STRINGSTRING
CREB3L4 CREB3L4 PPP3CC PPP3CC PDE3B PDE3B ATF2 ATF2 PPP3R1 PPP3R1 EP300 EP300 PRKACB PRKACB ADCY2 ADCY2 LOC103255823 LOC103255823 ITPR2 ITPR2 ENSTSYP00000013381 ENSTSYP00000013381 CAMK2A CAMK2A PRKACA PRKACA LDHB LDHB ACACB ACACB SIRT1 SIRT1 PRKAA2 PRKAA2 PFKP PFKP PRKAB1 PRKAB1 PHKB PHKB PYGM PYGM PVALEF PVALEF LOC103249516 LOC103249516 LOC103255950 LOC103255950 PPP3CA PPP3CA CPT1C CPT1C PFKL PFKL PRKAA1 PRKAA1 CALML4 CALML4 PLCB3 PLCB3 PRMT1 PRMT1 PDHB PDHB ENSTSYP00000019824 ENSTSYP00000019824 PPP4R3C PPP4R3C TNIK TNIK LOC103250483-2 LOC103250483-2 ENSTSYP00000019076 ENSTSYP00000019076 PHKA2 PHKA2 ENSTSYP00000018400 ENSTSYP00000018400 PPARGC1A PPARGC1A GCGR GCGR SIK1 SIK1 CAMK2D CAMK2D PFKFB1 PFKFB1 GYS2 GYS2 CPT1B CPT1B AKT2 AKT2 PKM PKM SIK2 SIK2 FBP1 FBP1 CAMK2G CAMK2G PHKG2 PHKG2 PPP4R3B PPP4R3B CREB3 CREB3 LDHA LDHA PLCB4 PLCB4 G6PC2 G6PC2 PCK2 PCK2 CREB3L1 CREB3L1 LDHAL6A LDHAL6A PHKG1 PHKG1 PLCB1 PLCB1 AKT3 AKT3 PCK1 PCK1 SLC2A1 SLC2A1 PRKAG3 PRKAG3 LOC103274254 LOC103274254 CREB3L2 CREB3L2 GYS1 GYS1 LOC103261438 LOC103261438 PLCB2 PLCB2 LOC103265127 LOC103265127 PPP4R3A PPP4R3A ITPR3 ITPR3 ENSTSYP00000027576 ENSTSYP00000027576 ARSI ARSI CAMK2B CAMK2B ENSTSYP00000028112 ENSTSYP00000028112 LOC103262926 LOC103262926 PRKAB2 PRKAB2 ENSTSYP00000028505 ENSTSYP00000028505 CALML6 CALML6 PGAM1 PGAM1 LOC103249210 LOC103249210 PARP8 PARP8 ENSTSYP00000030893 ENSTSYP00000030893 AKT1 AKT1 ENSTSYP00000031069 ENSTSYP00000031069 CALM3 CALM3 CREB3L3 CREB3L3 FBP2 FBP2 PPARA PPARA CRTC2 CRTC2 PYGB PYGB ACACA ACACA LOC103274775 LOC103274775 PPP3CB PPP3CB ENSTSYP00000032829 ENSTSYP00000032829 CREBBP CREBBP ATF4 ATF4 LOC103257967 LOC103257967 LOC103268605 LOC103268605 ENSTSYP00000033656 ENSTSYP00000033656 PRKAG1 PRKAG1 ENSTSYP00000034769 ENSTSYP00000034769 GCK GCK CREB1 CREB1 PGAM2 PGAM2 G6PC G6PC PDHA1 PDHA1 FAP FAP GCG GCG PFKM PFKM CREB5 CREB5 G6PC3 G6PC3 PARP6 PARP6 SLC2A2 SLC2A2 LOC103250483 LOC103250483 PPP4C PPP4C PYGL PYGL
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CREB3L4Cyclic AMP-responsive element-binding protein 3-like protein 4. (393 aa)
PPP3CCSerine/threonine-protein phosphatase. (514 aa)
PDE3BPhosphodiesterase. (797 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2 isoform X1. (507 aa)
PPP3R1Calcineurin subunit B type 1. (169 aa)
EP300Histone acetyltransferase p300. (2174 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily. (398 aa)
ADCY2Adenylate cyclase type 2. (955 aa)
LOC103255823Guanine nucleotide-binding protein G(S) subunit alpha isoform X2. (361 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2701 aa)
ENSTSYP00000013381annotation not available (299 aa)
CAMK2ACalcium/calmodulin-dependent protein kinase type II subunit alpha isoform X1; Belongs to the protein kinase superfamily. (489 aa)
PRKACAcAMP-dependent protein kinase catalytic subunit alpha; Belongs to the protein kinase superfamily. (343 aa)
LDHBL-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (334 aa)
ACACBLOW QUALITY PROTEIN: acetyl-CoA carboxylase 2. (2433 aa)
SIRT1NAD-dependent protein deacetylase sirtuin-1 isoform X1. (729 aa)
PRKAA2Non-specific serine/threonine protein kinase. (529 aa)
PFKPATP-dependent 6-phosphofructokinase, platelet type. (742 aa)
PRKAB15'-AMP-activated protein kinase subunit beta-1 isoform X1. (270 aa)
PHKBPhosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. Belongs to the phosphorylase b kinase regulatory chain family. (1132 aa)
PYGMAlpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (820 aa)
PVALEFParvalbumin like EF-hand containing. (134 aa)
