STRINGSTRING
PPP2R3B PPP2R3B CREB3L2 CREB3L2 ATF4 ATF4 ADCY8 ADCY8 CACNA2D4 CACNA2D4 SLC9A1 SLC9A1 PPP2R2B PPP2R2B PPP1CB PPP1CB CACNG3 CACNG3 SLC8A3 SLC8A3 CACNB2 CACNB2 CALM1 CALM1 KCNQ1 KCNQ1 ADCY9 ADCY9 PRKACB PRKACB Z169_03855 Z169_03855 PPP1CC PPP1CC PPP2R2C PPP2R2C PPP2R2A PPP2R2A TPM4 TPM4 MAPK12 MAPK12 ATP2B2 ATP2B2 GNAQ GNAQ MAPK13 MAPK13 PPP2R2D PPP2R2D ADCY2 ADCY2 AKT1 AKT1 ATP1A1 ATP1A1 MAPK11 MAPK11 MAPK14 MAPK14 GNAI2 GNAI2 CACNA2D2 CACNA2D2 ADCY1 ADCY1 ATP1B3 ATP1B3 ACTC1 ACTC1 CACNA1D CACNA1D TNNC1 TNNC1 GNAI3 GNAI3 AGTR1 AGTR1 RAPGEF4 RAPGEF4 ADCY5 ADCY5 KCNE1 KCNE1 MYL3 MYL3 ATF2 ATF2 CACNG1 CACNG1 CACNG5 CACNG5 PPP2R5D PPP2R5D ATP2B1 ATP2B1 ATP2A2 ATP2A2 RPS6KA5 RPS6KA5 PPP2R3A PPP2R3A PPP2CB PPP2CB AGT AGT GNAS GNAS TNNT2 TNNT2 Z169_01052 Z169_01052 PLCB2 PLCB2 MYL2 MYL2 AKT3 AKT3 ATP2A3 ATP2A3 TPM3 TPM3 PLCB1 PLCB1 CACNA2D1 CACNA2D1 ADRA1A ADRA1A GNAI1 GNAI1 PIK3CG PIK3CG PPP2R5A PPP2R5A ADRA1B ADRA1B PLCB4 PLCB4 PIK3R5 PIK3R5 PPP2CA PPP2CA PPP2R5C PPP2R5C ADRA1D ADRA1D CREB1 CREB1 TPM2 TPM2 PPP2R5E PPP2R5E CREB5 CREB5 CACNA2D3 CACNA2D3 MYL4 MYL4 PRKCA PRKCA TPM1 TPM1 PLN PLN PPP2R3C PPP2R3C CREB3L1 CREB3L1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PPP2R3BSerine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta. (581 aa)
CREB3L2Cyclic AMP-responsive element-binding protein 3-like 2. (485 aa)
ATF4Cyclic AMP-dependent transcription factor ATF-4. (354 aa)
ADCY8Adenylate cyclase type 8; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (946 aa)
CACNA2D4Voltage-dependent calcium channel subunit alpha-2/delta-4. (1047 aa)
SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (478 aa)
PPP2R2BSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (413 aa)
PPP1CBSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (312 aa)
CACNG3Voltage-dependent calcium channel gamma-3 subunit. (249 aa)
SLC8A3Sodium/calcium exchanger 3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (915 aa)
CACNB2Voltage-dependent L-type calcium channel subunit beta-2. (610 aa)
CALM1Calmodulin; Belongs to the calmodulin family. (148 aa)
KCNQ1Potassium voltage-gated channel subfamily KQT member 1; Belongs to the potassium channel family. (376 aa)
ADCY9Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (818 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
Z169_03855Myosin-6; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1859 aa)
PPP1CCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (305 aa)
PPP2R2CSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (424 aa)
PPP2R2ASerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (423 aa)
TPM4Tropomyosin alpha-1 chain; Belongs to the tropomyosin family. (284 aa)
MAPK12Mitogen-activated protein kinase. (312 aa)
ATP2B2Plasma membrane calcium-transporting ATPase 2; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (1205 aa)
GNAQGuanine nucleotide-binding protein G(Q) subunit alpha. (314 aa)
MAPK13Mitogen-activated protein kinase. (299 aa)
PPP2R2DSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (420 aa)
ADCY2Adenylate cyclase type 2. (1026 aa)
AKT1RAC-alpha serine/threonine-protein kinase; Belongs to the protein kinase superfamily. (465 aa)
ATP1A1Sodium/potassium-transporting ATPase subunit alpha. (1018 aa)
MAPK11Mitogen-activated protein kinase. (323 aa)
MAPK14Mitogen-activated protein kinase. (320 aa)
GNAI2Guanine nucleotide-binding protein G(I) subunit alpha-2. (315 aa)
CACNA2D2Voltage-dependent calcium channel subunit alpha-2/delta-2. (147 aa)
ADCY1Adenylate cyclase type 1. (1090 aa)
ATP1B3Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (246 aa)
