STRINGSTRING
MAX MAX IKBKB IKBKB LOC103259286 LOC103259286 NFKBIA NFKBIA PIK3CA PIK3CA CDKN2B CDKN2B CHUK CHUK TRAF1 TRAF1 POLK POLK CCNE1 CCNE1 NFKB1 NFKB1 LOC103269416 LOC103269416 ITGA6 ITGA6 ENSTSYP00000006890 ENSTSYP00000006890 ENSTSYP00000007331 ENSTSYP00000007331 FN1 FN1 LAMB2 LAMB2 ITGA2 ITGA2 TRAF2 TRAF2 RARB RARB BIRC3 BIRC3 TRAF6 TRAF6 ENSTSYP00000016249 ENSTSYP00000016249 AKT2 AKT2 CKS1B CKS1B BIRC7 BIRC7 ENSTSYP00000014268 ENSTSYP00000014268 LOC103268641 LOC103268641 BCL2L1 BCL2L1 TRAF4 TRAF4 LAMA4 LAMA4 CDK4 CDK4 PTGS2 PTGS2 LAMB4 LAMB4 SECISBP2 SECISBP2 CKS2 CKS2 COL4A1 COL4A1 CDK6 CDK6 CASP9 CASP9 COL4A4 COL4A4 XIAP XIAP RB1 RB1 DDB2 DDB2 LAMA1 LAMA1 LAMA2 LAMA2 LAMC3 LAMC3 COL4A2 COL4A2 ENSTSYP00000035030 ENSTSYP00000035030 LOC103251546 LOC103251546 PIK3CB PIK3CB CDK2 CDK2 BAX BAX CUNH7orf31 CUNH7orf31 PTEN PTEN AKT1 AKT1 MYC MYC LAMB3 LAMB3 LOC103257846 LOC103257846 ITGB1 ITGB1 LAMC2 LAMC2 COL4A6 COL4A6 COL4A5 COL4A5 E2F2 E2F2 ENSTSYP00000009629 ENSTSYP00000009629 LAMB1 LAMB1 AKT3 AKT3 TRAF5 TRAF5 ENSTSYP00000029471 ENSTSYP00000029471 ITGA2B ITGA2B NOS2 NOS2 CDKN1B CDKN1B RXRA RXRA LOC103274909 LOC103274909 PIK3CD PIK3CD CDKN1A CDKN1A BAK1 BAK1 ENSTSYP00000027087 ENSTSYP00000027087 ENSTSYP00000027026 ENSTSYP00000027026 RXRG RXRG IKBKG IKBKG PIK3R3 PIK3R3 PTK2 PTK2 MFF-2 MFF-2 RELA RELA APAF1 APAF1 RXRB RXRB E2F1 E2F1 TP53 TP53 LOC103255326 LOC103255326 LOC103266579 LOC103266579 CCNE2 CCNE2 CCND1 CCND1 TRAF3 TRAF3 LAMC1 LAMC1 ITGAV ITGAV E2F3 E2F3 PIK3R1 PIK3R1 ENSTSYP00000020949 ENSTSYP00000020949 SKP2 SKP2 FHIT FHIT LOC110596190 LOC110596190 LAMA3 LAMA3 LAMA5 LAMA5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MAXProtein max isoform X1. (160 aa)
IKBKBInhibitor of nuclear factor kappa-B kinase subunit beta isoform X1. (756 aa)
LOC103259286Collagen alpha-3(IV) chain-like. (884 aa)
NFKBIANF-kappa-B inhibitor alpha. (282 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
CDKN2BCyclin-dependent kinase 4 inhibitor B. (138 aa)
CHUKInhibitor of nuclear factor kappa-B kinase subunit alpha. (744 aa)
TRAF1TNF receptor-associated factor. (415 aa)
POLKDNA polymerase kappa. (804 aa)
CCNE1G1/S-specific cyclin-E1. (410 aa)
NFKB1Nuclear factor NF-kappa-B p105 subunit isoform X1. (964 aa)
LOC103269416Baculoviral IAP repeat-containing protein 2-like. (340 aa)
ITGA6Integrin alpha-6 isoform X1; Belongs to the integrin alpha chain family. (1130 aa)
ENSTSYP00000006890annotation not available (116 aa)
ENSTSYP00000007331annotation not available (100 aa)
FN1Fibronectin isoform X2. (2450 aa)
LAMB2Laminin subunit beta-2. (1798 aa)
ITGA2LOW QUALITY PROTEIN: integrin alpha-2; Belongs to the integrin alpha chain family. (1175 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa)
RARBRetinoic acid receptor beta isoform X2. (448 aa)
BIRC3Baculoviral IAP repeat-containing protein 3. (603 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (512 aa)
ENSTSYP00000016249annotation not available (98 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
CKS1BCyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa)
BIRC7Baculoviral IAP repeat-containing protein 7. (280 aa)
ENSTSYP00000014268annotation not available (236 aa)
LOC103268641Protein max. (151 aa)
BCL2L1Bcl-2-like protein 1 isoform X1. (233 aa)
TRAF4TNF receptor-associated factor. (470 aa)
LAMA4Laminin subunit alpha-4. (1777 aa)
CDK4Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa)
PTGS2Prostaglandin G/H synthase 2. (604 aa)
LAMB4Laminin subunit beta-4. (1759 aa)
SECISBP2Selenocysteine insertion sequence-binding protein 2. (776 aa)
CKS2Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa)
COL4A1Collagen alpha-1(IV) chain. (1621 aa)
CDK6Cyclin-dependent kinase 6. (264 aa)
CASP9Caspase-9; Belongs to the peptidase C14A family. (410 aa)
COL4A4Collagen alpha-4(IV) chain. (1691 aa)
