STRINGSTRING
AOH47042.1 AOH47042.1 AOH47069.1 AOH47069.1 AOH47098.1 AOH47098.1 AOH47122.1 AOH47122.1 AOH47124.1 AOH47124.1 AOH47137.1 AOH47137.1 AOH47141.1 AOH47141.1 AOH48993.1 AOH48993.1 bioD bioD bioA bioA pheA pheA AOH47197.1 AOH47197.1 AOH47199.1 AOH47199.1 AOH47228.1 AOH47228.1 AOH47230.1 AOH47230.1 serS serS AOH47255.1 AOH47255.1 gltX gltX AOH47278.1 AOH47278.1 aroC aroC aroK aroK aroB aroB fumC fumC AOH47339.1 AOH47339.1 AOH47343.1 AOH47343.1 AOH47344.1 AOH47344.1 AOH47351.1 AOH47351.1 AOH47354.1 AOH47354.1 AOH47356.1 AOH47356.1 AOH47358.1 AOH47358.1 AOH47359.1 AOH47359.1 mtnA mtnA pgk pgk tpiA tpiA gpmI gpmI AOH47375.1 AOH47375.1 AOH49003.1 AOH49003.1 eno eno AOH47409.1 AOH47409.1 AOH47425.1 AOH47425.1 AOH47432.1 AOH47432.1 dapB dapB asd asd AOH47453.1 AOH47453.1 AOH47474.1 AOH47474.1 AOH47512.1 AOH47512.1 AOH47514.1 AOH47514.1 leuS leuS bioB bioB AOH47533.1 AOH47533.1 kbaY kbaY AOH47540.1 AOH47540.1 BCS37_03450 BCS37_03450 pfp pfp dapA dapA AOH47624.1 AOH47624.1 AOH47626.1 AOH47626.1 AOH47627.1 AOH47627.1 AOH47628.1 AOH47628.1 glnS glnS leuA leuA argS argS pyrG pyrG hisS hisS aspS aspS AOH47734.1 AOH47734.1 glyQ glyQ glyS glyS trpF trpF AOH47761.1 AOH47761.1 trpB trpB trpA trpA AOH47781.1 AOH47781.1 AOH47793.1 AOH47793.1 AOH47815.1 AOH47815.1 AOH47816.1 AOH47816.1 AOH47817.1 AOH47817.1 cbiA cbiA cobQ cobQ ispH ispH thrB thrB argC argC argJ argJ argB argB argD argD AOH47846.1 AOH47846.1 argG argG argH argH AOH47852.1 AOH47852.1 AOH47857.1 AOH47857.1 AOH47864.1 AOH47864.1 AOH47865.1 AOH47865.1 AOH47866.1 AOH47866.1 tyrS tyrS ilvD ilvD alaS alaS hisZ hisZ hisG hisG hisD hisD hisC hisC hisB hisB hisH hisH hisA hisA hisF hisF hisI hisI AOH47909.1 AOH47909.1 purF purF proA proA proB proB guaA guaA AOH47960.1 AOH47960.1 mdh mdh lysS lysS dtd dtd carB carB carA carA pyrB pyrB glmS glmS AOH48015.1 AOH48015.1 AOH48018.1 AOH48018.1 aroA aroA AOH49039.1 AOH49039.1 AOH48125.1 AOH48125.1 AOH48134.1 AOH48134.1 AOH48163.1 AOH48163.1 acpP acpP AOH48167.1 AOH48167.1 fabH fabH plsX plsX aroE aroE ispF ispF ispD ispD pheT pheT pheS pheS thrS thrS AOH48275.1 AOH48275.1 AOH48308.1 AOH48308.1 cysS cysS AOH48321.1 AOH48321.1 ispE ispE AOH48343.1 AOH48343.1 ispG ispG AOH48364.1 AOH48364.1 AOH48365.1 AOH48365.1 AOH48366.1 AOH48366.1 trpD trpD AOH48379.1 AOH48379.1 glyA glyA proC proC AOH48410.1 AOH48410.1 ileS ileS AOH48415.1 AOH48415.1 AOH48437.1 AOH48437.1 AOH48439.1 AOH48439.1 AOH48441.1 AOH48441.1 AOH48450.1 AOH48450.1 AOH48514.1 AOH48514.1 acpS acpS AOH48533.1 AOH48533.1 dapF dapF AOH48551.1 AOH48551.1 AOH48554.1 AOH48554.1 kdsA kdsA fabZ fabZ leuB leuB leuD leuD leuC leuC ilvC ilvC AOH48627.1 AOH48627.1 AOH48630.1 AOH48630.1 metAA metAA AOH48646.1 AOH48646.1 AOH48652.1 AOH48652.1 AOH48660.1 AOH48660.1 AOH48661.1 AOH48661.1 AOH48664.1 AOH48664.1 AOH48666.1 AOH48666.1 valS valS folD folD AOH48709.1 AOH48709.1 AOH48717.1 AOH48717.1 BCS37_09840 BCS37_09840 AOH48761.1 AOH48761.1 AOH48767.1 AOH48767.1 AOH48770.1 AOH48770.1 AOH48771.1 AOH48771.1 AOH48779.1 AOH48779.1 pfkA pfkA metG metG AOH48828.1 AOH48828.1 AOH48829.1 AOH48829.1 serC serC AOH48868.1 AOH48868.1 AOH48886.1 AOH48886.1 AOH48887.1 AOH48887.1 AOH48889.1 AOH48889.1 trpS trpS AOH48902.1 AOH48902.1 AOH48909.1 AOH48909.1 pfkA-2 pfkA-2 nanE nanE nagB nagB AOH46953.1 AOH46953.1 AOH46998.1 AOH46998.1 BCS37_00415 BCS37_00415 AOH47004.1 AOH47004.1 AOH47007.1 AOH47007.1 AOH47014.1 AOH47014.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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AOH47042.1Diaminopropionate ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (399 aa)
AOH47069.1acyl-CoA thioesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (187 aa)
AOH47098.1Fructose bisphosphate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (295 aa)
AOH47122.1Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (255 aa)
AOH47124.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (209 aa)
AOH47137.1L-lactate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LDH/MDH superfamily. (319 aa)
AOH47141.12-oxoglutarate ferredoxin oxidoreductase subunit beta; Catalyzes the coenzyme A-dependent formation of succinyl-CoA from 2-oxoglutarate and ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (283 aa)
AOH48993.1Peptidase M20; Derived by automated computational analysis using gene prediction method: Protein Homology. (435 aa)
bioDDethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. (226 aa)
bioAAdenosylmethionine--8-amino-7-oxononanoate transaminase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. (447 aa)
pheAPrephenate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (285 aa)
AOH47197.13-deoxy-7-phosphoheptulonate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (344 aa)
AOH47199.1Pyruvate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pyruvate kinase family. (471 aa)
AOH47228.1Cysteine synthase A; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cysteine synthase/cystathionine beta- synthase family. (311 aa)
AOH47230.1Cystathionine gamma-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (384 aa)
serSserine--tRNA ligase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (423 aa)
AOH47255.13-hydroxybutyryl-CoA dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family. (259 aa)
gltXglutamate--tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (474 aa)
AOH47278.1Methionine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (370 aa)
aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (389 aa)
aroKShikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (173 aa)
aroB3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (361 aa)
fumCFumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (454 aa)
