STRINGSTRING
DIAPH2 DIAPH2 PIP4K2B PIP4K2B ENSTSYP00000033115 ENSTSYP00000033115 ARHGEF6 ARHGEF6 SSH3 SSH3 EZR EZR RAC2 RAC2 MSN MSN MAPK1 MAPK1 GEM GEM RRAD RRAD ENSTSYP00000026980 ENSTSYP00000026980 MYLK2 MYLK2 ARHGEF12 ARHGEF12 PAK6 PAK6 ENSTSYP00000027501 ENSTSYP00000027501 ABI2 ABI2 ENSTSYP00000027873 ENSTSYP00000027873 MAPK3 MAPK3 ENSTSYP00000027924 ENSTSYP00000027924 VAV2 VAV2 DIAPH3 DIAPH3 PPP1CA PPP1CA ARHGEF1 ARHGEF1 BDKRB2 BDKRB2 ENSTSYP00000028865 ENSTSYP00000028865 ENSTSYP00000028924 ENSTSYP00000028924 PDGFRB PDGFRB MYH10 MYH10 ITGA2B ITGA2B LOC103252352 LOC103252352 LOC103256465 LOC103256465 ENSTSYP00000029435 ENSTSYP00000029435 ARAF ARAF ENSTSYP00000029618 ENSTSYP00000029618 IQGAP1 IQGAP1 ENSTSYP00000029639 ENSTSYP00000029639 LOC103269764 LOC103269764 PDGFB PDGFB PIK3CD PIK3CD ENSTSYP00000029868 ENSTSYP00000029868 LOC103252205 LOC103252205 ENSTSYP00000030021 ENSTSYP00000030021 ENSTSYP00000030184 ENSTSYP00000030184 ENSTSYP00000030193 ENSTSYP00000030193 LOC103253501 LOC103253501 ACTN1 ACTN1 PFN1-2 PFN1-2 ITGA5 ITGA5 ENSTSYP00000031147 ENSTSYP00000031147 ENSTSYP00000031155 ENSTSYP00000031155 RDX RDX LOC103252824 LOC103252824 ENSTSYP00000031441 ENSTSYP00000031441 GOLGA2 GOLGA2 CDC42 CDC42 GNG12 GNG12 LOC103271944 LOC103271944 ENSTSYP00000031672 ENSTSYP00000031672 ENSTSYP00000031767 ENSTSYP00000031767 ENSTSYP00000031889 ENSTSYP00000031889 MYLK MYLK VCL VCL FGF16 FGF16 ITGA9 ITGA9 VAV3 VAV3 ENSTSYP00000000627 ENSTSYP00000000627 ENSTSYP00000000780 ENSTSYP00000000780 SOS2 SOS2 ARPC2 ARPC2 CCDC125 CCDC125 MYL5 MYL5 LOC103256300 LOC103256300 ENSTSYP00000002295 ENSTSYP00000002295 TIAM1 TIAM1 ARPC3 ARPC3 LOC103254094 LOC103254094 PIP5K1B-2 PIP5K1B-2 ARPC1A ARPC1A SOS1 SOS1 PAK3 PAK3 HRAS HRAS CSDE1 CSDE1 TUBGCP5 TUBGCP5 RHOA-2 RHOA-2 LOC103251709 LOC103251709 ENSTSYP00000026390 ENSTSYP00000026390 LPAR1 LPAR1 DIAPH1 DIAPH1 ITGB7 ITGB7 NEDD9 NEDD9 GNA12 GNA12 GNA13 GNA13 FGF18 FGF18 ENSTSYP00000025467 ENSTSYP00000025467 PIK3R3 PIK3R3 ENSTSYP00000025399 ENSTSYP00000025399 GIT1 GIT1 FGFR3 FGFR3 PTK2 PTK2 LIMK1 LIMK1 NRAS NRAS ENSTSYP00000024855 ENSTSYP00000024855 LOC103266055 LOC103266055 LOC103268048 LOC103268048 APC APC MYH9 MYH9 RHOA RHOA FGF21 FGF21 ENSTSYP00000024401 ENSTSYP00000024401 ENSTSYP00000024385 ENSTSYP00000024385 LOC103255576 LOC103255576 ENSTSYP00000024356 ENSTSYP00000024356 ENSTSYP00000024176 ENSTSYP00000024176 ITGB4 ITGB4 SLC9A1 SLC9A1 SSH2 SSH2 ENSTSYP00000023933 ENSTSYP00000023933 CYFIP1 CYFIP1 PFN1 PFN1 PPP1R12A PPP1R12A INSRR INSRR PPP1R12C PPP1R12C TGFB1I1 TGFB1I1 ENSTSYP00000023395 ENSTSYP00000023395 ZNF408 ZNF408 ENSTSYP00000022866 ENSTSYP00000022866 CHRM4 CHRM4 SRC SRC ENSTSYP00000022482 ENSTSYP00000022482 ITGA11 ITGA11 BAIAP2 BAIAP2 FGFR1 FGFR1 FGF9 FGF9 ITGA7 ITGA7 ITGAV ITGAV ENSTSYP00000021813 ENSTSYP00000021813 LPAR2 LPAR2 FGF10 FGF10 LOC103256301 LOC103256301 MYL7 MYL7 ARHGAP35 ARHGAP35 PIK3R1 PIK3R1 MRAS MRAS LOC103255041 LOC103255041 SPATA13 SPATA13 ITGA10 ITGA10 FGF17 FGF17 FGF20-2 FGF20-2 MYL10 MYL10 FGF20 FGF20 ARHGEF7 ARHGEF7 ENSTSYP00000020233 ENSTSYP00000020233 PIP5K1C PIP5K1C VIL1 VIL1 LOC103267910 LOC103267910 MYL2 MYL2 ENSTSYP00000019317 ENSTSYP00000019317 ENSTSYP00000019285 ENSTSYP00000019285 NCKAP1 NCKAP1 ROCK2 ROCK2 ENSTSYP00000018893 ENSTSYP00000018893 FGF1 FGF1 LOC103270825 LOC103270825 ENSTSYP00000018500 