STRINGSTRING
SEMA5B SEMA5B ACTA2 ACTA2 FRZB FRZB BNC2 BNC2 MEOX1 MEOX1 TGFBR3 TGFBR3 GSC GSC Z169_04624 Z169_04624 Z169_04562 Z169_04562 SEMA3G SEMA3G SOX8 SOX8 SNAI2 SNAI2 MDM4 MDM4 EDNRB EDNRB ACVR1 ACVR1 FGF8 FGF8 SEMA3F SEMA3F BMP5 BMP5 PEF1 PEF1 SEMA5A SEMA5A SEMA4G SEMA4G EDN1 EDN1 Z169_11140 Z169_11140 CTNNA3 CTNNA3 DDX5 DDX5 TMEM100 TMEM100 SEMA6B SEMA6B MSX1 MSX1 HTR2B HTR2B EOMES EOMES POGLUT1 POGLUT1 NOG NOG CTNNB1 CTNNB1 TGFBR2 TGFBR2 Z169_15435 Z169_15435 ACVRL1 ACVRL1 SEMA6A SEMA6A Z169_09891 Z169_09891 EXOC4 EXOC4 FAM101B FAM101B Z169_05836 Z169_05836 FAM172A FAM172A PITX2 PITX2 FGF1 FGF1 NELL2 NELL2 KBTBD8 KBTBD8 PTN PTN Z169_03821 Z169_03821 FN1 FN1 SMO SMO CTNNA1 CTNNA1 ANXA6 ANXA6 DDX17 DDX17 SOX10 SOX10 TCOF1 TCOF1 GDNF GDNF Z169_03744 Z169_03744 EDNRA EDNRA PPP3R1 PPP3R1 RET RET POLR1B POLR1B BMP2 BMP2 CER1 CER1 SEMA4D SEMA4D OLFM3 OLFM3 WNT11 WNT11 TGFB3 TGFB3 Z169_08192 Z169_08192 ROCK1 ROCK1 Z169_09711 Z169_09711 LRP6 LRP6 CDH2 CDH2 SEMA3E SEMA3E Z169_03743 Z169_03743 SEMA3C SEMA3C JAG1 JAG1 SEMA3A SEMA3A Z169_11497 Z169_11497 BMP7 BMP7 WWTR1 WWTR1 SEMA3D SEMA3D CDC42 CDC42 SNAI1 SNAI1 SEMA6D SEMA6D KLHL12 KLHL12 CCNB2 CCNB2 Z169_00824 Z169_00824 Z169_15476 Z169_15476 SIX4 SIX4 PDCD6 PDCD6 Z169_09975 Z169_09975 TBX3 TBX3 TCF21 TCF21 Z169_10181 Z169_10181 NUP133 NUP133 FBXL17 FBXL17 OLFM1 OLFM1 Z169_11345 Z169_11345 Z169_12711 Z169_12711 BMPR2 BMPR2 TAPT1 TAPT1 PHOX2B PHOX2B Z169_12754 Z169_12754 Z169_04874 Z169_04874
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SEMA5BSemaphorin-5B. (1093 aa)
ACTA2Actin, aortic smooth muscle. (377 aa)
FRZBSecreted frizzled-related protein 3. (160 aa)
BNC2Zinc finger protein basonuclin-2. (928 aa)
MEOX1Homeobox protein MOX-1. (97 aa)
TGFBR3Transforming growth factor beta receptor type 3. (825 aa)
GSCHomeobox protein goosecoid. (137 aa)
Z169_04624Semaphorin-3D. (638 aa)
Z169_04562Semaphorin-3B. (369 aa)
SEMA3GSemaphorin-3G. (688 aa)
SOX8Transcription factor SOX-8. (324 aa)
SNAI2Zinc finger protein SNAI2. (268 aa)
MDM4Protein Mdm4; Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Belongs to the MDM2/MDM4 family. (474 aa)
EDNRBG_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (354 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (492 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (192 aa)
SEMA3FSemaphorin-3F. (458 aa)
BMP5Bone morphogenetic protein 5. (453 aa)
PEF1Peflin. (178 aa)
SEMA5ASemaphorin-5A. (964 aa)
SEMA4GSemaphorin-4G. (603 aa)
EDN1Endothelin-1. (167 aa)
Z169_11140Protein kinase C-binding protein NELL1. (793 aa)
CTNNA3Catenin alpha-3. (194 aa)
DDX5Putative ATP-dependent RNA helicase DDX5; Belongs to the DEAD box helicase family. (592 aa)
TMEM100Transmembrane protein 100. (134 aa)
SEMA6BSemaphorin-6B. (465 aa)
MSX1Homeobox protein GHOX-7. (152 aa)
HTR2B5-hydroxytryptamine receptor 2B. (430 aa)
EOMESEomesodermin. (391 aa)
POGLUT1Protein O-glucosyltransferase 1. (364 aa)
NOGNoggin. (216 aa)
CTNNB1Catenin beta-1. (777 aa)
TGFBR2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (497 aa)
Z169_15435High mobility group protein HMGI-C. (46 aa)
ACVRL1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (135 aa)
SEMA6ASemaphorin-6A; Belongs to the semaphorin family. (1027 aa)
Z169_09891Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (320 aa)
EXOC4Exocyst complex component 4. (581 aa)
FAM101BProtein FAM101B. (146 aa)
