STRINGSTRING
PTRHD1 PTRHD1 MAPK3 MAPK3 LOC103252012 LOC103252012 LOC103253616 LOC103253616 ITPR3 ITPR3 LOC103253123 LOC103253123 PLCB2 PLCB2 ENSTSYP00000025340 ENSTSYP00000025340 ADCY7 ADCY7 LOC103249516 LOC103249516 GNG4 GNG4 GNG7 GNG7 ENSTSYP00000024385 ENSTSYP00000024385 GRIA1 GRIA1 PPP3CA PPP3CA JMJD7 JMJD7 CACNA1A CACNA1A GNB4 GNB4 GNG3 GNG3 ADCY6 ADCY6 LOC103263091 LOC103263091 GRM5 GRM5 GRK2 GRK2 GRM2 GRM2 GRIA2 GRIA2 PLCB3 PLCB3 PLD2 PLD2 GRIK2 GRIK2 SLC1A6 SLC1A6 SHANK3 SHANK3 GRIK5 GRIK5 GRIK3 GRIK3 GNB1 GNB1 LOC110595842 LOC110595842 SLC1A2 SLC1A2 CACNA1C CACNA1C PPP3R1 PPP3R1 ADCY4 ADCY4 PLA2G4C PLA2G4C PRKACA PRKACA DLG4 DLG4 LGSN LGSN GNB5 GNB5 SLC17A6 SLC17A6 PRKCB PRKCB ADCY8 ADCY8 SLC38A3 SLC38A3 GRIN3A GRIN3A LOC103249868 LOC103249868 ADCY3 ADCY3 ENSTSYP00000009157 ENSTSYP00000009157 GRIA4 GRIA4 DLGAP1 DLGAP1 PLCB1 PLCB1 ADCY9 ADCY9 GRIK1 GRIK1 GRIN2A GRIN2A PLCB4 PLCB4 SLC1A1 SLC1A1 KCNJ3 KCNJ3 GNG2 GNG2 GRM1 GRM1 GLS2 GLS2 GLS GLS PLA2G4D PLA2G4D PLA2G4F PLA2G4F SLC1A7 SLC1A7 LOC110594775 LOC110594775 SLC38A1 SLC38A1 GRIN2D GRIN2D LOC103271836 LOC103271836 GRM4 GRM4 HOMER1 HOMER1 PRKCA PRKCA PPP3CC PPP3CC HOMER2 HOMER2 PLA2G4B PLA2G4B GNGT1 GNGT1 GLUL GLUL SLC17A8 SLC17A8 ITPR2 ITPR2 PLD1 PLD1 ENSTSYP00000000513 ENSTSYP00000000513 GRM3 GRM3 PRKACB PRKACB ADCY2 ADCY2 LOC103255823 LOC103255823 GRIA3 GRIA3 GNB3 GNB3 PRKCG PRKCG SLC17A7 SLC17A7 ENSTSYP00000032829 ENSTSYP00000032829 PPP3CB PPP3CB ENSTSYP00000032761 ENSTSYP00000032761 SLC1A3 SLC1A3 GNAI2 GNAI2 GNAI3 GNAI3 GNB2 GNB2 ENSTSYP00000032347 ENSTSYP00000032347 SHANK2 SHANK2 MAPK1 MAPK1 GNG12 GNG12 GNAI1 GNAI1 ADCY5 ADCY5 SLC38A2 SLC38A2 GRIN2B GRIN2B GNG11 GNG11 GRK3 GRK3 GNG13 GNG13 GNGT2 GNGT2 CACNA1D CACNA1D GNAO1 GNAO1 GNG10 GNG10 PLA2G4A PLA2G4A ENSTSYP00000028505 ENSTSYP00000028505 TRPC1 TRPC1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
PTRHD1Putative peptidyl-tRNA hydrolase PTRHD1. (140 aa)
MAPK3Mitogen-activated protein kinase. (363 aa)
LOC103252012Glutamate receptor ionotropic, NMDA 1-like. (162 aa)
LOC103253616Metabotropic glutamate receptor 7. (182 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2677 aa)
LOC103253123Adenylate cyclase type 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (327 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1094 aa)
ENSTSYP00000025340annotation not available (215 aa)
ADCY7Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1071 aa)
LOC103249516Inositol 1,4,5-trisphosphate receptor type 1. (389 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
GNG7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
ENSTSYP00000024385annotation not available (65 aa)
GRIA1Glutamate receptor 1. (773 aa)
PPP3CASerine/threonine-protein phosphatase. (521 aa)
JMJD7jmjC domain-containing protein 7. (308 aa)
CACNA1AVoltage-dependent P/Q-type calcium channel subunit alpha-1A. (1979 aa)
GNB4Guanine nucleotide-binding protein subunit beta-4. (340 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
ADCY6Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1166 aa)
LOC103263091Adenylate cyclase type 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (293 aa)
GRM5Metabotropic glutamate receptor 5. (867 aa)
GRK2G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (621 aa)
GRM2Metabotropic glutamate receptor 2 isoform X1. (872 aa)
GRIA2Glutamate receptor 2 isoform X4. (883 aa)
PLCB3Phosphoinositide phospholipase C. (828 aa)
PLD2Phospholipase. (934 aa)
GRIK2Glutamate receptor ionotropic, kainate 2. (870 aa)
SLC1A6Amino acid transporter. (564 aa)
SHANK3SH3 and multiple ankyrin repeat domains protein 3. (1282 aa)
GRIK5Glutamate receptor ionotropic, kainate 5. (981 aa)
GRIK3Glutamate receptor ionotropic, kainate 3. (926 aa)
GNB1Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 isoform X1. (340 aa)
LOC110595842Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (63 aa)
SLC1A2Amino acid transporter. (565 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2045 aa)
PPP3R1Calcineurin subunit B type 1. (169 aa)
ADCY4Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
PLA2G4CCytosolic phospholipase A2 gamma. (520 aa)
PRKACAcAMP-dependent protein kinase catalytic subunit alpha; Belongs to the protein kinase superfamily. (343 aa)
DLG4Disks large homolog 4 isoform X1; Belongs to the MAGUK family. (765 aa)
LGSNLOW QUALITY PROTEIN: lengsin; Belongs to the glutamine synthetase family. (503 aa)
GNB5Guanine nucleotide-binding protein subunit beta-5. (396 aa)
