STRINGSTRING
WASF3 WASF3 PIP5K1A PIP5K1A SLC22A4 SLC22A4 SLC22A2 SLC22A2 MAPK10 MAPK10 EGFR EGFR PDPK1 PDPK1 TSC1 TSC1 PLA2G4F PLA2G4F PLA2G4D PLA2G4D PLPP1 PLPP1 RAF1 RAF1 DGKE DGKE SLC22A3 SLC22A3 DGKG DGKG EGF EGF LOC103249868 LOC103249868 SLC44A3 SLC44A3 AKT3 AKT3 PDGFC PDGFC DGKD DGKD PRKCB PRKCB PDGFD PDGFD SLC5A7 SLC5A7 MTOR MTOR WASF1 WASF1 PCYT1A PCYT1A SLC22A5 SLC22A5 PLA2G4C PLA2G4C DGKA DGKA RAC3 RAC3 LOC103255477 LOC103255477 WAS WAS AKT2 AKT2 HIF1A HIF1A DGKH DGKH SLC22A1 SLC22A1 RAC1 RAC1 ENSTSYP00000017214 ENSTSYP00000017214 MAP2K1 MAP2K1 RPS6KB1 RPS6KB1 DGKI DGKI GPCPD1 GPCPD1 PLA2G4B PLA2G4B SOS1 SOS1 HRAS HRAS PLD1 PLD1 PLD2 PLD2 CHKB CHKB PIP5K1C PIP5K1C SLC44A1 SLC44A1 PIK3R1 PIK3R1 SOS2 SOS2 SP1 SP1 WASF2 WASF2 PIK3CB PIK3CB SLC44A2 SLC44A2 LOC103270389 LOC103270389 PRKCG PRKCG PDGFA PDGFA GRB2 GRB2 LYPLA1 LYPLA1 RAC2 RAC2 MAPK1 MAPK1 RPS6KB2 RPS6KB2 MAPK9 MAPK9 AKT1 AKT1 PCYT1B PCYT1B LOC103272783 LOC103272783 PIK3CD PIK3CD FOS FOS PDGFB PDGFB ENSTSYP00000029618 ENSTSYP00000029618 PDGFRB PDGFRB PLA2G4A PLA2G4A RHEBL1 RHEBL1 MAPK3 MAPK3 LOC103251709 LOC103251709 MAPK8 MAPK8 ENSTSYP00000025821 ENSTSYP00000025821 CHKA CHKA PIK3R3 PIK3R3 NRAS NRAS RALGDS RALGDS DGKB DGKB LOC103259561 LOC103259561 JMJD7 JMJD7 TSC2 TSC2 ENSTSYP00000021792 ENSTSYP00000021792 CSDE1 CSDE1 SLC44A5 SLC44A5 RHEB RHEB PRKCA PRKCA PLCG1 PLCG1 PIK3CA PIK3CA PLPP3 PLPP3 PDGFRA PDGFRA KRAS KRAS SLC44A4 SLC44A4 CHPT1 CHPT1 DGKK DGKK DGKQ DGKQ
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
WASF3WASP family member 3. (447 aa)
PIP5K1APhosphatidylinositol 4-phosphate 5-kinase type-1 alpha isoform X2. (581 aa)
SLC22A4Solute carrier family 22 member 4. (511 aa)
SLC22A2Solute carrier family 22 member 2. (554 aa)
MAPK10Mitogen-activated protein kinase. (473 aa)
EGFRReceptor protein-tyrosine kinase. (1180 aa)
PDPK13-phosphoinositide-dependent protein kinase 1. (554 aa)
TSC1Hamartin isoform X2. (1164 aa)
PLA2G4FPhospholipase A2. (849 aa)
PLA2G4DPhospholipase A2. (806 aa)
PLPP1Phospholipid phosphatase 1. (287 aa)
RAF1RAF proto-oncogene serine/threonine-protein kinase isoform X1. (668 aa)
DGKEDiacylglycerol kinase. (567 aa)
SLC22A3Solute carrier family 22 member 3. (480 aa)
DGKGDiacylglycerol kinase. (791 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1167 aa)
LOC103249868Cytosolic phospholipase A2 epsilon. (452 aa)
SLC44A3Choline transporter-like protein 3 isoform X1; Belongs to the CTL (choline transporter-like) family. (644 aa)
AKT3RAC-gamma serine/threonine-protein kinase; Belongs to the protein kinase superfamily. (419 aa)
PDGFCPlatelet-derived growth factor C isoform X1; Belongs to the PDGF/VEGF growth factor family. (345 aa)
DGKDDiacylglycerol kinase. (1170 aa)
PRKCBNon-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (531 aa)
PDGFDPlatelet-derived growth factor D. (370 aa)
SLC5A7High affinity choline transporter 1 isoform X1; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (580 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2548 aa)
WASF1wiskott-Aldrich syndrome protein family member 1. (560 aa)
PCYT1ACholine-phosphate cytidylyltransferase A. (381 aa)
SLC22A5Solute carrier family 22 member 5. (565 aa)
PLA2G4CCytosolic phospholipase A2 gamma. (520 aa)
DGKADiacylglycerol kinase. (734 aa)
RAC3Ras-related C3 botulinum toxin substrate 3. (192 aa)
LOC103255477Transcription factor Sp1-like. (259 aa)
WASwiskott-Aldrich syndrome protein. (502 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
HIF1AHypoxia-inducible factor 1-alpha isoform X1. (842 aa)
DGKHDiacylglycerol kinase. (1220 aa)
SLC22A1Solute carrier family 22 member 1 isoform X1. (552 aa)
RAC1Ras-related C3 botulinum toxin substrate 1. (212 aa)
ENSTSYP00000017214annotation not available (178 aa)
