STRINGSTRING
SQSTM1 SQSTM1 RAD50 RAD50 RASSF5 RASSF5 MAPKAPK2 MAPKAPK2 FBXW11 FBXW11 SLC25A6 SLC25A6 LIN9 LIN9 CCNA1 CCNA1 PIK3CB PIK3CB PPP1CB PPP1CB RBBP4 RBBP4 VDAC3 VDAC3 CALM1 CALM1 TGFBR2 TGFBR2 CDC25A CDC25A PPP3CA PPP3CA CHEK2 CHEK2 PPP1CC PPP1CC Z169_06969 Z169_06969 RRAS2 RRAS2 CCND2 CCND2 RAF1 RAF1 MAP2K2 MAP2K2 CCND1 CCND1 PIK3R1 PIK3R1 E2F1 E2F1 CCNE1 CCNE1 Z169_06970 Z169_06970 MAPK12 MAPK12 NFATC1 NFATC1 SIRT1 SIRT1 MAPK13 MAPK13 NBN NBN PIK3R3 PIK3R3 RBL2 RBL2 NFATC3 NFATC3 PTEN PTEN SMAD3 SMAD3 IL6 IL6 BTRC BTRC AKT1 AKT1 MAPK11 MAPK11 MAPK14 MAPK14 CCNE2 CCNE2 IGFBP3 IGFBP3 CXCL8 CXCL8 CACNA1D CACNA1D CXCL8-2 CXCL8-2 EIF4EBP1 EIF4EBP1 PPP3CC PPP3CC FOXM1 FOXM1 CXCL8-4 CXCL8-4 TSC2 TSC2 ETS1 ETS1 CDK6 CDK6 PPP3CB PPP3CB PIK3CA PIK3CA FOXO1 FOXO1 VDAC2 VDAC2 E2F4 E2F4 RHEB RHEB RB1 RB1 MRE11A MRE11A CCNB2 CCNB2 NFATC2 NFATC2 CDKN1A CDKN1A MYBL2 MYBL2 AKT3 AKT3 MTOR MTOR MAP2K6 MAP2K6 HRAS HRAS MAP2K3 MAP2K3 HIPK3 HIPK3 CAPN11 CAPN11 MDM2 MDM2 SLC25A5 SLC25A5 PPID PPID PIK3CD PIK3CD TGFB3 TGFB3 VDAC1 VDAC1 MAP2K1 MAP2K1 RAD1 RAD1 CCND3 CCND3 HUS1 HUS1 NRAS NRAS HIPK1 HIPK1 ATR ATR PPP3R1 PPP3R1 CCNA2 CCNA2 SLC25A4 SLC25A4 MRAS MRAS TRAF3IP2 TRAF3IP2 CCNB3 CCNB3 LIN52 LIN52 LIN54 LIN54
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SQSTM1Sequestosome-1. (398 aa)
RAD50DNA repair protein RAD50. (1312 aa)
RASSF5Ras association domain-containing protein 5. (258 aa)
MAPKAPK2MAP kinase-activated protein kinase 2. (261 aa)
FBXW11F-box/WD repeat-containing protein 11. (552 aa)
SLC25A6ADP/ATP translocase 3; Belongs to the mitochondrial carrier (TC 2.A.29) family. (261 aa)
LIN9Protein lin-9. (532 aa)
CCNA1Cyclin-A1; Belongs to the cyclin family. (363 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform; Belongs to the PI3/PI4-kinase family. (1069 aa)
PPP1CBSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (312 aa)
RBBP4Histone-binding protein RBBP4. (420 aa)
VDAC3Voltage-dependent anion-selective channel protein 3. (261 aa)
CALM1Calmodulin; Belongs to the calmodulin family. (148 aa)
TGFBR2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (497 aa)
CDC25AM-phase inducer phosphatase 1. (473 aa)
PPP3CASerine/threonine-protein phosphatase. (436 aa)
CHEK2Serine/threonine-protein kinase Chk2. (464 aa)
PPP1CCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (305 aa)
Z169_06969Cyclin-dependent kinase inhibitor 1. (54 aa)
RRAS2Ras-related protein R-Ras2. (171 aa)
CCND2G1/S-specific cyclin-D2; Belongs to the cyclin family. (286 aa)
RAF1RAF proto-oncogene serine/threonine-protein kinase. (647 aa)
MAP2K2Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (367 aa)
CCND1G1/S-specific cyclin-D1; Belongs to the cyclin family. (292 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha. (613 aa)
E2F1Transcription factor E2F1. (188 aa)
CCNE1G1/S-specific cyclin-E1; Belongs to the cyclin family. (367 aa)
Z169_06970Cyclin-dependent kinase inhibitor 1. (54 aa)
MAPK12Mitogen-activated protein kinase. (312 aa)
NFATC1Nuclear factor of activated T-cells, cytoplasmic 1. (882 aa)
SIRT1NAD-dependent protein deacetylase sirtuin-1. (601 aa)
MAPK13Mitogen-activated protein kinase. (299 aa)
NBNNibrin. (753 aa)
PIK3R3Phosphatidylinositol 3-kinase regulatory subunit alpha. (706 aa)
RBL2Retinoblastoma-like 2. (1066 aa)
NFATC3Nuclear factor of activated T-cells, cytoplasmic 3. (1057 aa)
PTENannotation not available (376 aa)
SMAD3Mothers against decapentaplegic 3. (53 aa)
IL6Interleukin-6. (113 aa)
BTRCF-box/WD repeat-containing protein 1A. (593 aa)
