STRINGSTRING
RPS6KA6 RPS6KA6 PPARGC1B PPARGC1B PRKAG1 PRKAG1 PIK3CB PIK3CB SLC27A3 SLC27A3 LOC103277171 LOC103277171 MLXIPL MLXIPL PYGB PYGB CRTC2 CRTC2 ENSTSYP00000031894 ENSTSYP00000031894 PPARA PPARA PRKCQ PRKCQ RPS6KA2 RPS6KA2 IL6 IL6 PTEN PTEN RPS6KB2 RPS6KB2 CREB3L3 CREB3L3 RPS6KA1 RPS6KA1 MAPK9 MAPK9 AKT1 AKT1 LOC103249210 LOC103249210 MLX MLX LOC103252205 LOC103252205 PIK3CD PIK3CD PRKAB2 PRKAB2 PPP1CA PPP1CA SREBF1 SREBF1 TNFRSF1A TNFRSF1A TNF TNF MAPK8 MAPK8 PPP1R3A PPP1R3A GYS1 GYS1 NOS3 NOS3 PRKAB1 PRKAB1 PYGM PYGM PIK3R3 PIK3R3 PTPA PTPA RELA RELA TRIB3 TRIB3 ENSTSYP00000023642 ENSTSYP00000023642 INSR INSR ENSTSYP00000022866 ENSTSYP00000022866 PPP1R3C PPP1R3C PRKCZ PRKCZ SLC27A5 SLC27A5 NR1H2 NR1H2 PIK3R1 PIK3R1 PRKAA1 PRKAA1 PPP1R3B PPP1R3B TNIK TNIK SLC2A4 SLC2A4 RPS6KB1 RPS6KB1 PTPRF PTPRF OGA OGA PPARGC1A PPARGC1A NR1H3 NR1H3 CD36 CD36 SOCS3 SOCS3 GSK3B GSK3B GYS2 GYS2 CPT1B CPT1B AKT2 AKT2 NFU1 NFU1 ACACB ACACB MTOR MTOR RPS6KA3 RPS6KA3 STAT3 STAT3 PRKAA2 PRKAA2 CREB3L2 CREB3L2 PRKAG3 PRKAG3 SLC2A1 SLC2A1 PCK1 PCK1 AKT3 AKT3 OGT OGT LOC103251683 LOC103251683 PPP1CB PPP1CB CREB3L1 CREB3L1 PCK2 PCK2 G6PC2 G6PC2 MLXIP MLXIP CREB3 CREB3 PRKCD PRKCD SLC27A6 SLC27A6 CREB1 CREB1 PDPK1 PDPK1 G6PC G6PC TBC1D4 TBC1D4 MAPK10 MAPK10 CREB5 CREB5 AGT AGT G6PC3 G6PC3 NFKB1 NFKB1 PPP1R3E PPP1R3E GFPT1 GFPT1 SLC2A2 SLC2A2 PYGL PYGL PIK3CA PIK3CA CREB3L4 CREB3L4 NFKBIA NFKBIA IKBKB IKBKB SLC27A4 SLC27A4 PTPN11 PTPN11 SLC27A2 SLC27A2 PTPN1 PTPN1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RPS6KA6Non-specific serine/threonine protein kinase. (718 aa)
PPARGC1BPeroxisome proliferator-activated receptor gamma coactivator 1-beta. (978 aa)
PRKAG15'-AMP-activated protein kinase subunit gamma-1 isoform X1. (343 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X2; Belongs to the PI3/PI4-kinase family. (1070 aa)
SLC27A3Long-chain fatty acid transport protein 3. (811 aa)
LOC103277171LOW QUALITY PROTEIN: signal transducer and activator of transcription 3-like. (248 aa)
MLXIPLCarbohydrate-responsive element-binding protein. (601 aa)
PYGBAlpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (842 aa)
CRTC2CREB-regulated transcription coactivator 2. (689 aa)
ENSTSYP00000031894annotation not available (263 aa)
PPARAPeroxisome proliferator-activated receptor alpha. (473 aa)
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (706 aa)
RPS6KA2Non-specific serine/threonine protein kinase. (729 aa)
IL6Interleukin-6. (209 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
RPS6KB2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (482 aa)
CREB3L3LOW QUALITY PROTEIN: cyclic AMP-responsive element-binding protein 3-like protein 3. (330 aa)
RPS6KA1Ribosomal protein S6 kinase. (744 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
AKT1Non-specific serine/threonine protein kinase. (393 aa)
LOC103249210Carnitine O-palmitoyltransferase 1, liver isoform-like. (45 aa)
MLXMax-like protein X isoform X2. (295 aa)
LOC103252205Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (337 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1063 aa)
PRKAB25'-AMP-activated protein kinase subunit beta-2 isoform X1. (272 aa)
PPP1CASerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (322 aa)
SREBF1Sterol regulatory element-binding protein 1. (1177 aa)
TNFRSF1ATumor necrosis factor receptor superfamily member 1A. (183 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (232 aa)
MAPK8Mitogen-activated protein kinase. (384 aa)
PPP1R3AProtein phosphatase 1 regulatory subunit 3A. (1121 aa)
GYS1Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan. (737 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1209 aa)
PRKAB15'-AMP-activated protein kinase subunit beta-1 isoform X1. (270 aa)
PYGMAlpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (820 aa)
PIK3R3Phosphatidylinositol 3-kinase regulatory subunit gamma isoform X2. (461 aa)
PTPASerine/threonine-protein phosphatase 2A activator; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. (338 aa)
RELATranscription factor p65. (519 aa)
TRIB3Tribbles homolog 3. (358 aa)
ENSTSYP00000023642annotation not available (224 aa)
INSRTyrosine-protein kinase receptor. (1356 aa)
ENSTSYP00000022866annotation not available (318 aa)
PPP1R3CProtein phosphatase 1 regulatory subunit. (316 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (558 aa)
SLC27A5Bile acyl-CoA synthetase. (622 aa)
