STRINGSTRING
Z169_11634 Z169_11634 ADRBK2 ADRBK2 RAB10 RAB10 PRKCZ PRKCZ GIT2 GIT2 IST1 IST1 AP2A2 AP2A2 CHMP6 CHMP6 CLTB CLTB ARF6 ARF6 IL2RB IL2RB MVB12B MVB12B CYTH4 CYTH4 EHD3 EHD3 EPN2 EPN2 PSD2 PSD2 CYTH3 CYTH3 Z169_14095 Z169_14095 Z169_05303 Z169_05303 IGF1R IGF1R CCDC53 CCDC53 STAM STAM TGFBR2 TGFBR2 Z169_00807 Z169_00807 CHMP1B CHMP1B CAV3 CAV3 VPS29 VPS29 CLTC CLTC TSG101 TSG101 SMAP2 SMAP2 VPS4B VPS4B AGAP1 AGAP1 Z169_01439 Z169_01439 Z169_03420 Z169_03420 AP2M1 AP2M1 ARFGEF1 ARFGEF1 CHMP1A CHMP1A SMURF2 SMURF2 DNAJC6 DNAJC6 SPG21 SPG21 IL2RG IL2RG IQSEC1 IQSEC1 CHMP2B CHMP2B RAB5C RAB5C TFRC TFRC WWP1 WWP1 SNX12 SNX12 EPS15L1 EPS15L1 ITCH ITCH RAB11FIP4 RAB11FIP4 PIP5K1B PIP5K1B SNX2 SNX2 RAB8A RAB8A SH3GL1 SH3GL1 WASL WASL IGF2R IGF2R PIP5K1C PIP5K1C SMAD3 SMAD3 EPN3 EPN3 RAB7A RAB7A ACAP2 ACAP2 Z169_02187 Z169_02187 RAB11FIP1 RAB11FIP1 ARF4 ARF4 ARPC2 ARPC2 ZFYVE16 ZFYVE16 ASAP2 ASAP2 GRK7 GRK7 RAB11FIP2 RAB11FIP2 GRK5 GRK5 SH3GL2 SH3GL2 VPS25 VPS25 FGFR4 FGFR4 Z169_16445 Z169_16445 EHD4 EHD4 CHMP5 CHMP5 SNX4 SNX4 VPS37A VPS37A FAM21C FAM21C VPS36 VPS36 HSPA8 HSPA8 ARPC5 ARPC5 IQSEC3 IQSEC3 VPS45 VPS45 CXCR4 CXCR4 KIAA0196 KIAA0196 PSD PSD Z169_11359 Z169_11359 GBF1 GBF1 Z169_05851 Z169_05851 Z169_06119 Z169_06119 Z169_15936 Z169_15936 WASH1 WASH1 SNX1 SNX1 VTA1 VTA1 RAB35 RAB35 ARPC3 ARPC3 VPS37B VPS37B FGFR3 FGFR3 STAMBP STAMBP GRK4 GRK4 HSPA2 HSPA2 PARD6G PARD6G GRK6 GRK6 EPS15 EPS15 ZFYVE20 ZFYVE20 ARFGAP1 ARFGAP1 USP8 USP8 RAB22A RAB22A PARD6B PARD6B SH3GL3 SH3GL3 CDC42 CDC42 RAB4A RAB4A ASAP3 ASAP3 ARPC1A ARPC1A ZFYVE9 ZFYVE9 STAM2 STAM2 Z169_08435 Z169_08435 PLD1 PLD1 SNX3 SNX3 SH3GLB1 SH3GLB1 RABEP1 RABEP1 PSD3 PSD3 DNM3 DNM3 CHMP7 CHMP7 KIF5B KIF5B HRAS HRAS RAB11A RAB11A FGFR2 FGFR2 KIAA1033 KIAA1033 MDM2 MDM2 CAPZB CAPZB VPS26A VPS26A CAPZA2 CAPZA2 CAV1 CAV1 Z169_01281 Z169_01281 NEDD4L NEDD4L TRAF6 TRAF6 ARFGAP2 ARFGAP2 VPS35 VPS35 CBL CBL RAB5A RAB5A RAB11B RAB11B RAB11FIP5 RAB11FIP5 CAPZA1 CAPZA1 Z169_16446 Z169_16446 SNX5 SNX5 VPS26B VPS26B KIF5C KIF5C SNF8 SNF8 ARFGEF2 ARFGEF2 PRKCI PRKCI RAB31 RAB31 CAV2 CAV2 PARD3 PARD3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Z169_11634Ras-related protein Rab-11A. (203 aa)
ADRBK2G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (651 aa)
RAB10Ras-related protein Rab-10. (159 aa)
PRKCZProtein kinase C zeta type; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (577 aa)
GIT2ARF GTPase-activating protein GIT2. (743 aa)
IST1IST1. (365 aa)
AP2A2AP-2 complex subunit alpha-2. (928 aa)
CHMP6Charged multivesicular body protein 6. (142 aa)
CLTBClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (164 aa)
ARF6ADP-ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (168 aa)
IL2RBInterleukin-2 receptor subunit beta. (144 aa)
MVB12BMultivesicular body subunit 12B. (226 aa)
CYTH4Cytohesin-4. (364 aa)
EHD3EH domain-containing protein 3; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (535 aa)
EPN2Epsin-2. (529 aa)
PSD2PH and SEC7 domain-containing protein 2. (643 aa)
CYTH3Cytohesin-3. (388 aa)
Z169_14095Folate receptor alpha. (267 aa)
Z169_05303Charged multivesicular body protein 3. (203 aa)
IGF1RTyrosine-protein kinase receptor. (1153 aa)
CCDC53WASH complex subunit CCDC53. (187 aa)
STAMSignal transducing adapter molecule 1. (542 aa)
TGFBR2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (497 aa)
Z169_00807Ras-related protein Rab-5B. (133 aa)
CHMP1BCharged multivesicular body protein 1b. (180 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (97 aa)
VPS29Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. (181 aa)
CLTCClathrin heavy chain 1. (1662 aa)
TSG101Tumor susceptibility 101. (378 aa)
SMAP2Stromal membrane-associated protein 2. (380 aa)
