STRINGSTRING
BEN71_07435 BEN71_07435 guaB guaB rdgB rdgB xpt xpt ppnP ppnP upp upp BEN71_18835 BEN71_18835 guaD guaD hpt hpt BEN71_08250 BEN71_08250 purA purA ppnP-2 ppnP-2 BEN71_08820 BEN71_08820 BEN71_13880 BEN71_13880 guaA guaA BEN71_09860 BEN71_09860 surE surE BEN71_11940 BEN71_11940
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BEN71_07435Unannotated protein; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (462 aa)
guaBUnannotated protein; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (488 aa)
rdgBUnannotated protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (208 aa)
xptUnannotated protein; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. (191 aa)
ppnPUnannotated protein; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions. (107 aa)
uppUnannotated protein; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (211 aa)
BEN71_18835Unannotated protein; Belongs to the 5'-nucleotidase family. (630 aa)
guaDUnannotated protein; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. (438 aa)
hptUnannotated protein; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (175 aa)
BEN71_08250Unannotated protein; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. (333 aa)
purAUnannotated protein; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (439 aa)
ppnP-2Unannotated protein; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions. (105 aa)
BEN71_08820Unannotated protein. (154 aa)
BEN71_13880Unannotated protein. (180 aa)
guaAUnannotated protein; Catalyzes the synthesis of GMP from XMP. (522 aa)
BEN71_09860Unannotated protein. (164 aa)
surEUnannotated protein; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (261 aa)
BEN71_11940Unannotated protein. (238 aa)
Your Current Organism:
Acinetobacter wuhouensis
NCBI taxonomy Id: 1879050
Other names: A. wuhouensis, Acinetobacter sp. WCHA60, Acinetobacter sp. WCHA62, Acinetobacter wuhouensis Hu et al. 2018, CCTCC AB 2016204, CCTCC:AB:2016204, KCTC 52505, strain WCHA60
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