ENSTSYP00000018500 MAP2K1 MAP2K1 WASL WASL RRAS2 RRAS2 LOC103268632 LOC103268632 ARPC1B ARPC1B ITGB2 ITGB2 CXCR4 CXCR4 ENSTSYP00000017214 ENSTSYP00000017214 ENSTSYP00000016777 ENSTSYP00000016777 LOC103250564 LOC103250564 ENSTSYP00000016704 ENSTSYP00000016704 RAC1 RAC1 ZSCAN2 ZSCAN2 AVIL AVIL PIP4K2C PIP4K2C ROCK1 ROCK1 ENSTSYP00000016210 ENSTSYP00000016210 RHOC RHOC FGF7 FGF7 ENSTSYP00000016065 ENSTSYP00000016065 LRRC45 LRRC45 ENSTSYP00000015595 ENSTSYP00000015595 ENSTSYP00000015465 ENSTSYP00000015465 LOC103269809 LOC103269809 FGF3 FGF3 MYL12A MYL12A CYFIP2 CYFIP2 CFL1 CFL1 VILL VILL ENSTSYP00000014712 ENSTSYP00000014712 SSH1 SSH1 FGF6 FGF6 LOC103272116 LOC103272116 ENSTSYP00000014331 ENSTSYP00000014331 ENSTSYP00000014307 ENSTSYP00000014307 PPP1R12B PPP1R12B PAK4 PAK4 ENSTSYP00000013967 ENSTSYP00000013967 ARPC5 ARPC5 RAC3 RAC3 PIP4K2A PIP4K2A FGF5 FGF5 ITGB5 ITGB5 WASF1 WASF1 FGD2 FGD2 PIKFYVE PIKFYVE NCKAP1L NCKAP1L ITGA8 ITGA8 TIAM2 TIAM2 PDGFD PDGFD BCAR1 BCAR1 RRAS RRAS ARHGEF9 ARHGEF9 CHRM2 CHRM2 PAK2 PAK2 ITGAM ITGAM CHRM1 CHRM1 ITGAL ITGAL PDGFC PDGFC ZNF774 ZNF774 MYLK4 MYLK4 MYLPF MYLPF LOC103251683 LOC103251683 ITGAD ITGAD ITGAX ITGAX FGFR2 FGFR2 PPP1CB PPP1CB LPXN LPXN ARPC5L ARPC5L IQGAP2 IQGAP2 ACTL8 ACTL8 EGF EGF ITGB1 ITGB1 BRAF BRAF KNG1 KNG1 LOC103259657 LOC103259657 ITGA2 ITGA2 FN1 FN1 ITGA4 ITGA4 ITGAE ITGAE GALK2 GALK2 SCIN SCIN RAF1 RAF1 ITGA6 ITGA6 FGD3 FGD3 F2 F2 ACTL7B ACTL7B CFL2 CFL2 EGFR EGFR CAPG CAPG MYLK3 MYLK3 ITGB6 ITGB6 PFN4 PFN4 FGD1 FGD1 LOC103277367 LOC103277367 ITGB8 ITGB8 ITGA1 ITGA1 PIP5K1A PIP5K1A PAK1 PAK1 FGD4 FGD4 PAK5 PAK5 PXN PXN PDGFRA PDGFRA KRAS KRAS GSN GSN ENSTSYP00000004023 ENSTSYP00000004023 PIK3CA PIK3CA LOC103256188 LOC103256188 TMSB10 TMSB10 ENSTSYP00000034760 ENSTSYP00000034760 CRKL CRKL WASF2 WASF2 PIK3CB PIK3CB ARPC4 ARPC4 ENSTSYP00000034200 ENSTSYP00000034200 ANKRD13D ANKRD13D LIMK2 LIMK2 IQGAP3 IQGAP3 ENSTSYP00000033676 ENSTSYP00000033676 REM1 REM1 CRK CRK ACTN4 ACTN4 PDGFA PDGFA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DIAPH2Protein diaphanous homolog 2. (905 aa)
PIP4K2BPhosphatidylinositol 5-phosphate 4-kinase type-2 beta. (363 aa)
ENSTSYP00000033115annotation not available (96 aa)
ARHGEF6Rho guanine nucleotide exchange factor 6 isoform X1. (777 aa)
SSH3Protein phosphatase Slingshot homolog 3. (653 aa)
EZREzrin isoform X3. (598 aa)
RAC2Ras-related C3 botulinum toxin substrate 2 isoform X1. (192 aa)
MSNMoesin. (578 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (363 aa)
GEMGTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (296 aa)
RRADGTP-binding protein RAD. (275 aa)
ENSTSYP00000026980annotation not available (40 aa)
MYLK2Myosin light chain kinase 2, skeletal/cardiac muscle. (559 aa)
ARHGEF12Rho guanine nucleotide exchange factor 12. (124 aa)
PAK6Non-specific serine/threonine protein kinase. (681 aa)
ENSTSYP00000027501annotation not available (135 aa)
ABI2Abl interactor 2 isoform X1. (513 aa)
ENSTSYP00000027873annotation not available (243 aa)
MAPK3Mitogen-activated protein kinase. (363 aa)
ENSTSYP00000027924annotation not available (51 aa)
VAV2Guanine nucleotide exchange factor VAV2. (810 aa)
DIAPH3Protein diaphanous homolog 3 isoform X1. (1113 aa)
PPP1CASerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (322 aa)
ARHGEF1Rho guanine nucleotide exchange factor 1. (966 aa)
