing protein 65. (381 aa)
TBKBP1TANK-binding kinase 1-binding protein 1. (215 aa)
CASP8Caspase-8; Belongs to the peptidase C14A family. (521 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
TANKTRAF family member-associated NF-kappa-B activator. (422 aa)
RNF135E3 ubiquitin-protein ligase RNF135. (401 aa)
FGFR1OP2FGFR1 oncogene partner 2 isoform X1. (255 aa)
IRF3Interferon regulatory factor 3 isoform X2. (426 aa)
IRF7Interferon regulatory factor 7. (133 aa)
IL12AInterleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (233 aa)
CXCL10C-X-C motif chemokine. (98 aa)
DDX3XATP-dependent RNA helicase DDX3X isoform X1; Belongs to the DEAD box helicase family. (725 aa)
NFKBIANF-kappa-B inhibitor alpha. (282 aa)
IKBKBInhibitor of nuclear factor kappa-B kinase subunit beta isoform X1. (756 aa)
RNF125E3 ubiquitin-protein ligase RNF125. (191 aa)
MAVSMitochondrial antiviral-signaling protein. (521 aa)
NFKBIBNF-kappa-B inhibitor beta isoform X2. (343 aa)
TKFCtriokinase/FMN cyclase. (578 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
CYLDUbiquitin carboxyl-terminal hydrolase CYLD; Belongs to the peptidase C19 family. (953 aa)
TBK1Serine/threonine-protein kinase TBK1. (729 aa)
PIN1Peptidyl-prolyl cis-trans isomerase. (163 aa)
NLRX1NLR family member X1. (974 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
TMEM173Stimulator of interferon genes protein. (379 aa)
MAPK12Mitogen-activated protein kinase. (277 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (512 aa)
DHX58Probable ATP-dependent RNA helicase DHX58. (388 aa)
LOC103274157Interferon alpha-17-like. (189 aa)
TRIM25E3 ubiquitin/ISG15 ligase TRIM25. (619 aa)
LOC103262174ATP-dependent RNA helicase DDX3X-like; Belongs to the DEAD box helicase family. (608 aa)
LOC103271013Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (141 aa)
ISG15Ubiquitin-like protein ISG15. (165 aa)
OTUD5OTU domain-containing protein 5 isoform X8. (448 aa)
IL12BInterleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (326 aa)
ATG12Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (140 aa)
RIPK1Receptor-interacting serine/threonine-protein kinase 1. (671 aa)
CASP10Caspase-10; Belongs to the peptidase C14A family. (471 aa)
MAP3K1Mitogen-activated protein kinase kinase kinase 1. (1346 aa)
MAPK10Mitogen-activated protein kinase. (473 aa)
IFIH1Interferon-induced helicase C domain-containing protein 1. (1025 aa)
COILCoilin. (536 aa)
NFKB1Nuclear factor NF-kappa-B p105 subunit isoform X1. (964 aa)
CHUKInhibitor of nuclear factor kappa-B kinase subunit alpha. (744 aa)
DDX58Probable ATP-dependent RNA helicase DDX58. (926 aa)
SIKE1Suppressor of IKBKE 1 isoform X1. (211 aa)
CXCL8Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (95 aa)
TRAF3TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (568 aa)
TRADDTumor necrosis factor receptor type 1-associated DEATH domain protein isoform X2. (310 aa)
AZI25-azacytidine-induced protein 2. (390 aa)
RELATranscription factor p65. (519 aa)
Your Current Organism:
Carlito syrichta
NCBI taxonomy Id: 1868482
Other names: C. syrichta, Philippine tarsier, Tarsius syrichta
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