AOH47339.1ATP-dependent carboxylate-amine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (310 aa)
AOH47343.1UDP-glucose 6-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (388 aa)
AOH47344.1Asparagine synthase (glutamine-hydrolyzing); Derived by automated computational analysis using gene prediction method: Protein Homology. (631 aa)
AOH47351.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (216 aa)
AOH47354.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (349 aa)
AOH47356.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (281 aa)
AOH47358.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (142 aa)
AOH47359.1Acyl carrier protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (80 aa)
mtnAS-methyl-5-thioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). (350 aa)
pgkPhosphoglycerate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phosphoglycerate kinase family. (397 aa)
tpiATriose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (249 aa)
gpmIPhosphoglycerate mutase (2,3-diphosphoglycerate-independent); Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (518 aa)
AOH47375.1Hexokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (430 aa)
AOH49003.1Glucose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (482 aa)
enoPhosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (434 aa)
AOH47409.1Phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (531 aa)
AOH47425.1Phosphoribosylformylglycinamidine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1263 aa)
AOH47432.1Threonine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (497 aa)
dapB4-hydroxy-tetrahydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (262 aa)
asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (343 aa)
AOH47453.1Chorismate mutase; Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis. (119 aa)
AOH47474.1Phosphoadenosine phosphosulfate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (268 aa)
AOH47512.1Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (368 aa)
AOH47514.1Alanine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the AlaDH/PNT family. (373 aa)
leuSleucine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. (824 aa)
bioBBiotin synthase BioB; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (336 aa)
AOH47533.1Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (380 aa)
kbaYTagatose-bisphosphate aldolase; Catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases: KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway; Derived by automated computational analysis using gene prediction method: Protein Homology. (283 aa)
AOH47540.1Aminotransferase class III; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (437 aa)
BCS37_03450Aminotransferase; Internal stop; Derived by automated computational analysis using gene prediction method: Protein Homology. (376 aa)
pfp6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (420 aa)
dapA4-hydroxy-tetrahydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (295 aa)
AOH47624.1Homocysteine S-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (310 aa)
AOH47626.1Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (280 aa)
AOH47627.1Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (124 aa)
AOH47628.12-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (321 aa)
glnSglutamine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (556 aa)
leuA2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (555 aa)
argSarginine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (552 aa)
pyrGCTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (536 aa)
hisShistidine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (421 aa)
aspSaspartate--tRNA ligase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (602 aa)
AOH47734.1CtsR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (150 aa)
glyQglycine--tRNA ligase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (293 aa)
glySglycine--tRNA ligase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. (683 aa)
trpFPhosphoribosylanthranilate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TrpF family. (204 aa)
AOH47761.1Indole-3-glycerol phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (261 aa)
trpBTryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (395 aa)
trpATryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (261 aa)
AOH47781.1Threonine ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (415 aa)
AOH47793.1Cysteine desulfurase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. (412 aa)
AOH47815.1GNAT family N-acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the acetyltransferase family. (149 aa)
AOH47816.13-deoxy-7-phosphoheptulonate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (337 aa)
AOH47817.1Arogenate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (296 aa)
cbiACobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. (455 aa)
cobQCobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (507 aa)
ispH4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (276 aa)
thrBHomoserine dehydrogenase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (316 aa)
argCN-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (344 aa)
argJBifunctional ornithine acetyltransferase/N-acetylglutamate synthase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (403 aa)
argBAcetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (294 aa)
argDAcetylornithine aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (405 aa)
AOH47846.1Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (311 aa)
argGArgininosuccinate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (404 aa)
argHArgininosuccinate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (474 aa)
