(48 nodes) RNA polymerase II, holoenzyme network (Testicularia cyperi)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

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protein homology

Your Input:
	A0A317Y0F0	Putative 25 kd subunit of DNA-directed RNA polymerases I, II and III. (208 aa)
	A0A317Y049	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1782 aa)
	A0A317XZQ0	Uncharacterized protein. (426 aa)
	A0A317XZE3	TAF domain-containing protein. (710 aa)
	A0A317XZD1	WD40 repeat-like protein. (444 aa)
	A0A317XZA8	Ssl1-domain-containing protein. (566 aa)
	A0A317XYY1	Putative DNA-directed RNA polymerase II chain Rpb7. (170 aa)
	A0A317XYA0	Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. (249 aa)
	A0A317XXF5	Uncharacterized protein. (382 aa)
	BCV70DRAFT_607	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1245 aa)
	A0A317XX99	Putative Rpo26-18kD subunit of DNA-directed RNA polymerases I, II, III. (138 aa)
	A0A317XVZ3	CDC73-domain-containing protein. (475 aa)
	A0A317XV30	Uncharacterized protein. (215 aa)
	A0A317XV28	Uncharacterized protein. (119 aa)
	A0A317XUX6	Cyclin-like protein; Belongs to the cyclin family. (531 aa)
	A0A317XUQ2	Uncharacterized protein. (71 aa)
	A0A317XUA1	Putative TATA-box-binding factor TBP. (245 aa)
	A0A317XU23	RBP11-like subunits of RNA polymerase. (154 aa)
	A0A317XTX2	Uncharacterized protein. (1471 aa)
	A0A317XTW9	BTP domain-containing protein. (793 aa)
	A0A317XTR0	TAFII28-domain-containing protein. (438 aa)
	A0A317XTG4	TFIID_20kDa domain-containing protein. (897 aa)
	A0A317XS74	Uncharacterized protein. (815 aa)
	A0A317XS60	TAFII55_N domain-containing protein. (673 aa)
	A0A317XRZ0	Putative RAD3-DNA helicase/ATPase. (836 aa)
	A0A317XRL6	Transcription factor Tfb4. (428 aa)
	A0A317XR21	CBS domain-containing protein. (380 aa)
	A0A317XQJ5	TFIID-31kDa-domain-containing protein. (283 aa)
	A0A317XPT3	RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (500 aa)
	A0A317XPS4	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (133 aa)
	A0A317XPM2	Nucleotide excision repair, TFIIH, subunit. (65 aa)
	A0A317XP99	Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (95 aa)
	A0A317XP37	Endo/exonuclease/phosphatase domain-containing protein. (853 aa)
	A0A317XNU5	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (159 aa)
	A0A317XNI1	HTH TFE/IIEalpha-type domain-containing protein. (446 aa)
	A0A317XNB0	Uncharacterized protein. (1864 aa)
	A0A317XMX0	Putative KIN28-cyclin-dependent ser/thr protein kinase; Belongs to the protein kinase superfamily. (379 aa)
	A0A317XLW9	Insert subdomain of RNA polymerase alpha subunit. (376 aa)
	A0A317XLU4	Uncharacterized protein. (738 aa)
	A0A317XLE6	TAF4 domain-containing protein. (507 aa)
	A0A317XIG3	Paf1-domain-containing protein. (683 aa)
	A0A317XHW7	Uncharacterized protein. (305 aa)
	A0A317XGZ1	CDK-activating kinase assembly factor. (401 aa)
	A0A317XFW0	Uncharacterized protein. (1237 aa)
	A0A317XEZ6	Putative SSL2-DNA helicase. (934 aa)
	A0A317XEZ2	RPOL4c domain-containing protein. (165 aa)
	A0A317Y174	WD40 repeat-like protein. (1036 aa)
	A0A317Y0H2	Plus3 domain-containing protein. (671 aa)

Your Current Organism:

Testicularia cyperi

NCBI taxonomy Id: 1882483
Other names: T. cyperi

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A317XEZ2	A0A317XEZ6	A0A317XEZ2	A0A317XEZ6	RPOL4c domain-containing protein.	Putative SSL2-DNA helicase.	0.966
A0A317XEZ2	A0A317XFW0	A0A317XEZ2	A0A317XFW0	RPOL4c domain-containing protein.	Uncharacterized protein.	0.852
A0A317XEZ2	A0A317XGZ1	A0A317XEZ2	A0A317XGZ1	RPOL4c domain-containing protein.	CDK-activating kinase assembly factor.	0.976
A0A317XEZ2	A0A317XHW7	A0A317XEZ2	A0A317XHW7	RPOL4c domain-containing protein.	Uncharacterized protein.	0.895
A0A317XEZ2	A0A317XIG3	A0A317XEZ2	A0A317XIG3	RPOL4c domain-containing protein.	Paf1-domain-containing protein.	0.897
A0A317XEZ2	A0A317XLE6	A0A317XEZ2	A0A317XLE6	RPOL4c domain-containing protein.	TAF4 domain-containing protein.	0.846
A0A317XEZ2	A0A317XLU4	A0A317XEZ2	A0A317XLU4	RPOL4c domain-containing protein.	Uncharacterized protein.	0.961
A0A317XEZ2	A0A317XLW9	A0A317XEZ2	A0A317XLW9	RPOL4c domain-containing protein.	Insert subdomain of RNA polymerase alpha subunit.	0.999
A0A317XEZ2	A0A317XMX0	A0A317XEZ2	A0A317XMX0	RPOL4c domain-containing protein.	Putative KIN28-cyclin-dependent ser/thr protein kinase; Belongs to the protein kinase superfamily.	0.946
A0A317XEZ2	A0A317XNB0	A0A317XEZ2	A0A317XNB0	RPOL4c domain-containing protein.	Uncharacterized protein.	0.868
A0A317XEZ2	A0A317XNI1	A0A317XEZ2	A0A317XNI1	RPOL4c domain-containing protein.	HTH TFE/IIEalpha-type domain-containing protein.	0.969
A0A317XEZ2	A0A317XNU5	A0A317XEZ2	A0A317XNU5	RPOL4c domain-containing protein.	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.	0.999
A0A317XEZ2	A0A317XP99	A0A317XEZ2	A0A317XP99	RPOL4c domain-containing protein.	Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family.	0.962
A0A317XEZ2	A0A317XPM2	A0A317XEZ2	A0A317XPM2	RPOL4c domain-containing protein.	Nucleotide excision repair, TFIIH, subunit.	0.839
A0A317XEZ2	A0A317XPS4	A0A317XEZ2	A0A317XPS4	RPOL4c domain-containing protein.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.	0.999
A0A317XEZ2	A0A317XPT3	A0A317XEZ2	A0A317XPT3	RPOL4c domain-containing protein.	RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	0.959
A0A317XEZ2	A0A317XQJ5	A0A317XEZ2	A0A317XQJ5	RPOL4c domain-containing protein.	TFIID-31kDa-domain-containing protein.	0.849
A0A317XEZ2	A0A317XR21	A0A317XEZ2	A0A317XR21	RPOL4c domain-containing protein.	CBS domain-containing protein.	0.860
A0A317XEZ2	A0A317XRL6	A0A317XEZ2	A0A317XRL6	RPOL4c domain-containing protein.	Transcription factor Tfb4.	0.962
A0A317XEZ2	A0A317XRZ0	A0A317XEZ2	A0A317XRZ0	RPOL4c domain-containing protein.	Putative RAD3-DNA helicase/ATPase.	0.964