STRINGSTRING
ENSTSYP00000024401 ENSTSYP00000024401 CRKL CRKL PIK3CB PIK3CB RAPGEF1 RAPGEF1 CRK CRK GRB2 GRB2 CREBBP CREBBP MAPK1 MAPK1 RAP1B RAP1B CDC42 CDC42 TGFB2 TGFB2 ENSTSYP00000031441 ENSTSYP00000031441 AKT1 AKT1 TGFB1 TGFB1 ENSTSYP00000030193 ENSTSYP00000030193 TGFB3 TGFB3 PIK3CD PIK3CD PDGFB PDGFB ARAF ARAF RAP1A RAP1A ARNT2 ARNT2 ETS1 ETS1 MAPK3 MAPK3 PAK6 PAK6 CDKN1A CDKN1A LOC103251021 LOC103251021 LOC103251709 LOC103251709 CUL2 CUL2 PIK3R3 PIK3R3 NRAS NRAS ELOC ELOC ELOB ELOB ENSTSYP00000022968 ENSTSYP00000022968 TGFA TGFA ENSTSYP00000021856 ENSTSYP00000021856 EGLN2 EGLN2 PIK3R1 PIK3R1 RBX1 RBX1 VEGFA VEGFA MAP2K1 MAP2K1 ENSTSYP00000017758 ENSTSYP00000017758 HIF1A HIF1A AKT2 AKT2 ENSTSYP00000014856 ENSTSYP00000014856 PAK4 PAK4 ENSTSYP00000013878 ENSTSYP00000013878 HGF HGF PAK2 PAK2 SLC2A1 SLC2A1 AKT3 AKT3 TFE3 TFE3 BRAF BRAF FH FH RAF1 RAF1 GAB1 GAB1 PRCC PRCC ARNT ARNT PAK1 PAK1 PAK5 PAK5 KRAS KRAS PIK3CA PIK3CA CSDE1 CSDE1 HRAS HRAS PAK3 PAK3 SOS1 SOS1 PTPN11 PTPN11 LOC103269310 LOC103269310 FLCN FLCN EPAS1 EPAS1 EP300 EP300 SOS2 SOS2 MET MET ENSTSYP00000000627 ENSTSYP00000000627
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSTSYP00000024401annotation not available (186 aa)
CRKLCrk-like protein. (303 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X2; Belongs to the PI3/PI4-kinase family. (1070 aa)
RAPGEF1Rap guanine nucleotide exchange factor 1-like. (739 aa)
CRKAdapter molecule crk isoform X1. (304 aa)
GRB2Growth factor receptor-bound protein 2 isoform X1. (217 aa)
CREBBPCREB-binding protein isoform X1. (2433 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (363 aa)
RAP1BRas-related protein Rap-1b isoform X1. (184 aa)
CDC42Cell division control protein 42 homolog. (191 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
ENSTSYP00000031441annotation not available (131 aa)
AKT1Non-specific serine/threonine protein kinase. (393 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (344 aa)
ENSTSYP00000030193annotation not available (164 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1063 aa)
PDGFBPlatelet-derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (229 aa)
ARAFSerine/threonine-protein kinase A-Raf isoform X1. (611 aa)
RAP1ARas-related protein Rap-1A. (184 aa)
ARNT2Aryl hydrocarbon receptor nuclear translocator 2 isoform X2. (706 aa)
ETS1Protein C-ets-1 isoform X1. (485 aa)
MAPK3Mitogen-activated protein kinase. (363 aa)
PAK6Non-specific serine/threonine protein kinase. (681 aa)
CDKN1ACyclin-dependent kinase inhibitor 1. (164 aa)
LOC103251021Egl nine homolog 1. (128 aa)
LOC103251709Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (348 aa)
CUL2Cullin-2; Belongs to the cullin family. (745 aa)
PIK3R3Phosphatidylinositol 3-kinase regulatory subunit gamma isoform X2. (461 aa)
NRASGTPase NRas. (189 aa)
ELOCelongin-C isoform X2; Belongs to the SKP1 family. (112 aa)
ELOBelongin-B. (97 aa)
ENSTSYP00000022968annotation not available (133 aa)
TGFATransforming growth factor alpha. (164 aa)
ENSTSYP00000021856annotation not available (88 aa)
EGLN2Egl nine homolog 2. (405 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (612 aa)
RBX1E3 ubiquitin-protein ligase RBX1 isoform X2. (108 aa)
VEGFAVascular endothelial growth factor A isoform X2; Belongs to the PDGF/VEGF growth factor family. (186 aa)
MAP2K1Dual specificity mitogen-activated protein kinase kinase 1. (381 aa)
ENSTSYP00000017758annotation not available (110 aa)
HIF1AHypoxia-inducible factor 1-alpha isoform X1. (842 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
ENSTSYP00000014856annotation not available (69 aa)
PAK4Non-specific serine/threonine protein kinase. (567 aa)
ENSTSYP00000013878annotation not available (169 aa)
HGFHepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (728 aa)
PAK2Non-specific serine/threonine protein kinase. (524 aa)
SLC2A1Solute carrier family 2, facilitated glucose transporter member 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (460 aa)
AKT3RAC-gamma serine/threonine-protein kinase; Belongs to the protein kinase superfamily. (419 aa)
TFE3Transcription factor E3. (537 aa)
BRAFSerine/threonine-protein kinase B-raf. (760 aa)
FHFumarate hydratase, mitochondrial. (510 aa)
RAF1RAF proto-oncogene serine/threonine-protein kinase isoform X1. (668 aa)
GAB1GRB2-associated-binding protein 1 isoform X1. (700 aa)
PRCCProline-rich protein PRCC isoform X1. (491 aa)
ARNTAryl hydrocarbon receptor nuclear translocator. (761 aa)
PAK1Non-specific serine/threonine protein kinase. (545 aa)
PAK5Non-specific serine/threonine protein kinase. (719 aa)
KRASGTPase KRas isoform X1. (189 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
CSDE1Cold shock domain-containing protein E1 isoform X1. (842 aa)
HRASGTPase HRas isoform X6. (189 aa)
PAK3Serine/threonine-protein kinase PAK 3 isoform X1. (580 aa)
SOS1Son of sevenless homolog 1 isoform X2. (441 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type 11. (532 aa)
LOC103269310Egl nine homolog 3. (145 aa)
FLCNFolliculin. (579 aa)
EPAS1Endothelial PAS domain-containing protein 1. (870 aa)
EP300Histone acetyltransferase p300. (2174 aa)
SOS2Son of sevenless homolog 2 isoform X1. (1318 aa)
METHepatocyte growth factor receptor isoform X1. (1415 aa)
ENSTSYP00000000627annotation not available (167 aa)
Your Current Organism:
Carlito syrichta
NCBI taxonomy Id: 1868482
Other names: C. syrichta, Philippine tarsier, Tarsius syrichta
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