51 items (Carlito syrichta) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC103255823	Guanine nucleotide-binding protein G(S) subunit alpha isoform X2. (361 aa)
	ADCY2	Adenylate cyclase type 2. (955 aa)
	PRKACB	cAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily. (398 aa)
	ALOX5	Arachidonate 5-lipoxygenase isoform X1. (665 aa)
	IGF1R	Tyrosine-protein kinase receptor. (1335 aa)
	FSHR	Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. (620 aa)
	PLA2G4B	Phospholipase A2. (781 aa)
	BMP6	Bone morphogenetic protein 6. (513 aa)
	HSD17B7	3-keto-steroid reductase isoform X1. (306 aa)
	STAR	Steroidogenic acute regulatory protein, mitochondrial; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone. (285 aa)
	CGA	Glycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. (120 aa)
	PLA2G4F	Phospholipase A2. (849 aa)
	PLA2G4D	Phospholipase A2. (806 aa)
	CYP2J2	Cytochrome P450 2J2; Belongs to the cytochrome P450 family. (502 aa)
	CYP19A1	Aromatase; Belongs to the cytochrome P450 family. (503 aa)
	LHCGR	Lutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (702 aa)
	LOC103261880	Prostaglandin F synthase 1-like. (324 aa)
	ADCY9	Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa)
	PTRHD1	Putative peptidyl-tRNA hydrolase PTRHD1. (140 aa)
	ADCY3	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1145 aa)
	LOC103249868	Cytosolic phospholipase A2 epsilon. (452 aa)
	LOC103251683	Insulin-like; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (99 aa)
	ADCY8	Adenylate cyclase type 8; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (931 aa)
	FSHB	Follitropin subunit beta. (129 aa)
	LOC103261879	Prostaglandin F synthase 1-like. (324 aa)
	PTGS2	Prostaglandin G/H synthase 2. (604 aa)
	HSD17B2	Estradiol 17-beta-dehydrogenase 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (268 aa)
	PRKACA	cAMP-dependent protein kinase catalytic subunit alpha; Belongs to the protein kinase superfamily. (343 aa)
	PLA2G4C	Cytosolic phospholipase A2 gamma. (520 aa)
	ADCY4	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
	LOC103273277	Cytochrome P450 2J5-like. (282 aa)
	SCARB1	Scavenger receptor class B member 1; Belongs to the CD36 family. (467 aa)
	CYP2W1	Cytochrome P450 family 2 subfamily W member 1. (334 aa)
	HSD17B1	Estradiol 17-beta-dehydrogenase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (286 aa)
	CYP11A1	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] (521 aa)
	LOC103263091	Adenylate cyclase type 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (293 aa)
	ADCY6	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1166 aa)
	INSR	Tyrosine-protein kinase receptor. (1356 aa)
	JMJD7	jmjC domain-containing protein 7. (308 aa)
	LHB	Lutropin subunit beta. (141 aa)
	ADCY7	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1071 aa)
	CYP1A1	Cytochrome P450 1A1 isoform X1; Belongs to the cytochrome P450 family. (516 aa)
	LOC103253123	Adenylate cyclase type 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (327 aa)
	LDLR	Low-density lipoprotein receptor. (668 aa)
	ENSTSYP00000028505	annotation not available (242 aa)
	PLA2G4A	Phospholipase A2. (749 aa)
	IGF1	Insulin-like growth factor I isoform X1. (209 aa)
	HSD3B2	3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2; Belongs to the 3-beta-HSD family. (373 aa)
	ADCY5	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (915 aa)
	ENSTSYP00000032829	annotation not available (586 aa)
	LOC103273240	Acyl-coenzyme A thioesterase 1. (424 aa)

Your Current Organism:

Carlito syrichta

NCBI taxonomy Id: 1868482
Other names: C. syrichta, Philippine tarsier, Tarsius syrichta

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADCY2	ADCY4	ENSTSYP00000000205	ENSTSYP00000013056	Adenylate cyclase type 2.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.777
ADCY2	ADCY5	ENSTSYP00000000205	ENSTSYP00000030600	Adenylate cyclase type 2.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.956
ADCY2	ADCY6	ENSTSYP00000000205	ENSTSYP00000022780	Adenylate cyclase type 2.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.971
ADCY2	ADCY7	ENSTSYP00000000205	ENSTSYP00000025022	Adenylate cyclase type 2.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.615
ADCY2	ADCY8	ENSTSYP00000000205	ENSTSYP00000010804	Adenylate cyclase type 2.	Adenylate cyclase type 8; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.789
ADCY2	ADCY9	ENSTSYP00000000205	ENSTSYP00000008566	Adenylate cyclase type 2.	Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.863
ADCY2	ENSTSYP00000028505	ENSTSYP00000000205	ENSTSYP00000028505	Adenylate cyclase type 2.	annotation not available	0.864
ADCY2	ENSTSYP00000032829	ENSTSYP00000000205	ENSTSYP00000032829	Adenylate cyclase type 2.	annotation not available	0.974
ADCY2	LOC103253123	ENSTSYP00000000205	ENSTSYP00000026878	Adenylate cyclase type 2.	Adenylate cyclase type 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.562
ADCY2	LOC103255823	ENSTSYP00000000205	ENSTSYP00000000108	Adenylate cyclase type 2.	Guanine nucleotide-binding protein G(S) subunit alpha isoform X2.	0.977
ADCY2	LOC103263091	ENSTSYP00000000205	ENSTSYP00000022361	Adenylate cyclase type 2.	Adenylate cyclase type 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.570
ADCY2	PRKACA	ENSTSYP00000000205	ENSTSYP00000012740	Adenylate cyclase type 2.	cAMP-dependent protein kinase catalytic subunit alpha; Belongs to the protein kinase superfamily.	0.878
ADCY2	PRKACB	ENSTSYP00000000205	ENSTSYP00000000346	Adenylate cyclase type 2.	cAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily.	0.864
ADCY2	PTRHD1	ENSTSYP00000000205	ENSTSYP00000009125	Adenylate cyclase type 2.	Putative peptidyl-tRNA hydrolase PTRHD1.	0.562
ADCY3	ADCY5	ENSTSYP00000009203	ENSTSYP00000030600	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.704
ADCY3	ADCY6	ENSTSYP00000009203	ENSTSYP00000022780	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.836
ADCY3	ADCY8	ENSTSYP00000009203	ENSTSYP00000010804	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 8; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.843
ADCY3	ADCY9	ENSTSYP00000009203	ENSTSYP00000008566	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.888
ADCY3	ENSTSYP00000028505	ENSTSYP00000009203	ENSTSYP00000028505	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	annotation not available	0.864
ADCY3	ENSTSYP00000032829	ENSTSYP00000009203	ENSTSYP00000032829	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	annotation not available	0.927