STRINGSTRING
Z169_08354 Z169_08354 Z169_16360 Z169_16360 SRD5A2 SRD5A2 Z169_12098 Z169_12098 SRD5A1 SRD5A1 Z169_05365 Z169_05365 STS STS Z169_05364 Z169_05364 SRD5A3 SRD5A3 Z169_06529 Z169_06529 HSD11B2 HSD11B2 DHRS11 DHRS11 Z169_01580 Z169_01580 Z169_06699 Z169_06699 Z169_14965 Z169_14965 Z169_07126 Z169_07126 Z169_07127 Z169_07127 Z169_01727 Z169_01727 COMT COMT HSD17B7 HSD17B7 HSD17B2 HSD17B2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Z169_08354Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. (513 aa)
Z169_16360Sulfotransferase; Belongs to the sulfotransferase 1 family. (292 aa)
SRD5A23-oxo-5-alpha-steroid 4-dehydrogenase 2. (168 aa)
Z169_12098Cytochrome P450 2D17; Belongs to the cytochrome P450 family. (450 aa)
SRD5A13-oxo-5-alpha-steroid 4-dehydrogenase 1. (146 aa)
Z169_05365Corticosteroid 11-beta-dehydrogenase isozyme 1. (220 aa)
STSSteryl-sulfatase. (554 aa)
Z169_05364Corticosteroid 11-beta-dehydrogenase isozyme 1. (292 aa)
SRD5A3Polyprenol reductase. (242 aa)
Z169_06529Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] (66 aa)
HSD11B2Corticosteroid 11-beta-dehydrogenase isozyme 2. (300 aa)
DHRS11Dehydrogenase/reductase SDR family member 11; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (211 aa)
Z169_0158025-hydroxycholesterol 7-alpha-hydroxylase. (473 aa)
Z169_06699Cytochrome P450 19A1; Belongs to the cytochrome P450 family. (498 aa)
Z169_14965UDP-glucuronosyltransferase 1-3. (137 aa)
Z169_07126Cytochrome P450 3A24; Belongs to the cytochrome P450 family. (493 aa)
Z169_07127Cytochrome P450 3A9; Belongs to the cytochrome P450 family. (485 aa)
Z169_01727Steroid 17-alpha-hydroxylase/17,20 lyase; Belongs to the cytochrome P450 family. (507 aa)
COMTCatechol O-methyltransferase. (232 aa)
HSD17B73-keto-steroid reductase. (305 aa)
HSD17B2Estradiol 17-beta-dehydrogenase 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (283 aa)
Your Current Organism:
Egretta garzetta
NCBI taxonomy Id: 188379
Other names: E. garzetta, little egret
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