STRINGSTRING
HRAS HRAS FCER1A FCER1A LYN LYN VAV3 VAV3 SOS2 SOS2 MAPK14 MAPK14 ALOX5 ALOX5 IL13 IL13 MS4A2 MS4A2 PLA2G4B PLA2G4B SOS1 SOS1 CSDE1 CSDE1 PRKCA PRKCA PLCG1 PLCG1 PIK3CA PIK3CA KRAS KRAS MAP2K3 MAP2K3 MAPK10 MAPK10 PDPK1 PDPK1 PLA2G4F PLA2G4F PLA2G4D PLA2G4D RAF1 RAF1 CSF2 CSF2 BTK BTK IL4 IL4 LOC103249868 LOC103249868 IL5 IL5 AKT3 AKT3 INPP5D INPP5D PLA2G4C PLA2G4C RAC3 RAC3 FYN FYN ENSTSYP00000014000 ENSTSYP00000014000 MAP2K7 MAP2K7 ENSTSYP00000014082 ENSTSYP00000014082 MAP2K4 MAP2K4 AKT2 AKT2 PLCG2 PLCG2 PTK6 PTK6 RAC1 RAC1 ALOX5AP ALOX5AP ENSTSYP00000017214 ENSTSYP00000017214 MAPK12 MAPK12 SYK SYK MAP2K1 MAP2K1 GAB2 GAB2 PIK3R1 PIK3R1 JMJD7 JMJD7 MAP2K6 MAP2K6 NRAS NRAS PIK3R3 PIK3R3 LAT LAT MAPK8 MAPK8 MAPK11 MAPK11 MAPK13 MAPK13 LOC103251709 LOC103251709 TNF TNF MAPK3 MAPK3 VAV2 VAV2 PLA2G4A PLA2G4A ENSTSYP00000029618 ENSTSYP00000029618 PIK3CD PIK3CD AKT1 AKT1 MAPK9 MAPK9 LOC103271944 LOC103271944 LCP2 LCP2 MAPK1 MAPK1 RAC2 RAC2 GRB2 GRB2 SRMS SRMS PIK3CB PIK3CB FCER1G FCER1G
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HRASGTPase HRas isoform X6. (189 aa)
FCER1AHigh affinity immunoglobulin epsilon receptor subunit alpha. (258 aa)
LYNTyrosine-protein kinase. (512 aa)
VAV3Guanine nucleotide exchange factor VAV3-like. (514 aa)
SOS2Son of sevenless homolog 2 isoform X1. (1318 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
ALOX5Arachidonate 5-lipoxygenase isoform X1. (665 aa)
IL13Interleukin-13. (139 aa)
MS4A2High affinity immunoglobulin epsilon receptor subunit beta isoform X1. (243 aa)
PLA2G4BPhospholipase A2. (781 aa)
SOS1Son of sevenless homolog 1 isoform X2. (441 aa)
CSDE1Cold shock domain-containing protein E1 isoform X1. (842 aa)
PRKCAProtein kinase C. (614 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1302 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
KRASGTPase KRas isoform X1. (189 aa)
MAP2K3Dual specificity mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (347 aa)
MAPK10Mitogen-activated protein kinase. (473 aa)
PDPK13-phosphoinositide-dependent protein kinase 1. (554 aa)
PLA2G4FPhospholipase A2. (849 aa)
PLA2G4DPhospholipase A2. (806 aa)
RAF1RAF proto-oncogene serine/threonine-protein kinase isoform X1. (668 aa)
CSF2Granulocyte-macrophage colony-stimulating factor. (144 aa)
BTKTyrosine-protein kinase. (659 aa)
IL4Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family. (142 aa)
LOC103249868Cytosolic phospholipase A2 epsilon. (452 aa)
IL5Interleukin-5; Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells. (134 aa)
AKT3RAC-gamma serine/threonine-protein kinase; Belongs to the protein kinase superfamily. (419 aa)
INPP5DPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1. (1183 aa)
PLA2G4CCytosolic phospholipase A2 gamma. (520 aa)
RAC3Ras-related C3 botulinum toxin substrate 3. (192 aa)
FYNTyrosine-protein kinase. (537 aa)
ENSTSYP00000014000annotation not available (196 aa)
MAP2K7Dual specificity mitogen-activated protein kinase kinase 7. (414 aa)
ENSTSYP00000014082annotation not available (103 aa)
MAP2K4Dual specificity mitogen-activated protein kinase kinase 4 isoform X1; Belongs to the protein kinase superfamily. (387 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
PTK6Tyrosine-protein kinase. (450 aa)
RAC1Ras-related C3 botulinum toxin substrate 1. (212 aa)
ALOX5APArachidonate 5-lipoxygenase-activating protein. (161 aa)
ENSTSYP00000017214annotation not available (178 aa)
MAPK12Mitogen-activated protein kinase. (277 aa)
SYKTyrosine-protein kinase. (634 aa)
MAP2K1Dual specificity mitogen-activated protein kinase kinase 1. (381 aa)
GAB2GRB2-associated-binding protein 2. (651 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (612 aa)
JMJD7jmjC domain-containing protein 7. (308 aa)
MAP2K6LOW QUALITY PROTEIN: dual specificity mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (352 aa)
NRASGTPase NRas. (189 aa)
PIK3R3Phosphatidylinositol 3-kinase regulatory subunit gamma isoform X2. (461 aa)
LATLinker for activation of T cells. (258 aa)
MAPK8Mitogen-activated protein kinase. (384 aa)
MAPK11Mitogen-activated protein kinase. (255 aa)
MAPK13Mitogen-activated protein kinase. (365 aa)
LOC103251709Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (348 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (232 aa)
MAPK3Mitogen-activated protein kinase. (363 aa)
VAV2Guanine nucleotide exchange factor VAV2. (810 aa)
PLA2G4APhospholipase A2. (749 aa)
ENSTSYP00000029618annotation not available (173 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1063 aa)
AKT1Non-specific serine/threonine protein kinase. (393 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
LOC103271944Proto-oncogene vav. (147 aa)
LCP2Lymphocyte cytosolic protein 2. (532 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (363 aa)
RAC2Ras-related C3 botulinum toxin substrate 2 isoform X1. (192 aa)
GRB2Growth factor receptor-bound protein 2 isoform X1. (217 aa)
SRMSTyrosine-protein kinase. (424 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X2; Belongs to the PI3/PI4-kinase family. (1070 aa)
FCER1GHigh affinity immunoglobulin epsilon receptor subunit gamma. (86 aa)
Your Current Organism:
Carlito syrichta
NCBI taxonomy Id: 1868482
Other names: C. syrichta, Philippine tarsier, Tarsius syrichta
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