NR1H2Oxysterols receptor LXR-beta. (449 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (612 aa)
PRKAA1Non-specific serine/threonine protein kinase. (574 aa)
PPP1R3BProtein phosphatase 1 regulatory subunit. (286 aa)
TNIKTRAF2 and NCK-interacting protein kinase. (1293 aa)
SLC2A4Solute carrier family 2, facilitated glucose transporter member 4 isoform X1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (509 aa)
RPS6KB1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa)
PTPRFReceptor-type tyrosine-protein phosphatase F. (1908 aa)
OGAProtein O-GlcNAcase isoform X1. (849 aa)
PPARGC1APeroxisome proliferator-activated receptor gamma coactivator 1-alpha isoform X2. (798 aa)
NR1H3Oxysterols receptor LXR-alpha isoform X1. (447 aa)
CD36Platelet glycoprotein 4; Belongs to the CD36 family. (472 aa)
SOCS3Suppressor of cytokine signaling 3. (225 aa)
GSK3BGlycogen synthase kinase-3 beta; Belongs to the protein kinase superfamily. (403 aa)
GYS2Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan. (703 aa)
CPT1BCarnitine O-palmitoyltransferase 1, muscle isoform isoform X1; Belongs to the carnitine/choline acetyltransferase family. (772 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
NFU1NFU1 iron-sulfur cluster scaffold homolog, mitochondrial isoform X1. (256 aa)
ACACBLOW QUALITY PROTEIN: acetyl-CoA carboxylase 2. (2433 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2548 aa)
RPS6KA3Non-specific serine/threonine protein kinase. (729 aa)
STAT3Signal transducer and activator of transcription 3. (444 aa)
PRKAA2Non-specific serine/threonine protein kinase. (529 aa)
CREB3L2Cyclic AMP-responsive element-binding protein 3-like protein 2. (520 aa)
PRKAG35'-AMP-activated protein kinase subunit gamma-3. (489 aa)
SLC2A1Solute carrier family 2, facilitated glucose transporter member 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (460 aa)
PCK1Phosphoenolpyruvate carboxykinase, cytosolic [GTP]. (622 aa)
AKT3RAC-gamma serine/threonine-protein kinase; Belongs to the protein kinase superfamily. (419 aa)
OGTUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit isoform X1. (1046 aa)
LOC103251683Insulin-like; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (99 aa)
PPP1CBSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (313 aa)
CREB3L1Cyclic AMP-responsive element-binding protein 3-like protein 1. (520 aa)
PCK2Phosphoenolpyruvate carboxykinase [GTP], mitochondrial isoform X1. (640 aa)
G6PC2Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (355 aa)
MLXIPMLX-interacting protein. (925 aa)
CREB3Cyclic AMP-responsive element-binding protein 3 isoform X2. (371 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (674 aa)
SLC27A6Long-chain fatty acid transport protein 6. (619 aa)
CREB1Cyclic AMP-responsive element-binding protein 1 isoform X1. (341 aa)
PDPK13-phosphoinositide-dependent protein kinase 1. (554 aa)
G6PCGlucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (357 aa)
TBC1D4TBC1 domain family member 4 isoform X1. (1297 aa)
MAPK10Mitogen-activated protein kinase. (473 aa)
CREB5Cyclic AMP-responsive element-binding protein 5 isoform X1. (508 aa)
AGTAngiotensinogen; Belongs to the serpin family. (487 aa)
G6PC3Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (346 aa)
NFKB1Nuclear factor NF-kappa-B p105 subunit isoform X1. (964 aa)
PPP1R3ELOW QUALITY PROTEIN: protein phosphatase 1 regulatory subunit 3E. (231 aa)
GFPT1Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 isoform X1. (699 aa)
SLC2A2Solute carrier family 2, facilitated glucose transporter member 2 isoform X1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (522 aa)
PYGLAlpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (851 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
CREB3L4Cyclic AMP-responsive element-binding protein 3-like protein 4. (393 aa)
NFKBIANF-kappa-B inhibitor alpha. (282 aa)
IKBKBInhibitor of nuclear factor kappa-B kinase subunit beta isoform X1. (756 aa)
SLC27A4Long-chain fatty acid transport protein 4 isoform X1. (643 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type 11. (532 aa)
SLC27A2LOW QUALITY PROTEIN: very long-chain acyl-CoA synthetase-like. (418 aa)
PTPN1Tyrosine-protein phosphatase non-receptor type. (434 aa)
Your Current Organism:
Carlito syrichta
NCBI taxonomy Id: 1868482
Other names: C. syrichta, Philippine tarsier, Tarsius syrichta
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