(108 nodes) Protein digestion and absorption network (Carlito syrichta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	COL11A2	Collagen alpha-2(XI) chain isoform X1. (1736 aa)
	SLC1A5	Amino acid transporter. (449 aa)
	LOC103270996	Chymosin; Belongs to the peptidase A1 family. (381 aa)
	SLC36A2	Proton-coupled amino acid transporter 2. (483 aa)
	SLC8A1	Sodium/calcium exchanger 1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (973 aa)
	LOC103249430	Pepsin A; Belongs to the peptidase A1 family. (387 aa)
	FXYD2	FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (66 aa)
	SLC7A8	Large neutral amino acids transporter small subunit 2 isoform X1. (535 aa)
	COL16A1	Collagen alpha-1(XVI) chain. (1610 aa)
	ATP1A3	Sodium/potassium-transporting ATPase subunit alpha. (1036 aa)
	ATP1A1	Sodium/potassium-transporting ATPase subunit alpha. (1025 aa)
	SLC7A9	B(0,+)-type amino acid transporter 1. (389 aa)
	CELA1	Chymotrypsin-like elastase family member 1; Belongs to the peptidase S1 family. (256 aa)
	SLC9A3	Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (746 aa)
	SLC7A6	Y+L amino acid transporter 2. (511 aa)
	CELA3B	Chymotrypsin-like elastase family member 3B; Belongs to the peptidase S1 family. (269 aa)
	SLC38A2	Sodium-coupled neutral amino acid transporter 2 isoform X1. (505 aa)
	SLC7A10	Asc-type amino acid transporter 1. (480 aa)
	COL10A1	Collagen alpha-1(X) chain. (673 aa)
	LOC103261014	Cationic trypsin-3; Belongs to the peptidase S1 family. (248 aa)
	KCNN4	Intermediate conductance calcium-activated potassium channel protein 4. (260 aa)
	LOC103270188	Chymotrypsinogen B; Belongs to the peptidase S1 family. (263 aa)
	COL6A6	LOW QUALITY PROTEIN: collagen alpha-6(VI) chain. (1911 aa)
	COL23A1	Collagen alpha-1(XXIII) chain-like. (396 aa)
	ATP1B4	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (352 aa)
	MFF-2	Mitochondrial fission factor isoform X2. (342 aa)
	LOC103251607	Chymotrypsinogen B2-like; Belongs to the peptidase S1 family. (215 aa)
	COL5A1	Collagen alpha-1(V) chain. (1844 aa)
	PRSS2	Trypsin-2; Belongs to the peptidase S1 family. (247 aa)
	KCNQ1	Potassium voltage-gated channel subfamily KQT member 1; Belongs to the potassium channel family. (422 aa)
	C1QTNF2	Complement C1q tumor necrosis factor-related protein 2. (327 aa)
	COL27A1	Collagen alpha-1(XXVII) chain. (1840 aa)
	SLC3A2	4F2 cell-surface antigen heavy chain. (629 aa)
	ATP1B2	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (290 aa)
	CTRC	chymotrypsin-C; Belongs to the peptidase S1 family. (268 aa)
	COL20A1	Collagen alpha-1(XX) chain. (1286 aa)
	SLC36A1	Proton-coupled amino acid transporter 1. (476 aa)
	COL1A1	Collagen alpha-1(I) chain. (1462 aa)
	COL9A3	Collagen alpha-3(IX) chain. (612 aa)
	LOC103262178	Collagen alpha-5(IV) chain-like. (461 aa)
	C1QTNF7	Complement C1q tumor necrosis factor-related protein 7 isoform X1. (308 aa)
	COL6A2	Collagen alpha-2(VI) chain isoform X1. (1019 aa)
	COL8A2	Collagen alpha-2(VIII) chain isoform X1. (700 aa)
	LOC103254377	Collagen alpha-1(XXI) chain. (508 aa)
	COL5A3	LOW QUALITY PROTEIN: collagen alpha-3(V) chain. (1676 aa)
	CPA1	Carboxypeptidase A1. (419 aa)