VPS4BVacuolar protein sorting-associated protein 4B; Belongs to the AAA ATPase family. (180 aa)
AGAP1Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1. (797 aa)
Z169_01439E3 ubiquitin-protein ligase NRDP1. (172 aa)
Z169_03420Vacuolar protein sorting-associated protein 37C. (223 aa)
AP2M1AP-2 complex subunit mu; Belongs to the adaptor complexes medium subunit family. (433 aa)
ARFGEF1Brefeldin A-inhibited guanine nucleotide-exchange protein 1. (1804 aa)
CHMP1ACharged multivesicular body protein 1a. (171 aa)
SMURF2E3 ubiquitin-protein ligase SMURF2. (742 aa)
DNAJC6Putative tyrosine-protein phosphatase auxilin. (928 aa)
SPG21Maspardin. (290 aa)
IL2RGCytokine receptor common subunit gamma. (348 aa)
IQSEC1IQ motif and SEC7 domain-containing protein 1. (915 aa)
CHMP2BCharged multivesicular body protein 2b. (203 aa)
RAB5CRas-related protein Rab-5C. (216 aa)
TFRCTransferrin receptor protein 1. (777 aa)
WWP1NEDD4-like E3 ubiquitin-protein ligase WWP1. (906 aa)
SNX12Sorting nexin-12. (109 aa)
EPS15L1Epidermal growth factor receptor substrate 15-like 1. (906 aa)
ITCHE3 ubiquitin-protein ligase Itchy. (855 aa)
RAB11FIP4Rab11 family-interacting protein 4. (580 aa)
PIP5K1BPhosphatidylinositol 4-phosphate 5-kinase type-1 beta. (521 aa)
SNX2Sorting nexin-2. (482 aa)
RAB8ARas-related protein Rab-8A. (171 aa)
SH3GL1Endophilin-A2. (271 aa)
WASLNeural Wiskott-Aldrich syndrome protein. (466 aa)
IGF2RCation-independent mannose-6-phosphate receptor. (2435 aa)
PIP5K1CPhosphatidylinositol 4-phosphate 5-kinase type-1 gamma. (469 aa)
SMAD3Mothers against decapentaplegic 3. (53 aa)
EPN3Epsin-3. (537 aa)
RAB7ARas-related protein Rab-7a. (207 aa)
ACAP2Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2. (762 aa)
Z169_02187Riboflavin-binding protein. (240 aa)
RAB11FIP1Rab11 family-interacting protein 1. (514 aa)
ARF4ADP-ribosylation factor 4; Belongs to the small GTPase superfamily. Arf family. (163 aa)
ARPC2Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (253 aa)
ZFYVE16Zinc finger FYVE domain-containing protein 16. (1216 aa)
ASAP2Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2. (963 aa)
GRK7G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (551 aa)
RAB11FIP2Rab11 family-interacting protein 2. (510 aa)
GRK5G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (572 aa)
SH3GL2Endophilin-A1. (338 aa)
VPS25Vacuolar protein-sorting-associated protein 25. (92 aa)
FGFR4Fibroblast growth factor receptor 4. (742 aa)
Z169_16445C-C chemokine receptor type 5; Belongs to the G-protein coupled receptor 1 family. (350 aa)
EHD4EH domain-containing protein 4; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (466 aa)
CHMP5Charged multivesicular body protein 5. (181 aa)
SNX4Sorting nexin-4. (402 aa)
VPS37AVacuolar protein sorting-associated protein 37A. (353 aa)
FAM21CWASH complex subunit FAM21A. (1288 aa)
VPS36Vacuolar protein-sorting-associated protein 36. (354 aa)
HSPA8Heat shock cognate 71 kDa protein; Belongs to the heat shock protein 70 family. (647 aa)
ARPC5Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (104 aa)
IQSEC3IQ motif and SEC7 domain-containing protein 3. (950 aa)
VPS45Vacuolar protein sorting-associated protein 45; Belongs to the STXBP/unc-18/SEC1 family. (466 aa)
CXCR4C-X-C chemokine receptor type 4; Belongs to the G-protein coupled receptor 1 family. (353 aa)
KIAA0196WASH complex subunit strumpellin. (1151 aa)
PSDPH and SEC7 domain-containing protein 1. (735 aa)
Z169_11359Clathrin heavy chain 1. (1636 aa)
GBF1Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1. (1813 aa)
Z169_05851Sushi domain-containing protein. (68 aa)
Z169_06119Partitioning defective 6 beta. (285 aa)