AOH47852.1Transketolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (313 aa)
AOH47857.1Tartrate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (354 aa)
AOH47864.1Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (413 aa)
AOH47865.1Aspartate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartokinase family. (409 aa)
AOH47866.1Fructose-1,6-bisphosphate aldolase, class II; Derived by automated computational analysis using gene prediction method: Protein Homology. (332 aa)
tyrStyrosine--tRNA ligase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. (400 aa)
ilvDDihydroxy-acid dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family. (550 aa)
alaSalanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (873 aa)
hisZATP phosphoribosyltransferase regulatory subunit; Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine. (392 aa)
hisGATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. (221 aa)
hisDHistidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (451 aa)
hisCHistidinol-phosphate transaminase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (354 aa)
hisBImidazoleglycerol-phosphate dehydratase; Catalyzes the dehydration of D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate to 3-(imidazol-4-yl)-2-oxopropyl phosphate in histidine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. (199 aa)
hisHImidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (209 aa)
hisA1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxamide isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (240 aa)
hisFImidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (266 aa)
hisIBifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology; In the N-terminal section; belongs to the PRA-CH family. (234 aa)
AOH47909.1AAA family ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (538 aa)
purFAmidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (483 aa)
proAGlutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (416 aa)
proBGlutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (374 aa)
guaAGlutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. (518 aa)
AOH47960.1Agmatinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the arginase family. (293 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (316 aa)
lysSlysine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family. (503 aa)
dtdD-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. (147 aa)
carBCarbamoyl phosphate synthase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CarB family. (1075 aa)
carACarbamoyl phosphate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CarA family. (357 aa)
pyrBAspartate carbamoyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (314 aa)
glmSGlutamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (609 aa)
AOH48015.1Radical SAM protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (425 aa)
AOH48018.1Glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (449 aa)
aroA3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (435 aa)
AOH49039.1FAD-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (416 aa)
AOH48125.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (95 aa)
AOH48134.1DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (301 aa)
AOH48163.1Beta-ketoacyl-[acyl-carrier-protein] synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (414 aa)
acpPAcyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (76 aa)
AOH48167.1[acyl-carrier-protein] S-malonyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (311 aa)
fabH3-oxoacyl-ACP synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (334 aa)
plsXPhosphate acyltransferase; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (337 aa)
aroEShikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (286 aa)
ispF2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). (158 aa)
ispD2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). (256 aa)
pheTphenylalanine--tRNA ligase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. (811 aa)
pheSphenylalanine--tRNA ligase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. (342 aa)
thrSthreonine--tRNA ligase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). (639 aa)
AOH48275.1Pyridine nucleotide-disulfide oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (409 aa)
AOH48308.1Glutamine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family. (629 aa)
cysScysteine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. (475 aa)
AOH48321.1Serine O-acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (240 aa)
ispE4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (292 aa)
AOH48343.1phenylacetate--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (309 aa)
ispGproline--tRNA ligase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (359 aa)
AOH48364.1Homocysteine methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (596 aa)
AOH48365.1Homocysteine methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (802 aa)
AOH48366.1Methionine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (229 aa)
trpDAnthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (338 aa)
AOH48379.1F420-0:Gamma-glutamyl ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (220 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (415 aa)
proCPyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (270 aa)
AOH48410.1Metal-dependent hydrolase; Catalyzes the opening and hydrolysis of the beta-lactam ring of beta-lactam antibiotics such as penicillins and cephalosporins; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0173 family. (225 aa)
ileSisoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. (1039 aa)