BDKRB2B2 bradykinin receptor; Belongs to the G-protein coupled receptor 1 family. (392 aa)
ENSTSYP00000028865annotation not available (429 aa)
ENSTSYP00000028924annotation not available (322 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1105 aa)
MYH10Myosin-10 isoform X2; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2007 aa)
ITGA2BIntegrin alpha-IIb; Belongs to the integrin alpha chain family. (851 aa)
LOC103252352Myosin-14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (547 aa)
LOC103256465Ras GTPase-activating-like protein IQGAP2. (297 aa)
ENSTSYP00000029435annotation not available (271 aa)
ARAFSerine/threonine-protein kinase A-Raf isoform X1. (611 aa)
ENSTSYP00000029618annotation not available (173 aa)
IQGAP1Ras GTPase-activating-like protein IQGAP1. (1657 aa)
ENSTSYP00000029639annotation not available (166 aa)
LOC103269764Stromal cell-derived factor 1-like; Belongs to the intercrine alpha (chemokine CxC) family. (119 aa)
PDGFBPlatelet-derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (229 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1063 aa)
ENSTSYP00000029868annotation not available (246 aa)
LOC103252205Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (337 aa)
ENSTSYP00000030021annotation not available (162 aa)
ENSTSYP00000030184annotation not available (260 aa)
ENSTSYP00000030193annotation not available (164 aa)
LOC103253501Guanine nucleotide exchange factor VAV3-like. (209 aa)
ACTN1Alpha-actinin-1 isoform X1. (888 aa)
PFN1-2Profilin; Belongs to the profilin family. (140 aa)
ITGA5Integrin alpha-5; Belongs to the integrin alpha chain family. (1053 aa)
ENSTSYP00000031147annotation not available (244 aa)
ENSTSYP00000031155annotation not available (169 aa)
RDXRadixin isoform X1. (604 aa)
LOC103252824Nucleophosmin isoform X1. (294 aa)
ENSTSYP00000031441annotation not available (131 aa)
GOLGA2Golgin subfamily A member 2. (999 aa)
CDC42Cell division control protein 42 homolog. (191 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
LOC103271944Proto-oncogene vav. (147 aa)
ENSTSYP00000031672annotation not available (349 aa)
ENSTSYP00000031767annotation not available (75 aa)
ENSTSYP00000031889annotation not available (273 aa)
MYLKMyosin light chain kinase, smooth muscle isoform X1. (1917 aa)
VCLVinculin. (1122 aa)
FGF16Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (198 aa)
ITGA9Integrin alpha-9; Belongs to the integrin alpha chain family. (563 aa)
VAV3Guanine nucleotide exchange factor VAV3-like. (514 aa)
ENSTSYP00000000627annotation not available (167 aa)
ENSTSYP00000000780ENAH actin regulator. (783 aa)
SOS2Son of sevenless homolog 2 isoform X1. (1318 aa)
ARPC2Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (300 aa)
CCDC125Coiled-coil domain-containing protein 125. (273 aa)
MYL5Myosin light chain 5. (173 aa)
LOC103256300Arylacetamide deacetylase-like. (395 aa)
ENSTSYP00000002295annotation not available (173 aa)
TIAM1T-lymphoma invasion and metastasis-inducing protein 1. (1592 aa)
ARPC3Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (178 aa)
LOC103254094Dedicator of cytokinesis protein 1-like; Belongs to the DOCK family. (696 aa)
PIP5K1B-2Phosphatidylinositol 4-phosphate 5-kinase type-1 beta. (257 aa)
ARPC1AActin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (370 aa)
SOS1Son of sevenless homolog 1 isoform X2. (441 aa)