Z169_15936Ras-like GTP-binding protein Rho1. (193 aa)
WASH1WAS protein family 1. (474 aa)
SNX1Sorting nexin-1. (391 aa)
VTA1Vacuolar protein sorting-associated protein VTA1. (268 aa)
RAB35Ras-related protein Rab-35. (192 aa)
ARPC3Actin-related protein 2/3 complex subunit 3. (178 aa)
VPS37BVacuolar protein sorting-associated protein 37B. (257 aa)
FGFR3Fibroblast growth factor receptor 3. (751 aa)
STAMBPSTAM-binding protein. (431 aa)
GRK4G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (531 aa)
HSPA2Heat shock 70 kDa protein; Belongs to the heat shock protein 70 family. (634 aa)
PARD6GPartitioning defective 6 gamma. (282 aa)
GRK6G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (534 aa)
EPS15Epidermal growth factor receptor substrate 15. (898 aa)
ZFYVE20Rabenosyn-5. (769 aa)
ARFGAP1ADP-ribosylation factor GTPase-activating protein 1. (407 aa)
USP8Ubiquitin carboxyl-terminal hydrolase 8; Belongs to the peptidase C19 family. (1096 aa)
RAB22ARas-related protein Rab-22A. (182 aa)
PARD6BPartitioning defective 6 beta. (347 aa)
SH3GL3Endophilin-A3. (338 aa)
CDC42Cell division control protein 42. (163 aa)
RAB4ARas-related protein Rab-4A. (172 aa)
ASAP3Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3. (635 aa)
ARPC1AActin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (370 aa)
ZFYVE9Zinc finger FYVE domain-containing protein. (1416 aa)
STAM2Signal transducing adapter molecule 2. (513 aa)
Z169_08435Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. (179 aa)
PLD1Phospholipase. (1083 aa)
SNX3Sorting nexin-3. (109 aa)
SH3GLB1Endophilin-B1. (342 aa)
RABEP1Rab GTPase-binding effector protein 1. (806 aa)
PSD3PH and SEC7 domain-containing protein 3. (624 aa)
DNM3Dynamin-3; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (788 aa)
CHMP7Charged multivesicular body protein 7. (346 aa)
KIF5BKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (923 aa)
HRASGTPase HRas. (189 aa)
RAB11ARas-related protein Rab-11A. (203 aa)
FGFR2Fibroblast growth factor receptor. (839 aa)
KIAA1033WASH complex subunit 7. (784 aa)
MDM2E3 ubiquitin-protein ligase Mdm2. (485 aa)
CAPZBF-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (272 aa)
VPS26AVacuolar protein sorting-associated protein 26A. (325 aa)
CAPZA2F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (274 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (116 aa)
Z169_01281Low density lipoprotein receptor adapter protein 1. (150 aa)
NEDD4LE3 ubiquitin-protein ligase NEDD4-like. (942 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (545 aa)
ARFGAP2ADP-ribosylation factor GTPase-activating protein 2. (451 aa)
VPS35Vacuolar protein sorting-associated protein 35. (796 aa)
CBLE3 ubiquitin-protein ligase CBL. (853 aa)
RAB5ARas-related protein Rab-5A. (215 aa)
RAB11BRas-related protein Rab-11B. (205 aa)
RAB11FIP5Rab11 family-interacting protein 5. (525 aa)
CAPZA1F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (273 aa)
Z169_16446C-C chemokine receptor type 2; Belongs to the G-protein coupled receptor 1 family. (350 aa)
SNX5Sorting nexin-5. (387 aa)
VPS26BVacuolar protein sorting-associated protein 26B. (292 aa)
KIF5CKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (915 aa)
SNF8Vacuolar-sorting protein SNF8. (243 aa)
ARFGEF2Brefeldin A-inhibited guanine nucleotide-exchange protein 2. (1746 aa)
PRKCIProtein kinase C iota type; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (562 aa)
RAB31Ras-related protein Rab-31. (182 aa)
CAV2Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (113 aa)
PARD3Partitioning defective 3. (1236 aa)
Your Current Organism:
Egretta garzetta
NCBI taxonomy Id: 188379
Other names: E. garzetta, little egret
Server load: low (16%) [HD]