STRINGSTRING
DOCK4 DOCK4 TOMM70A TOMM70A MYBPC3 MYBPC3 Z169_13186 Z169_13186 IGFBP5 IGFBP5 CAV1 CAV1 SMAD7 SMAD7 ROCK1 ROCK1 ERRFI1 ERRFI1 ADRA1A ADRA1A ABCC8 ABCC8 GTF2IRD1 GTF2IRD1 Z169_14294 Z169_14294 CHRM3 CHRM3 JUP JUP TNNT2 TNNT2 P2RX1 P2RX1 ADRA2A ADRA2A ADRA2C ADRA2C Z169_15580 Z169_15580 TRIM63 TRIM63 ATP2A2 ATP2A2 GPER1 GPER1 TACR1 TACR1 P2RX4 P2RX4 Z169_14208 Z169_14208 PDE9A PDE9A GLRX3 GLRX3 TMEM8C TMEM8C MYL3 MYL3 TNNC1 TNNC1 TACR3 TACR3 Z169_04184 Z169_04184 ZDHHC21 ZDHHC21 ANKRD28 ANKRD28 ZC3H12A ZC3H12A ANKRD66 ANKRD66 Z169_00338 Z169_00338 Z169_15780 Z169_15780 GSK3B GSK3B CASQ2 CASQ2 Z169_00395 Z169_00395 TNNT3 TNNT3 EDN1 EDN1 CMYA5 CMYA5 MEF2A MEF2A FBXO32 FBXO32 Z169_02981 Z169_02981 TMEM38B TMEM38B ADORA2B ADORA2B KCNQ1 KCNQ1 CAV3 CAV3 TNNI1 TNNI1 Z169_08090 Z169_08090 IGF1 IGF1 SLC9A1 SLC9A1 CHRM2 CHRM2 MTPN MTPN ANXA6 ANXA6 SRI SRI PKP2 PKP2 PLN PLN
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DOCK4Dedicator of cytokinesis protein 4; Belongs to the DOCK family. (1965 aa)
TOMM70AMitochondrial import receptor subunit TOM70. (501 aa)
MYBPC3Myosin-binding protein C, cardiac-type. (1240 aa)
Z169_13186Myocardin. (950 aa)
IGFBP5Insulin-like growth factor-binding protein 5. (159 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (116 aa)
SMAD7Mothers against decapentaplegic 7. (180 aa)
ROCK1Rho-associated protein kinase 1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1332 aa)
ERRFI1ERBB receptor feedback inhibitor 1. (465 aa)
ADRA1AAlpha-1A adrenergic receptor. (327 aa)
ABCC8ATP-binding cassette sub-family C member 8. (1506 aa)
GTF2IRD1General transcription factor II-I repeat domain-containing protein 1. (957 aa)
Z169_14294PRKC apoptosis WT1 regulator protein. (168 aa)
CHRM3Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (610 aa)
JUPJunction plakoglobin. (521 aa)
TNNT2Troponin T, cardiac muscle isoforms. (213 aa)
P2RX1P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (389 aa)
ADRA2AAlpha-2A adrenergic receptor. (395 aa)
ADRA2CAlpha-2C adrenergic receptor. (413 aa)
Z169_15580Spexin. (110 aa)
TRIM63E3 ubiquitin-protein ligase TRIM63. (341 aa)
ATP2A2Sarcoplasmic/endoplasmic reticulum calcium ATPase 2; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (993 aa)
GPER1G-protein coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (320 aa)
TACR1Substance-P receptor; Belongs to the G-protein coupled receptor 1 family. (385 aa)
P2RX4p2X purinoceptor 4. (335 aa)
Z169_14208RING finger protein 207. (383 aa)
PDE9APhosphodiesterase. (498 aa)
GLRX3Glutaredoxin-3. (227 aa)
TMEM8CProtein myomaker. (220 aa)
MYL3Myosin light chain 1, cardiac muscle. (153 aa)
TNNC1Troponin C, slow skeletal and cardiac muscles. (158 aa)
TACR3Neuromedin-K receptor; Belongs to the G-protein coupled receptor 1 family. (422 aa)
Z169_04184Protein-histidine N-methyltransferase. (371 aa)
ZDHHC21Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (265 aa)
ANKRD28Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A. (1086 aa)
ZC3H12ARibonuclease ZC3H12A. (481 aa)
ANKRD66Ankyrin repeat domain-containing protein 66. (182 aa)
Z169_00338Peptidase inhibitor 16. (268 aa)
Z169_15780Tumor necrosis factor receptor superfamily member 1A. (417 aa)
GSK3BGlycogen synthase kinase-3 beta; Belongs to the protein kinase superfamily. (371 aa)
CASQ2Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (404 aa)
Z169_00395Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1221 aa)
TNNT3Troponin T, fast skeletal muscle isoforms. (204 aa)
EDN1Endothelin-1. (167 aa)
CMYA5Cardiomyopathy-associated protein 5. (88 aa)
MEF2AMyocyte-specific enhancer factor 2A. (494 aa)
FBXO32F-box only protein 32. (312 aa)
Z169_02981Serine/threonine-protein kinase TNNI3K. (880 aa)
TMEM38BTrimeric intracellular cation channel type B. (252 aa)
ADORA2BAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (340 aa)
KCNQ1Potassium voltage-gated channel subfamily KQT member 1; Belongs to the potassium channel family. (376 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (97 aa)
TNNI1Troponin I, slow skeletal muscle. (182 aa)
Z169_08090LIM and cysteine-rich domains protein 1. (317 aa)
IGF1Insulin-like growth factor I. (114 aa)
SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (478 aa)
CHRM2Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (466 aa)
MTPNMyotrophin. (98 aa)
ANXA6Annexin. (660 aa)
SRISorcin. (181 aa)
PKP2Plakophilin-2. (766 aa)
PLNCardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. (52 aa)
Your Current Organism:
Egretta garzetta
NCBI taxonomy Id: 188379
Other names: E. garzetta, little egret
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