STRINGSTRING
PAFAH1B1 PAFAH1B1 PARD3 PARD3 MYO6 MYO6 Z169_14933 Z169_14933 CRIP2 CRIP2 Z169_00608 Z169_00608 SEPT4 SEPT4 UNC13C UNC13C MYO1B MYO1B EXOC3 EXOC3 NF2 NF2 PFN4 PFN4 MELK MELK SEPT11 SEPT11 RHOH RHOH Z169_02852 Z169_02852 Z169_04862 Z169_04862 FNBP1L FNBP1L Z169_08280 Z169_08280 SEPT9 SEPT9 TRAF6 TRAF6 Z169_11467 Z169_11467 UNC13B UNC13B COTL1 COTL1 CAV1 CAV1 CAPZA2 CAPZA2 RHOBTB1 RHOBTB1 STOX1 STOX1 CAPZB CAPZB SPIRE1 SPIRE1 CDH2 CDH2 Z169_13722 Z169_13722 MYRIP MYRIP GNAI1 GNAI1 EPB41 EPB41 ECT2 ECT2 NRBP1 NRBP1 INSC INSC Z169_00673 Z169_00673 DFNB59 DFNB59 Z169_11631 Z169_11631 Z169_02256 Z169_02256 EPB41L2 EPB41L2 SEPT2 SEPT2 ARV1 ARV1 Z169_14726 Z169_14726 PARD6B PARD6B CIB2 CIB2 Z169_06680 Z169_06680 CTSZ CTSZ PARD6G PARD6G RND3 RND3 ADD3 ADD3 EXOC3L1 EXOC3L1 MTSS1L MTSS1L EZR EZR Z169_11677 Z169_11677 Z169_15570 Z169_15570 EXOC1 EXOC1 Z169_15936 Z169_15936 Z169_06119 Z169_06119 HIP1R HIP1R C2CD2L C2CD2L Z169_12842 Z169_12842 PLEKHH2 PLEKHH2 WDR1 WDR1 SEPT8 SEPT8 FRYL FRYL EXOC5 EXOC5 Z169_02283 Z169_02283 Z169_15937 Z169_15937 CTBP2 CTBP2 VCL VCL Z169_07888 Z169_07888 GLRX3 GLRX3 MAPRE1 MAPRE1 ARC ARC SEPT5 SEPT5 Z169_07885 Z169_07885 GNAI3 GNAI3 Z169_13865 Z169_13865 SEPT10 SEPT10 GNAI2 GNAI2 RHOC RHOC Z169_04556 Z169_04556 Z169_05890 Z169_05890 STXBP6 STXBP6 Z169_13866 Z169_13866 Z169_11466 Z169_11466 Z169_13143 Z169_13143 SEPT7 SEPT7 Z169_11115 Z169_11115 ANLN ANLN MPP1 MPP1 Z169_11335 Z169_11335 TNFAIP2 TNFAIP2 BASP1 BASP1 Z169_08256 Z169_08256 SEPT6 SEPT6 PARD3B PARD3B NSMF NSMF Z169_08143 Z169_08143 Z169_11465 Z169_11465 Z169_15200 Z169_15200 ITCH ITCH RHOBTB2 RHOBTB2 EXOC3L4 EXOC3L4 Z169_09934 Z169_09934 Z169_07709 Z169_07709 EXOC2 EXOC2 Z169_09899 Z169_09899 RIMS3 RIMS3 Z169_16370 Z169_16370 CTNNB1 CTNNB1 FAM110C FAM110C RIC8B RIC8B AXIN1 AXIN1 Z169_07708 Z169_07708 RHOF RHOF CTBP1 CTBP1 Z169_13788 Z169_13788 Z169_09330 Z169_09330 ACTN1 ACTN1 EXOC4 EXOC4 SLC2A1 SLC2A1 Z169_05836 Z169_05836 PSEN2 PSEN2 Z169_06881 Z169_06881 SEPT3 SEPT3 Z169_12154 Z169_12154 Z169_00071 Z169_00071 FGF1 FGF1 BSN BSN Z169_11859 Z169_11859 ARF6 ARF6 Z169_05284 Z169_05284 CLTB CLTB CNKSR1 CNKSR1 KDF1 KDF1 MKLN1 MKLN1 Z169_11858 Z169_11858 NDFIP1 NDFIP1 DCTN4 DCTN4 RAC2 RAC2 ACTR2 ACTR2 SHROOM1 SHROOM1 Z169_07240 Z169_07240 CLASP2 CLASP2 RAC3 RAC3 Z169_08342 Z169_08342 Z169_06198 Z169_06198 NOS2 NOS2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PAFAH1B1Lissencephaly-1. (399 aa)
PARD3Partitioning defective 3. (1236 aa)
MYO6Unconventional myosin-VI; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1289 aa)
Z169_14933Uncharacterized protein. (117 aa)
CRIP2Cysteine-rich protein 2. (194 aa)
Z169_00608Merlin. (552 aa)
SEPT4Septin-4; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (302 aa)
UNC13CProtein unc-13 C. (2168 aa)
MYO1BUnconventional myosin-Ib; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1100 aa)
EXOC3Exocyst complex component 3. (746 aa)
NF2Merlin. (439 aa)
PFN4Profilin-4; Belongs to the profilin family. (120 aa)
MELKNon-specific serine/threonine protein kinase. (657 aa)
SEPT11Septin-11; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (424 aa)
RHOHRho-related GTP-binding protein RhoH. (192 aa)
Z169_02852Neurabin-1. (1061 aa)
Z169_04862Exocyst complex component 1. (381 aa)
FNBP1LFormin-binding protein 1-like. (541 aa)
Z169_08280Lethal(2) giant larvae protein 2. (708 aa)
SEPT9Septin-9; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (268 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (545 aa)
