(99 nodes) Microtubule cytoskeleton network (Testicularia cyperi)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A317XH87	Uncharacterized protein. (1233 aa)
	A0A317XQ72	Uncharacterized protein. (242 aa)
	PAC1	Nuclear distribution protein PAC1; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) transport from the hyphal tip. Required for localization of dynein to the mitotic spindle poles. Recruits additional proteins to the dynein complex at SPBs; Belongs to the WD repeat LIS1/nudF family. (455 aa)
	A0A317XQK4	Putative CDC10-septin; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (329 aa)
	A0A317XQM4	Serine/threonine-protein kinase. (959 aa)
	A0A317XQR7	P-loop containing nucleoside triphosphate hydrolase protein; Belongs to the small GTPase superfamily. Arf family. (191 aa)
	A0A317XQY8	Kinesin-domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1235 aa)
	A0A317XR25	Uncharacterized protein. (1063 aa)
	A0A317XR36	Putative nudC protein. (192 aa)
	A0A317XRR5	Uncharacterized protein. (1252 aa)
	A0A317XRT0	Spindle pole body component. (1042 aa)
	A0A317XRU8	AIP3-domain-containing protein. (1324 aa)
	A0A317XRY4	Uncharacterized protein. (2356 aa)
	A0A317XS11	Csm1 domain-containing protein. (506 aa)
	A0A317XS48	Uncharacterized protein. (1644 aa)
	A0A317XSD8	SUN domain-containing protein. (801 aa)
	A0A317XSH5	Peptidase C50 domain-containing protein. (2092 aa)
	A0A317XSJ5	Cytoplasmic dynein heavy chain 1. (3245 aa)
	A0A317XSQ6	TBC-domain-containing protein. (442 aa)
	A0A317XSU3	CS domain-containing protein. (943 aa)
	A0A317XSX2	Uncharacterized protein. (426 aa)
	A0A317XT18	Uncharacterized protein. (833 aa)
	A0A317XT74	Putative casein kinase-1 hhp1; Belongs to the protein kinase superfamily. (377 aa)
	A0A317XT77	Kinesin-domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1595 aa)
	A0A317XT78	SPT2-domain-containing protein. (632 aa)
	A0A317XTF5	Uncharacterized protein. (536 aa)
	A0A317XTR1	Uncharacterized protein. (891 aa)
	A0A317XTT4	Actin-like ATPase domain-containing protein; Belongs to the actin family. (737 aa)
	A0A317XU38	Uncharacterized protein. (898 aa)
	A0A317XUC1	Mo25-like protein. (391 aa)
	A0A317XUD5	Putative CDC31-spindle pole body component, centrin. (194 aa)
	A0A317XUN5	CLASP_N domain-containing protein. (861 aa)
	A0A317XUV2	Putative dynactin Arp1 p25 subunit RO12. (210 aa)
	A0A317XVI4	Uncharacterized protein. (173 aa)
	A0A317XVX8	Uncharacterized protein. (1278 aa)
	A0A317XVY2	Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...] (210 aa)
	A0A317XW67	Putative IPL1-ser/thr protein kinase. (504 aa)
	A0A317XWN5	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (550 aa)
	A0A317XWT7	Uncharacterized protein. (280 aa)
	A0A317XX68	Uncharacterized protein. (544 aa)
	A0A317XXL6	CAP-Gly domain-containing protein. (270 aa)
	A0A317XXM9	DASH complex, subunit Dad4. (80 aa)
	A0A317XYA2	Putative translationally-controlled tumor protein; Belongs to the TCTP family. (167 aa)
	A0A317XZE8	CAP-Gly domain-containing protein. (1623 aa)
	A0A317XZI0	Tubulin gamma chain; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. (453 aa)
	A0A317XZK8	Uncharacterized protein. (468 aa)
	A0A317XZT9	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (463 aa)
	A0A317XZW9	Robl_LC7 domain-containing protein. (218 aa)
	A0A317Y046	Uncharacterized protein. (1087 aa)
	A0A317Y0E4	Putative DNM1-dynamin-related GTPase; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (852 aa)
	A0A317Y0F3	Uncharacterized protein. (133 aa)
	A0A317Y0P4	Putative RPN8-26S proteasome regulatory subunit. (333 aa)
	A0A317Y0Z1	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (448 aa)
	A0A317Y1F1	RNI-like protein. (644 aa)
	A0A317Y1M7	Protein phosphatase PP2A regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (468 aa)
	A0A317XE86	PUA-domain-containing protein. (248 aa)
	A0A317XEN9	Kinesin-domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1229 aa)
	A0A317XFD6	Kinesin-domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1090 aa)
	A0A317XGG8	Checkpoint protein; Belongs to the HUS1 family. (283 aa)
	A0A317XH65	Putative TEM1-GTP-binding protein of the ras superfamily. (213 aa)
	A0A317XPX0	Putative MOB1 protein. (217 aa)
	A0A317XPW3	INCENP_ARK-bind domain-containing protein. (100 aa)
	A0A317XPV2	Uncharacterized protein. (200 aa)
	A0A317XPS2	Uncharacterized protein. (157 aa)
	A0A317XPP7	Trimeric LpxA-like protein. (245 aa)
	A0A317XPN1	Uncharacterized protein. (449 aa)
	A0A317XPM7	GCP_C_terminal domain-containing protein. (1228 aa)
	A0A317XPF0	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (475 aa)
	A0A317XP89	Kinesin-domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1978 aa)
	A0A317XP41	Cytoplasmic dynein heavy chain 2. (1582 aa)
	A0A317XNP8	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (736 aa)
	A0A317XNJ3	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (972 aa)
	A0A317XNG8	Uncharacterized protein. (1323 aa)
	A0A317XNF8	ARM repeat-containing protein. (2215 aa)
	A0A317XNF2	Putative ser/thr protein phosphatase 2A regulatory subunit A. (593 aa)
	A0A317XN88	Uncharacterized protein. (360 aa)
	A0A317XN64	Putative VPS1-member of the dynamin family of GTPase; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (696 aa)
	A0A317XN28	Uncharacterized protein. (88 aa)
	A0A317XMZ6	Putative cell division control protein CDC3; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (426 aa)
	A0A317XMH4	Uncharacterized protein. (958 aa)
	A0A317XM78	Uncharacterized protein. (1002 aa)
	A0A317XM28	Uncharacterized protein. (1304 aa)
	A0A317XLC3	Septin; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (359 aa)
	A0A317XL70	Kinesin-domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1096 aa)
	A0A317XKX0	WD40 repeat-like protein. (823 aa)
	A0A317XKV3	Uncharacterized protein. (1278 aa)
	A0A317XJX5	Uncharacterized protein. (685 aa)
	A0A317XJW5	DUF667 domain-containing protein. (313 aa)
	A0A317XJ60	Uncharacterized protein. (161 aa)
	A0A317XJ49	Uncharacterized protein. (1487 aa)
	A0A317XIZ0	DUF171-domain-containing protein. (469 aa)
	A0A317XIX7	Uncharacterized protein. (568 aa)
	A0A317XIV4	Kinesin-domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (690 aa)
	A0A317XIU8	Dynein light chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures. (109 aa)
	A0A317XIT9	DLIC-domain-containing protein. (794 aa)
	A0A317XI46	Uncharacterized protein. (741 aa)
	A0A317XHM5	Putative rRNA pseudouridine synthase. (504 aa)
	A0A317XHG7	Ima1_N domain-containing protein. (633 aa)
	A0A317XQ56	ARM repeat-containing protein. (924 aa)

