(23 nodes) U2-type catalytic step 2 spliceosome, and Spliceosomal conformational changes to generate catalytic conformation network (Egretta garzetta)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Z169_13360	Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16. (1127 aa)
	SYF2	Pre-mRNA-splicing factor syf2. (199 aa)
	PRPF18	Pre-mRNA-splicing factor 18. (320 aa)
	PPIE	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (166 aa)
	ISY1	Pre-mRNA-splicing factor ISY1. (219 aa)
	CCDC94	Coiled-coil domain-containing protein 94. (181 aa)
	PLRG1	Pleiotropic regulator 1. (513 aa)
	Z169_07775	Pre-mRNA-splicing factor CWC25. (417 aa)
	SNRNP48	U11/U12 small nuclear ribonucleoprotein 48 kDa protein. (238 aa)
	Z169_05338	Pre-mRNA-splicing factor SPF27. (128 aa)
	AQR	Intron-binding protein aquarius. (1370 aa)
	ZNF830	Zinc finger protein 830. (290 aa)
	CDC5L	Cell division cycle 5-like. (789 aa)
	RBM22	Pre-mRNA-splicing factor RBM22. (402 aa)
	Z169_03922	Crooked neck-like 1. (685 aa)
	DHX33	Putative ATP-dependent RNA helicase DHX33. (612 aa)
	CDC40	Pre-mRNA-processing factor 17. (520 aa)
	CTNNBL1	Beta-catenin-like 1. (554 aa)
	CWC15	Protein CWC15 A. (230 aa)
	SNW1	SNW domain-containing protein 1. (538 aa)
	BUD31	Protein BUD31. (144 aa)
	CWC22	Pre-mRNA-splicing factor CWC22. (868 aa)
	SLU7	Pre-mRNA-splicing factor SLU7. (581 aa)

Your Current Organism:

Egretta garzetta

NCBI taxonomy Id: 188379
Other names: E. garzetta, little egret

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AQR	BUD31	A0A091J6C7	A0A091KDE5	Intron-binding protein aquarius.	Protein BUD31.	0.978
AQR	CCDC94	A0A091J6C7	A0A091IZQ1	Intron-binding protein aquarius.	Coiled-coil domain-containing protein 94.	0.802
AQR	CDC40	A0A091J6C7	A0A091JJV6	Intron-binding protein aquarius.	Pre-mRNA-processing factor 17.	0.975
AQR	CDC5L	A0A091J6C7	A0A091J7L5	Intron-binding protein aquarius.	Cell division cycle 5-like.	0.985
AQR	CTNNBL1	A0A091J6C7	A0A091JK34	Intron-binding protein aquarius.	Beta-catenin-like 1.	0.501
AQR	CWC15	A0A091J6C7	A0A091JM97	Intron-binding protein aquarius.	Protein CWC15 A.	0.891
AQR	CWC22	A0A091J6C7	A0A091KDJ7	Intron-binding protein aquarius.	Pre-mRNA-splicing factor CWC22.	0.810
AQR	DHX33	A0A091J6C7	A0A091JJC6	Intron-binding protein aquarius.	Putative ATP-dependent RNA helicase DHX33.	0.646
AQR	ISY1	A0A091J6C7	A0A091IZJ9	Intron-binding protein aquarius.	Pre-mRNA-splicing factor ISY1.	0.983
AQR	PLRG1	A0A091J6C7	A0A091J2W7	Intron-binding protein aquarius.	Pleiotropic regulator 1.	0.907
AQR	PPIE	A0A091J6C7	A0A091ITH1	Intron-binding protein aquarius.	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.	0.980
AQR	RBM22	A0A091J6C7	A0A091JBK8	Intron-binding protein aquarius.	Pre-mRNA-splicing factor RBM22.	0.983
AQR	SLU7	A0A091J6C7	A0A091KGB8	Intron-binding protein aquarius.	Pre-mRNA-splicing factor SLU7.	0.828
AQR	SNRNP48	A0A091J6C7	A0A091J5P7	Intron-binding protein aquarius.	U11/U12 small nuclear ribonucleoprotein 48 kDa protein.	0.551
AQR	SNW1	A0A091J6C7	A0A091JQZ2	Intron-binding protein aquarius.	SNW domain-containing protein 1.	0.977
AQR	SYF2	A0A091J6C7	A0A091IR65	Intron-binding protein aquarius.	Pre-mRNA-splicing factor syf2.	0.845
AQR	Z169_03922	A0A091J6C7	A0A091JI33	Intron-binding protein aquarius.	Crooked neck-like 1.	0.991
AQR	Z169_05338	A0A091J6C7	A0A091J638	Intron-binding protein aquarius.	Pre-mRNA-splicing factor SPF27.	0.939
AQR	Z169_07775	A0A091J6C7	A0A091J451	Intron-binding protein aquarius.	Pre-mRNA-splicing factor CWC25.	0.502
AQR	Z169_13360	A0A091J6C7	A0A091IMC2	Intron-binding protein aquarius.	Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16.	0.538