LOC103249516Inositol 1,4,5-trisphosphate receptor type 1. (389 aa)
LOC103255950Calmodulin-like; Belongs to the calmodulin family. (131 aa)
PPP3CASerine/threonine-protein phosphatase. (521 aa)
CPT1CCarnitine O-palmitoyltransferase 1, brain isoform; Belongs to the carnitine/choline acetyltransferase family. (665 aa)
PFKLATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (774 aa)
PRKAA1Non-specific serine/threonine protein kinase. (574 aa)
CALML4LOW QUALITY PROTEIN: calmodulin-like protein 4. (192 aa)
PLCB3Phosphoinositide phospholipase C. (828 aa)
PRMT1Protein arginine N-methyltransferase 1 isoform X1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (371 aa)
PDHBPyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (359 aa)
ENSTSYP00000019824annotation not available (90 aa)
PPP4R3CSerine/threonine-protein phosphatase 4 regulatory subunit 3B-like. (816 aa)
TNIKTRAF2 and NCK-interacting protein kinase. (1293 aa)
LOC103250483-2Calmodulin-2/4-like isoform X2; Belongs to the calmodulin family. (141 aa)
ENSTSYP00000019076annotation not available (195 aa)
PHKA2Phosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. (1235 aa)
ENSTSYP00000018400annotation not available (338 aa)
PPARGC1APeroxisome proliferator-activated receptor gamma coactivator 1-alpha isoform X2. (798 aa)
GCGRGlucagon receptor; Belongs to the G-protein coupled receptor 2 family. (499 aa)
SIK1Serine/threonine-protein kinase SIK1. (779 aa)
CAMK2DCalcium/calmodulin-dependent protein kinase type II subunit delta isoform X4. (533 aa)
PFKFB16-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase 1 isoform X1. (470 aa)
GYS2Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan. (703 aa)
CPT1BCarnitine O-palmitoyltransferase 1, muscle isoform isoform X1; Belongs to the carnitine/choline acetyltransferase family. (772 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
PKMPyruvate kinase; Belongs to the pyruvate kinase family. (537 aa)
SIK2Serine/threonine-protein kinase SIK2. (793 aa)
FBP1Fructose-1,6-bisphosphatase 1; Belongs to the FBPase class 1 family. (369 aa)
CAMK2GCalcium/calmodulin-dependent protein kinase type II subunit gamma. (566 aa)
PHKG2Phosphorylase b kinase gamma catalytic chain, liver/testis isoform; Belongs to the protein kinase superfamily. (406 aa)
PPP4R3BSerine/threonine-protein phosphatase 4 regulatory subunit 3B isoform X1. (841 aa)
CREB3Cyclic AMP-responsive element-binding protein 3 isoform X2. (371 aa)
LDHAL-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (361 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1194 aa)
G6PC2Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (355 aa)
PCK2Phosphoenolpyruvate carboxykinase [GTP], mitochondrial isoform X1. (640 aa)
CREB3L1Cyclic AMP-responsive element-binding protein 3-like protein 1. (520 aa)
LDHAL6AL-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (281 aa)
PHKG1Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform; Belongs to the protein kinase superfamily. (396 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1135 aa)
AKT3RAC-gamma serine/threonine-protein kinase; Belongs to the protein kinase superfamily. (419 aa)
PCK1Phosphoenolpyruvate carboxykinase, cytosolic [GTP]. (622 aa)
SLC2A1Solute carrier family 2, facilitated glucose transporter member 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (460 aa)
PRKAG35'-AMP-activated protein kinase subunit gamma-3. (489 aa)
LOC103274254Fructose-1,6-bisphosphatase 1-like; Belongs to the FBPase class 1 family. (316 aa)