Your Current Organism:

Testicularia cyperi

NCBI taxonomy Id: 1882483
Other names: T. cyperi

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A317XE86	A0A317XIZ0	A0A317XE86	A0A317XIZ0	PUA-domain-containing protein.	DUF171-domain-containing protein.	0.640
A0A317XEN9	A0A317XFD6	A0A317XEN9	A0A317XFD6	Kinesin-domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin-domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.953
A0A317XEN9	A0A317XH65	A0A317XEN9	A0A317XH65	Kinesin-domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Putative TEM1-GTP-binding protein of the ras superfamily.	0.461
A0A317XEN9	A0A317XIU8	A0A317XEN9	A0A317XIU8	Kinesin-domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Dynein light chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures.	0.416
A0A317XEN9	A0A317XIV4	A0A317XEN9	A0A317XIV4	Kinesin-domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin-domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.992
A0A317XEN9	A0A317XJ49	A0A317XEN9	A0A317XJ49	Kinesin-domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Uncharacterized protein.	0.410
A0A317XEN9	A0A317XJX5	A0A317XEN9	A0A317XJX5	Kinesin-domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Uncharacterized protein.	0.401
A0A317XEN9	A0A317XKV3	A0A317XEN9	A0A317XKV3	Kinesin-domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Uncharacterized protein.	0.545
A0A317XEN9	A0A317XL70	A0A317XEN9	A0A317XL70	Kinesin-domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin-domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.952
A0A317XEN9	A0A317XNF8	A0A317XEN9	A0A317XNF8	Kinesin-domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	ARM repeat-containing protein.	0.624
A0A317XEN9	A0A317XNG8	A0A317XEN9	A0A317XNG8	Kinesin-domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Uncharacterized protein.	0.482
A0A317XEN9	A0A317XP41	A0A317XEN9	A0A317XP41	Kinesin-domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Cytoplasmic dynein heavy chain 2.	0.685
A0A317XEN9	A0A317XP89	A0A317XEN9	A0A317XP89	Kinesin-domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin-domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.914
A0A317XEN9	A0A317XPF0	A0A317XEN9	A0A317XPF0	Kinesin-domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.823
A0A317XEN9	A0A317XPP7	A0A317XEN9	A0A317XPP7	Kinesin-domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Trimeric LpxA-like protein.	0.554
A0A317XEN9	A0A317XQM4	A0A317XEN9	A0A317XQM4	Kinesin-domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Serine/threonine-protein kinase.	0.809
A0A317XEN9	A0A317XQY8	A0A317XEN9	A0A317XQY8	Kinesin-domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin-domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.969
A0A317XEN9	A0A317XR25	A0A317XEN9	A0A317XR25	Kinesin-domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Uncharacterized protein.	0.965
A0A317XEN9	A0A317XRT0	A0A317XEN9	A0A317XRT0	Kinesin-domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Spindle pole body component.	0.484
A0A317XEN9	A0A317XSH5	A0A317XEN9	A0A317XSH5	Kinesin-domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Peptidase C50 domain-containing protein.	0.905