	KCNK5	Potassium channel subfamily K member 5; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (497 aa)
	LOC103253083	Sodium/calcium exchanger 3-like; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (298 aa)
	ATP1A2	Sodium/potassium-transporting ATPase subunit alpha. (1035 aa)
	SLC6A19	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (627 aa)
	COL17A1	Collagen alpha-1(XVII) chain. (420 aa)
	COL18A1	Collagen alpha-1(XVIII) chain isoform X2. (1512 aa)
	COL5A2	Collagen alpha-2(V) chain isoform X1. (1499 aa)
	SLC7A7	Y+L amino acid transporter 1. (511 aa)
	CPB2	Carboxypeptidase B2. (261 aa)
	COL6A1	Collagen alpha-1(VI) chain. (1028 aa)
	COL9A2	Collagen alpha-2(IX) chain. (636 aa)
	SLC9A5	Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (886 aa)
	SLC15A1	Solute carrier family 15 member 1. (706 aa)
	COL4A1	Collagen alpha-1(IV) chain. (1621 aa)
	COL3A1	Collagen alpha-1(III) chain. (1466 aa)
	COL25A1	Collagen alpha-1(XXV) chain. (493 aa)
	SLC36A4	Proton-coupled amino acid transporter 4 isoform X1. (491 aa)
	ACE2	Angiotensin-converting enzyme. (805 aa)
	ATP1B1	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (303 aa)
	MME	Neprilysin. (750 aa)
	COL4A5	Collagen alpha-5(IV) chain. (622 aa)
	COL4A6	Collagen alpha-6(IV) chain isoform X1. (1706 aa)
	MEP1A	Meprin A subunit. (749 aa)
	COL12A1	Collagen alpha-1(XII) chain. (3007 aa)
	XPNPEP2	xaa-Pro aminopeptidase 2; Belongs to the peptidase M24B family. (674 aa)
	CPA3	Mast cell carboxypeptidase A. (417 aa)
	CPB1	Carboxypeptidase B. (412 aa)
	EMID1	EMI domain-containing protein 1. (445 aa)
	COL28A1	Collagen alpha-1(XXVIII) chain. (1126 aa)
	SLC1A1	Amino acid transporter. (524 aa)
	COL1A2	Collagen alpha-2(I) chain isoform X2. (1366 aa)
	COL24A1	Collagen alpha-1(XXIV) chain-like. (944 aa)
	MEP1B	Meprin A subunit. (701 aa)
	OVCH2	Ovochymase-2; Belongs to the peptidase S1 family. (611 aa)
	CPA4	Carboxypeptidase A4 isoform X1. (420 aa)
	COL13A1	Collagen alpha-1(XIII) chain. (713 aa)
	LOC103260475	Chymotrypsin-like elastase family member 2A; Belongs to the peptidase S1 family. (268 aa)
	CPA6	Carboxypeptidase A6. (383 aa)
	CPA2	Carboxypeptidase A2 isoform X1. (419 aa)
	COL22A1	Collagen alpha-1(XXII) chain. (1091 aa)
	SLC36A3	Proton-coupled amino acid transporter 3. (511 aa)
	COL15A1	Collagen alpha-1(XV) chain. (1328 aa)
	SLC3A1	Neutral and basic amino acid transport protein rBAT isoform X2. (685 aa)
	COL7A1	Collagen alpha-1(VII) chain. (2943 aa)
	COL14A1	Collagen alpha-1(XIV) chain. (1692 aa)
	ATP1A4	Sodium/potassium-transporting ATPase subunit alpha. (1029 aa)
	LOC103259286	Collagen alpha-3(IV) chain-like. (884 aa)
	COL8A1	Collagen alpha-1(VIII) chain. (745 aa)
	VWA2	Von Willebrand factor A domain-containing protein 2. (756 aa)
	KCNJ13	Inward rectifier potassium channel 13 isoform X1. (360 aa)
	COL4A4	Collagen alpha-4(IV) chain. (1691 aa)
	PRCP	Lysosomal Pro-X carboxypeptidase. (440 aa)
	COL6A3	Collagen alpha-3(VI) chain. (3159 aa)
	DPP4	Dipeptidyl peptidase 4; Belongs to the peptidase S9B family. (733 aa)
	CTRL	Chymotrypsin-like protease CTRL-1; Belongs to the peptidase S1 family. (264 aa)
