STRINGSTRING
AOH46951.1 AOH46951.1 AOH47040.1 AOH47040.1 AOH47042.1 AOH47042.1 sucD sucD sucC sucC AOH47122.1 AOH47122.1 AOH47124.1 AOH47124.1 AOH47137.1 AOH47137.1 AOH47140.1 AOH47140.1 AOH47141.1 AOH47141.1 AOH47142.1 AOH47142.1 AOH47143.1 AOH47143.1 AOH47198.1 AOH47198.1 AOH47199.1 AOH47199.1 AOH47223.1 AOH47223.1 AOH47224.1 AOH47224.1 AOH47225.1 AOH47225.1 AOH47226.1 AOH47226.1 AOH47276.1 AOH47276.1 AOH47277.1 AOH47277.1 AOH47280.1 AOH47280.1 fumC fumC AOH47351.1 AOH47351.1 AOH47354.1 AOH47354.1 AOH47358.1 AOH47358.1 pckA pckA leuA leuA birA birA AOH47781.1 AOH47781.1 AOH47806.1 AOH47806.1 AOH47857.1 AOH47857.1 ilvD ilvD AOH47908.1 AOH47908.1 mdh mdh AOH48255.1 AOH48255.1 AOH48371.1 AOH48371.1 AOH48372.1 AOH48372.1 AOH48373.1 AOH48373.1 AOH48374.1 AOH48374.1 AOH48375.1 AOH48375.1 AOH48450.1 AOH48450.1 AOH49055.1 AOH49055.1 AOH48514.1 AOH48514.1 leuB leuB leuD leuD leuC leuC ilvC ilvC AOH48627.1 AOH48627.1 AOH48660.1 AOH48660.1 AOH48661.1 AOH48661.1 AOH48662.1 AOH48662.1 AOH48663.1 AOH48663.1 AOH48664.1 AOH48664.1 AOH48665.1 AOH48665.1 AOH48666.1 AOH48666.1 AOH48700.1 AOH48700.1 AOH48703.1 AOH48703.1 AOH48704.1 AOH48704.1 BCS37_09840 BCS37_09840 AOH48761.1 AOH48761.1 AOH48763.1 AOH48763.1 AOH48787.1 AOH48787.1 AOH48788.1 AOH48788.1 AOH48789.1 AOH48789.1 AOH48790.1 AOH48790.1 AOH48828.1 AOH48828.1 AOH48829.1 AOH48829.1 AOH48889.1 AOH48889.1 AOH48970.1 AOH48970.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AOH46951.1Butanol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (394 aa)
AOH47040.1Malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate; Derived by automated computational analysis using gene prediction method: Protein Homology. (542 aa)
AOH47042.1Diaminopropionate ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (399 aa)
sucDsuccinate--CoA ligase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (301 aa)
sucCsuccinate--CoA ligase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (396 aa)
AOH47122.1Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (255 aa)
AOH47124.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (209 aa)
AOH47137.1L-lactate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LDH/MDH superfamily. (319 aa)
AOH47140.12-oxoglutarate ferredoxin oxidoreductase subunit gamma; Catalyzes the ferredoxin-dependent oxidative decarboxylation 2-oxoglutarate forming succinyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (176 aa)
AOH47141.12-oxoglutarate ferredoxin oxidoreductase subunit beta; Catalyzes the coenzyme A-dependent formation of succinyl-CoA from 2-oxoglutarate and ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (283 aa)
AOH47142.12-oxoglutarate synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (383 aa)
AOH47143.14Fe-4S ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (66 aa)
AOH47198.1Regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (123 aa)
AOH47199.1Pyruvate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pyruvate kinase family. (471 aa)
AOH47223.1Formate dehydrogenase-N subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (1005 aa)
AOH47224.1Formate dehydrogenase; Necessary for formate dehydrogenase activity. Belongs to the FdhE family. (290 aa)
AOH47225.1Formate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (274 aa)
AOH47226.1Formate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (231 aa)
AOH47276.1L(+)-tartrate dehydratase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (299 aa)
AOH47277.1L(+)-tartrate dehydratase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. (203 aa)
AOH47280.1Acetolactate synthase, large subunit, biosynthetic type; Derived by automated computational analysis using gene prediction method: Protein Homology. (554 aa)
fumCFumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (454 aa)
AOH47351.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (216 aa)
AOH47354.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (349 aa)
AOH47358.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (142 aa)
pckAPhosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (539 aa)
leuA2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (555 aa)
birAbiotin--[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. (326 aa)
AOH47781.1Threonine ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (415 aa)
AOH47806.1Pyruvate:ferredoxin (flavodoxin) oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1175 aa)
AOH47857.1Tartrate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (354 aa)
ilvDDihydroxy-acid dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family. (550 aa)
AOH47908.1Converts oxaloacetate to phosphoenolpyruvate using ATP as an energy source; Derived by automated computational analysis using gene prediction method: Protein Homology. (462 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (316 aa)
AOH48255.1Radical SAM protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (219 aa)
AOH48371.1Succinate dehydrogenase iron-sulfur subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (250 aa)
AOH48372.1Succinate dehydrogenase flavoprotein subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (603 aa)
AOH48373.1Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (210 aa)
AOH48374.1Fumarate hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (185 aa)
AOH48375.1Fumarate hydratase; Catalyzes the reversible hydration of fumaric acid to yield I-malic acid; Derived by automated computational analysis using gene prediction method: Protein Homology. (280 aa)
AOH48450.1Acetolactate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (166 aa)
AOH49055.1Acetolactate synthase, large subunit, biosynthetic type; Derived by automated computational analysis using gene prediction method: Protein Homology. (561 aa)
AOH48514.1Branched chain amino acid aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (341 aa)
leuB3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (357 aa)
leuD3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily. (167 aa)
leuC3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (420 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (337 aa)
AOH48627.1Acetolactate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (176 aa)
AOH48660.1Composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism; Derived by automated computational analysis using gene prediction method: Protein Homology. (131 aa)
AOH48661.1methylmalonyl-CoA carboxyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (509 aa)
AOH48662.1methylmalonyl-CoA epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (138 aa)
AOH48663.1GTPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (312 aa)
AOH48664.1methylmalonyl-CoA mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (131 aa)
AOH48665.1methylmalonyl-CoA mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (548 aa)
AOH48666.1acetyl-CoA hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (498 aa)
AOH48700.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (222 aa)
AOH48703.1Pyruvate formate-lyase 1-activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family. (251 aa)
AOH48704.1Formate C-acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (749 aa)
BCS37_09840(2Fe-2S)-binding protein; Incomplete; partial on complete genome; missing start; Derived by automated computational analysis using gene prediction method: Protein Homology. (289 aa)
AOH48761.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (543 aa)
AOH48763.1Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family. (611 aa)
AOH48787.1Peptide methionine sulfoxide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (185 aa)
AOH48788.1ATPase/protein kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (392 aa)
AOH48789.1methylmalonyl-CoA mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (732 aa)
AOH48790.1methylmalonyl-CoA mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (728 aa)
AOH48828.1glutaconyl-CoA decarboxylase subunit beta; Tunnel subunit of the primary sodium pump glutaconyl-CoA decarboxylase (GCD). (375 aa)
AOH48829.1methylmalonyl-CoA decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (116 aa)
AOH48889.1Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (229 aa)
AOH48970.1Malate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (414 aa)
Your Current Organism:
Selenomonas
NCBI taxonomy Id: 1884263
Other names: S. sp. oral taxon 920, Selenomonas sp. oral taxon 920
Server load: low (38%) [HD]