XIAPE3 ubiquitin-protein ligase XIAP. (497 aa)
RB1Retinoblastoma-associated protein. (929 aa)
DDB2DNA damage-binding protein 2 isoform X1. (415 aa)
LAMA1Laminin subunit alpha-1. (3075 aa)
LAMA2Laminin subunit alpha-2. (2586 aa)
LAMC3Laminin subunit gamma-3. (1431 aa)
COL4A2Collagen alpha-2(IV) chain. (1702 aa)
ENSTSYP00000035030annotation not available (263 aa)
LOC103251546Baculoviral IAP repeat-containing protein 2. (310 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X2; Belongs to the PI3/PI4-kinase family. (1070 aa)
CDK2Cyclin-dependent kinase 2 isoform X1; Belongs to the protein kinase superfamily. (346 aa)
BAXApoptosis regulator BAX isoform X1. (192 aa)
CUNH7orf31Uncharacterized protein C7orf31 homolog. (589 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
AKT1Non-specific serine/threonine protein kinase. (393 aa)
MYCMyc proto-oncogene protein. (376 aa)
LAMB3Laminin subunit beta-3. (1170 aa)
LOC103257846Caspase-3; Belongs to the peptidase C14A family. (277 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (801 aa)
LAMC2Laminin subunit gamma-2. (1191 aa)
COL4A6Collagen alpha-6(IV) chain isoform X1. (1706 aa)
COL4A5Collagen alpha-5(IV) chain. (622 aa)
E2F2Transcription factor E2F2. (423 aa)
ENSTSYP00000009629annotation not available (58 aa)
LAMB1Laminin subunit beta-1. (1786 aa)
AKT3RAC-gamma serine/threonine-protein kinase; Belongs to the protein kinase superfamily. (419 aa)
TRAF5TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (558 aa)
ENSTSYP00000029471annotation not available (82 aa)
ITGA2BIntegrin alpha-IIb; Belongs to the integrin alpha chain family. (851 aa)
NOS2Nitric oxide synthase; Produces nitric oxide (NO). (1153 aa)
CDKN1BLOW QUALITY PROTEIN: cyclin-dependent kinase inhibitor 1B. (197 aa)
RXRARetinoic acid receptor RXR-alpha. (470 aa)
LOC103274909Cytochrome c, somatic; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1063 aa)
CDKN1ACyclin-dependent kinase inhibitor 1. (164 aa)
BAK1Bcl-2 homologous antagonist/killer. (211 aa)
ENSTSYP00000027087annotation not available (52 aa)
ENSTSYP00000027026annotation not available (105 aa)
RXRGRetinoic acid receptor RXR-gamma isoform X1. (463 aa)
IKBKGNF-kappa-B essential modulator. (460 aa)
PIK3R3Phosphatidylinositol 3-kinase regulatory subunit gamma isoform X2. (461 aa)
PTK2Focal adhesion kinase 1 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1096 aa)
MFF-2Mitochondrial fission factor isoform X2. (342 aa)
RELATranscription factor p65. (519 aa)
APAF1Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1246 aa)
RXRBRetinoic acid receptor RXR-beta isoform X2. (533 aa)
E2F1Transcription factor E2F1. (350 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (388 aa)
LOC103255326Cytochrome c 2; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (96 aa)
LOC103266579Growth arrest and DNA damage-inducible protein GADD45 alpha-like. (84 aa)
CCNE2G1/S-specific cyclin-E2 isoform X1; Belongs to the cyclin family. (404 aa)
CCND1G1/S-specific cyclin-D1. (156 aa)
TRAF3TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (568 aa)
LAMC1Laminin subunit gamma-1. (1593 aa)
ITGAVIntegrin alpha-V; Belongs to the integrin alpha chain family. (1041 aa)
E2F3Transcription factor E2F3. (334 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (612 aa)
ENSTSYP00000020949annotation not available (151 aa)
SKP2S-phase kinase-associated protein 2. (436 aa)
FHITBis(5'-adenosyl)-triphosphatase. (149 aa)
LOC110596190Cytochrome c, somatic-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (108 aa)
LAMA3Laminin subunit alpha-3. (892 aa)
LAMA5Laminin subunit alpha-5. (3488 aa)
Your Current Organism:
Carlito syrichta
NCBI taxonomy Id: 1868482
Other names: C. syrichta, Philippine tarsier, Tarsius syrichta
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