Z169_11467Partitioning defective 3 B. (148 aa)
UNC13BProtein unc-13 B. (110 aa)
COTL1Coactosin-like. (116 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (116 aa)
CAPZA2F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (274 aa)
RHOBTB1Rho-related BTB domain-containing protein 1. (689 aa)
STOX1Storkhead-box protein 1. (625 aa)
CAPZBF-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (272 aa)
SPIRE1Protein spire 1. (631 aa)
CDH2Cadherin-2; Cadherins are calcium-dependent cell adhesion proteins. (888 aa)
Z169_13722Rho-related GTP-binding protein RhoG. (191 aa)
MYRIPRab effector MyRIP. (753 aa)
GNAI1Guanine nucleotide-binding protein G(I) subunit alpha-1. (366 aa)
EPB41Protein 4.1. (870 aa)
ECT2Protein ECT2. (908 aa)
NRBP1Nuclear receptor-binding protein. (463 aa)
INSCProtein inscuteable. (522 aa)
Z169_00673Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (404 aa)
DFNB59Pejvakin. (72 aa)
Z169_11631Protein Shroom2. (1449 aa)
Z169_02256Protein piccolo. (3393 aa)
EPB41L2Band 4.1-like 2. (962 aa)
SEPT2Septin-2; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (327 aa)
ARV1Protein ARV1. (201 aa)
Z169_14726Aquaporin-7; Belongs to the MIP/aquaporin (TC 1.A.8) family. (281 aa)
PARD6BPartitioning defective 6 beta. (347 aa)
CIB2Calcium and integrin-binding family member 2. (161 aa)
Z169_06680Protein unc-13 A. (110 aa)
CTSZCathepsin Z; Belongs to the peptidase C1 family. (204 aa)
PARD6GPartitioning defective 6 gamma. (282 aa)
RND3Rho-related GTP-binding protein RhoE. (172 aa)
ADD3Gamma-adducin. (708 aa)
EXOC3L1Exocyst complex component 3-like. (739 aa)
MTSS1LMTSS1-like. (655 aa)
EZREzrin. (582 aa)
Z169_11677Formin-binding protein 1. (545 aa)
Z169_15570C2 domain-containing protein 5. (1024 aa)
EXOC1Exocyst complex component 1. (895 aa)
Z169_15936Ras-like GTP-binding protein Rho1. (193 aa)
Z169_06119Partitioning defective 6 beta. (285 aa)
HIP1RHuntingtin-interacting protein 1-related protein. (907 aa)
C2CD2LC2 domain-containing protein 2-like. (592 aa)
Z169_12842Exocyst complex component 6. (758 aa)
PLEKHH2Pleckstrin homology domain-containing family H member 2. (1500 aa)
WDR1WD repeat-containing protein 1. (593 aa)
SEPT8Septin-8; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (476 aa)
FRYLProtein furry homolog-like. (2991 aa)
EXOC5Exocyst complex component 5. (698 aa)
Z169_02283Hematopoietic lineage cell-specific protein. (485 aa)
Z169_15937Rho-related GTP-binding protein RhoB. (188 aa)
CTBP2C-terminal-binding protein 2; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (417 aa)
VCLVinculin. (1013 aa)
Z169_07888CLIP-associating protein 1. (1473 aa)
GLRX3Glutaredoxin-3. (227 aa)
MAPRE1Microtubule-associated protein RP/EB family member 1. (264 aa)
ARCActivity-regulated cytoskeleton-associated protein. (395 aa)
SEPT5Septin-5; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (291 aa)
Z169_07885Myosin-M heavy chain. (463 aa)
GNAI3Guanine nucleotide-binding protein G(K) subunit alpha. (314 aa)
Z169_13865Cytohesin-interacting protein. (314 aa)
SEPT10Septin-10; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (417 aa)
GNAI2Guanine nucleotide-binding protein G(I) subunit alpha-2. (315 aa)
RHOCRho-related GTP-binding protein RhoC. (193 aa)
Z169_04556Transforming protein RhoA. (213 aa)
Z169_05890Protein cordon-bleu. (411 aa)
STXBP6Syntaxin-binding protein 6. (204 aa)
Z169_13866Ermin. (230 aa)
Z169_11466Partitioning defective 3 B. (98 aa)
Z169_13143Regulating synaptic membrane exocytosis protein 1. (1610 aa)