PAK3Serine/threonine-protein kinase PAK 3 isoform X1. (580 aa)
HRASGTPase HRas isoform X6. (189 aa)
CSDE1Cold shock domain-containing protein E1 isoform X1. (842 aa)
TUBGCP5Gamma-tubulin complex component; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome; Belongs to the TUBGCP family. (1024 aa)
RHOA-2Transforming protein RhoA isoform X1. (193 aa)
LOC103251709Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (348 aa)
ENSTSYP00000026390annotation not available (153 aa)
LPAR1Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family. (297 aa)
DIAPH1Protein diaphanous homolog 1. (1236 aa)
ITGB7Integrin beta; Belongs to the integrin beta chain family. (699 aa)
NEDD9Enhancer of filamentation 1. (834 aa)
GNA12Guanine nucleotide-binding protein subunit alpha-12. (304 aa)
GNA13Guanine nucleotide-binding protein subunit alpha-13. (282 aa)
FGF18Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (184 aa)
ENSTSYP00000025467annotation not available (44 aa)
PIK3R3Phosphatidylinositol 3-kinase regulatory subunit gamma isoform X2. (461 aa)
ENSTSYP00000025399annotation not available (44 aa)
GIT1ARF GTPase-activating protein GIT1 isoform X1. (770 aa)
FGFR3Fibroblast growth factor receptor. (745 aa)
PTK2Focal adhesion kinase 1 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1096 aa)
LIMK1LIM domain kinase 1 isoform X1. (663 aa)
NRASGTPase NRas. (189 aa)
ENSTSYP00000024855annotation not available (51 aa)
LOC103266055Protein diaphanous homolog 2-like. (122 aa)
LOC103268048Profilin; Belongs to the profilin family. (106 aa)
APCAdenomatous polyposis coli protein isoform X2. (2844 aa)
MYH9Myosin-9 isoform X1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1952 aa)
RHOATransforming protein RhoA isoform X7. (81 aa)
FGF21Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
ENSTSYP00000024401annotation not available (186 aa)
ENSTSYP00000024385annotation not available (65 aa)
LOC103255576Myosin regulatory light chain 12B-like isoform X2. (161 aa)
ENSTSYP00000024356annotation not available (326 aa)
ENSTSYP00000024176annotation not available (44 aa)
ITGB4Integrin beta. (1638 aa)
SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (811 aa)
SSH2Protein phosphatase Slingshot homolog 2. (1448 aa)
ENSTSYP00000023933annotation not available (330 aa)
CYFIP1Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1253 aa)
PFN1Profilin; Belongs to the profilin family. (126 aa)
PPP1R12AProtein phosphatase 1 regulatory subunit. (1030 aa)
INSRRTyrosine-protein kinase receptor. (1284 aa)
PPP1R12CLOW QUALITY PROTEIN: protein phosphatase 1 regulatory subunit 12C. (578 aa)
TGFB1I1Transforming growth factor beta-1-induced transcript 1 protein; Belongs to the paxillin family. (456 aa)
ENSTSYP00000023395annotation not available (77 aa)
ZNF408Zinc finger protein 408. (697 aa)
ENSTSYP00000022866annotation not available (318 aa)
CHRM4Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (478 aa)
SRCTyrosine-protein kinase. (542 aa)
ENSTSYP00000022482annotation not available (178 aa)
ITGA11Integrin alpha-11; Belongs to the integrin alpha chain family. (1171 aa)
BAIAP2Brain-specific angiogenesis inhibitor 1-associated protein 2 isoform X4. (553 aa)
FGFR1Fibroblast growth factor receptor. (832 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (146 aa)
