STRINGSTRING
PKD1 PKD1 WNT11 WNT11 Z169_11960 Z169_11960 Z169_14388 Z169_14388 TCF21 TCF21 FGF1 FGF1 Z169_13616 Z169_13616 CTNNB1 CTNNB1 GREM1 GREM1 NOG NOG HS2ST1 HS2ST1 BMP4 BMP4 Z169_12332 Z169_12332 GREB1L GREB1L GDNF GDNF Z169_09647 Z169_09647 FGF8 FGF8 Z169_16297 Z169_16297 GREB1 GREB1 Z169_04855 Z169_04855 IRX3 IRX3 SOX8 SOX8 GATA3 GATA3 IRX1 IRX1 TMEM59L TMEM59L
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PKD1Polycystin-1. (4292 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (320 aa)
Z169_11960Uncharacterized protein. (248 aa)
Z169_14388Beta-catenin-interacting protein 1. (72 aa)
TCF21Transcription factor 21. (150 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
Z169_13616Transcription factor HES-5. (157 aa)
CTNNB1Catenin beta-1. (777 aa)
GREM1Gremlin-1. (167 aa)
NOGNoggin. (216 aa)
HS2ST1Heparan sulfate 2-O-sulfotransferase 1. (315 aa)
BMP4Bone morphogenetic protein 4. (350 aa)
Z169_12332COMM domain-containing protein 5. (177 aa)
GREB1LGREB1-like. (1910 aa)
GDNFGlial cell line-derived neurotrophic factor. (218 aa)
Z169_09647Jouberin. (1148 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (192 aa)
Z169_16297Homeobox protein Hox-A11. (248 aa)
GREB1Protein GREB1. (1940 aa)
Z169_04855Homeobox protein Hox-C11a. (280 aa)
IRX3Iroquois-class homeodomain protein irx-3. (67 aa)
SOX8Transcription factor SOX-8. (324 aa)
GATA3GATA-binding factor 3. (351 aa)
IRX1Iroquois-class homeodomain protein irx-1-A. (387 aa)
TMEM59LTransmembrane protein 59-like. (70 aa)
Your Current Organism:
Egretta garzetta
NCBI taxonomy Id: 188379
Other names: E. garzetta, little egret
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