SLC17A6Vesicular glutamate transporter 2. (582 aa)
PRKCBNon-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (531 aa)
ADCY8Adenylate cyclase type 8; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (931 aa)
SLC38A3Sodium-coupled neutral amino acid transporter 3. (504 aa)
GRIN3AGlutamate receptor ionotropic, NMDA 3A; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1115 aa)
LOC103249868Cytosolic phospholipase A2 epsilon. (452 aa)
ADCY3Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1145 aa)
ENSTSYP00000009157annotation not available (65 aa)
GRIA4Glutamate receptor 4 isoform X1. (902 aa)
DLGAP1Disks large-associated protein 1 isoform X2. (977 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1135 aa)
ADCY9Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa)
GRIK1Glutamate receptor ionotropic, kainate 1; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (583 aa)
GRIN2AGlutamate receptor ionotropic, NMDA 2A; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1144 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1194 aa)
SLC1A1Amino acid transporter. (524 aa)
KCNJ3G protein-activated inward rectifier potassium channel 1 isoform X1. (502 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (107 aa)
GRM1LOW QUALITY PROTEIN: metabotropic glutamate receptor 1-like. (715 aa)
GLS2Glutaminase liver isoform, mitochondrial isoform X1. (591 aa)
GLSGlutaminase kidney isoform, mitochondrial. (669 aa)
PLA2G4DPhospholipase A2. (806 aa)
PLA2G4FPhospholipase A2. (849 aa)
SLC1A7Amino acid transporter. (560 aa)
LOC110594775Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
SLC38A1Sodium-coupled neutral amino acid transporter 1 isoform X2. (502 aa)
GRIN2DGlutamate receptor ionotropic, NMDA 2D; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (766 aa)
LOC103271836Metabotropic glutamate receptor 8. (416 aa)
GRM4Metabotropic glutamate receptor 4. (904 aa)
HOMER1Homer protein homolog 1. (366 aa)
PRKCAProtein kinase C. (614 aa)
PPP3CCSerine/threonine-protein phosphatase. (514 aa)
HOMER2Homer protein homolog 2. (359 aa)
PLA2G4BPhospholipase A2. (781 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
GLULGlutamine synthetase. (380 aa)
SLC17A8Vesicular glutamate transporter 3. (589 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2701 aa)
PLD1Phospholipase. (1075 aa)
ENSTSYP00000000513annotation not available (297 aa)
GRM3Metabotropic glutamate receptor 3. (747 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily. (398 aa)
ADCY2Adenylate cyclase type 2. (955 aa)
LOC103255823Guanine nucleotide-binding protein G(S) subunit alpha isoform X2. (361 aa)
GRIA3Glutamate receptor 3. (894 aa)
GNB3Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 isoform X1. (340 aa)
PRKCGProtein kinase C. (634 aa)
SLC17A7Vesicular glutamate transporter 1. (469 aa)
ENSTSYP00000032829annotation not available (586 aa)
PPP3CBSerine/threonine-protein phosphatase. (525 aa)
ENSTSYP00000032761annotation not available (68 aa)
SLC1A3Amino acid transporter. (542 aa)
GNAI2Guanine nucleotide-binding protein G(I) subunit alpha-2 isoform X1. (355 aa)
GNAI3Guanine nucleotide-binding protein G(K) subunit alpha. (354 aa)
GNB2Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 isoform X3. (321 aa)
ENSTSYP00000032347annotation not available (154 aa)
SHANK2SH3 and multiple ankyrin repeat domains protein 2. (1158 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (363 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
GNAI1Guanine nucleotide-binding protein G(I) subunit alpha-1. (354 aa)
ADCY5Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (915 aa)
SLC38A2Sodium-coupled neutral amino acid transporter 2 isoform X1. (505 aa)
GRIN2BGlutamate receptor ionotropic, NMDA 2B. (1347 aa)
GNG11Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
GRK3G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (609 aa)
GNG13Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13. (67 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2028 aa)
GNAO1Guanine nucleotide-binding protein G(O) subunit alpha. (314 aa)
GNG10Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
PLA2G4APhospholipase A2. (749 aa)
ENSTSYP00000028505annotation not available (242 aa)
TRPC1Short transient receptor potential channel 1-like. (647 aa)
Your Current Organism:
Carlito syrichta
NCBI taxonomy Id: 1868482
Other names: C. syrichta, Philippine tarsier, Tarsius syrichta
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