ITGA7Integrin alpha-7; Belongs to the integrin alpha chain family. (1178 aa)
ITGAVIntegrin alpha-V; Belongs to the integrin alpha chain family. (1041 aa)
ENSTSYP00000021813annotation not available (294 aa)
LPAR2Lysophosphatidic acid receptor 2; Belongs to the G-protein coupled receptor 1 family. (351 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
LOC103256301Arylacetamide deacetylase. (399 aa)
MYL7Myosin regulatory light chain 2, atrial isoform isoform X1. (175 aa)
ARHGAP35Rho GTPase-activating protein 35. (1282 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (612 aa)
MRASRas-related protein M-Ras. (174 aa)
LOC103255041Myosin-11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2012 aa)
SPATA13LOW QUALITY PROTEIN: spermatogenesis-associated protein 13. (652 aa)
ITGA10Integrin alpha-10 isoform X1; Belongs to the integrin alpha chain family. (1167 aa)
FGF17Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (205 aa)
FGF20-2Fibroblast growth factor 20. (75 aa)
MYL10Myosin regulatory light chain 10. (181 aa)
FGF20Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (115 aa)
ARHGEF7Rho guanine nucleotide exchange factor 7 isoform X1. (705 aa)
ENSTSYP00000020233annotation not available (371 aa)
PIP5K1CPhosphatidylinositol 4-phosphate 5-kinase type-1 gamma. (698 aa)
VIL1Villin-1. (828 aa)
LOC103267910Fibroblast growth factor receptor 2-like. (208 aa)
MYL2Myosin regulatory light chain 2, ventricular/cardiac muscle isoform. (136 aa)
ENSTSYP00000019317annotation not available (171 aa)
ENSTSYP00000019285annotation not available (346 aa)
NCKAP1Nck-associated protein 1. (1133 aa)
ROCK2Rho-associated protein kinase 2 isoform X1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1376 aa)
ENSTSYP00000018893annotation not available (163 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
LOC103270825Protein BRICK1 isoform X4. (75 aa)
ENSTSYP00000018500annotation not available (73 aa)
MAP2K1Dual specificity mitogen-activated protein kinase kinase 1. (381 aa)
WASLNeural Wiskott-Aldrich syndrome protein. (504 aa)
RRAS2Ras-related protein R-Ras2. (204 aa)
LOC103268632Rho guanine nucleotide exchange factor 4-like. (142 aa)
ARPC1BActin-related protein 2/3 complex subunit 1B. (303 aa)
ITGB2Integrin beta. (769 aa)
CXCR4C-X-C chemokine receptor type 4 isoform X3; Belongs to the G-protein coupled receptor 1 family. (355 aa)
ENSTSYP00000017214annotation not available (178 aa)
ENSTSYP00000016777annotation not available (44 aa)
LOC103250564Integrin beta; Belongs to the integrin beta chain family. (418 aa)
ENSTSYP00000016704annotation not available (357 aa)
RAC1Ras-related C3 botulinum toxin substrate 1. (212 aa)
ZSCAN2Zinc finger and SCAN domain-containing protein 2 isoform X1. (615 aa)
AVILAdvillin. (819 aa)
PIP4K2CPhosphatidylinositol 5-phosphate 4-kinase type-2 gamma isoform X1. (421 aa)
ROCK1Rho-associated protein kinase 1 isoform X1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1367 aa)
ENSTSYP00000016210annotation not available (141 aa)
RHOCRho-related GTP-binding protein RhoC isoform X2. (193 aa)
FGF7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
ENSTSYP00000016065annotation not available (140 aa)
LRRC45Leucine-rich repeat-containing protein 45. (670 aa)
ENSTSYP00000015595annotation not available (270 aa)
ENSTSYP00000015465annotation not available (282 aa)