AKT1RAC-alpha serine/threonine-protein kinase; Belongs to the protein kinase superfamily. (465 aa)
MAPK11Mitogen-activated protein kinase. (323 aa)
MAPK14Mitogen-activated protein kinase. (320 aa)
CCNE2G1/S-specific cyclin-E2; Belongs to the cyclin family. (400 aa)
IGFBP3Insulin-like growth factor-binding protein 3. (157 aa)
CXCL8Interleukin-8; Belongs to the intercrine alpha (chemokine CxC) family. (95 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2172 aa)
CXCL8-2Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (94 aa)
EIF4EBP1Eukaryotic translation initiation factor 4E-binding protein 1. (67 aa)
PPP3CCSerine/threonine-protein phosphatase. (421 aa)
FOXM1Forkhead box protein M1. (790 aa)
CXCL8-4Interleukin-8; Belongs to the intercrine alpha (chemokine CxC) family. (91 aa)
TSC2Tuberin. (1844 aa)
ETS1Transforming protein p68/c-ets-1. (484 aa)
CDK6Cyclin-dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa)
PPP3CBSerine/threonine-protein phosphatase. (427 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1048 aa)
FOXO1Forkhead box protein O1. (449 aa)
VDAC2Voltage-dependent anion-selective channel protein 2. (284 aa)
E2F4Transcription factor E2F4. (349 aa)
RHEBGTP-binding protein Rheb. (167 aa)
RB1Retinoblastoma-associated protein. (870 aa)
MRE11ADouble-strand break repair protein MRE11; Belongs to the MRE11/RAD32 family. (700 aa)
CCNB2G2/mitotic-specific cyclin-B2; Belongs to the cyclin family. (392 aa)
NFATC2Nuclear factor of activated T-cells, cytoplasmic 2. (882 aa)
CDKN1ACyclin-dependent kinase inhibitor 1. (54 aa)
MYBL2Myb-related protein B. (677 aa)
AKT3RAC-gamma serine/threonine-protein kinase; Belongs to the protein kinase superfamily. (464 aa)
MTORSerine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2519 aa)
MAP2K6Dual specificity mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (271 aa)
HRASGTPase HRas. (189 aa)
MAP2K3Dual specificity mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (329 aa)
HIPK3Homeodomain-interacting protein kinase 3. (1206 aa)
CAPN11Calpain-1 catalytic subunit; Belongs to the peptidase C2 family. (692 aa)
MDM2E3 ubiquitin-protein ligase Mdm2. (485 aa)
SLC25A5ADP/ATP translocase 2; Belongs to the mitochondrial carrier (TC 2.A.29) family. (262 aa)
PPIDPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (137 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform; Belongs to the PI3/PI4-kinase family. (1042 aa)
TGFB3Transforming growth factor beta-3. (295 aa)
VDAC1Voltage-dependent anion-selective channel protein 1. (285 aa)
MAP2K1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (368 aa)
RAD1Cell cycle checkpoint protein RAD1. (219 aa)
CCND3G1/S-specific cyclin-D3; Belongs to the cyclin family. (239 aa)
HUS1Checkpoint protein; Belongs to the HUS1 family. (284 aa)
NRASGTPase NRas. (153 aa)
HIPK1Homeodomain-interacting protein kinase 1. (1163 aa)
ATRSerine/threonine-protein kinase ATR; Belongs to the PI3/PI4-kinase family. (2676 aa)
PPP3R1Calcineurin subunit B type 1. (156 aa)
CCNA2Cyclin-A2; Belongs to the cyclin family. (323 aa)
SLC25A4ADP/ATP translocase 1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (263 aa)
MRASRas-related protein M-Ras. (208 aa)
TRAF3IP2Adapter protein CIKS. (416 aa)
CCNB3G2/mitotic-specific cyclin-B3. (187 aa)
LIN52Protein lin-52. (63 aa)
LIN54Protein lin-54. (752 aa)
Your Current Organism:
Egretta garzetta
NCBI taxonomy Id: 188379
Other names: E. garzetta, little egret
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