STRINGSTRING
AMM06705.1 AMM06705.1 AMM06861.1 AMM06861.1 AMM07044.1 AMM07044.1 AMM07404.1 AMM07404.1 AMM07522.1 AMM07522.1 AMM07528.1 AMM07528.1 dut dut AMM07849.1 AMM07849.1 nrdR nrdR AMM07861.1 AMM07861.1 thyX thyX AMM07928.1 AMM07928.1 AMM08016.1 AMM08016.1 AMM08366.1 AMM08366.1 AMM08367.1 AMM08367.1 AMM08582.1 AMM08582.1 AMM08826.1 AMM08826.1 AMM09407.1 AMM09407.1 nudF nudF dcd dcd folE folE AMM10313.1 AMM10313.1 adk adk AMM10762.1 AMM10762.1 ndk ndk AMM11296.1 AMM11296.1 AMM11576.1 AMM11576.1 pyrG pyrG AMM11762.1 AMM11762.1 AMM11763.1 AMM11763.1 AMM11764.1 AMM11764.1 AMM11765.1 AMM11765.1 AMM11766.1 AMM11766.1 AMM11767.1 AMM11767.1 AMM11768.1 AMM11768.1 AMM11769.1 AMM11769.1 cmk cmk der der AMM12007.1 AMM12007.1 AMM12044.1 AMM12044.1 AMM12108.1 AMM12108.1 AMM12109.1 AMM12109.1 AMM12110.1 AMM12110.1 ribBA ribBA ribH ribH AMM12150.1 AMM12150.1 AMM12476.1 AMM12476.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AMM06705.1Regulator of polyketide synthase expression. (645 aa)
AMM06861.1Phosphohydrolase. (322 aa)
AMM07044.1Guanosine polyphosphate pyrophosphohydrolase. (125 aa)
AMM07404.1Integral membrane protein. (145 aa)
AMM07522.1MutT/NUDIX family protein. (159 aa)
AMM07528.15-amino-6-(5-phosphoribosylamino)uracil reductase. (260 aa)
dutDeoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. (171 aa)
AMM07849.1Vitamin B12-dependent ribonucleotide reductase; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. (957 aa)
nrdRTranscriptional repressor NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. (170 aa)
AMM07861.1ppGpp synthetase/hydrolase. (723 aa)
thyXThymidylate synthase thyX; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. (246 aa)
AMM07928.1Riboflavin kinase / FMN adenylyltransferase; Belongs to the ribF family. (321 aa)
AMM08016.1Chromosome segregation protein SMC. (1295 aa)
AMM08366.1Ribonucleotide reductase of class Ia (aerobic), alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (791 aa)
AMM08367.1Ribonucleotide reductase of class Ia (aerobic), beta subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. (350 aa)
AMM08582.1Secreted protein. (511 aa)
AMM08826.1Cellulose-binding protein. (330 aa)
AMM09407.1Thymidylate kinase. (1103 aa)
nudFADP-ribose pyrophosphatase. (177 aa)
dcdDeoxycytidine triphosphate deaminase; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate. (191 aa)
folEGTP cyclohydrolase I type 1. (201 aa)
AMM10313.1Hydrolase. (344 aa)
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (218 aa)
AMM10762.1NUDIX hydrolase. (180 aa)
ndkNucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (137 aa)
AMM11296.1NGG1-interacting factor 3. (288 aa)
AMM11576.1HAD-superfamily hydrolase. (227 aa)
pyrGCTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (556 aa)
AMM11762.1ATPases involved in chromosome partitioning. (330 aa)
AMM11763.1Hypothetical protein. (188 aa)
AMM11764.1Segregation and condensation protein A; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves. (349 aa)
AMM11765.1Segregation and condensation protein B; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves. (219 aa)
AMM11766.1Pseudouridine synthase; Belongs to the pseudouridine synthase RsuA family. (351 aa)
AMM11767.1DNA hydrolase. (234 aa)
AMM11768.1Glycohydrolase. (336 aa)
AMM11769.1Nucleotidyltransferase. (260 aa)
cmkCytidylate kinase. (233 aa)
derGTPase Der; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. (487 aa)
AMM12007.1rRNA methylase. (267 aa)
AMM12044.1(P)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (836 aa)
