STRINGSTRING
TGFB3 TGFB3 LAMB3 LAMB3 ACTN1 ACTN1 RAB5C RAB5C TGFB1 TGFB1 SMTNL1 SMTNL1 TGFB2 TGFB2 IL6 IL6 ENSTSYP00000031669 ENSTSYP00000031669 GNA15 GNA15 ENSTSYP00000032829 ENSTSYP00000032829 PRKCG PRKCG ACTN4 ACTN4 ENSTSYP00000033562 ENSTSYP00000033562 ENSTSYP00000033575 ENSTSYP00000033575 SMTNL2 SMTNL2 SMTN SMTN PIK3CB PIK3CB PIK3CD PIK3CD SERPINB6 SERPINB6 NOS2 NOS2 ENSTSYP00000028505 ENSTSYP00000028505 TNF TNF LOC103253123 LOC103253123 PLCB2 PLCB2 GNAL GNAL PIK3R3 PIK3R3 PTK2 PTK2 MFF-2 MFF-2 RELA RELA SPECC1L SPECC1L LOC103263091 LOC103263091 LAMC1 LAMC1 SPECC1 SPECC1 GNA11 GNA11 PIK3R1 PIK3R1 TRANK1 TRANK1 LAMA3 LAMA3 PLCB3 PLCB3 LAMA5 LAMA5 RAB7B RAB7B LOC103255823 LOC103255823 VCL VCL COL4A2 COL4A2 PRKACB PRKACB LAMC3 LAMC3 GNA14 GNA14 CD14 CD14 IL12A IL12A LAMA2 LAMA2 SERPINB10 SERPINB10 LAMA1 LAMA1 CD1D CD1D IFNG IFNG RAB7A RAB7A COL4A4 COL4A4 CTSG CTSG LOC103259286 LOC103259286 TLR4 TLR4 SERPINB9 SERPINB9 CXCL8 CXCL8 PRKCA PRKCA PIK3CA PIK3CA C8B C8B NFKB1 NFKB1 IL10 IL10 RAB5A RAB5A ARG2 ARG2 IL1B IL1B LOC103269696 LOC103269696 COL1A2 COL1A2 FN1 FN1 PLCB4 PLCB4 LAMB2 LAMB2 CXCL1 CXCL1 CSF2 CSF2 IL1R2 IL1R2 LOC103257846 LOC103257846 GNAQ GNAQ C9 C9 PLCB1 PLCB1 LOC103274700 LOC103274700 IL1R1 IL1R1 LAMC2 LAMC2 COL4A6 COL4A6 COL4A5 COL4A5 ARG1 ARG1 LAMB1 LAMB1 PRDX1 PRDX1 ITGAM ITGAM PRKCB PRKCB SERPINB8 SERPINB8 RAB17 RAB17 COL3A1 COL3A1 LAMB4 LAMB4 COL4A1 COL4A1 PRKACA PRKACA LAMA4 LAMA4 CD1A CD1A IL12B IL12B C8A C8A ENSTSYP00000014000 ENSTSYP00000014000 ENSTSYP00000014082 ENSTSYP00000014082 ENSTSYP00000014268 ENSTSYP00000014268 PRDX2 PRDX2 RAB5B RAB5B ITGB2 ITGB2 COL1A1 COL1A1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
LAMB3Laminin subunit beta-3. (1170 aa)
ACTN1Alpha-actinin-1 isoform X1. (888 aa)
RAB5CRas-related protein Rab-5C isoform X2. (229 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (344 aa)
SMTNL1Smoothelin-like protein 1. (208 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
IL6Interleukin-6. (209 aa)
ENSTSYP00000031669annotation not available (208 aa)
GNA15Guanine nucleotide-binding protein subunit alpha-15. (250 aa)
ENSTSYP00000032829annotation not available (586 aa)
PRKCGProtein kinase C. (634 aa)
ACTN4Alpha-actinin-4 isoform X2. (880 aa)
ENSTSYP00000033562annotation not available (97 aa)
ENSTSYP00000033575annotation not available (122 aa)
SMTNL2Smoothelin-like protein 2. (315 aa)
SMTNSmoothelin. (906 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X2; Belongs to the PI3/PI4-kinase family. (1070 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1063 aa)
SERPINB6Serpin B6; Belongs to the serpin family. (386 aa)
NOS2Nitric oxide synthase; Produces nitric oxide (NO). (1153 aa)
ENSTSYP00000028505annotation not available (242 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (232 aa)
LOC103253123Adenylate cyclase type 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (327 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1094 aa)
GNALGuanine nucleotide-binding protein G(Olf) subunit alpha. (380 aa)
PIK3R3Phosphatidylinositol 3-kinase regulatory subunit gamma isoform X2. (461 aa)
PTK2Focal adhesion kinase 1 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1096 aa)
MFF-2Mitochondrial fission factor isoform X2. (342 aa)
RELATranscription factor p65. (519 aa)
SPECC1Lcytospin-A isoform X1. (1118 aa)
LOC103263091Adenylate cyclase type 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (293 aa)
LAMC1Laminin subunit gamma-1. (1593 aa)
SPECC1cytospin-B isoform X1. (1068 aa)
GNA11Guanine nucleotide-binding protein subunit alpha-11. (235 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (612 aa)
TRANK1TPR and ankyrin repeat-containing protein 1. (2947 aa)
LAMA3Laminin subunit alpha-3. (892 aa)
PLCB3Phosphoinositide phospholipase C. (828 aa)