MAP2K1Dual specificity mitogen-activated protein kinase kinase 1. (381 aa)
RPS6KB1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa)
DGKIDiacylglycerol kinase. (938 aa)
GPCPD1Glycerophosphocholine phosphodiesterase GPCPD1 isoform X1. (673 aa)
PLA2G4BPhospholipase A2. (781 aa)
SOS1Son of sevenless homolog 1 isoform X2. (441 aa)
HRASGTPase HRas isoform X6. (189 aa)
PLD1Phospholipase. (1075 aa)
PLD2Phospholipase. (934 aa)
CHKBCholine/ethanolamine kinase. (395 aa)
PIP5K1CPhosphatidylinositol 4-phosphate 5-kinase type-1 gamma. (698 aa)
SLC44A1Choline transporter-like protein 1; Belongs to the CTL (choline transporter-like) family. (704 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (612 aa)
SOS2Son of sevenless homolog 2 isoform X1. (1318 aa)
SP1Transcription factor Sp1. (668 aa)
WASF2wiskott-Aldrich syndrome protein family member 2 isoform X1. (497 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X2; Belongs to the PI3/PI4-kinase family. (1070 aa)
SLC44A2Choline transporter-like protein 2; Belongs to the CTL (choline transporter-like) family. (630 aa)
LOC103270389LOW QUALITY PROTEIN: GTP-binding protein Rheb-like. (188 aa)
PRKCGProtein kinase C. (634 aa)
PDGFAPlatelet-derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. (202 aa)
GRB2Growth factor receptor-bound protein 2 isoform X1. (217 aa)
LYPLA1Acyl-protein thioesterase 1 isoform X1. (230 aa)
RAC2Ras-related C3 botulinum toxin substrate 2 isoform X1. (192 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (363 aa)
RPS6KB2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (482 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
AKT1Non-specific serine/threonine protein kinase. (393 aa)
PCYT1BCholine-phosphate cytidylyltransferase B isoform X1. (369 aa)
LOC103272783LOW QUALITY PROTEIN: GTP-binding protein Rheb-like. (178 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1063 aa)
FOSProto-oncogene c-Fos. (379 aa)
PDGFBPlatelet-derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (229 aa)
ENSTSYP00000029618annotation not available (173 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1105 aa)
PLA2G4APhospholipase A2. (749 aa)
RHEBL1GTPase RhebL1. (183 aa)
MAPK3Mitogen-activated protein kinase. (363 aa)
LOC103251709Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (348 aa)
MAPK8Mitogen-activated protein kinase. (384 aa)
ENSTSYP00000025821annotation not available (813 aa)
CHKACholine kinase alpha. (303 aa)
PIK3R3Phosphatidylinositol 3-kinase regulatory subunit gamma isoform X2. (461 aa)
NRASGTPase NRas. (189 aa)
RALGDSRal guanine nucleotide dissociation stimulator. (920 aa)
DGKBDiacylglycerol kinase. (708 aa)
LOC103259561Diacylglycerol kinase. (1082 aa)
JMJD7jmjC domain-containing protein 7. (308 aa)
TSC2LOW QUALITY PROTEIN: tuberin. (1728 aa)
ENSTSYP00000021792annotation not available (85 aa)
CSDE1Cold shock domain-containing protein E1 isoform X1. (842 aa)
SLC44A5Choline transporter-like protein 5; Belongs to the CTL (choline transporter-like) family. (708 aa)
RHEBGTP-binding protein Rheb. (184 aa)
PRKCAProtein kinase C. (614 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1302 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
PLPP3Phospholipid phosphatase 3. (312 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1088 aa)
KRASGTPase KRas isoform X1. (189 aa)
SLC44A4Choline transporter-like protein 4; Belongs to the CTL (choline transporter-like) family. (708 aa)
CHPT1Cholinephosphotransferase 1. (368 aa)
DGKKDiacylglycerol kinase. (953 aa)
DGKQDiacylglycerol kinase. (941 aa)
Your Current Organism:
Carlito syrichta
NCBI taxonomy Id: 1868482
Other names: C. syrichta, Philippine tarsier, Tarsius syrichta
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