LOC103269809Thymosin beta; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Belongs to the thymosin beta family. (69 aa)
FGF3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (172 aa)
MYL12AMyosin regulatory light polypeptide 9 isoform X2. (172 aa)
CYFIP2Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1278 aa)
CFL1Cofilin-1 isoform X1; Belongs to the actin-binding proteins ADF family. (195 aa)
VILLVillin-like protein. (856 aa)
ENSTSYP00000014712annotation not available (232 aa)
SSH1Protein phosphatase Slingshot homolog 1. (1044 aa)
FGF6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
LOC103272116Thymosin beta; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Belongs to the thymosin beta family. (50 aa)
ENSTSYP00000014331annotation not available (108 aa)
ENSTSYP00000014307annotation not available (276 aa)
PPP1R12BProtein phosphatase 1 regulatory subunit 12B. (886 aa)
PAK4Non-specific serine/threonine protein kinase. (567 aa)
ENSTSYP00000013967annotation not available (167 aa)
ARPC5Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (151 aa)
RAC3Ras-related C3 botulinum toxin substrate 3. (192 aa)
PIP4K2APhosphatidylinositol 5-phosphate 4-kinase type-2 alpha. (386 aa)
FGF5Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (268 aa)
ITGB5Integrin beta; Belongs to the integrin beta chain family. (922 aa)
WASF1wiskott-Aldrich syndrome protein family member 1. (560 aa)
FGD2FYVE, RhoGEF and PH domain-containing protein 2. (626 aa)
PIKFYVE1-phosphatidylinositol 3-phosphate 5-kinase. (2099 aa)
NCKAP1LNck-associated protein 1-like. (1128 aa)
ITGA8Integrin alpha-8; Belongs to the integrin alpha chain family. (1060 aa)
TIAM2T-lymphoma invasion and metastasis-inducing protein 2 isoform X1. (1723 aa)
PDGFDPlatelet-derived growth factor D. (370 aa)
BCAR1Breast cancer anti-estrogen resistance protein 1. (871 aa)
RRASRas-related protein R-Ras. (218 aa)
ARHGEF9Rho guanine nucleotide exchange factor 9. (272 aa)
CHRM2Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (466 aa)
PAK2Non-specific serine/threonine protein kinase. (524 aa)
ITGAMIntegrin alpha-M; Belongs to the integrin alpha chain family. (1152 aa)
CHRM1Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (460 aa)
ITGALIntegrin alpha-L; Belongs to the integrin alpha chain family. (1167 aa)
PDGFCPlatelet-derived growth factor C isoform X1; Belongs to the PDGF/VEGF growth factor family. (345 aa)
ZNF774LOW QUALITY PROTEIN: zinc finger protein 774. (463 aa)
MYLK4Myosin light chain kinase family member 4; Belongs to the protein kinase superfamily. (389 aa)
MYLPFMyosin regulatory light chain 2, skeletal muscle isoform. (172 aa)
LOC103251683Insulin-like; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (99 aa)
ITGADIntegrin alpha-D isoform X2; Belongs to the integrin alpha chain family. (1161 aa)
ITGAXIntegrin alpha-X; Belongs to the integrin alpha chain family. (1149 aa)
FGFR2Fibroblast growth factor receptor 2 isoform X1. (615 aa)
PPP1CBSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (313 aa)
LPXNLeupaxin; Belongs to the paxillin family. (391 aa)
ARPC5LActin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (153 aa)
IQGAP2Ras GTPase-activating-like protein IQGAP2 isoform X3. (1070 aa)
ACTL8LOW QUALITY PROTEIN: actin-like protein 8; Belongs to the actin family. (366 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1167 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (801 aa)