CREB3L2Cyclic AMP-responsive element-binding protein 3-like protein 2. (520 aa)
GYS1Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan. (737 aa)
LOC103261438Calmodulin-like; Belongs to the calmodulin family. (130 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1094 aa)
LOC103265127L-lactate dehydrogenase C chain-like. (139 aa)
PPP4R3ASerine/threonine-protein phosphatase 4 regulatory subunit 3A. (1102 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2677 aa)
ENSTSYP00000027576annotation not available (278 aa)
ARSIArylsulfatase I. (535 aa)
CAMK2BCalcium/calmodulin-dependent protein kinase type II subunit beta. (666 aa)
ENSTSYP00000028112annotation not available (112 aa)
LOC103262926LOW QUALITY PROTEIN: phosphoglycerate mutase 1-like. (240 aa)
PRKAB25'-AMP-activated protein kinase subunit beta-2 isoform X1. (272 aa)
ENSTSYP00000028505annotation not available (242 aa)
CALML6Calmodulin-like protein 6. (164 aa)
PGAM1Phosphoglycerate mutase 1. (210 aa)
LOC103249210Carnitine O-palmitoyltransferase 1, liver isoform-like. (45 aa)
PARP8Poly [ADP-ribose] polymerase. (854 aa)
ENSTSYP00000030893annotation not available (343 aa)
AKT1Non-specific serine/threonine protein kinase. (393 aa)
ENSTSYP00000031069annotation not available (149 aa)
CALM3Calmodulin 3. (128 aa)
CREB3L3LOW QUALITY PROTEIN: cyclic AMP-responsive element-binding protein 3-like protein 3. (330 aa)
FBP2Fructose-1,6-bisphosphatase isozyme 2; Belongs to the FBPase class 1 family. (339 aa)
PPARAPeroxisome proliferator-activated receptor alpha. (473 aa)
CRTC2CREB-regulated transcription coactivator 2. (689 aa)
PYGBAlpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (842 aa)
ACACAacetyl-CoA carboxylase 1. (2383 aa)
LOC103274775L-lactate dehydrogenase A chain-like; Belongs to the LDH/MDH superfamily. (349 aa)
PPP3CBSerine/threonine-protein phosphatase. (525 aa)
ENSTSYP00000032829annotation not available (586 aa)
CREBBPCREB-binding protein isoform X1. (2433 aa)
ATF4Cyclic AMP-dependent transcription factor ATF-4 isoform X2. (352 aa)
LOC103257967Calmodulin-like; Belongs to the calmodulin family. (147 aa)
LOC103268605Calmodulin isoform X1; Belongs to the calmodulin family. (149 aa)
ENSTSYP00000033656annotation not available (345 aa)
PRKAG15'-AMP-activated protein kinase subunit gamma-1 isoform X1. (343 aa)
ENSTSYP00000034769annotation not available (133 aa)
GCKPhosphotransferase. (467 aa)
CREB1Cyclic AMP-responsive element-binding protein 1 isoform X1. (341 aa)
PGAM2Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (253 aa)
G6PCGlucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (357 aa)
PDHA1Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (422 aa)
FAPProlyl endopeptidase FAP isoform X1; Belongs to the peptidase S9B family. (760 aa)
GCGGlucagon. (180 aa)
PFKMATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (851 aa)
CREB5Cyclic AMP-responsive element-binding protein 5 isoform X1. (508 aa)
G6PC3Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (346 aa)
PARP6Poly [ADP-ribose] polymerase. (631 aa)
SLC2A2Solute carrier family 2, facilitated glucose transporter member 2 isoform X1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (522 aa)
LOC103250483calmodulin-A-like isoform X1; Belongs to the calmodulin family. (150 aa)
PPP4CSerine/threonine-protein phosphatase. (307 aa)
PYGLAlpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (851 aa)
Your Current Organism:
Carlito syrichta
NCBI taxonomy Id: 1868482
Other names: C. syrichta, Philippine tarsier, Tarsius syrichta
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