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BN69_0102 BN69_0102 gpmA gpmA prs prs pfp pfp BN69_1090 BN69_1090 rpiA rpiA BN69_1880 BN69_1880 glgX glgX glgA glgA glgC glgC BN69_1969 BN69_1969 glgB glgB BN69_1971 BN69_1971 BN69_2031 BN69_2031 BN69_2078 BN69_2078 BN69_2087 BN69_2087 BN69_2088 BN69_2088 BN69_2283 BN69_2283 pgk pgk BN69_2554 BN69_2554 BN69_2555 BN69_2555 BN69_2559 BN69_2559 BN69_2887 BN69_2887 BN69_2936 BN69_2936 eno eno BN69_3458 BN69_3458 tpiA tpiA BN69_3565 BN69_3565 pgi pgi
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
BN69_0102Fructose-1,6-bisphosphatase, class II; Belongs to the FBPase class 2 family. (329 aa)
gpmA2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (207 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (313 aa)
pfpPhosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (406 aa)
BN69_1090UTP-glucose-1-phosphate uridylyltransferase. (294 aa)
rpiARibose-5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (251 aa)
BN69_1880Putative glucokinase. (283 aa)
glgXGlycogen debranching enzyme GlgX; Belongs to the glycosyl hydrolase 13 family. (1406 aa)
glgAGlycogen synthase (Starch synthase); Synthesizes alpha-1,4-glucan chains using ADP-glucose. (486 aa)
glgCGlucose-1-phosphate adenylyltransferase (ADP-glucose pyrophosphorylase / ADP-glucose synthase); Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. (407 aa)
BN69_1969Hypothetical protein. (80 aa)
glgB1,4-alpha-D-glucan 6-glucosyl-transferase (Glycogen-branching enzyme); Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily. (738 aa)
BN69_1971Phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (796 aa)
BN69_2031Phosphoglycerate mutase; Belongs to the Nudix hydrolase family. (364 aa)
BN69_2078Transaldolase. (257 aa)
BN69_2087Transketolase domain protein. (288 aa)
BN69_2088Transketolase, central region. (306 aa)
BN69_2283Glyceraldehyde-3-phosphate dehydrogenase, type I; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (335 aa)
pgkPhosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (401 aa)
BN69_2554Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (674 aa)
BN69_2555Fructose-bisphosphate aldolase, class II, Calvin cycle subtype; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (360 aa)
BN69_2559Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (227 aa)
BN69_2887Ribose-phosphate pyrophosphokinase. (506 aa)
BN69_2936Phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I. (546 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (427 aa)
BN69_3458Phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I. (499 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (250 aa)
BN69_3565Pyruvate kinase; Belongs to the pyruvate kinase family. (480 aa)
pgiGlucose-6-phosphate isomerase (GPI); Belongs to the GPI family. (544 aa)
Your Current Organism:
Methylocystis sp. SC2
NCBI taxonomy Id: 187303
Other names: M. sp. SC2
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