Z169_05836Exocyst complex component 4. (311 aa)
FAM172AProtein FAM172A. (416 aa)
PITX2Pituitary homeobox 2. (188 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
NELL2Protein NEL. (739 aa)
KBTBD8Kelch repeat and BTB domain-containing protein 8. (587 aa)
PTNPleiotrophin. (165 aa)
Z169_03821Endoglin. (570 aa)
FN1Fibronectin. (2431 aa)
SMOG_PROTEIN_RECEP_F2_4 domain-containing protein; Belongs to the G-protein coupled receptor Fz/Smo family. (465 aa)
CTNNA1Catenin alpha-1. (905 aa)
ANXA6Annexin. (660 aa)
DDX17Putative ATP-dependent RNA helicase DDX17; Belongs to the DEAD box helicase family. (476 aa)
SOX10Transcription factor SOX-10. (463 aa)
TCOF1Uncharacterized protein. (522 aa)
GDNFGlial cell line-derived neurotrophic factor. (218 aa)
Z169_03744Protein FAM83D. (200 aa)
EDNRAEndothelin-1 receptor; Belongs to the G-protein coupled receptor 1 family. (421 aa)
PPP3R1Calcineurin subunit B type 1. (156 aa)
RETProto-oncogene tyrosine-protein kinase receptor Ret. (1076 aa)
POLR1BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1020 aa)
BMP2TGF_BETA_2 domain-containing protein. (281 aa)
CER1Cerberus. (273 aa)
SEMA4DSemaphorin-4D. (824 aa)
OLFM3Noelin-3. (478 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (320 aa)
TGFB3Transforming growth factor beta-3. (295 aa)
Z169_08192Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
ROCK1Rho-associated protein kinase 1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1332 aa)
Z169_09711Neurturin. (221 aa)
LRP6Low-density lipoprotein receptor-related protein 6. (1594 aa)
CDH2Cadherin-2; Cadherins are calcium-dependent cell adhesion proteins. (888 aa)
SEMA3ESemaphorin-3E. (737 aa)
Z169_03743Protein FAM83D. (380 aa)
SEMA3CSemaphorin-3C; Belongs to the semaphorin family. (751 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1193 aa)
SEMA3ASemaphorin-3A; Belongs to the semaphorin family. (772 aa)
Z169_11497Band 4.1-like 5. (579 aa)
BMP7Bone morphogenetic protein 7. (292 aa)
WWTR1WW domain-containing transcription regulator protein 1. (271 aa)
SEMA3DSemaphorin-3D. (764 aa)
CDC42Cell division control protein 42. (163 aa)
SNAI1Protein snail Sna. (165 aa)
SEMA6DSemaphorin-6D; Belongs to the semaphorin family. (1068 aa)
KLHL12Kelch-like 12. (511 aa)
CCNB2G2/mitotic-specific cyclin-B2; Belongs to the cyclin family. (392 aa)
Z169_00824T-box transcription factor TBX2-A. (588 aa)
Z169_15476Transcription initiation factor TFIID subunit 10. (134 aa)
SIX4Homeobox protein SIX4. (686 aa)
PDCD6Programmed cell death protein 6. (158 aa)
Z169_09975Lymphoid enhancer-binding factor 1. (315 aa)
TBX3Uncharacterized protein. (179 aa)
TCF21Transcription factor 21. (150 aa)
Z169_10181Muellerian-inhibiting factor. (391 aa)
NUP133Nuclear pore complex protein Nup133. (1095 aa)
FBXL17F-box/LRR-repeat protein 17. (328 aa)
OLFM1Noelin. (430 aa)
Z169_11345Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (96 aa)
Z169_12711Disks large 5. (1827 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1031 aa)
TAPT1Transmembrane anterior posterior transformation protein 1. (501 aa)
PHOX2BPaired mesoderm homeobox protein 2B. (141 aa)
Z169_12754Nucleolar and coiled-body phosphoprotein 1. (607 aa)
Z169_04874G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (432 aa)
Your Current Organism:
Egretta garzetta
NCBI taxonomy Id: 188379
Other names: E. garzetta, little egret
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