AMM12108.1Riboflavin biosynthesis protein RibD. (378 aa)
AMM12109.1Riboflavin synthase alpha chain. (207 aa)
AMM12110.1Integral membrane protein. (216 aa)
ribBA3, 4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. (433 aa)
ribH6, 7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. (161 aa)
AMM12150.1Hypothetical protein. (360 aa)
AMM12476.1Hypothetical protein. (122 aa)
Your Current Organism:
Streptomyces albus
NCBI taxonomy Id: 1888
Other names: AS 4.164, ATCC 25426, ATCC 25427 [[Streptomyces almquistii]], ATCC 25453 [[Streptomyces flocculus]], ATCC 25490 [[Streptomyces rangoonensis]], ATCC 3004, ATCC 618 [[Streptomyces almquistii]], ATCC 6852 [[Streptomyces gibsonii]], ATCC 6860 [[Streptomyces rangoonensis]], Actinomyces Gibsoni, Actinomyces Gibsonii, Actinomyces almquisti, Actinomyces flocculus, Actinomyces rangoon, BCRC 10802, BCRC 12068 [[Streptomyces flocculus]], BCRC 12098 [[Streptomyces almquistii]], CBS 118.60 [[Streptomyces gibsonii]], CBS 119.60 [[Streptomyces gibsonii]], CBS 410.63, CBS 686.69 [[Streptomyces flocculus]], CBS 918.69 [[Streptomyces rangoonensis]], CBS 924.69, CBS 925.69 [[Streptomyces almquistii]], CCRC 10802, CCRC 12068 [[Streptomyces flocculus]], CCRC 12098 [[Streptomyces almquistii]], CCRC:10802, CCRC:12068 [[Streptomyces flocculus]], CCRC:12098 [[Streptomyces almquistii]], CCUG 33990, CECT 3077, CIP 104432, DSM 40313, DSM 40327 [[Streptomyces flocculus]], DSM 40447 [[Streptomyces almquistii]], DSM 40452 [[Streptomyces rangoonensis]], DSM 40933 [[Streptomyces griseus subsp. solvifaciens]], DSM 43284 [[Streptomyces gibsonii]], HAMBI 50 [[Streptomyces almquistii]], HUT 6613, HUT 6614 [[Streptomyces almquistii]], HUT 6615 [[Streptomyces flocculus]], HUT 6616 [[Streptomyces rangoonensis]], HUT 6617 [[Streptomyces gibsonii]], IFO 13014, IFO 13015 [[Streptomyces almquistii]], IFO 13041 [[Streptomyces flocculus]], IFO 13078 [[Streptomyces rangoonensis]], IFO 15415 [[Streptomyces gibsonii]], IFO 3710, IMET 40241, IMET 41357 [[Streptomyces rangoonensis]], IMET 43380 [[Streptomyces almquistii]], IMET 43522 [[Streptomyces flocculus]], IMET 7023 [[Streptomyces gibsonii]], IMRU 3004, ISP 5313, ISP 5327 [[Streptomyces flocculus]], ISP 5447 [[Streptomyces almquistii]], ISP 5452 [[Streptomyces rangoonensis]], JCM 4177, JCM 4450, JCM 4451 [[Streptomyces almquistii]], JCM 4476 [[Streptomyces flocculus]], JCM 4510 [[Streptomyces rangoonensis]], JCM 5061 [[Streptomyces gibsonii]], JCM 5079 [[Streptomyces griseus subsp. solvifaciens]], KCTC 9672 [[Streptomyces almquistii]], LMG 19912 [[Streptomyces gibsonii]], LMG:19912 [[Streptomyces gibsonii]], NBRC 13014, NBRC 13015 [[Streptomyces almquistii]], NBRC 13041 [[Streptomyces flocculus]], NBRC 13078 [[Streptomyces rangoonensis]], NBRC 15415 [[Streptomyces gibsonii]], NBRC 3710, NCIMB 9558, NCTC 4575 [[Streptomyces gibsonii]], NRRL 2960 [[Streptomyces flocculus]], NRRL B-12378 [[Streptomyces rangoonensis]], NRRL B-16595 [[Streptomyces rangoonensis]], NRRL B-2208, NRRL B-2465 [[Streptomyces flocculus]], NRRL B-2843 [[Streptomyces flocculus]], NRRL-ISP 5313, NRRL-ISP 5327 [[Streptomyces flocculus]], NRRL-ISP 5447 [[Streptomyces almquistii]], NRRL-ISP 5452 [[Streptomyces rangoonensis]], Nocardia gibsonii, Nocardia rangoonensis, Streptomyces almquistii, Streptomyces flocculus, Streptomyces gibsonii, Streptomyces griseus solvifaciens, Streptomyces griseus subsp. solvifaciens, Streptomyces rangoon, Streptomyces rangoonensis, Streptomyces sp. USC057, Streptotrix alba, VKM Ac-35
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