	COL2A1	Collagen alpha-1(II) chain. (1487 aa)
	COL11A1	Collagen alpha-1(XI) chain. (1446 aa)
	PRSS37	Probable inactive serine protease 37 isoform X1. (235 aa)
	COL9A1	Collagen alpha-1(IX) chain. (914 aa)
	COL19A1	Collagen alpha-1(XIX) chain. (1138 aa)
	TMEM27	Collectrin. (222 aa)
	COL4A2	Collagen alpha-2(IV) chain. (1702 aa)

Your Current Organism:

Carlito syrichta

NCBI taxonomy Id: 1868482
Other names: C. syrichta, Philippine tarsier, Tarsius syrichta

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACE2	DPP4	ENSTSYP00000010149	ENSTSYP00000001818	Angiotensin-converting enzyme.	Dipeptidyl peptidase 4; Belongs to the peptidase S9B family.	0.924
ACE2	MEP1A	ENSTSYP00000010149	ENSTSYP00000008793	Angiotensin-converting enzyme.	Meprin A subunit.	0.871
ACE2	MEP1B	ENSTSYP00000010149	ENSTSYP00000007197	Angiotensin-converting enzyme.	Meprin A subunit.	0.861
ACE2	MME	ENSTSYP00000010149	ENSTSYP00000009194	Angiotensin-converting enzyme.	Neprilysin.	0.906
ACE2	PRCP	ENSTSYP00000010149	ENSTSYP00000002049	Angiotensin-converting enzyme.	Lysosomal Pro-X carboxypeptidase.	0.888
ACE2	SLC6A19	ENSTSYP00000010149	ENSTSYP00000014794	Angiotensin-converting enzyme.	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.	0.987
ACE2	XPNPEP2	ENSTSYP00000010149	ENSTSYP00000008076	Angiotensin-converting enzyme.	xaa-Pro aminopeptidase 2; Belongs to the peptidase M24B family.	0.862
ATP1A1	ATP1A3	ENSTSYP00000032630	ENSTSYP00000034024	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit alpha.	0.885
ATP1A1	ATP1A4	ENSTSYP00000032630	ENSTSYP00000003560	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit alpha.	0.818
ATP1A1	ATP1B1	ENSTSYP00000032630	ENSTSYP00000009368	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.987
ATP1A1	ATP1B2	ENSTSYP00000032630	ENSTSYP00000021618	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.952
ATP1A1	ATP1B4	ENSTSYP00000032630	ENSTSYP00000025198	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.938
ATP1A1	FXYD2	ENSTSYP00000032630	ENSTSYP00000034269	Sodium/potassium-transporting ATPase subunit alpha.	FXYD domain-containing ion transport regulator; Belongs to the FXYD family.	0.984
ATP1A1	LOC103253083	ENSTSYP00000032630	ENSTSYP00000016498	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/calcium exchanger 3-like; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.	0.400
ATP1A1	SLC3A2	ENSTSYP00000032630	ENSTSYP00000021697	Sodium/potassium-transporting ATPase subunit alpha.	4F2 cell-surface antigen heavy chain.	0.461
ATP1A1	SLC8A1	ENSTSYP00000032630	ENSTSYP00000034536	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/calcium exchanger 1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.	0.452
ATP1A2	ATP1A3	ENSTSYP00000015208	ENSTSYP00000034024	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit alpha.	0.885
ATP1A2	ATP1A4	ENSTSYP00000015208	ENSTSYP00000003560	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit alpha.	0.818
ATP1A2	ATP1B1	ENSTSYP00000015208	ENSTSYP00000009368	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.987
ATP1A2	ATP1B2	ENSTSYP00000015208	ENSTSYP00000021618	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.952