(33 nodes) Butanoate metabolism, and Acyl-CoA dehydrogenase/oxidase C-terminal network (Hydrogenophaga sp. H7)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	OPF65218.1	3-hydroxybutyryl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (283 aa)
	OPF65244.1	acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (598 aa)
	OPF65246.1	3-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (799 aa)
	OPF65247.1	acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (401 aa)
	OPF65250.1	enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (254 aa)
	OPF65373.1	enoyl-CoA hydratase; Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family. (262 aa)
	OPF65374.1	2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA isomerase; Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family. (256 aa)
	OPF65427.1	3-oxoadipyl-CoA thiolase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (400 aa)
	OPF65655.1	3-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (702 aa)
	OPF65656.1	acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (391 aa)
	OPF65660.1	acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (607 aa)
	OPF65665.1	DNA alkylation response protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (550 aa)
	OPF64430.1	pimeloyl-CoA dehydrogenase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (393 aa)
	OPF64431.1	acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (371 aa)
	OPF63689.1	acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa)
	OPF63839.1	enoyl-CoA hydratase; Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family. (259 aa)
	OPF63840.1	3-hydroxyacyl-CoA dehydrogenase; Converts 3-hydroxyadipyl-CoA to beta-ketoadipyl-CoA in phenylacetate degradation; Derived by automated computational analysis using gene prediction method: Protein Homology. (506 aa)
	OPF63158.1	enoyl-CoA hydratase; Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (257 aa)
	OPF63500.1	3-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (719 aa)
	OPF63501.1	acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (401 aa)
	OPF63502.1	acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (388 aa)
	OPF63512.1	enoyl-CoA hydratase; Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family. (298 aa)
	OPF62915.1	acetoacetate--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (700 aa)
	OPF62356.1	acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (396 aa)
	OPF62658.1	enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (281 aa)
	OPF61995.1	acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (416 aa)
	OPF62110.1	3-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (305 aa)
	OPF61790.1	succinyl-CoA--3-ketoacid-CoA transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (233 aa)
	OPF61791.1	succinyl-CoA--3-ketoacid-CoA transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (212 aa)
	OPF61925.1	Multifunctional fatty acid oxidation complex subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (718 aa)
	OPF64806.1	acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (394 aa)
	OPF64763.1	acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (394 aa)
	OPF64576.1	3-hydroxyisobutyryl-CoA hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (364 aa)

Your Current Organism:

Hydrogenophaga sp. H7

NCBI taxonomy Id: 1882399
Other names: H. sp. H7

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
OPF61790.1	OPF61791.1	BC358_17270	BC358_17275	succinyl-CoA--3-ketoacid-CoA transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	succinyl-CoA--3-ketoacid-CoA transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999
OPF61790.1	OPF61925.1	BC358_17270	BC358_18100	succinyl-CoA--3-ketoacid-CoA transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Multifunctional fatty acid oxidation complex subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.869
OPF61790.1	OPF61995.1	BC358_17270	BC358_15230	succinyl-CoA--3-ketoacid-CoA transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family.	0.904
OPF61790.1	OPF62110.1	BC358_17270	BC358_15890	succinyl-CoA--3-ketoacid-CoA transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	3-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.903
OPF61790.1	OPF62356.1	BC358_17270	BC358_13215	succinyl-CoA--3-ketoacid-CoA transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family.	0.904
OPF61790.1	OPF62915.1	BC358_17270	BC358_12040	succinyl-CoA--3-ketoacid-CoA transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	acetoacetate--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.893
OPF61790.1	OPF63500.1	BC358_17270	BC358_10885	succinyl-CoA--3-ketoacid-CoA transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	3-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.933
OPF61790.1	OPF63501.1	BC358_17270	BC358_10890	succinyl-CoA--3-ketoacid-CoA transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family.	0.870
OPF61790.1	OPF63689.1	BC358_17270	BC358_07165	succinyl-CoA--3-ketoacid-CoA transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family.	0.870
OPF61790.1	OPF63840.1	BC358_17270	BC358_08030	succinyl-CoA--3-ketoacid-CoA transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	3-hydroxyacyl-CoA dehydrogenase; Converts 3-hydroxyadipyl-CoA to beta-ketoadipyl-CoA in phenylacetate degradation; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.900
OPF61790.1	OPF64763.1	BC358_17270	BC358_20560	succinyl-CoA--3-ketoacid-CoA transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family.	0.904
OPF61790.1	OPF64806.1	BC358_17270	BC358_19855	succinyl-CoA--3-ketoacid-CoA transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family.	0.793
OPF61790.1	OPF65218.1	BC358_17270	BC358_01265	succinyl-CoA--3-ketoacid-CoA transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	3-hydroxybutyryl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.900
OPF61790.1	OPF65246.1	BC358_17270	BC358_01430	succinyl-CoA--3-ketoacid-CoA transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	3-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.933
OPF61790.1	OPF65247.1	BC358_17270	BC358_01435	succinyl-CoA--3-ketoacid-CoA transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family.	0.904
OPF61790.1	OPF65427.1	BC358_17270	BC358_02425	succinyl-CoA--3-ketoacid-CoA transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	3-oxoadipyl-CoA thiolase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family.	0.811
OPF61790.1	OPF65655.1	BC358_17270	BC358_03720	succinyl-CoA--3-ketoacid-CoA transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	3-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.933
OPF61790.1	OPF65656.1	BC358_17270	BC358_03725	succinyl-CoA--3-ketoacid-CoA transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family.	0.910
OPF61791.1	OPF61790.1	BC358_17275	BC358_17270	succinyl-CoA--3-ketoacid-CoA transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	succinyl-CoA--3-ketoacid-CoA transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999
OPF61791.1	OPF61925.1	BC358_17275	BC358_18100	succinyl-CoA--3-ketoacid-CoA transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Multifunctional fatty acid oxidation complex subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.876