LAMA5Laminin subunit alpha-5. (3488 aa)
RAB7BRas-related protein Rab-7b. (199 aa)
LOC103255823Guanine nucleotide-binding protein G(S) subunit alpha isoform X2. (361 aa)
VCLVinculin. (1122 aa)
COL4A2Collagen alpha-2(IV) chain. (1702 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily. (398 aa)
LAMC3Laminin subunit gamma-3. (1431 aa)
GNA14Guanine nucleotide-binding protein subunit alpha-14. (355 aa)
CD14Monocyte differentiation antigen CD14. (376 aa)
IL12AInterleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (233 aa)
LAMA2Laminin subunit alpha-2. (2586 aa)
SERPINB10Serpin B10; Belongs to the serpin family. (397 aa)
LAMA1Laminin subunit alpha-1. (3075 aa)
CD1DAntigen-presenting glycoprotein CD1d-like. (297 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (165 aa)
RAB7ARas-related protein Rab-7a isoform X1. (214 aa)
COL4A4Collagen alpha-4(IV) chain. (1691 aa)
CTSGCathepsin G-like; Belongs to the peptidase S1 family. (256 aa)
LOC103259286Collagen alpha-3(IV) chain-like. (884 aa)
TLR4Toll-like receptor 4 isoform X1; Belongs to the Toll-like receptor family. (840 aa)
SERPINB9Serpin B9; Belongs to the serpin family. (375 aa)
CXCL8Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (95 aa)
PRKCAProtein kinase C. (614 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
C8BComplement component C8 beta chain isoform X1. (595 aa)
NFKB1Nuclear factor NF-kappa-B p105 subunit isoform X1. (964 aa)
IL10Interleukin-10. (178 aa)
RAB5ARas-related protein Rab-5A isoform X1. (215 aa)
ARG2Arginase. (354 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (267 aa)
LOC103269696Serpin B4-like isoform X1; Belongs to the serpin family. (389 aa)
COL1A2Collagen alpha-2(I) chain isoform X2. (1366 aa)
FN1Fibronectin isoform X2. (2450 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1194 aa)
LAMB2Laminin subunit beta-2. (1798 aa)
CXCL1C-X-C motif chemokine. (107 aa)
CSF2Granulocyte-macrophage colony-stimulating factor. (144 aa)
IL1R2Interleukin-1 receptor type 2. (387 aa)
LOC103257846Caspase-3; Belongs to the peptidase C14A family. (277 aa)
GNAQGuanine nucleotide-binding protein G(Q) subunit alpha. (359 aa)
C9Complement component C9. (559 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1135 aa)
LOC103274700LOW QUALITY PROTEIN: serpin B13; Belongs to the serpin family. (229 aa)
IL1R1Interleukin-1 receptor type 1. (573 aa)
LAMC2Laminin subunit gamma-2. (1191 aa)
COL4A6Collagen alpha-6(IV) chain isoform X1. (1706 aa)
COL4A5Collagen alpha-5(IV) chain. (622 aa)
ARG1Arginase. (332 aa)
LAMB1Laminin subunit beta-1. (1786 aa)
PRDX1Peroxiredoxin-1. (199 aa)
ITGAMIntegrin alpha-M; Belongs to the integrin alpha chain family. (1152 aa)
PRKCBNon-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (531 aa)
SERPINB8Serpin B8; Belongs to the serpin family. (374 aa)
RAB17Ras-related protein Rab-17 isoform X1. (212 aa)
COL3A1Collagen alpha-1(III) chain. (1466 aa)
LAMB4Laminin subunit beta-4. (1759 aa)
COL4A1Collagen alpha-1(IV) chain. (1621 aa)
PRKACAcAMP-dependent protein kinase catalytic subunit alpha; Belongs to the protein kinase superfamily. (343 aa)
LAMA4Laminin subunit alpha-4. (1777 aa)
CD1AT-cell surface glycoprotein CD1a-like. (307 aa)
IL12BInterleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (326 aa)
C8AComplement component C8 alpha chain. (586 aa)
ENSTSYP00000014000annotation not available (196 aa)
ENSTSYP00000014082annotation not available (103 aa)
ENSTSYP00000014268annotation not available (236 aa)
PRDX2Peroxiredoxin-2. (198 aa)
RAB5BRas-related protein Rab-5B isoform X3. (215 aa)
ITGB2Integrin beta. (769 aa)
COL1A1Collagen alpha-1(I) chain. (1462 aa)
Your Current Organism:
Carlito syrichta
NCBI taxonomy Id: 1868482
Other names: C. syrichta, Philippine tarsier, Tarsius syrichta
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