ACTC1Actin, alpha cardiac muscle 1; Belongs to the actin family. (334 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2172 aa)
TNNC1Troponin C, slow skeletal and cardiac muscles. (158 aa)
GNAI3Guanine nucleotide-binding protein G(K) subunit alpha. (314 aa)
AGTR1Type-1 angiotensin II receptor; Belongs to the G-protein coupled receptor 1 family. (357 aa)
RAPGEF4Rap guanine nucleotide exchange factor 4. (987 aa)
ADCY5Adenylate cyclase type 5; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (887 aa)
KCNE1Potassium voltage-gated channel subfamily E member 1. (125 aa)
MYL3Myosin light chain 1, cardiac muscle. (153 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2. (493 aa)
CACNG1Voltage-dependent calcium channel gamma-1 subunit; Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics. (236 aa)
CACNG5Voltage-dependent calcium channel gamma-5 subunit. (275 aa)
PPP2R5DSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform. (583 aa)
ATP2B1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1258 aa)
ATP2A2Sarcoplasmic/endoplasmic reticulum calcium ATPase 2; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (993 aa)
RPS6KA5Ribosomal protein S6 kinase alpha-5. (766 aa)
PPP2R3ASerine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha. (1098 aa)
PPP2CBSerine/threonine-protein phosphatase. (275 aa)
AGTAngiotensinogen; Belongs to the serpin family. (461 aa)
GNASGuanine nucleotide-binding protein G(S) subunit alpha. (334 aa)
TNNT2Troponin T, cardiac muscle isoforms. (213 aa)
Z169_01052Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1990 aa)
PLCB2Phosphoinositide phospholipase C. (777 aa)
MYL2Myosin regulatory light chain 2A, cardiac muscle isoform. (165 aa)
AKT3RAC-gamma serine/threonine-protein kinase; Belongs to the protein kinase superfamily. (464 aa)
ATP2A3Sarcoplasmic/endoplasmic reticulum calcium ATPase 3; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (947 aa)
TPM3Tropomyosin alpha-3 chain; Belongs to the tropomyosin family. (284 aa)
PLCB1Phosphoinositide phospholipase C. (1064 aa)
CACNA2D1Voltage-dependent calcium channel subunit alpha-2/delta-1. (1009 aa)
ADRA1AAlpha-1A adrenergic receptor. (327 aa)
GNAI1Guanine nucleotide-binding protein G(I) subunit alpha-1. (366 aa)
PIK3CGPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform; Belongs to the PI3/PI4-kinase family. (1106 aa)
PPP2R5ASerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform. (426 aa)
ADRA1BAlpha-1B adrenergic receptor. (403 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1194 aa)
PIK3R5Phosphoinositide 3-kinase regulatory subunit 5. (869 aa)
PPP2CASerine/threonine-protein phosphatase. (275 aa)
PPP2R5CSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform. (541 aa)
ADRA1DAlpha-1D adrenergic receptor. (354 aa)
CREB1Cyclic AMP-responsive element-binding protein 1. (344 aa)
TPM2Tropomyosin beta chain; Belongs to the tropomyosin family. (284 aa)
PPP2R5ESerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform. (383 aa)
CREB5Cyclic AMP-responsive element-binding protein 5. (455 aa)
CACNA2D3Voltage-dependent calcium channel subunit alpha-2/delta-3. (976 aa)
MYL4Myosin light chain, embryonic. (181 aa)
PRKCAProtein kinase C alpha type; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (606 aa)
TPM1Tropomyosin alpha-1 chain; Belongs to the tropomyosin family. (282 aa)
PLNCardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. (52 aa)
PPP2R3CSerine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma. (433 aa)
CREB3L1Cyclic AMP-responsive element-binding protein 3-like 1. (499 aa)
Your Current Organism:
Egretta garzetta
NCBI taxonomy Id: 188379
Other names: E. garzetta, little egret
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