BRAFSerine/threonine-protein kinase B-raf. (760 aa)
KNG1Kininogen-1 isoform X1. (645 aa)
LOC103259657Profilin; Belongs to the profilin family. (156 aa)
ITGA2LOW QUALITY PROTEIN: integrin alpha-2; Belongs to the integrin alpha chain family. (1175 aa)
FN1Fibronectin isoform X2. (2450 aa)
ITGA4Integrin alpha-4; Belongs to the integrin alpha chain family. (1033 aa)
ITGAEIntegrin alpha-E; Belongs to the integrin alpha chain family. (1173 aa)
GALK2N-acetylgalactosamine kinase isoform X1. (458 aa)
SCINAdseverin. (680 aa)
RAF1RAF proto-oncogene serine/threonine-protein kinase isoform X1. (668 aa)
ITGA6Integrin alpha-6 isoform X1; Belongs to the integrin alpha chain family. (1130 aa)
FGD3FYVE, RhoGEF and PH domain-containing protein 3. (710 aa)
F2Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (623 aa)
ACTL7BLOW QUALITY PROTEIN: actin-like protein 7B; Belongs to the actin family. (366 aa)
CFL2Cofilin-2; Belongs to the actin-binding proteins ADF family. (166 aa)
EGFRReceptor protein-tyrosine kinase. (1180 aa)
CAPGMacrophage-capping protein isoform X1. (348 aa)
MYLK3Myosin light chain kinase 3. (477 aa)
ITGB6Integrin beta; Belongs to the integrin beta chain family. (788 aa)
PFN4Profilin; Belongs to the profilin family. (129 aa)
FGD1FYVE, RhoGEF and PH domain-containing protein 1. (964 aa)
LOC103277367Myosin regulatory light chain 12B. (172 aa)
ITGB8Integrin beta; Belongs to the integrin beta chain family. (768 aa)
ITGA1Integrin alpha-1; Belongs to the integrin alpha chain family. (971 aa)
PIP5K1APhosphatidylinositol 4-phosphate 5-kinase type-1 alpha isoform X2. (581 aa)
PAK1Non-specific serine/threonine protein kinase. (545 aa)
FGD4FYVE, RhoGEF and PH domain-containing protein 4 isoform X1. (901 aa)
PAK5Non-specific serine/threonine protein kinase. (719 aa)
PXNLOW QUALITY PROTEIN: paxillin. (1079 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1088 aa)
KRASGTPase KRas isoform X1. (189 aa)
GSNGelsolin isoform X1. (777 aa)
ENSTSYP00000004023annotation not available (65 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
LOC103256188Integrin alpha-9-like. (557 aa)
TMSB10Thymosin beta; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Belongs to the thymosin beta family. (44 aa)
ENSTSYP00000034760annotation not available (286 aa)
CRKLCrk-like protein. (303 aa)
WASF2wiskott-Aldrich syndrome protein family member 2 isoform X1. (497 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X2; Belongs to the PI3/PI4-kinase family. (1070 aa)
ARPC4Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family. (211 aa)
ENSTSYP00000034200annotation not available (134 aa)
ANKRD13DAnkyrin repeat domain-containing protein 13D. (605 aa)
LIMK2LIM domain kinase 2 isoform X1. (645 aa)
IQGAP3Ras GTPase-activating-like protein IQGAP3. (1632 aa)
ENSTSYP00000033676annotation not available (300 aa)
REM1GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (331 aa)
CRKAdapter molecule crk isoform X1. (304 aa)
ACTN4Alpha-actinin-4 isoform X2. (880 aa)
PDGFAPlatelet-derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. (202 aa)
Your Current Organism:
Carlito syrichta
NCBI taxonomy Id: 1868482
Other names: C. syrichta, Philippine tarsier, Tarsius syrichta
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