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AOH46960.1 AOH46960.1 AOH46961.1 AOH46961.1 BCS37_00415 BCS37_00415 AOH47004.1 AOH47004.1 AOH47009.1 AOH47009.1 AOH47010.1 AOH47010.1 AOH47014.1 AOH47014.1 AOH47015.1 AOH47015.1 AOH47098.1 AOH47098.1 sucD sucD sucC sucC AOH47140.1 AOH47140.1 AOH47141.1 AOH47141.1 AOH47142.1 AOH47142.1 AOH47143.1 AOH47143.1 AOH47199.1 AOH47199.1 AOH47223.1 AOH47223.1 AOH47225.1 AOH47225.1 AOH47226.1 AOH47226.1 AOH47228.1 AOH47228.1 fumC fumC AOH49002.1 AOH49002.1 AOH47357.1 AOH47357.1 AOH47358.1 AOH47358.1 AOH47367.1 AOH47367.1 pgk pgk tpiA tpiA gpmI gpmI AOH47375.1 AOH47375.1 AOH49003.1 AOH49003.1 eno eno AOH47409.1 AOH47409.1 pckA pckA AOH47452.1 AOH47452.1 AOH47535.1 AOH47535.1 pfp pfp AOH47729.1 AOH47729.1 AOH47764.1 AOH47764.1 AOH47781.1 AOH47781.1 AOH47806.1 AOH47806.1 AOH47851.1 AOH47851.1 AOH47852.1 AOH47852.1 AOH47866.1 AOH47866.1 mdh mdh AOH48321.1 AOH48321.1 prs prs AOH48371.1 AOH48371.1 AOH48372.1 AOH48372.1 AOH48373.1 AOH48373.1 AOH48374.1 AOH48374.1 AOH48375.1 AOH48375.1 glyA glyA AOH48386.1 AOH48386.1 AOH48439.1 AOH48439.1 AOH48551.1 AOH48551.1 AOH48652.1 AOH48652.1 AOH48662.1 AOH48662.1 AOH48664.1 AOH48664.1 AOH48665.1 AOH48665.1 AOH48666.1 AOH48666.1 fhs fhs folD folD BCS37_09840 BCS37_09840 AOH48768.1 AOH48768.1 AOH48769.1 AOH48769.1 AOH48771.1 AOH48771.1 AOH48779.1 AOH48779.1 AOH48782.1 AOH48782.1 pfkA pfkA AOH48789.1 AOH48789.1 AOH48790.1 AOH48790.1 serC serC AOH48886.1 AOH48886.1 pfkA-2 pfkA-2 AOH48970.1 AOH48970.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AOH46960.12-dehydro-3-deoxyphosphogluconate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (214 aa)
AOH46961.12-dehydro-3-deoxygluconokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (318 aa)
BCS37_00415Hypothetical protein; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. (411 aa)
AOH47004.1Serine hydroxymethyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (440 aa)
AOH47009.1Transketolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (273 aa)
AOH47010.1Transketolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (312 aa)
AOH47014.1Hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (320 aa)
AOH47015.1Glycerate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (409 aa)
AOH47098.1Fructose bisphosphate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (295 aa)
sucDsuccinate--CoA ligase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (301 aa)
sucCsuccinate--CoA ligase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (396 aa)
AOH47140.12-oxoglutarate ferredoxin oxidoreductase subunit gamma; Catalyzes the ferredoxin-dependent oxidative decarboxylation 2-oxoglutarate forming succinyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (176 aa)
AOH47141.12-oxoglutarate ferredoxin oxidoreductase subunit beta; Catalyzes the coenzyme A-dependent formation of succinyl-CoA from 2-oxoglutarate and ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (283 aa)
AOH47142.12-oxoglutarate synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (383 aa)
AOH47143.14Fe-4S ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (66 aa)
AOH47199.1Pyruvate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pyruvate kinase family. (471 aa)
AOH47223.1Formate dehydrogenase-N subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (1005 aa)
AOH47225.1Formate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (274 aa)
AOH47226.1Formate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (231 aa)
AOH47228.1Cysteine synthase A; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cysteine synthase/cystathionine beta- synthase family. (311 aa)
fumCFumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (454 aa)
AOH49002.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (266 aa)
AOH47357.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (304 aa)
AOH47358.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (142 aa)
AOH47367.1Type I glyceraldehyde-3-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (337 aa)
pgkPhosphoglycerate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phosphoglycerate kinase family. (397 aa)
tpiATriose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (249 aa)
gpmIPhosphoglycerate mutase (2,3-diphosphoglycerate-independent); Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (518 aa)
AOH47375.1Hexokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (430 aa)
AOH49003.1Glucose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (482 aa)
enoPhosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (434 aa)