SEPT7Septin-7; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (286 aa)
Z169_11115Src substrate protein p85. (516 aa)
ANLNActin-binding protein anillin. (1111 aa)
MPP155 kDa erythrocyte membrane protein. (433 aa)
Z169_11335Protein spire 1. (340 aa)
TNFAIP2Tumor necrosis factor alpha-induced protein 2. (438 aa)
BASP1Brain acid soluble protein 1. (244 aa)
Z169_08256Exocyst complex component 7; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. (696 aa)
SEPT6Septin-6; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (417 aa)
PARD3BPartitioning defective 3 B. (281 aa)
NSMFNMDA receptor synaptonuclear signaling and neuronal migration factor. (499 aa)
Z169_08143Uncharacterized protein. (252 aa)
Z169_11465Partitioning defective 3 B. (124 aa)
Z169_15200Rho GTPase-activating protein 32. (1764 aa)
ITCHE3 ubiquitin-protein ligase Itchy. (855 aa)
RHOBTB2Rho-related BTB domain-containing protein 2. (708 aa)
EXOC3L4Exocyst complex component 3-like 4. (533 aa)
Z169_09934Rho-related GTP-binding protein RhoG. (191 aa)
Z169_07709A-kinase anchor protein 13. (1366 aa)
EXOC2Exocyst complex component 2; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family. (926 aa)
Z169_09899Rab effector MyRIP. (72 aa)
RIMS3Regulating synaptic membrane exocytosis protein 3. (311 aa)
Z169_16370Rho GTPase-activating protein 32. (125 aa)
CTNNB1Catenin beta-1. (777 aa)
FAM110CProtein FAM110C. (362 aa)
RIC8BSynembryn-B. (491 aa)
AXIN1Axin-1. (841 aa)
Z169_07708A-kinase anchor protein 13. (260 aa)
RHOFRho-related GTP-binding protein RhoF. (166 aa)
CTBP1C-terminal-binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (428 aa)
Z169_13788Protein unc-13 B. (1454 aa)
Z169_09330Drebrin. (321 aa)
ACTN1Alpha-actinin-1. (852 aa)
EXOC4Exocyst complex component 4. (581 aa)
SLC2A1Solute carrier family 2, facilitated glucose transporter member 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (490 aa)
Z169_05836Exocyst complex component 4. (311 aa)
PSEN2Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (458 aa)
Z169_06881Ras-related C3 botulinum toxin substrate 1. (180 aa)
SEPT3Neuronal-specific septin-3; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (294 aa)
Z169_12154ELKS/Rab6-interacting/CAST family member 1. (861 aa)
Z169_00071Protein Shroom1. (166 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
BSNProtein bassoon. (2269 aa)
Z169_11859Dynactin subunit 1. (116 aa)
ARF6ADP-ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (168 aa)
Z169_05284Macrophage erythroblast attacher. (413 aa)
CLTBClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (164 aa)
CNKSR1Connector enhancer of kinase suppressor of ras 1. (128 aa)
KDF1Uncharacterized protein C1orf172. (362 aa)
MKLN1Muskelin. (702 aa)
Z169_11858Dynactin subunit 1. (110 aa)
NDFIP1NEDD4 family-interacting protein 1. (201 aa)
DCTN4Dynactin subunit 4. (424 aa)
RAC2Ras-related C3 botulinum toxin substrate 2. (195 aa)
ACTR2Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (378 aa)
SHROOM1Protein Shroom1. (358 aa)
Z169_07240Neurabin-1. (1121 aa)
CLASP2CLIP-associating protein 2. (1457 aa)
RAC3Ras-related C3 botulinum toxin substrate 3. (180 aa)
Z169_08342Aspartyl/asparaginyl beta-hydroxylase. (710 aa)
Z169_06198C-terminal-binding protein 2; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (423 aa)
NOS2Nitric oxide synthase, inducible. (1141 aa)
Your Current Organism:
Egretta garzetta
NCBI taxonomy Id: 188379
Other names: E. garzetta, little egret
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