(19 nodes) Pentose phosphate pathway, and Glycolysis network (Methylocystis sp. SC2)

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Your Input:
	BN69_0102	Fructose-1,6-bisphosphatase, class II; Belongs to the FBPase class 2 family. (329 aa)
	gpmA	2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (207 aa)
	prs	Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (313 aa)
	pfp	Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (406 aa)
	rpiA	Ribose-5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (251 aa)
	BN69_2031	Phosphoglycerate mutase; Belongs to the Nudix hydrolase family. (364 aa)
	BN69_2078	Transaldolase. (257 aa)
	BN69_2087	Transketolase domain protein. (288 aa)
	BN69_2088	Transketolase, central region. (306 aa)
	BN69_2283	Glyceraldehyde-3-phosphate dehydrogenase, type I; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (335 aa)
	pgk	Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (401 aa)
	BN69_2554	Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (674 aa)
	BN69_2555	Fructose-bisphosphate aldolase, class II, Calvin cycle subtype; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (360 aa)
	BN69_2559	Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (227 aa)
	BN69_2887	Ribose-phosphate pyrophosphokinase. (506 aa)
	eno	Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (427 aa)
	tpiA	Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (250 aa)
	BN69_3565	Pyruvate kinase; Belongs to the pyruvate kinase family. (480 aa)
	pgi	Glucose-6-phosphate isomerase (GPI); Belongs to the GPI family. (544 aa)

Your Current Organism:

Methylocystis sp. SC2

NCBI taxonomy Id: 187303
Other names: M. sp. SC2

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BN69_0102	BN69_2078	BN69_0102	BN69_2078	Fructose-1,6-bisphosphatase, class II; Belongs to the FBPase class 2 family.	Transaldolase.	0.920
BN69_0102	BN69_2087	BN69_0102	BN69_2087	Fructose-1,6-bisphosphatase, class II; Belongs to the FBPase class 2 family.	Transketolase domain protein.	0.900
BN69_0102	BN69_2088	BN69_0102	BN69_2088	Fructose-1,6-bisphosphatase, class II; Belongs to the FBPase class 2 family.	Transketolase, central region.	0.900
BN69_0102	BN69_2554	BN69_0102	BN69_2554	Fructose-1,6-bisphosphatase, class II; Belongs to the FBPase class 2 family.	Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.	0.968
BN69_0102	BN69_2555	BN69_0102	BN69_2555	Fructose-1,6-bisphosphatase, class II; Belongs to the FBPase class 2 family.	Fructose-bisphosphate aldolase, class II, Calvin cycle subtype; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.	0.929
BN69_0102	pfp	BN69_0102	BN69_0769	Fructose-1,6-bisphosphatase, class II; Belongs to the FBPase class 2 family.	Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.	0.926
BN69_0102	pgi	BN69_0102	BN69_3623	Fructose-1,6-bisphosphatase, class II; Belongs to the FBPase class 2 family.	Glucose-6-phosphate isomerase (GPI); Belongs to the GPI family.	0.925
BN69_2031	BN69_2078	BN69_2031	BN69_2078	Phosphoglycerate mutase; Belongs to the Nudix hydrolase family.	Transaldolase.	0.837
BN69_2031	BN69_2087	BN69_2031	BN69_2087	Phosphoglycerate mutase; Belongs to the Nudix hydrolase family.	Transketolase domain protein.	0.807
BN69_2031	BN69_2088	BN69_2031	BN69_2088	Phosphoglycerate mutase; Belongs to the Nudix hydrolase family.	Transketolase, central region.	0.808
BN69_2031	BN69_2554	BN69_2031	BN69_2554	Phosphoglycerate mutase; Belongs to the Nudix hydrolase family.	Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.	0.883
BN69_2031	BN69_2555	BN69_2031	BN69_2555	Phosphoglycerate mutase; Belongs to the Nudix hydrolase family.	Fructose-bisphosphate aldolase, class II, Calvin cycle subtype; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.	0.834
BN69_2031	BN69_3565	BN69_2031	BN69_3565	Phosphoglycerate mutase; Belongs to the Nudix hydrolase family.	Pyruvate kinase; Belongs to the pyruvate kinase family.	0.413
BN69_2031	eno	BN69_2031	BN69_2963	Phosphoglycerate mutase; Belongs to the Nudix hydrolase family.	Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.	0.912
BN69_2031	gpmA	BN69_2031	BN69_0311	Phosphoglycerate mutase; Belongs to the Nudix hydrolase family.	2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily.	0.977
BN69_2031	pgi	BN69_2031	BN69_3623	Phosphoglycerate mutase; Belongs to the Nudix hydrolase family.	Glucose-6-phosphate isomerase (GPI); Belongs to the GPI family.	0.872
BN69_2031	pgk	BN69_2031	BN69_2284	Phosphoglycerate mutase; Belongs to the Nudix hydrolase family.	Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family.	0.927
BN69_2031	tpiA	BN69_2031	BN69_3512	Phosphoglycerate mutase; Belongs to the Nudix hydrolase family.	Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.	0.835
BN69_2078	BN69_0102	BN69_2078	BN69_0102	Transaldolase.	Fructose-1,6-bisphosphatase, class II; Belongs to the FBPase class 2 family.	0.920
BN69_2078	BN69_2031	BN69_2078	BN69_2031	Transaldolase.	Phosphoglycerate mutase; Belongs to the Nudix hydrolase family.	0.837