AOH47409.1Phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (531 aa)
pckAPhosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (539 aa)
AOH47452.1Ribose 5-phosphate isomerase B; Derived by automated computational analysis using gene prediction method: Protein Homology. (150 aa)
AOH47535.11-phosphofructokinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the carbohydrate kinase PfkB family. LacC subfamily. (306 aa)
pfp6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (420 aa)
AOH47729.1Ribulose-phosphate 3-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribulose-phosphate 3-epimerase family. (236 aa)
AOH47764.1Fructose-bisphosphate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (227 aa)
AOH47781.1Threonine ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (415 aa)
AOH47806.1Pyruvate:ferredoxin (flavodoxin) oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1175 aa)
AOH47851.1Transketolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (283 aa)
AOH47852.1Transketolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (313 aa)
AOH47866.1Fructose-1,6-bisphosphate aldolase, class II; Derived by automated computational analysis using gene prediction method: Protein Homology. (332 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (316 aa)
AOH48321.1Serine O-acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (240 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (317 aa)
AOH48371.1Succinate dehydrogenase iron-sulfur subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (250 aa)
AOH48372.1Succinate dehydrogenase flavoprotein subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (603 aa)
AOH48373.1Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (210 aa)
AOH48374.1Fumarate hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (185 aa)
AOH48375.1Fumarate hydratase; Catalyzes the reversible hydration of fumaric acid to yield I-malic acid; Derived by automated computational analysis using gene prediction method: Protein Homology. (280 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (415 aa)
AOH48386.1Ribose 5-phosphate isomerase B; Derived by automated computational analysis using gene prediction method: Protein Homology. (150 aa)
AOH48439.1Triose-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (235 aa)
AOH48551.1Phosphogluconate dehydrogenase (NADP(+)-dependent, decarboxylating); Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (474 aa)
AOH48652.1Hexokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (429 aa)
AOH48662.1methylmalonyl-CoA epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (138 aa)
AOH48664.1methylmalonyl-CoA mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (131 aa)
AOH48665.1methylmalonyl-CoA mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (548 aa)
AOH48666.1acetyl-CoA hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (498 aa)
fhsCholine-sulfatase; Incomplete; partial on complete genome; missing start; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the formate--tetrahydrofolate ligase family. (554 aa)
folDMethenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (288 aa)
BCS37_09840(2Fe-2S)-binding protein; Incomplete; partial on complete genome; missing start; Derived by automated computational analysis using gene prediction method: Protein Homology. (289 aa)
AOH48768.12-dehydro-3-deoxygluconokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (315 aa)
AOH48769.12-dehydro-3-deoxy-6-phosphogalactonate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (220 aa)
AOH48771.1Hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (337 aa)
AOH48779.1Phosphogluconate dehydrogenase (NADP(+)-dependent, decarboxylating); Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (476 aa)
AOH48782.1Gluconate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FGGY kinase family. (515 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (321 aa)
AOH48789.1methylmalonyl-CoA mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (732 aa)
AOH48790.1methylmalonyl-CoA mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (728 aa)
serCPhosphoserine transaminase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (361 aa)
AOH48886.1Ketose-bisphosphate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (277 aa)
pfkA-26-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (320 aa)
AOH48970.1Malate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (414 aa)
Your Current Organism:
Selenomonas
NCBI taxonomy Id: 1884263
Other names: S. sp. oral taxon 920, Selenomonas sp. oral taxon 920
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