AOH48415.1Quinone oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (319 aa)
AOH48437.1Fructose-bisphosphate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (278 aa)
AOH48439.1Triose-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (235 aa)
AOH48441.1Arginase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the arginase family. (311 aa)
AOH48450.1Acetolactate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (166 aa)
AOH48514.1Branched chain amino acid aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (341 aa)
acpSHolo-[acyl-carrier-protein] synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. (125 aa)
AOH48533.1DJ-1/PfpI family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (205 aa)
dapFDiaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (279 aa)
AOH48551.1Phosphogluconate dehydrogenase (NADP(+)-dependent, decarboxylating); Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (474 aa)
AOH48554.1L-ascorbate 6-phosphate lactonase; Derived by automated computational analysis using gene prediction method: Protein Homology. (349 aa)
kdsA3-deoxy-8-phosphooctulonate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the KdsA family. (275 aa)
fabZ3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (146 aa)
leuB3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (357 aa)
leuD3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily. (167 aa)
leuC3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (420 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (337 aa)
AOH48627.1Acetolactate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (176 aa)
AOH48630.1Diaminopimelate dehydrogenase; Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate. (326 aa)
metAAHomoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. (315 aa)
AOH48646.1Histidinol-phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the PHP hydrolase family. HisK subfamily. (283 aa)
AOH48652.1Hexokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (429 aa)
AOH48660.1Composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism; Derived by automated computational analysis using gene prediction method: Protein Homology. (131 aa)
AOH48661.1methylmalonyl-CoA carboxyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (509 aa)
AOH48664.1methylmalonyl-CoA mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (131 aa)
AOH48666.1acetyl-CoA hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (498 aa)
valSvaline--tRNA ligase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (887 aa)
folDMethenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (288 aa)
AOH48709.1L-asparaginase 1; Derived by automated computational analysis using gene prediction method: Protein Homology. (310 aa)
AOH48717.1Diaminopimelate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (419 aa)
BCS37_09840(2Fe-2S)-binding protein; Incomplete; partial on complete genome; missing start; Derived by automated computational analysis using gene prediction method: Protein Homology. (289 aa)
AOH48761.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (543 aa)
AOH48767.1Dihydrodipicolinate synthase family protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DapA family. (297 aa)
AOH48770.12-dehydro-3-deoxygalactonokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (329 aa)
AOH48771.1Hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (337 aa)
AOH48779.1Phosphogluconate dehydrogenase (NADP(+)-dependent, decarboxylating); Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (476 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (321 aa)
metGmethionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (514 aa)
AOH48828.1glutaconyl-CoA decarboxylase subunit beta; Tunnel subunit of the primary sodium pump glutaconyl-CoA decarboxylase (GCD). (375 aa)
AOH48829.1methylmalonyl-CoA decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (116 aa)
serCPhosphoserine transaminase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (361 aa)
AOH48868.1O-acetylhomoserine aminocarboxypropyltransferase; Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol; Derived by automated computational analysis using gene prediction method: Protein Homology. (429 aa)
AOH48886.1Ketose-bisphosphate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (277 aa)
AOH48887.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the AB hydrolase superfamily. MetX family. (361 aa)
AOH48889.1Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (229 aa)
trpStryptophan--tRNA ligase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. (336 aa)
AOH48902.1Phosphoenolpyruvate mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (431 aa)
AOH48909.1Phosphonopyruvate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (370 aa)
pfkA-26-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (320 aa)
nanEN-acetylmannosamine-6-phosphate 2-epimerase; Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N- acetylglucosamine-6-phosphate (GlcNAc-6-P). (223 aa)
nagBGlucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. (247 aa)
AOH46953.1Threonine aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (343 aa)
AOH46998.1Threonine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (333 aa)
BCS37_00415Hypothetical protein; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. (411 aa)
AOH47004.1Serine hydroxymethyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (440 aa)
AOH47007.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (284 aa)
AOH47014.1Hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (320 aa)
Your Current Organism:
Selenomonas
NCBI taxonomy Id: 1884263
Other names: S. sp. oral taxon 920, Selenomonas sp. oral taxon 920
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